Environmental Chemistry and Ecotoxicology最新文献

{"title":"Chemical leachates from car tyre granulates and PET bottles induce toxic effects on Mytilus edulis haemocytes","authors":"M. Elisabetta Michelangeli ,&nbsp;Sicco H. Brandsma ,&nbsp;Maria Margalef ,&nbsp;Emelie Forsman ,&nbsp;Sebastian Kuehr ,&nbsp;Davide Spanu ,&nbsp;Tânia Gomes","doi":"10.1016/j.enceco.2025.03.010","DOIUrl":"10.1016/j.enceco.2025.03.010","url":null,"abstract":"<div><div>Plastic materials contain hazardous chemicals, including additives like flame retardants, antioxidants, stabilizers, and metals, which can leach into the environment and impact aquatic life. This study is the first to evaluate the toxicity of leachates derived from car tyre granulates (CTG) and PET bottles (PET) on haemocytes of the mussel <em>Mytilus edulis</em> using a flow cytometry approach close to in vitro conditions. Following 24 h exposure, CTG leachates, characterized by a complex chemical profile (13,520 features) and high metal load, reduced cell viability, metabolic activity, mitochondrial reactive oxygen species (ROS) formation, lipid peroxidation (LPO) and lysosomal content. These leachates also impaired cytoplasmatic and mitochondrial membrane potentials, increased neutral lipids and altered DNA content. PET leachates, although with fewer chemical features (5631) and metal levels, also reduced cell viability, metabolic activity, LPO, and lysosome content, while increasing cytoplasmic membrane potential, ROS levels, NL, and altering MMP and DNA content. These findings indicated that leachates from CTG and PET can impair haemocytes functions in bivalves through mechanisms such as oxidative stress, membrane depolarization, and disrupted metabolic processes, underscoring their toxic potential. This study highlighted the toxicity pathways of plastic leachates in marine organisms, linking their complex chemical composition of organic and inorganic compounds to high ecotoxicological risks in environmental conditions.</div></div>","PeriodicalId":100480,"journal":{"name":"Environmental Chemistry and Ecotoxicology","volume":"7 ","pages":"Pages 776-790"},"PeriodicalIF":9.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143843559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Weakened serum albumin binding-to-activated EGFR internalization in cellular accumulation for the synergistic toxicity of tetrabromobisphenol A and perfluorooctanoic acid","authors":"Chuxuan Chen ,&nbsp;Xijuan Chao ,&nbsp;Mingjiang Zuo ,&nbsp;Guoqiang Shan ,&nbsp;Yongmei Qi ,&nbsp;Dejun Huang ,&nbsp;Zhiguo Sheng ,&nbsp;Benzhan Zhu","doi":"10.1016/j.enceco.2025.03.004","DOIUrl":"10.1016/j.enceco.2025.03.004","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Background&lt;/h3&gt;&lt;div&gt;Brominated flame retardants (BFRs) and per-fluoroalkyl substances (PFAS), are globally concerned persistent toxic substances (PTS) with high co-exposure risks due to their coexistence in the environment matrices and even in humans. However, their combined toxicity hasn't been explored yet. The respective representatives tetrabromobisphenol A (TBBPA) and perfluorooctanoic acid (PFOA) share similar exposure routes and properties of substantial bioaccumulation and environmental persistence.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Objectives&lt;/h3&gt;&lt;div&gt;To investigate the combined toxicity of BFRs and PFAS with TBBPA and PFOA as the research subjects, and elucidate the mechanisms responsible for the combined toxicity.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methods&lt;/h3&gt;&lt;div&gt;Combined toxicity were evaluated after co-exposure with TBBPA and PFOA at non-toxic and even environmentally relevant low doses in vitro. Cellular accumulation of TBBPA/PFOA was detected by UPLC-MS/MS. Serum albumin binding constant of TBBPA or PFOA under single and co-existence was detected by fluorescence spectrometric titration, and the effects of varied albumin binding affinity on cellular accumulation were evaluated. Then, combined methods of transcriptomics, Q-PCR, Western blot, immunofluorescence imaging, gene knockdown and molecular docking were employed to detect epidermal growth factor receptor (EGFR) expression, internalization and its role in contributing to the cellular uptake of the pollutants.