Environmental Chemistry and Ecotoxicology最新文献

{"title":"Fluorinated liquid crystal monomer (FLCM) induces kidney dysfunction by disrupting PPARα-mediated fatty acid oxidation: In vivo, in vitro, and in silico assays","authors":"Lin Peng ,&nbsp;Zenghua Qi ,&nbsp;Li Xiang ,&nbsp;Wei Wang ,&nbsp;Guodong Cao ,&nbsp;Yi Ru ,&nbsp;Xiaoxiao Wang ,&nbsp;Siyi Lin ,&nbsp;Zhu Yang ,&nbsp;Hong Yan ,&nbsp;Zongwei Cai","doi":"10.1016/j.enceco.2024.12.002","DOIUrl":"10.1016/j.enceco.2024.12.002","url":null,"abstract":"<div><div>Fluorinated liquid crystal monomers (FLCMs) are ubiquitous in our daily life as being the units of liquid crystal displays, yet their toxicological impacts remain largely unexplored. Herein, this study presents a comprehensive investigation into the hazardous effects of 3,4-difluoro-4′-(trans-4-ethylcyclohexyl)-biphenyl (DFECB), a representative biphenyl FLCM, using <em>in vivo</em>, <em>in vitro</em>, and <em>in silico</em> approaches. Mice exposed to human-relevant concentrations of DFECB for 30 days exhibited renal dysfunction, characterized by interstitial inflammation, glomerular morphological changes and metabolic disorders. Metabolomic profiling revealed inhibited fatty acid <em>β</em>-oxidation as a key factor in renal impairment, correlating with significant downregulation of peroxisome proliferator-activated receptor <em>α</em> (PPAR<em>α</em>). <em>In vitro</em> assays demonstrated DFECB-induced cytotoxicity, oxidative stress, inflammation and energy deficit in renal cells. Importantly, pretreatment with the PPAR<em>α</em> agonist mitigated the adverse effects of DFECB, underscoring the central role of PPAR<em>α</em> in DFECB-induced nephrotoxicity. Molecular docking simulations elucidated strong halogen and hydrophobic interactions between DFECB and PPAR<em>α</em>, providing mechanistic insights. Collectively, these results suggested that DFECB could act as a disruptor of the PPAR<em>α-</em>mediated fatty acid metabolism pathway, leading to renal dysfunction. This study highlights the potential health risks associated with FLCMs and emphasizes the need for their scientific regulation and further toxicological investigation.</div></div>","PeriodicalId":100480,"journal":{"name":"Environmental Chemistry and Ecotoxicology","volume":"7 ","pages":"Pages 192-200"},"PeriodicalIF":9.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143141200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High-resolution two-dimensional mapping of arsenic concentration in soil-water micro-interfaces with diffusive gradients in thin films","authors":"Xitong Li,&nbsp;Jiahui Zuo,&nbsp;Chuangchuang Zhang,&nbsp;Tieliang Zhang,&nbsp;Zeying He,&nbsp;Qiwen Zhou,&nbsp;Yujie Zhao,&nbsp;Wenjng Liu","doi":"10.1016/j.enceco.2024.12.006","DOIUrl":"10.1016/j.enceco.2024.12.006","url":null,"abstract":"<div><div>Arsenic (As) contamination in soils poses significant environmental and health risks, particularly in Asia. We present a new diffusive Gradients in thin-film (DGT) binding material (Bio-TiO₂) using microbial-assisted <em>in situ</em> precipitation, to determine the spatial distribution of As at submillimeter resolution. The Bio-TiO₂ gel exhibited superior homogeneity, smaller particle sizes, and higher adsorption capacity for As(V) (133.6 μg/cm²) and As(III) (55.2 μg/cm²) compared to most reported As binding gels. The DGT measurements provided high-resolution, two-dimensional mapping on As distribution in soil-water micro-interfaces process during soil flooding and drainage conditions, elucidating As dynamics with a sub-millimeter resolution (∼0.1 mm per pixel). This work presents an innovative and efficient method for As monitoring, providing significant implications for assessing As bioavailability and environmental risk.</div></div>","PeriodicalId":100480,"journal":{"name":"Environmental Chemistry and Ecotoxicology","volume":"7 ","pages":"Pages 211-220"},"PeriodicalIF":9.