Environmental Chemistry and Ecotoxicology最新文献

{"title":"New insight into the adverse effect and molecular mechanism of thyroid disrupting chemicals on retinal cone differentiation: A case study of bisphenol S.","authors":"Liguo Qiu ,&nbsp;Shuhui Wei ,&nbsp;Meiping Guo ,&nbsp;Yunsheng Wang ,&nbsp;Liping Hao ,&nbsp;Xuefu Li ,&nbsp;Shaoguo Ru ,&nbsp;Xiaona Zhang","doi":"10.1016/j.enceco.2026.01.014","DOIUrl":"10.1016/j.enceco.2026.01.014","url":null,"abstract":"<div><div>Thyroid hormone (TH), coordinating with its receptor (TRβ), plays a conserved role in regulating retinal cone differentiation. Environmental thyroid disrupting chemicals (TDCs) exposure has been proved as an emerging cause of retinal photosensitive dysfunction; however, the molecular target and underlying mechanisms of action have not been well explored. Here, a TH- and TDCs-sensitive transgenic zebrafish, of which the TRE:<em>TRβ</em> promoter-driven mCherry expressed in red cones, was constructed. By using this model, it was revealed that bisphenol S (BPS), a widely-used plastic additive with similar structure to TH, exhibited an agonist effect on TRβ and specialized retinal progenitor cells (RPCs) into red cones in larval zebrafish retina. Then, the essential role of TRβ in both BPS- and TH- stimulated red cone differentiation was convinced by a loss-of-function study. Single cone cell transcriptomic data showed both BPS and TH diminished the phototransduction cascade in red cone cells by interfering with different aspects of the transduction process, finally causing color vision defects in larval fish. Overall, it was demonstrated that BPS exposure, mimicking TH, disturbed RPCs specifying into red (not UV) cones <em>via</em> activating TRβ signaling, which further induced photosensitive dysfunction in cone cells. Our work highlights a new way of TRβ-mediated modulation of cone differentiation fate upon TDCs exposure.</div></div>","PeriodicalId":100480,"journal":{"name":"Environmental Chemistry and Ecotoxicology","volume":"8 ","pages":"Pages 973-985"},"PeriodicalIF":8.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146022581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endophytic bacteria and fungi from atmospheric mercury bioindicator Tillandsia usneoides (Spanish moss) alleviate mercury stress and promote plant growth","authors":"Yuanqin Gao ,&nbsp;Bingcai Xiong ,&nbsp;Xiaoyu Huang ,&nbsp;Xingyue Sun ,&nbsp;Hongxia Du ,&nbsp;Ming Ma ,&nbsp;Feng Luo","doi":"10.1016/j.enceco.2026.01.004","DOIUrl":"10.1016/j.enceco.2026.01.004","url":null,"abstract":"<div><div>Gaseous elemental mercury (Hg⁰) poses significant risks to ecosystems due to its high volatility and bioavailability. However, it remains largely unknown how the endophytes of <em>Tillandsia usneoides</em> (Spanish moss), a biological indicator responds to Hg⁰. In this study, after 14 days of exposure to the vapor from 0.22 mL of liquid Hg⁰, <em>T. usneoides</em> accumulated a markedly elevated Hg content of 164, 900 ± 28, 900 μg kg⁻¹. High-throughput sequencing of 16S rRNA and ITS genes revealed that Hg⁰ exposure significantly reduced the α-diversity of endophytic bacteria and altered the β-diversity of both bacterial and fungal communities. Under Hg⁰ stress, taxonomic shifts included increased relative abundances of <em>Pseudomonas</em>, <em>Enterobacter</em>, and <em>Acidiella</em>. Functional predictions further indicated upregulated expression of key enzymes involved in Hg detoxification and antioxidant defense, such as mercuric reductase (MerA), glutathione S-transferase (GST), catalase (CAT), and superoxide dismutase (SOD). From Hg⁰-exposed <em>T. usneoides</em>, we isolated five endophytic bacteria (<em>Staphylococcus</em> sp. L3, <em>Pseudomonas</em> sp. L9, <em>Enterobacter</em> L19, <em>Enterobacter</em> L6, <em>Bacillus</em> LE) and two fungi (<em>Aspergillus</em> G1, G2), all of which demonstrated strong Hg²⁺ transformation and tolerance. Scanning electron microscopy (SEM) and energy-dispersive spectroscopy (EDS) confirmed morphological adaptations and Hg enrichment on microbial surfaces. Foliar inoculation with strains L6, LE, and G2 significantly alleviated Hg⁰-induced growth inhibition in <em>Arabidopsis thaliana</em>, enhancing biomass, leaf/root length, and root surface area, while mitigating auxin suppression. Overall, this study clarifies how <em>T. usneoides</em> endophytes respond to Hg⁰ and highlights their promising role in microbial-assisted phytoremediation of Hg⁰ pollution.