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;div&gt;Cell viability under co-exposure with 100 μM TBBPA/250 μM PFOA at non-toxic concentration alone reduced to 65.55 %, while the ratio of apoptotic and necrotic cells enhanced to 63.93 %. The combined toxicity was demonstrated to be synergism. Increased cellular accumulation of each pollutant was responsible for the synergistic toxicity. We next found TBBPA/PFOA co-existence can weaken each other's serum albumin binding ability, leading to higher free TBBPA and PFOA levels in medium that were easier for cellular uptake than albumin-bounded ones, thereby resulting in the enhanced cellular levels of both compounds. Endocytosis was then demonstrated to contribute to the cellular uptake of free TBBPA/PFOA molecules. Thereafter, a non-canonical EGFR internalization was activated and upregulated due to the cellular oxidative stress, which further mediated more cellular uptake of TBBPA/PFOA.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Conclusion&lt;/h3&gt;&lt;div&gt;Taken together, the effects of weakened serum albumin binding-to-activated EGFR internalization contributed to the enhanced cellular accumulation of each pollutant in a cascade mode, thereby resulting in the combined cytotoxicity. Our findings represent the first experimental study on BFRs and PFAS co-exposure risks with TBBPA/PFOA, and propose a new mechanism for the combined toxicity, which may have broad environmental, chemical, and biomedical significance for future research on the other environmental pollutants and their analogs.&lt;/d","PeriodicalId":100480,"journal":{"name":"Environmental Chemistry and Ecotoxicology","volume":"7 ","pages":"Pages 623-634"},"PeriodicalIF":9.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143714663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synergistic effect of arsenate and microplastics and its toxicity mechanism on lettuce","authors":"Li Mu ,&nbsp;Mengyuan Wang ,&nbsp;Xin Tang ,&nbsp;Jishi Wang ,&nbsp;Jiandong Sheng ,&nbsp;Yi Peng ,&nbsp;Ziwei Gao","doi":"10.1016/j.enceco.2025.04.009","DOIUrl":"10.1016/j.enceco.2025.04.009","url":null,"abstract":"<div><div>Arsenate (As(V)) and polystyrene microplastics (PS MPs) in irrigation water have become significant environmental concerns. This study investigates the combined effects of PS MPs and As(V) and its toxicity mechanism on lettuce (<em>Lactuca sativa</em>). The adsorption experiments showed that As(V) was adsorbed by PS MPs, which enhanced its uptake by lettuce. The adsorption capacity decreased by 4.6 % as the temperature increased from 15 °C to 35 °C, with the highest adsorption occurring at 15 °C. X-ray photoelectron spectroscopy (XPS) analysis revealed reduced binding energy of carboxyl (-COOH) groups on PS MP surfaces after As(V) adsorption, indicating that carboxyl groups are key sites for As(V) binding and accumulation. In the V1P30 and V10P30 treatment groups, co-exposure to As(V) and PS MPs significantly reduced lettuce root length (by 42.8 %) and leaf weight (by 56.2 %) compared to the V1 and V10 groups exposed to As(V) alone. Catalase (CAT) activity in the V10P30 group increased by 203.7 %, reflecting a marked increase in oxidative stress due to the combined exposure. Nutrient analysis showed that As(V) exposure in the V10 group increased magnesium (Mg) content by 50 % and calcium (Ca) content by 240 %. In contrast, in the V1P10 group, potassium (K) content increased by 65 %, while iron (Fe) content decreased by 58.8 %, indicating a significant nutrient imbalance caused by the presence of PS MPs. Nitrite content in the V10P10 group increased by 1.52 times, while soluble protein and vitamin C contents decreased by 36.2 % and 24.3 %, respectively, pointing to a reduction in the plant's nutritional quality due to co-exposure. Metabolomic analysis revealed that co-exposure to As(V) and PS MPs enhanced glutathione (GSH) synthesis and improved membrane stability by upregulating metabolites involved in antioxidant defense and osmotic regulation. This study demonstrates that PS MPs enhance the toxicity of As(V) in lettuce by facilitating its uptake and disrupting nutrient balance, leading to increased oxidative stress and alterations in metabolic pathways. These findings provide new insights into the environmental risks of contaminated systems and offer implications for future pollution management strategies.</div></div>","PeriodicalId":100480,"journal":{"name":"Environmental Chemistry and Ecotoxicology","volume":"7 ","pages":"Pages 924-934"},"PeriodicalIF":9.