EFSA Supporting Publications最新文献

{"title":"Preparatory work for the evaluation of the safety of preparations from the fruits of sweet and bitter fennel (Foeniculum vulgare Mill. and Foeniculum piperitum (Ucria) C.Presl)","authors":"Alessandra Tata,&nbsp;Filippo Marzoli,&nbsp;Honoria Ocagli,&nbsp;Ileana Baldi,&nbsp;Dario Gregori,&nbsp;Simone Belluco","doi":"10.2903/sp.efsa.2025.EN-9589","DOIUrl":"https://doi.org/10.2903/sp.efsa.2025.EN-9589","url":null,"abstract":"<p>This report is the outcome of an EFSA procurement (OC/EFSA/MESE/2022/03 – SC11) reviewing relevant scientific information related to the evaluation of the safety in use of preparations from the fruits of sweet and bitter fennel (<i>Foeniculum vulgare</i> Mill. and <i>Foeniculum piperitum</i> (Ucria) C.Presl). Three subquestion were answered through systematic review methodology. Sub-question 2 about the evidence for the extent to which the 1’-hydroxylation pathway is activated or sulphoconjugation of 1’-hydroxyestragole occurs at different levels of dietary exposure to estragole. Sub-question 3 regarding the effect of the matrix (i.e. preparations from sweet and bitter fennel fruits) on the sulphoconjugation of 1’-hydroxyestragole, on DNA adduct formation and on the carcinogenicity of estragole. Sub-question 5 on the content of estragole in preparations from sweet or bitter fennel fruits; on s the content of estragole, methyleugenol and safrole in herbs and spices that contain these p-allylalkoxybenzenes (e.g. aromatic herbs such as basil, spices such as nutmeg, etc.) and preparations from these herbs and spices in which the herb or the spice is one of the main ingredients (e.g. pesto); on the content of estragole, methyleugenol and safrole in compound foods, on the content of estragole, methyleugenol and safrole in food supplements. The search strategy was run on two databases, PubMed and Embase, and identified records were imported in Distiller SR software where the selection of relevant studies was carried out. Screening was carried out in parallel by two reviewers and conflicts were solved through consensus. At the end 27, 9 and 132 papers were included for subquestion 2, bub-question 3 and subquestion 5, respectively.</p>","PeriodicalId":100395,"journal":{"name":"EFSA Supporting Publications","volume":"22 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.2903/sp.efsa.2025.EN-9589","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144614926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Findings of not authorised substances in food and feed certified as organic","authors":"European Food Safety Authority (EFSA),&nbsp;Maria Anastassiadou,&nbsp;Mst Tazmin Akhter,&nbsp;Daniela Brocca,&nbsp;Luna Greco,&nbsp;Martin Josheski,&nbsp;Mariano Lopez Romano,&nbsp;Jose Oriol Magrans,&nbsp;Anamarija Romac,&nbsp;Miguel Santos,&nbsp;Tuuli Tauriainen","doi":"10.2903/sp.efsa.2025.EN-9524","DOIUrl":"https://doi.org/10.2903/sp.efsa.2025.EN-9524","url":null,"abstract":"<p>The European Commission requested EFSA to prepare a technical report on 21 active substances not authorised for use but detected more frequently in organic food/feed products according to notifications in the EU Organic Farming Information System (OFIS) between 2021 and 2022: fosetyl-Al, glyphosate, cypermethrin, imidacloprid, boscalid, tebuconazole, folpet, pirimiphos-methyl, azoxystrobin, fluopyram, lambda-cyhalothrin, acetamiprid, chlormequat, pendimethalin, spirotetramat, cyprodinil, chloridazon, pyriproxyfen, fludioxonil, difenoconazole and deltamethrin. The report focuses on organic food/feed of plant origin and apiculture products. It assesses the possible reasons behind the findings based on a broad spectrum of data sources: EFSA scientific Outputs, Member State reports, the EU OFIS, pesticides, biocides, veterinary medicines and chemical occurrence databases, food/feed and environmental monitoring data from the Information Platform for Chemical Monitoring, data from the EU Sustainable Plant Protection Transition project, industrial emissions portal and the literature. The report integrates inputs from a Technical Support Group composed of experts from the Joint Research Centre, European Chemicals Agency, European Environmental Agency and EFSA. None of the active substances occurs naturally. For each substance, several possible sources of residues were identified. When residues are quantified in organic products, investigation to confirm/exclude active unauthorised use of the substance is recommended. When phosphonic acid (metabolite of fosetyl