</div></div>","PeriodicalId":100480,"journal":{"name":"Environmental Chemistry and Ecotoxicology","volume":"8 ","pages":"Pages 881-893"},"PeriodicalIF":8.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145976514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Source analysis of heavy metals in groundwater of centralized drinking water sources and seasonal variations of health risks in Wuzhou City, Pearl River Delta, China","authors":"Kunlong Hui ,&nbsp;Wenxiang Hu ,&nbsp;Beidou Xi ,&nbsp;Ying Yuan ,&nbsp;Haojie Lu ,&nbsp;Wenbing Tan","doi":"10.1016/j.enceco.2025.11.026","DOIUrl":"10.1016/j.enceco.2025.11.026","url":null,"abstract":"<div><div>Groundwater serves as a critical source for centralized drinking water, particularly in rapidly urbanizing regions, yet its quality is increasingly threatened by heavy metals (HMs) pollution. Systematic assessments that integrate source apportionment with seasonal health risks in such settings remain limited, hindering the development of targeted protection strategies. To assess the pollution characteristics and potential health risks of HMs in groundwater in Wuzhou City, Pearl River Delta, a total of 198 groundwater samples were collected for systematic analysis during the wet season and dry season in this study. The results show that the average concentrations of Mn, Fe and Zn are the highest in the two seasons, and Mn, Fe and As often exceed the Class III water limit. Overall, the pollution level of HMs is relatively high during the dry season. Three sources of HMs were identified by principal component analysis and the absolute principal component score - multiple linear regression model: geological background (28.67 % in the dry season and 21.45 % in the wet season), mining activities (22.70 % in the dry season and 26.52 % in the wet season), and agricultural activities (24.08 % in the dry season and 32.23 % in the wet season). The calculation results of the HMs pollution index show that the average HMs pollution index during the dry season and the wet season are 18.0 and 16.1 respectively, further confirming that groundwater pollution is more prominent during the dry season. Health risk assessment and Monte Carlo simulation indicate that the non-carcinogenic risk of children is slightly higher than that of adults. The spatial distribution characteristics indicate that the health risks in the northwest of the study area are more severe. Based on the comprehensive pollution characteristics and risk assessment results, Mn, Fe and As were identified as characteristic pollutants that need to be prioritized for control. The results of this study can provide scientific support for the precise control and treatment of heavy metal pollution in groundwater in Wuzhou City, Pearl River Delta, and at the same time offer an important reference for the formulation of drinking water safety guarantee strategies in similar urbanized areas.</div></div>","PeriodicalId":100480,"journal":{"name":"Environmental Chemistry and Ecotoxicology","volume":"8 ","pages":"Pages 392-407"},"PeriodicalIF":8.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145684255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tyre-derived ecotoxicity: Differentiating the effects from particles and chemical leachates on the blue mussel Mytilus edulis","authors":"M. Elisabetta Michelangeli ,&nbsp;Steven Brooks ,&nbsp;Sebastian Kuehr ,&nbsp;Emelie Forsman ,&nbsp;Elisabeth S. Rødland ,&nbsp;Sicco H. Brandsma ,&nbsp;Maria Margalef ,&nbsp;Manuel Heinzelmann ,&nbsp;Davide Spanu ,&nbsp;Jan Thomas Rundberget ,&nbsp;Tânia Gomes","doi":"10.1016/j.enceco.2026.01.003","DOIUrl":"10.1016/j.enceco.2026.01.003","url":null,"abstract":"<div><div>Tyre