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143947710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A comprehensive analytical approach to monitoring selected emerging contaminant classes in sewage sludge and e-waste from Norway","authors":"Daniel Gutiérrez-Martín ,&nbsp;Gabriela Castro ,&nbsp;Susana V. González ,&nbsp;Hans Peter H. Arp ,&nbsp;Rebeca López-Serna ,&nbsp;Alexandros G. Asimakopoulos","doi":"10.1016/j.enceco.2025.05.004","DOIUrl":"10.1016/j.enceco.2025.05.004","url":null,"abstract":"<div><div>Sewage sludge and waste from electrical and electronic equipment (WEEE) constitute the most challenging materials to manage within a circular economy framework due to their complex composition and the presence of hazardous substances. Their increasing generation results in a wide variety of contaminants, highlighting the need for new strategies to ensure their proper management. Herein, an analytical procedure was developed for the analysis of 75 contaminants belonging to 7 contaminant classes in sewage sludge and WEEE: benzothiazoles, benzotriazoles, poly- and perfluorinated alkyl substances (PFAS), bisphenols, benzophenones, parabens, and monoester phthalate analogues and phthalic acid (mPHTs). The proposed methodology involved liquid-solid extraction (LSE) assisted by ultrasonication, followed by solid phase extraction (SPE) as a clean-up step, tailored to liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). The methodology was successfully applied, obtaining method limits of quantification (mLOQs) ranging from 0.06 to 21.7 ng g⁻¹ in WEEE and from 0.26 to 43.6 ng g⁻¹ d.w. in sewage sludge. Median total concentrations of the target contaminants ranged from 22.5 to 257 ng g⁻¹ d.w. in sludge, and from 3.50 to 1025 ng g⁻¹ in WEEE. Removal efficiencies during the treatment of sludge were also assessed, demonstrating 89 % removal of the total concentrations during anaerobic digestion of sludge. Regarding WEEE, mPHTs demonstrated the highest detection rates, while PFAS were the least detected. This work improves the understanding of environmental contamination caused by emerging contaminants present in both sludge and WEEE and emphasizes the critical need for effective management.</div></div>","PeriodicalId":100480,"journal":{"name":"Environmental Chemistry and Ecotoxicology","volume":"7 ","pages":"Pages 901-909"},"PeriodicalIF":9.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143941809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"BiOI-embedded molecularly imprinted polymer-functionalized BiOIO3 photocatalyst with spatially coupled dual-active sites for efficient selective citalopram removal","authors":"Lin Liu,&nbsp;Runan Chen,&nbsp;Chenshi Luo,&nbsp;Pengfei Liang,&nbsp;Mengyuan Zhang,&nbsp;Yongli Liu,&nbsp;Guifen Zhu","doi":"10.1016/j.enceco.2025.05.011","DOIUrl":"10.1016/j.enceco.2025.05.011","url":null,"abstract":"<div><div>Achieving high-selectivity priority identification and degradation of target pollutants in complex water environments using photocatalytic technology remain challenging. Herein, we proposed a novel strategy for the simultaneous formation of BiOI and imprinting polymers on the BiOIO₃ substrate to obtain a molecularly imprinted photocatalyst (EMI-Bi/Bi4) capable of highly selective adsorption and degradation of citalopram (CIT) in complex media. The prepared EMI-Bi/Bi4 exhibited excellent selective recognition ability toward the template molecule CIT, with a theoretical maximum adsorption capacity of 343.68 mg g⁻¹ and an imprinting factor of 7.2. In the coexisting system of CIT and CBZ, the adsorption selectivity coefficient (K) of EMI-Bi/Bi4 was as high as 26.936, and the degradation selectivity factor (α) exceeds 3.12. Under a wide pH range (3−11) and presence of humic acid, the CIT removal efficiency of EMI-Bi/Bi4 exceeded 93%. Even after seven consecutive cycles, the CIT removal efficiency remained above 84%. Precise imprinting site identification and effective photoactive species utilization enabled highly selective CIT removal in urban wastewater, achieving ≥ 90.3%, which was 17% higher than that of traditional surface-imprinted photocatalysts. DFT simulations and microstructure characterization confirmed that the highly selective CIT removal by EMI-Bi/Bi4 is due to hydrogen bonds, van der Waals forces, and electrostatic interactions between CIT and functional monomers; as well as the imprinted cavities highly matching the spatial structure of CIT and the highly overlapping imprinted sites and degradation sites formed by BiOI embedding in the imprinted polymer. This strategy enhances the concept of the highly selective identification and efficient photocatalytic degradation of targets in actual water.