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143141257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rapid SERS detection of antimony using a superparamagnetic FA@MIL-101(Fe) composite substrate","authors":"Zhenli Sun ,&nbsp;Jianghong Tang ,&nbsp;Xunlong Ji ,&nbsp;Jingjing Du","doi":"10.1016/j.enceco.2024.12.007","DOIUrl":"10.1016/j.enceco.2024.12.007","url":null,"abstract":"<div><div>The pollution of antimony (Sb) and its accumulation as a persistent toxic substance (PTS) within environmental systems, leading to substantial hazards for ecosystems and public health. Therefore, developing rapid and sensitive methods for Sb detection is essential for mitigating its environmental impact. SERS presents a promising approach for detecting Sb, attributed to its high sensitivity and ability to capture distinct molecular fingerprints. However, traditional SERS substrates have struggled with effective detection because of weak interactions between Sb and traditional SERS substrate. To address this issue, a FA@MIL-101(Fe) composite combining Fe₃O₄’s magnetic properties and MIL-101(Fe)’s strong adsorption was synthesized, significantly enhancing Sb(III) detection. This substrate showed high sensitivity and selectivity, achieving a detection limit below 4 × 10⁻⁸ M, while effectively minimizing interference from other ions. Additionally, the substrate maintained long-term stability, consistently performing over 21 days. The FA@MIL-101(Fe) composite substrate offers a versatile and efficient platform for Sb(III) detection, providing broad potential for monitoring PTS in environmental applications.</div></div>","PeriodicalId":100480,"journal":{"name":"Environmental Chemistry and Ecotoxicology","volume":"7 ","pages":"Pages 221-228"},"PeriodicalIF":9.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143141261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ecotoxicological impacts of synthetic microfiber pollutants and development of sustainable mitigation strategies","authors":"Akankshya Das,&nbsp;Sudeshna Dey,&nbsp;Alok Prasad Das","doi":"10.1016/j.enceco.2024.12.003","DOIUrl":"10.1016/j.enceco.2024.12.003","url":null,"abstract":"<div><div>Microfibers are one of the most widespread, persistent, and increasingly common pollutants in wastewater accounting for 85 % of global shoreline pollution, and are found in 54 % of individual fish species. The current possible sources of this pollution are domestic laundering processes, commercial fishing activities, laundry discharge, and waste textiles relating to various anthropogenic activities. Approximately 90,000–380,000 tons of fiber have accumulated in the world's oceans. Microfiber pollution from textile manufacturing and everyday laundering processes releases up to 90 % of primary microfibers in the oceans. The consumption of synthetic microfibres by living organisms can disrupt feeding behaviors, impair growth, and compromise reproductive capabilities, ultimately resulting in effects at the population level. This paper focuses on improving the understanding of urban population influence on microfiber pollution and its fate and transport through various pathways into the environment. The review also emphasizes the ecotoxicological consequences of microfiber pollution on various living organisms and human health. Most significantly, the paper highlights novel strategies for sustainable microfiber waste management approaches.</div></div>","PeriodicalId":100480,"journal":{"name":"Environmental Chemistry and Ecotoxicology","volume":"7 ","pages":"Pages 201-210"},"PeriodicalIF":9.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143141260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nanoplastics in aquatic environments: The hidden impact of aging on fate and toxicity","authors":"Rega Permana ,&nbsp;Swaroop Chakraborty ,&nbsp;Eugenia Valsami-Jones","doi":"10.1016/j.enceco.2025.02.007","DOIUrl":"10.1016/j.enceco.2025.02.007","url":null,"abstract":"<div><div>The increasing release of plastic waste into aquatic ecosystems has led to the widespread occurrence of secondary microplastics (MPs) and nanoplastics (NPs), raising significant environmental and health concerns. While the toxicological effects of pristine NPs have been well documented, the role of aging—through processes such as ultraviolet (UV) photoaging and chemical oxidation—remains largely understudied. Aging fundamentally alters the physicochemical properties of NPs, potentially affecting their aggregation behaviour, eco-corona formation, and interactions with natural organic matter (NOM) and ions in aquatic environments. These changes may drastically shift the bioavailability and toxicity of NPs, making current assessments based on pristine particles environmentally unrealistic. This review synthesises the existing literature on NP aging, exploring how it affects their fate, transport, and toxicological impact on aquatic organisms. By identifying key knowledge gaps and highlighting the need for studies that account for environmental aging, this paper offers a roadmap for future research in NP environmental risk assessment. Understanding the dynamic transformations of NPs post-aging is crucial for developing more accurate models of their long-term ecological and human health impacts.