{"title":"Actualités en endocrinologie thyroïdienne","authors":"P. Rodien, A. Bourdelot, F. Savagner","doi":"10.1016/J.EMCEND.2004.10.001","DOIUrl":"https://doi.org/10.1016/J.EMCEND.2004.10.001","url":null,"abstract":"","PeriodicalId":100422,"journal":{"name":"EMC - Endocrinologie","volume":"1 1","pages":"39-49"},"PeriodicalIF":0.0,"publicationDate":"2005-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89267557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Actualits sur la mnopause. Donnes de la mdecine factuelle ( evidence based medecine )","authors":"H. Rozenbaum","doi":"10.1016/J.EMCEND.2004.09.002","DOIUrl":"https://doi.org/10.1016/J.EMCEND.2004.09.002","url":null,"abstract":"","PeriodicalId":100422,"journal":{"name":"EMC - Endocrinologie","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2005-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89370042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Leenhardt, F. Menegaux, B. Franc, C. Hoang, S. Salem, M. Bernier, L. Dupasquier-Fediaevsky, E. Le Marois, A. Rouxel, J. Chigot, L. Chérié-Challine, A. Aurengo
{"title":"Cancers de la thyroïde","authors":"L. Leenhardt, F. Menegaux, B. Franc, C. Hoang, S. Salem, M. Bernier, L. Dupasquier-Fediaevsky, E. Le Marois, A. Rouxel, J. Chigot, L. Chérié-Challine, A. Aurengo","doi":"10.1016/J.EMCEND.2004.10.003","DOIUrl":"https://doi.org/10.1016/J.EMCEND.2004.10.003","url":null,"abstract":"","PeriodicalId":100422,"journal":{"name":"EMC - Endocrinologie","volume":"95 1","pages":"1-38"},"PeriodicalIF":0.0,"publicationDate":"2005-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74969112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Physiologie de la prolactine","authors":"P. Touraine , V. Goffin","doi":"10.1016/j.emcend.2004.10.002","DOIUrl":"https://doi.org/10.1016/j.emcend.2004.10.002","url":null,"abstract":"<div><p>Prolactin, the lactation hormone, has multiple biological and physiological functions, which are most often poorly understood. However, as a result of the identification of the various isoforms of its receptor, our knowledge about this hormone and its actions has been largely improved. Moreover, the fact that models of knockout animals for PRL or PRLR genes have been made available has enabled to identify new target tissues for physiological actions of this hormone.</p></div>","PeriodicalId":100422,"journal":{"name":"EMC - Endocrinologie","volume":"2 1","pages":"Pages 50-76"},"PeriodicalIF":0.0,"publicationDate":"2005-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.emcend.2004.10.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90028089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. Rodien (Praticien hospitalier) , A. Bourdelot (Praticien hospitalier attaché) , F. Savagner (Maître de conférence, praticien hospitalier)
{"title":"Actualités en endocrinologie thyroïdienne","authors":"P. Rodien (Praticien hospitalier) , A. Bourdelot (Praticien hospitalier attaché) , F. Savagner (Maître de conférence, praticien hospitalier)","doi":"10.1016/j.emcend.2004.10.001","DOIUrl":"https://doi.org/10.1016/j.emcend.2004.10.001","url":null,"abstract":"<div><p>These last years, significant changes have occurred in thyroid endocrinology, as a consequence of the generalized use of molecular biology techniques. New genes have been identified, which are involved in congenital hypothyroidism, in the development of thyroid cancer, and in the action of thyroid hormones. Clinical consequences remain sometimes speculative, but in some cases such as in the management of thyroid cancer, therapeutic strategies already evolve. Whereas some retinoic acid derivatives can cause central hypothyroidism, others are used to re-differentiate those thyroid cancers which have lost the ability to concentrate iodide. New syndromes have been described and their molecular cause elucidated. Consumption hypothyroidism is due to the ectopic expression of deiodinase type 3, a severe mental retardation related to the chromosome X which is due to abnormal transport of T3. Several syndrome associations including congenital hypothyroidism have been identified, as well as the Pendred syndrome. Finally, new molecules such as the agonists of thyroid hormone receptors that have been studied in the animal should demonstrate beneficial effects in the management of obesity and dyslipemias.</p></div>","PeriodicalId":100422,"journal":{"name":"EMC - Endocrinologie","volume":"2 1","pages":"Pages 39-49"},"PeriodicalIF":0.0,"publicationDate":"2005-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.emcend.2004.10.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91724324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Calcitonine et peptides apparentés","authors":"R. Cohen , K.L. Becker , A. Jullienne","doi":"10.1016/j.emcend.2004.07.001","DOIUrl":"10.1016/j.emcend.2004.07.001","url":null,"abstract":"<div><p>Mature calcitonin is a 32 amino acid peptide. It is the main peptide of a wide peptide family, i.e., CT gene-related peptides I and II (CGRP-I and II), adrenomedullin, amylin. These peptides have similar structures and actions on 7 transmembrane receptors. The higher levels of CT are found in thyroids. Despite more than 40 years of study the definitive physiologic role of CT remains unknown. Total thyroidectomy or gene invalidation in mouse models does not modify physiologic parameters. Nevertheless CT levels determination is of value for clinicians as a sensitive and specific marker of medullary thyroid carcinoma. In sepsis, procalcitonin has also a diagnostic and prognostic value. Moreover, in septic conditions, CT immmuno-neutralization is able to improve the prognosis as shown in animal models.</p></div>","PeriodicalId":100422,"journal":{"name":"EMC - Endocrinologie","volume":"1 4","pages":"Pages 200-213"},"PeriodicalIF":0.0,"publicationDate":"2004-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.emcend.2004.07.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90951320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Un nouveau mécanisme et peut-être un traitement inattendu pour certains diabètes du nouveau-né","authors":"M.-L. Raffin-Sanson","doi":"10.1016/j.emcend.2004.08.001","DOIUrl":"10.1016/j.emcend.2004.08.001","url":null,"abstract":"","PeriodicalId":100422,"journal":{"name":"EMC - Endocrinologie","volume":"1 4","pages":"Pages 214-216"},"PeriodicalIF":0.0,"publicationDate":"2004-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.emcend.2004.08.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73521944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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