particles contain complex chemical additives that can leach out into the aquatic environment, posing potential risks to marine organisms. Despite growing evidence of adverse effects, the relative importance of particle-driven versus chemically mediated toxicity remains poorly explored, especially under environmentally relevant exposure scenarios. This study used the blue mussel (<em>Mytilus edulis</em>) as a model to differentiate these effects by exposing individuals to cryomilled tyre particles (TP), their leachates (L) and pre-leached particles (TPL) over 36 days at the environmentally relevant concentration of 0.1 g/L. Chemical analysis confirmed uptake of key organic additives such as poly(1,2-dihydro-2,2,4-trimethylquinoline) (TMQ), N-(1,3-dimethylbutyl)-<em>N</em>′-phenyl-<em>p</em>-phenylenediamine (6PPD), and 6PPD-quinone (6PPDQ), with certain compounds persisting after depuration. Particle-exposed mussels accumulated higher additive concentrations than those exposed to only leachates, indicating enhanced chemical release from particles. Biomarker responses revealed signs of oxidative stress and neurotoxicity in exposed mussels across all treatments, with earlier responses in leachate exposure and delayed responses during particle exposures. These results demonstrate that chemical additives are key toxicity drivers alongside physical particles, highlighting the importance of considering both pathways in environmental risk assessments. To our knowledge, this study is among the first to experimentally separate particle and leachate specific effects in mussels by using tyre particles before and after leaching to create contrasting chemical loads, thereby providing novel insights into their distinct and combined impacts on marine biota.</div></div>","PeriodicalId":100480,"journal":{"name":"Environmental Chemistry and Ecotoxicology","volume":"8 ","pages":"Pages 934-951"},"PeriodicalIF":8.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145977022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early-pregnancy exposure to persistent organic pollutants and bile acid alterations in relation to gestational glucose–lipid homeostasis","authors":"Sisi Wang ,&nbsp;Lan Chen ,&nbsp;Xiaopan Wu ,&nbsp;Yatao Wu ,&nbsp;Lei Zhang ,&nbsp;Xin Liu ,&nbsp;Yu Wang ,&nbsp;Jingguang Li ,&nbsp;Shen Wen ,&nbsp;Jing Huang ,&nbsp;Yongning Wu","doi":"10.1016/j.enceco.2025.12.028","DOIUrl":"10.1016/j.enceco.2025.12.028","url":null,"abstract":"<div><div>Persistent Organic Pollutants (POPs) are globally distributed, bioaccumulative chemicals that are increasingly implicated as environmental contributors to metabolic toxicity; however, the mechanistic pathways underlying their effects during early pregnancy remain poorly characterized. In this maternal cohort study, high-resolution mass spectrometry revealed that women with early metabolic abnormalities carried higher serum burdens of several POP congeners, with polybrominated diphenyl ethers (PBDEs; e.g., BDE-153, BDE-154) and polychlorinated biphenyl-52 (PCB-52) showing the most consistent elevations. Targeted metabolomics further identified marked alterations in bile acid profiles: putatively protective bile acids such as glycoursodeoxycholic acid (GUDCA) (2.32 vs. 2.79 ng/mL, <em>P</em> &lt; 0.05) and glycochenodeoxycholic acid (GCDCA) (2.32 vs. 4.77 ng/mL, <em>P</em> &lt; 0.05) were depleted in women with early metabolic abnormalities compared with those without, whereas taurine-conjugated species, including tauroursodeoxycholic acid (TUDCA), were elevated. Correlation analyses revealed inverse associations between brominated congeners and conjugated bile acids (e.g., BDE-154 with TUDCA, <em>r</em> = −0.29, <em>P</em> &lt; 0.001), whereas PCB-52 was positively associated with serum cholesterol levels. In mediation analyses, GUDCA and TUDCA jointly mediated up to 24 % of the association between PBDEs and dysregulated glucose metabolism, sulfated bile acids mediated 21–25 % of PBDE–triglyceride associations and norcholic acid (NorCA) accounted for 19 % of the PCB-52–cholesterol relationship. These findings provide human evidence that maternal POP exposure is associated with perturbations in bile acid metabolism that may contribute to impaired glucose–lipid homeostasis during early pregnancy, and highlight bile acids as mechanistic mediators and potential early biomarkers of pollutant-induced metabolic toxicity.