and phosphonates), boscalid, fluopyram and difenoconazole are quantified in organic products, analysis of the soil where the plants were grown is recommended. When glyphosate, boscalid, azoxystrobin, fluopyram and spirotetramat are quantified in organic products, analysis of the water used to irrigate the plants is recommended. To confirm/exclude possible drift from conventional crops in the vicinity of organic crops, investigation of pesticide use around the area of the organic production site is recommended. Long/medium-range aerial transport of residues, transfer via water pathways or cross-contamination are other potential sources of residues in plants. Transfer of residues from industrial activity is unlikely.</p>","PeriodicalId":100395,"journal":{"name":"EFSA Supporting Publications","volume":"22 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.2903/sp.efsa.2025.EN-9524","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144606488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pest survey card on Pseudocercospora pini-densiflorae","authors":"European Food Safety Authority (EFSA),&nbsp;Alessandra Gionni,&nbsp;Francesco Pecori,&nbsp;Alberto Santini,&nbsp;Cecile Robin,&nbsp;Daria Rzepecka,&nbsp;Melanie Camilleri,&nbsp;Francesca Salinari","doi":"10.2903/sp.efsa.2025.EN-9150","DOIUrl":"https://doi.org/10.2903/sp.efsa.2025.EN-9150","url":null,"abstract":"<p>This document provides the conclusions of the pest survey card that was prepared in the context of the EFSA mandate on plant pest surveillance (M-2020-0114) at the request of the European Commission. The full pest survey card for <i>Pseudocercospora pini-densiflorae</i> is published and available online in the EFSA Pest Survey Card gallery at the following link and will be updated whenever new information becomes available: https://efsa.europa.eu/plants/planthealth/monitoring/surveillance/pseudocercospora-pini-densiflorae</p>","PeriodicalId":100395,"journal":{"name":"EFSA Supporting Publications","volume":"22 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.2903/sp.efsa.2025.EN-9150","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144598308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Plant Health Newsletter on HORIZON SCANNING June 2025","authors":"European Food Safety Authority (EFSA)","doi":"10.2903/sp.efsa.2025.EN-9587","DOIUrl":"https://doi.org/10.2903/sp.efsa.2025.EN-9587","url":null,"abstract":"","PeriodicalId":100395,"journal":{"name":"EFSA Supporting Publications","volume":"22 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.2903/sp.efsa.2025.EN-9587","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144573184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"preDQ – Update & Upgrade Update and maintenance of the preDQ – software tool for peptide binding prediction to HLA-DQ2 and HLA-DQ8 Re-evaluation of the logo models","authors":"Irini Doytchinova,&nbsp;Ivan Dimitrov,&nbsp;Mariyana Atanasova","doi":"10.2903/sp.efsa.2025.EN-9585","DOIUrl":"https://doi.org/10.2903/sp.efsa.2025.EN-9585","url":null,"abstract":"<p>preDQ is a software tool for prediction of peptides binding to HLA-DQ2 and HLA-DQ8 proteins, associated with susceptibility to celiac disease. preDQ was designed to evaluate the risk of novel proteins to cause celiac disease following EFSA's guidance on assessment of genetically modified plants. The predictive capability of preDQ relies on the utilization of five robust models, each producing five corresponding risk assessment outputs. These models have been developed using datasets containing both known binding and non-binding peptides to HLA-DQ2.5 and HLA-DQ8.1. The models were derived by ligand-based and structure-based computational methods and validated by internal cross-validation and external datasets. Only the highest-performing models have been implemented in preDQ. Overall, preDQ represents a comprehensive, user-friendly, and reliable tool for evaluating the binding affinity of peptides to HLA-DQ2.5 and HLA-DQ8.1 and the potential of the tested proteins to trigger celiac disease. Here, we propose a project aimed at updating, upgrading and maintaining of preDQ. As the authors of the software tool and the models that support it, we offer to update the datasets used to derive and validate the models, re-evaluate the existing models using the new data and derive new models, as well as maintain the tool, provide consistent feedback to users and stakeholders, publish the derived models in peer-reviewed journals and closely collaborate with EFSA experts.