</div></div>","PeriodicalId":100480,"journal":{"name":"Environmental Chemistry and Ecotoxicology","volume":"7 ","pages":"Pages 953-965"},"PeriodicalIF":9.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144105465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unmasking microplastics in anaerobic digestion: Hidden threats, synergistic pollutants, and biodegradation Frontiers — A comprehensive hotspot review","authors":"Sameh S. Ali ,&nbsp;Rania Al-Tohamy ,&nbsp;Jianzhong Sun","doi":"10.1016/j.enceco.2025.05.008","DOIUrl":"10.1016/j.enceco.2025.05.008","url":null,"abstract":"<div><div>Microplastics (MPs) are emerging as silent disruptors in anaerobic digestion (AD) systems—critical infrastructure in the global push toward sustainable waste-to-energy conversion. While AD has long been championed for its role in renewable energy generation and waste minimization, the infiltration of MPs introduces a complex, largely uncharted set of biochemical and ecological challenges. This review unpacks the novel intersection of MP pollution and AD performance, shedding light on how these persistent particles disrupt microbial pathways, suppress methane yield, and act as vectors for hazardous pollutants like antibiotics, heavy metals, and persistent organic pollutants. Integrating cutting-edge bioremediation strategies and bibliometric insights, this work positions MPs not just as an environmental nuisance but as a biochemical bottleneck in circular economy systems. Understanding and mitigating MP impacts in AD is no longer optional—it's the key to unlocking the next generation of resilient, high-performance bioenergy platforms.</div></div>","PeriodicalId":100480,"journal":{"name":"Environmental Chemistry and Ecotoxicology","volume":"7 ","pages":"Pages 980-1010"},"PeriodicalIF":9.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144105597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of organophosphate and pyrethroid pesticide metabolites and phenoxyacid herbicides with blood pressure and hypertension among older adults","authors":"Qinxin Huang ,&nbsp;Shaofang Song ,&nbsp;Fenfang Deng ,&nbsp;Jia He ,&nbsp;Jun Yuan ,&nbsp;Lei Tan","doi":"10.1016/j.enceco.2025.05.017","DOIUrl":"10.1016/j.enceco.2025.05.017","url":null,"abstract":"<div><div>Previous studies suggest an association between pesticide exposure and elevated blood pressure, but have focused on occupationally exposed populations or the general population. Older adults represent a vulnerable population with potentially heightened susceptibility to pesticide exposure and more complex health management requirements due to age-related physiological changes. In this study, we investigated the association of organophosphate and pyrethroid pesticide metabolites and phenoxyacid herbicides with blood pressure and hypertension in 360 older adults from the Guangzhou community-based health management services program. A significant positive association was observed between ln para-nitrophenol and hypertension (odds ratio: 1.08, 95 % CI: 1.02–1.48, <em>P</em> = 0.03) after false discovery rate correction. We observed sex-specific associations of pesticide metabolites with hypertension and blood pressure. Specifically, sex-stratified logistic models indicated that 2,4-dichlorophenoxyacetic acid was associated with higher hypertension risk in males. Restricted cubic spline analyses demonstrated stronger and non-linear patterns of associations of 3-phenoxybenzoic acid and <em>trans</em>-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropane carboxylic acid with hypertension risk in females, while these associations in males were weak or non-significant. Bayesian Kernel Machine Regression revealed significant positive joint effects of pesticide metabolites on hypertension and systolic blood pressure. Para-nitrophenol and 2,4-dichlorophenoxyacetic acid were identified as the most significant pesticide metabolites that contributed to elevated hypertension risk and systolic blood pressure, respectively. Sex-stratified analyses confirmed the presence of joint effects of pesticide metabolites on hypertension in both males and females, with substantially stronger associations observed among females. The study demonstrated the associations of pesticide exposure with hypertension and blood pressure in older adults, suggesting that routine pesticide biomonitoring should be implemented to identify this potentially overlooked risk factor for more comprehensive cardiovascular health risk assessment.