</div></div>","PeriodicalId":100480,"journal":{"name":"Environmental Chemistry and Ecotoxicology","volume":"8 ","pages":"Pages 924-933"},"PeriodicalIF":8.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145977021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Haloacid dehalogenase–mediated dehalogenation and hydrolysis of oxadiazon and oxyfluorfen mitigate environmental risks in rice production","authors":"Yanan Qu ,&nbsp;Yizhuo Wang ,&nbsp;Siying Li ,&nbsp;Xuzhen Shi ,&nbsp;Gan Ai ,&nbsp;Xiaoliang Liu ,&nbsp;Zongzhe He ,&nbsp;Liqing Zeng ,&nbsp;Xuesheng Li ,&nbsp;Zhaojie Chen","doi":"10.1016/j.enceco.2025.10.027","DOIUrl":"10.1016/j.enceco.2025.10.027","url":null,"abstract":"<div><div>Protoporphyrinogen oxidase herbicides, such as oxadiazon (ODZ) and oxyfluorfen (OFF), were widely used to control field weeds for crop production. However, their excessive use can lead to its accumulation in soils and crops, affecting crop yields and human health. Therefore, developing a method to degrade ODZ and OFF in rice is crucial for ensuring food safety and agricultural productivity. A phase I reaction enzyme, haloacid dehalogenase-2 (HAD-2), has not been identified facilitates this breakdown. To assess the detoxifying and metabolic functions of HAD-2 on ODZ and OFF, we generated CRISPR-Cas9-based knockout mutant lines and genetically edited rice cultivars that overexpress <em>OsHAD-2</em> (OE). The metabolites and conjugates of these compounds were identified via high-performance liquid chromatography (HPLC) coupled to a linear ion trap (LTQ) tandem mass spectrometry (HPLC-LTQ-MS/MS). Our results indicated that the <em>OsHAD-2</em> was localized on the plasma membrane and significantly induced under ODZ/OFF stress. The overexpression of <em>OsHAD-2</em> conferred resistance to ODZ and OFF toxicity in rice compared with the wild-type (WT), as demonstrated by increased biomass and elongation of rice plants, reduced cellular damage, higher chlorophyll accumulation, and enhanced antioxidant and detoxification enzyme activities. The OE-16 rice seedlings removed 14 % and 32 % more ODZ/OFF from their growth medium, respectively, than the WT and accumulated considerably lower quantity of parent compounds. They also exhibited a greater abundance of degradative metabolites through dehalogenation and hydrolysis. The concentration of dechlorination-hydrolysis-oxadiazon (<em>m</em>/<em>z</em> 327) and hydrolysis-nitroreduction-oxyfluorfen (m/z 314) in the OE-16 rice grains were 2.13- and 2.70-fold higher than those in WT. In contrast, <em>OsHAD-2</em> knockout lines exhibited increased accumulation of toxic ODZ and OFF in rice, increased toxic symptoms under ODZ/OFF stress, and reduced growth performance. These rice seedlings also showed reduced levels of ODZ and OFF hydrolysis and dehalogenation metabolites, indicating a functional loss of <em>OsHAD-2</em>. These findings highlight the role of <em>OsHAD-2</em> expression in detoxifying protoporphyrinogen oxidase herbicides in rice, primarily through dehalogenation and hydrolysis mechanisms.</div></div>","PeriodicalId":100480,"journal":{"name":"Environmental Chemistry and Ecotoxicology","volume":"8 ","pages":"Pages 1-12"},"PeriodicalIF":8.