</div></div>","PeriodicalId":100480,"journal":{"name":"Environmental Chemistry and Ecotoxicology","volume":"7 ","pages":"Pages 429-444"},"PeriodicalIF":9.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143437913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microplastics as persistent and vectors of other threats in the marine environment: Toxicological impacts, management and strategical roadmap to end plastic pollution","authors":"Sameh S. Ali ,&nbsp;Mohammed Hussein M. Alsharbaty ,&nbsp;Rania Al-Tohamy ,&nbsp;Michael Schagerl ,&nbsp;Majid Al-Zahrani ,&nbsp;Michael Kornaros ,&nbsp;Jianzhong Sun","doi":"10.1016/j.enceco.2024.12.005","DOIUrl":"10.1016/j.enceco.2024.12.005","url":null,"abstract":"<div><div>The myriad consumption of plastic regularly, environmental impact and health disquietude of humans are at high risk. Microplastics (MPs) represent a contemporary type of contamination that has permeated several environmental areas. MP pollution is already widespread in marine environments, leading to increased awareness over the past few decades. Multiple studies are being conducted to determine the source of MPs and their harmful impacts on marine life and, ultimately, human health. Thus, this paper rigorously analyzed the origin, accumulation, and detrimental impacts of MPs on the marine ecosystem. An increase in the death rate, a decrease in the rate of growth, and a reduction in the quantity of food ingested were the primary changes that occurred in marine organisms. The hydrophobic properties of MPs enable them to facilitate the formation of biofilms, which are referred to as the plastisphere. These biofilms have the capacity to transport chemicals that are frequently hazardous and may potentially infiltrate the food chain. The coronavirus 2019 (COVID-19) pandemic has significantly exacerbated the plastic and MP contamination in coastal and marine environments as a result of the improper management of personal protective equipment and explosive production. The most recent developments in environmental DNA (eDNA) are valuable tools for the detection and tracking of MP contamination in coastal and marine ecosystems. These technologies offer greater sensibility, efficacy, and involvement in the process. There are several measures and attempts that must be taken to address the MP pollution issues in the marine environment. The knowledge gained from this review will serve as a foundation for future marine MP research and management techniques.</div></div>","PeriodicalId":100480,"journal":{"name":"Environmental Chemistry and Ecotoxicology","volume":"7 ","pages":"Pages 229-251"},"PeriodicalIF":9.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143097923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fate of trace elements and emerging environmental pollutants (benzotriazoles and benzothiazoles) from a glacier-fed river in the mixing zone of an Arctic fjord system","authors":"Joséphine Amey ,&nbsp;Øyvind Mikkelsen","doi":"10.1016/j.enceco.2025.01.001","DOIUrl":"10.1016/j.enceco.2025.01.001","url":null,"abstract":"<div><div>The fate of organic and inorganic pollutants was studied in the Arctic, in the mixing zone of freshwater and seawater of a glacier-fed river and a fjord (Ny-Ålesund, Svalbard). Concentrations of trace elements and contaminants of emerging concern, benzotriazoles and benzothiazoles (BTRs and BTHs), were assessed. Metal concentrations of Al, As, Cr, Hg, Mo, Ni, Pb, Sb, Sn, V, and Zn in marine sediment were up to two or three times higher than in riverine sediment and most of them showed an increasing trend from the upper to the lower part of the river. Pb (0.058 μg/L) and Zn (0.80 μg/L) were present in levels of moderate pollution in seawater close to town, while Cu (0.11 μg/L) exceeded background