</div></div>","PeriodicalId":100480,"journal":{"name":"Environmental Chemistry and Ecotoxicology","volume":"7 ","pages":"Pages 1027-1036"},"PeriodicalIF":9.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144137878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dermal bioaccessibility and health risk assessment associated with mining production of metals (Pb-Zn-Ag) and critical raw materials (Sb-W) in the Iberian Peninsula","authors":"Inmaculada Ferri-Moreno ,&nbsp;Iker Martínez-del-Pozo ,&nbsp;Pablo Huertas ,&nbsp;Pablo Higueras ,&nbsp;José Ignacio Barquero-Peralbo ,&nbsp;José María Esbrí ,&nbsp;Mari Luz García-Lorenzo","doi":"10.1016/j.enceco.2025.02.011","DOIUrl":"10.1016/j.enceco.2025.02.011","url":null,"abstract":"<div><div>The exploitation of crucial materials for economic development, and exposure to waste enriched with potentially toxic elements (PTEs) has recently increased, requiring risk assessment to protect the health of workers. In this work, residua from two derelict mines have been studied to determine the health risks associated with direct dermal contact. Using <em>in vitro</em> tests with synthetic sweat (EN 1811 and NIHS 96–10) to simulate PTE bioaccessibility for children (2-h exposure) and adults (8-h exposure). The results showed that the more acidic sweat (NIHS 96–10) yielded higher levels of PTEs. Tailings and dumps had higher bioaccessibility than soils, with Pb and Zn being the most extracted PTEs and As and Sb had low mobility. Higher bioaccessibility levels were observed after 2 h of exposure, highlighting greater risks for children due to their greater vulnerability. Cadmium levels were sufficient to cause non-carcinogenic effects, whereas Pb and As posed carcinogenic risks. Although bioaccessibility data do not imply bioavailability of the element, as some species have been reported to be unable to cross the skin, penetration of PTEs through existing lesions may occur. Methodologies used to obtain Dermal Average Dose (DAD) showed that the use of generic parameters and the exclusion of bioaccessibility data underestimates results for non-carcinogenic assessment. For carcinogenic effects, results from both methods were similar. This validates the soil-skin approach as an efficient and cost-effective tool for health risk assessment.</div></div>","PeriodicalId":100480,"journal":{"name":"Environmental Chemistry and Ecotoxicology","volume":"7 ","pages":"Pages 506-515"},"PeriodicalIF":9.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143511823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antibiotics in water: Bean pods as adsorbent for removing and recovering ciprofloxacin","authors":"Jennifer Gubitosa ,&nbsp;Domenico Cignolo ,&nbsp;Vito Rizzi ,&nbsp;Luca Pace ,&nbsp;Paola Fini ,&nbsp;Andrea Petrella ,&nbsp;Chiara Milanese ,&nbsp;Sara Paraboschi ,&nbsp;Pinalysa Cosma","doi":"10.1016/j.enceco.2025.04.007","DOIUrl":"10.1016/j.enceco.2025.04.007","url":null,"abstract":"<div><div>During this work, the Bean Pods are reported as adsorbent to remove Contaminants of Emerging Concern from water. Specifically, the Bean Pods were washed before their use with 1 M NaOH and HCl solutions, for activating their surface and rendering the material porous with a larger surface area, as evidenced by BET and SEM analyses. Indeed, the pods were fully characterized by adopting different techniques, and UV–Vis spectroscopy was adopted to monitor, at several contact times, contaminated water. To pursue this aim, Ciprofloxacin, a largely used antibiotic, was selected as a model contaminant, exhibiting an high absorption in the UV–Vis spectrum. Moreover, the roles of the physical and chemical parameters such as ionic strength, pH, adsorbent/pollutant amounts, and temperature, during the adsorption, were assessed, obtaining interesting information on the whole process, that occurred efficiently with