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145521022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ecotoxicity of emerging pollutants: Interactive impact of polystyrene nanoplastics and Metanil yellow on Artemia salina","authors":"Mahalakshmi Kamalakannan,&nbsp;John Thomas","doi":"10.1016/j.enceco.2025.11.002","DOIUrl":"10.1016/j.enceco.2025.11.002","url":null,"abstract":"<div><div>Increasing concern surrounds the impact of pollutants on marine ecosystems, particularly the combined effects of nanoplastics and synthetic dyes. This present study evaluated the toxicity of 100 nm polystyrene nanoplastics (PSNPs) and Metanil Yellow (MY) co-exposure in <em>Artemia salina</em>, a model marine bioindicator. Physicochemical characterization through DLS, FTIR, and Raman analyses confirmed the interaction between PSNPs and MY, indicating dye adsorption on the surface of PSNPs and increased aggregate size after 48 h. The LC₅₀ value for the PSNPs+MY complex, 6.76 mg/L, was significantly lower than that of pristine 14.79 mg/L components, reflecting enhanced toxicity. Mortality rates exceeded 93 % in the complex-exposed group compared to 23 % and 66 % for PSNPs and MY alone, respectively. Co-exposure resulted in elevated ROS levels and enhanced antioxidant enzyme activity, indicating significant oxidative stress. The pristine treatment at 20 mg/L induced 73 % oxidative stress, while the complex exposure at 100 + 20 mg/L increased it to 86 %. Overall, the findings demonstrate that interactions between nanoplastics and dyes exacerbate toxic responses in marine organisms, posing a compounded ecological risk and highlighting the need for stricter monitoring and remediation of such emerging contaminants.</div></div>","PeriodicalId":100480,"journal":{"name":"Environmental Chemistry and Ecotoxicology","volume":"8 ","pages":"Pages 76-88"},"PeriodicalIF":8.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145521090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A review on occurrence characteristics and removal technologies of emerging contaminants in source-separated urine","authors":"Xiaoyong Wang ,&nbsp;Zhan Jin ,&nbsp;Shunfeng Jiang ,&nbsp;Ke Bei ,&nbsp;Min Zhao ,&nbsp;Zuxiang Li ,&nbsp;Xiangyong Zheng","doi":"10.1016/j.enceco.2026.01.024","DOIUrl":"10.1016/j.enceco.2026.01.024","url":null,"abstract":"<div><div>Source-separated urine is increasingly recognized as a promising resource for nutrient recovery; however, compared with conventional wastewater systems, the occurrence, behavior, and removal of emerging contaminants (ECs) in urine remain insufficiently characterized. Most existing urine-focused reviews primarily address nitrogen and phosphorus recovery or sanitation performance, while ECs are often only briefly discussed, resulting in fragmented evidence across contaminant classes and regions and limiting a coherent urine-centered understanding of exposure patterns and treatment needs.</div><div>This review synthesizes current knowledge on the occurrence and removal of ECs in source-separated urine, focusing on antibiotics, endocrine-disrupting chemicals, microplastics, and related persistent pollutants. By integrating bibliometric analysis with mechanistic evaluation of representative treatment technologies, we provide a structured overview of research trends, dominant contaminant groups, and key methodological limitations. Critical gaps are identified, including the scarcity of urine-specific datasets, inconsistencies in reported concentration metrics, and insufficient consideration of contaminant fate during urine treatment and resource recovery. The implications of these gaps for safe urine reuse are discussed, highlighting the need for targeted treatment strategies and standardized monitoring frameworks. Overall, this review offers a urine-centered perspective on ECs and provides guidance for advancing safe and sustainable urine resource recovery.</div></div>","PeriodicalId":100480,"journal":{"name":"Environmental Chemistry and Ecotoxicology","volume":"8 ","pages":"Pages 1122-1137"},"PeriodicalIF":8.