levels in the same area. As (0.042 μg/L), Hg (0.004 μg/L) and Cd (0.011 μg/L) showed levels of low to moderate pollution in freshwater from the river. In seawater and river water detected BTRs and BTHs were: BTR, TTR, 2-OH-BTH, XTR, 2-Me-S-BTH, 2-M-BTH, 2-S-BTH, and 2-NH₂-BTH. Considerably high concentrations of BTR (1460 ng/L) and 2-OH-BTH (1070 ng/L) were found. Compounds present in marine and riverine sediment were BTR, 2-OH-BTH, 2-Me-S-BTH, and 2-M-BTH. Sediment appeared to be a significant sink of BTRs and BTHs with a concentration range of 1.13–32.7 ng/g. A trend of higher concentrations of trace elements in sediment (ANOVA, <em>p</em> = 0.044) and seawater (ANOVA, <em>p</em> = 0.013), as well as 2-OH-BTH in seawater (<em>t</em>-test, <em>p</em> = 0.010) was observed in the vicinity of the town, where most anthropogenic activities have taken place due to former mining operations.</div></div>","PeriodicalId":100480,"journal":{"name":"Environmental Chemistry and Ecotoxicology","volume":"7 ","pages":"Pages 339-350"},"PeriodicalIF":9.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143141254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Per- and polyfluorinated substances in reservoir water from a metropolitan city in the Guangdong-Hong Kong-Macao Greater Bay Area, China, and their ecological risks","authors":"Yiming Ge ,&nbsp;Yi Huang ,&nbsp;Linshen Xie ,&nbsp;Chenglin Li ,&nbsp;Xiujuan Qi ,&nbsp;Pu Ye ,&nbsp;Xixiang Guo ,&nbsp;Chen Deng ,&nbsp;Rong Hu ,&nbsp;Bei Wang ,&nbsp;Jinling Wang ,&nbsp;Yihong Liu ,&nbsp;Jiayi Xu ,&nbsp;Tingting Zhu ,&nbsp;Shaoyou Lu","doi":"10.1016/j.enceco.2025.01.009","DOIUrl":"10.1016/j.enceco.2025.01.009","url":null,"abstract":"<div><div><em>Per</em>- and polyfluorinated substances (PFASs) are synthetic chemicals with thermal and chemical stability, widely used in consumer products such as food packaging, fire-fighting foams, non-stick coatings, and lubricants. Their potential threats to human health and aquatic ecosystems have prompted restrictions on their usage. However, they are still widely found in freshwater systems due to their environmental persistence. Given that reservoirs are a vital source of drinking water for coastal city residents, this study collected water samples from 35 reservoirs in SZ City and its special cooperation zone to quantify 17 PFASs. Seasonal and spatial distributions of contaminant concentrations were analyzed and ecological risks were assessed. The results showed a widespread presence of PFASs in various reservoirs, although perfluoroalkane sulfonic acids (PFSAs) were infrequently detected. The concentration of ΣPFASs in the dry season (median: 20.5 ng/L) was significantly higher than that in the wet season (6.58 ng/L), likely attributable to a dilution effect after rainfall. Pentadecafluorooctanoic acid (median: 2.76 ng/L) and perfluoro-n-butanoic acid (3.90 ng/L) dominated in the wet and dry seasons, respectively. For spatial distribution, the ΣPFASs concentration in tributaries was markedly higher than that in reservoirs during the dry seasons (median: 58.1 ng/L vs. 20.5 ng/L), probably due to the diminished wet deposition of contaminants and the reduced mobility of tributary water flow. Furthermore, the concentration of short-chain PFASs was significantly greater than that of long-chain PFASs in the dry seasons (median: 16.0 ng/L vs. 3.10 ng/L), possibly related to the widespread application of short-chain compounds. Overall, the risk to the ecosystem and humans from PFASs in reservoirs is not significant. Future regulations on fluorochemical plants may be warranted to reduce the use and discharge of PFASs. Also, subsequent studies could include a wider range of samples to better estimate the potential risk posed by PFASs with varying chain lengths and functional groups to aquatic environment.</div></div>","PeriodicalId":100480,"journal":{"name":"Environmental Chemistry and Ecotoxicology","volume":"7 ","pages":"Pages 364-372"},"PeriodicalIF":9.