a maximum adsorption capacity of 45 mg/g. The increase of the adsorbent amount (from 3 to 25 mg) and decrease of pollutant concentration (from 30 to 10 mg/L) favored the Ciprofloxacin removal due to the large presence of active sites. The change of pH values (i.e. 3, 6 and 12) and ionic strength values (in the range 0.001–0.5 M by adopting NaCl) largely inhibited the adsorption, evidencing the presence of electrostatic interactions. The adsorption isotherms, thermodynamics and kinetics of the process were also studied. Specifically, the Freundlich and Temkin models well described the process, suggesting the heterogeneous character of the adsorption, with the formation of a pollutant multilayer onto the adsorbent surface; the process occurred spontaneously (ΔG &lt; 0) with an increase of entropy (ΔS &gt; 0), and it was favored by the increase of temperature (ΔH &gt; 0). The pseudo-first-order kinetic equation described the process with the applicability of the Weber-Morris model, denoting the key role of active sites to host the pollutant, and intraparticle diffusion, respectively. The recycling of the proposed adsorbent was successfully demonstrated by means of a salt solution. New horizons in the use of Bean Pods, for water remediation, was thus successfully demonstrated during this work, proposing an environmentally friendly approach for decontaminating water.</div></div>","PeriodicalId":100480,"journal":{"name":"Environmental Chemistry and Ecotoxicology","volume":"7 ","pages":"Pages 762-775"},"PeriodicalIF":9.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143843558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evidence linking phthalate exposure to alterations of hematologic parameters in Chinese children: A cross-sectional study","authors":"Mei-Ting Wei ,&nbsp;Ying Wen ,&nbsp;Zhu-Xia Zhang ,&nbsp;Xiu-Ju Liu ,&nbsp;Feng-Xiang Wei ,&nbsp;Wei-Qiang Liu ,&nbsp;Li Zhou ,&nbsp;Ding-Yan Chen ,&nbsp;Yao Yao","doi":"10.1016/j.enceco.2025.01.008","DOIUrl":"10.1016/j.enceco.2025.01.008","url":null,"abstract":"<div><div>School-aged children are a particularly susceptible population to phthalate exposure, yet research examining the correlation between combined exposure to multiple phthalates and hematologic changes is limited. We explored the individual and joint associations of early childhood phthalate exposure with hematologic parameters. A total of 1053 school-aged children from Shenzhen, China, 6–8 years of age, were enrolled in this cross-sectional study. Nine phthalate metabolites (mPAEs) and four hematologic parameters (white blood cell [WBC] count, red blood cell [RBC] count, hemoglobin [Hb], and platelet [PLT] count) were measured at the same time. To evaluate the connections between mPAEs and hematologic indices, both individually and in combination, several analytical approaches were used, including the generalized linear model (GLM), the Bayesian kernel machine regression (BKMR) model, and the quantile g-computation (QGC) model. The findings of the GLM indicated that the majority of mPAEs were correlated with hematologic parameters. Specifically, higher levels of mono-(2-ethyl-5-oxohexyl) phthalate [MEOHP] (<em>β</em>: –0.021; 95 % CI: −0.029, −0.012) and mono-(2-ethylhexyl) phthalate [MEHP] (<em>β</em>: –0.022; 95 % CI: −0.036, −0.008) were associated with a decreased PLT count. The results of the QGC and BKMR models showed that the mPAE mixture had a negative correlation trend with the PLT count (<em>β</em> = −0.023; <em>P</em> = 0.034). There was also a weak downward trend with the WBC count, RBC count, and Hb concentration. It is worth noting that among the mixed effects, MEOHP and MEHP had the greatest impact on the four hematologic parameters and showed a consistent negative correlation. Our study demonstrated that mPAEs are closely associated with hematologic parameters in school-aged children, especially the PLT count, and identified MEOHP and MEHP as the key contributors to the joint effect. These findings demonstrate the importance of reducing the potential health hazards of phthalate exposure to the hematologic system in children.</div></div>","PeriodicalId":100480,"journal":{"name":"Environmental Chemistry and Ecotoxicology","volume":"7 ","pages":"Pages 373-380"},"PeriodicalIF":9.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143377256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}