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146077150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nutrient–warming synergy governs organophosphate esters bioavailability to dragonfly larvae","authors":"Haode He ,&nbsp;Mei Wang ,&nbsp;Wanru Zhang ,&nbsp;Yuhui Sun ,&nbsp;Hongyan Tian ,&nbsp;Chao Wei ,&nbsp;Haoyu Liu ,&nbsp;Yuxia Yang","doi":"10.1016/j.enceco.2026.01.016","DOIUrl":"10.1016/j.enceco.2026.01.016","url":null,"abstract":"<div><div>Accelerated global climate change has profoundly altered ecosystems and pollutant dynamics, severely hindering the accurate assessment of ecological risks associated with organophosphate esters (OPEs) due to the limitations of conventional monitoring approaches. To address these challenges, we developed an integrative “environment-biota-pollutant” framework, combining spatial statistics, machine learning, and structural equation modeling to elucidate OPE bioaccumulation in dragonfly larvae using a dataset comprising 6099 samples. The study reveals that dragonfly larvae exhibit pronounced spatial aggregation (Moran's <em>I</em> = 0.899–0.933) and exceptional bioconcentration capacity (mean log BAF = 3.63), surpassing traditional media. Through random forest modeling, nutrient salts (total phosphorus, total nitrogen, nitrate nitrogen) were identified as the primary drivers of OPE bioaccumulation in larvae, accounting for 25.22% of the variance, over three times greater than the contribution from direct aqueous OPE exposure (7.67%). Further analysis using partial least squares structural equation modeling demonstrated that warming enhances nitrate bioavailability (β = 0.742), which subsequently promotes OPE accumulation in larvae (β = 0.409). This finding indicates that climate-driven nutrient cycling is a more significant driver than aqueous OPEs concentration. As climate change continues to influence nutrient cycling and bioavailability, this integrative approach offers a robust framework for understanding and addressing the ecological risks associated with OPEs in an evolving environment.</div></div>","PeriodicalId":100480,"journal":{"name":"Environmental Chemistry and Ecotoxicology","volume":"8 ","pages":"Pages 1111-1121"},"PeriodicalIF":8.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146077142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Weathering-modulated gut-liver toxicity of tire wear particles in zebrafish: Source-specific effects and multi-omics insights","authors":"Xinrui Meng,&nbsp;Fan Wang,&nbsp;Qi Liang,&nbsp;Qingxuan Meng,&nbsp;Qianqian Song,&nbsp;Jing Cong","doi":"10.1016/j.enceco.2026.01.021","DOIUrl":"10.1016/j.enceco.2026.01.021","url":null,"abstract":"<div><div>Tire wear particles (TWPs) are pervasive microplastic pollutants whose hazard varies with environmental weathering and emission source. Here, we investigated how water leaching modifies the physicochemical properties of TWPs from heavy-duty (HTWPs) and light-duty (LTWPs) tires and assessed both particle-associated effects in adult zebrafish and leachate-mediated developmental toxicity in embryos (<em>Danio rerio</em>). Simulated leaching increased surface roughness and oxygenated functional groups and mobilized Zn, with stronger release from HTWPs. Under a phase-separation design in which leachates were removed, pristine particles induced more pronounced systemic toxicity in adult fish, including impaired growth and organ function, oxidative stress, gut dysbiosis, and activation of immune, apoptotic, and xenobiotic metabolism pathways, whereas leached particles showed attenuated particle-associated effects. Embryonic exposure to graded leachates caused concentration-dependent cardiotoxicity, delayed hatching, and developmental defects, with HTWP leachates more strongly disrupting mitochondrial function and phototransduction than LTWP leachates. Multi-omics analyses consistently indicated lower systemic stress in leached-particle groups yet persistent developmental hazards in the dissolved phase. Accordingly, environmental risk reflects the combined and context-dependent contributions of aged particles and their coexisting leachates, and remains strongly source-dependent (HTWPs &gt; LTWPs). These findings clarify how weathering redistributes, rather than simply reduces, TWP toxicity and should inform ecological risk assessment and management of non-exhaust vehicular emissions.</div></div>","PeriodicalId":100480,"journal":{"name":"Environmental Chemistry and Ecotoxicology","volume":"8 ","pages":"Pages 1057-1068"},"PeriodicalIF":8.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146077237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}