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143141320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analytical and structural characterization of waste lithium-ion batteries for their effective recycling strategy","authors":"Sailaja Priyadarsini,&nbsp;Alok Prasad Das","doi":"10.1016/j.enceco.2024.12.004","DOIUrl":"10.1016/j.enceco.2024.12.004","url":null,"abstract":"<div><div>Lithium-ion batteries (LIBs) are crucial for energy storage but pose environmental and health risks due to toxic materials like lithium, cobalt, and nickel. Their rapid increase raises concerns about soil and water contamination from improper disposal, highlighting the need for effective recycling. Developing strategies requires understanding their chemical and structural composition, as well as assessing battery safety and integrity to minimize risks during processing. This study presents a comprehensive analytical and structural characterization of waste LIBs to apprise recycling processes using techniques including Scanning Electron Microscopy (SEM), X-ray Diffraction (XRD), Energy Dispersive X-ray (EDX), and Fourier Transform Infrared Spectroscopy (FTIR) to investigate the phase changes, material degradation, and chemical composition of the cathode, anode, electrolyte, and binder materials in spent LIBs. SEM micrographs and EDX mapping of LIB residues at 1000× and 1500× magnifications showed rough, spherical particles with a uniform size distribution of 10–12 μm. These particles, identified as metal and metal oxide components from the cathodes, play a key role in influencing microbial interactions and enhancing metal recovery efficiency during bioleaching. XRD patterns indicated the crystalline structures of LiCoO₂, with a dominant peak at 2θ = 26.39°. At the same time, Li (Ni Co Mn) O₂ exhibited distinct peaks at 2θ = 18.7°, 26.39°, 44.46°, and 66.18°, with some overlapping with LiCoO₂ at lower intensities. The FTIR spectrum provided insights into the chemical composition and molecular structures supporting the recycling of LIBs by offering critical information to improve material recovery, optimize processes, and enhance sustainability. This study underscores the importance of characterization in developing sustainable and cost-effective recycling strategies for LIBs.</div></div>","PeriodicalId":100480,"journal":{"name":"Environmental Chemistry and Ecotoxicology","volume":"7 ","pages":"Pages 182-191"},"PeriodicalIF":9.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143141259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Carbendazim led to neurological abnormalities by interfering metabolic profiles in zebrafish brain after short-term exposure","authors":"Tiancai Wang ,&nbsp;Zishuang Wang ,&nbsp;Guangqin Liao ,&nbsp;Xiabing Li ,&nbsp;Jingyi Gu ,&nbsp;Jing Qiu ,&nbsp;Yongzhong Qian","doi":"10.1016/j.enceco.2024.12.001","DOIUrl":"10.1016/j.enceco.2024.12.001","url":null,"abstract":"<div><div>Carbendazim is an agricultural fungicide and a widely present ecotoxic pollutant, but its damaging effects on the nervous system are not fully understood. Here, we assessed effects of short-term exposure to carbendazim on zebrafish brains. It has been revealed firstly that carbendazim can accumulate in the brain after a 7-day exposure, with the maximum concentration of 68.22 ± 9.84 μg/kg, which caused tissue vacuolization and neuronal damage, then led to a decline in motor behavioral abilities, especially a significant reduction in the distance moved. These changes may be attributed to metabolism abnormalities. Based on metabolomics and lipidomics, substantial alterations were observed in 264 lipids and 135 metabolites, with notable enrichment in 5 metabolic pathways, including glycerophospholipid metabolism, glycerolipid metabolism, and sphingolipid metabolism. To investigate system-level variations, weighted correlation network analysis was utilized to screen for 4 biomarkers strongly associated with carbendazim exposure: citric acid, guanosine-5′-monophosphate, sphingosine, and monoacylglycerol. The alterations of these markers confirmed damages of carbendazim to zebrafish nervous system, further elucidating that metabolic disorders caused by carbendazim in brains led to tissue damage and subsequent changes in motor behavior. This study provides scientific evidence for neurotoxicities of carbendazim and offers new insights into ecological risks.</div></div>","PeriodicalId":100480,"journal":{"name":"Environmental Chemistry and Ecotoxicology","volume":"7 ","pages":"Pages 164-173"},"PeriodicalIF":9.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143141256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}