</p>","PeriodicalId":100395,"journal":{"name":"EFSA Supporting Publications","volume":"22 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.2903/sp.efsa.2025.EN-9585","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144573183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pest survey card on Sternochetus mangiferae","authors":"European Food Safety Authority (EFSA),&nbsp;Georgia D. Papadogiorgou,&nbsp;Eleftheria-Maria D. Bali,&nbsp;Niki K. Dionysopoulou,&nbsp;Georgios A. Kyritsis,&nbsp;Kostas D. Zarpas,&nbsp;Nikos T. Papadopoulos,&nbsp;Melanie Camilleri,&nbsp;Alicia Culot,&nbsp;Josep A. Jaques Miret,&nbsp;Giulia Mattion,&nbsp;Laura Carotti","doi":"10.2903/sp.efsa.2025.EN-9517","DOIUrl":"https://doi.org/10.2903/sp.efsa.2025.EN-9517","url":null,"abstract":"<p>This document provides the conclusions of the pest survey card that was prepared in the context of the EFSA mandate on plant pest surveillance (M-2020-0114) at the request of the European Commission. The full pest survey card for <i>Sternochetus mangiferae</i> is published and available online in the EFSA Pest Survey Card gallery at the following link and will be updated whenever new information becomes available: https://efsa.europa.eu/plants/planthealth/monitoring/surveillance/sternochetus-mangiferae</p>","PeriodicalId":100395,"journal":{"name":"EFSA Supporting Publications","volume":"22 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.2903/sp.efsa.2025.EN-9517","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144537202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pest survey card on non-EU Gymnosporangium spp.","authors":"European Food Safety Authority (EFSA),&nbsp;Jane Debode,&nbsp;Fauve Maertens,&nbsp;Annemie Hoedekie,&nbsp;Eduardo de la Pena,&nbsp;Helena Romero,&nbsp;Juan Antonio Diaz-Pendon,&nbsp;Cesar Petri,&nbsp;Irene Vloutoglou,&nbsp;Melanie Camilleri","doi":"10.2903/sp.efsa.2025.EN-9502","DOIUrl":"https://doi.org/10.2903/sp.efsa.2025.EN-9502","url":null,"abstract":"<p>This document provides the conclusions of the pest survey card that was prepared in the context of the EFSA mandate on plant pest surveillance (M-2020-0114) at the request of the European Commission. The full pest survey card for non-EU <i>Gymnosporangium</i> spp. is published and available online in the EFSA Pest Survey Card gallery at the following link and will be updated whenever new information becomes available: https://efsa.europa.eu/plants/planthealth/monitoring/surveillance/non-eu-gymnosporangium</p>","PeriodicalId":100395,"journal":{"name":"EFSA Supporting Publications","volume":"22 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.2903/sp.efsa.2025.EN-9502","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144537201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Emerging Risk Analysis Platform (ERAP)","authors":"Dr Jevgeni Vihharev","doi":"10.2903/sp.efsa.2025.EN-9557","DOIUrl":"https://doi.org/10.2903/sp.efsa.2025.EN-9557","url":null,"abstract":"<p>This external scientific report documents the activities carried out by the scientific contractor within the Emerging Risk Analysis Platform (ERAP) project. It provides a consolidated and self-contained overview of the platform's development, testing, deployment, and user support. The report consolidates insights gathered throughout the entire project duration, including feedback from users and lessons learned during all project phases. It also outlines identified areas for improvement and presents proposals for future enhancements – including AI-related features. As such, the report provides a comprehensive overview of the ERAP project's progress and serves as a foundation for the platform's future development in alignment with the EFSA needs.</p>","PeriodicalId":100395,"journal":{"name":"EFSA Supporting Publications","volume":"22 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.2903/sp.efsa.2025.EN-9557","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144524896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Workshop held in Madrid regarding the collection of experiences and expectations of interested parties","authors":"Evangelos Karanasios,&nbsp;Filitsa Karamaouna,&nbsp;José Luis Alonso-Prados,&nbsp;Per Kudsk,&nbsp;Katerina Kyriakopoulou,&nbsp;Emilia Markellou,&nbsp;Dimosthenis Chachalis,&nbsp;Dimitrios Tsirogiannis,&nbsp;Theodora Nikolopoulou,&nbsp;Maira Lykogianni,&nbsp;Philippos Mylonas,&nbsp;Leonidas Economou,&nbsp;Panagiotis Milonas,&nbsp;Dimitrios Papachristos,&nbsp;Eleni Nasiou,&nbsp;Belén Guijarro Díaz-Otero,&nbsp;Antonieta de Cal Y Cortina,&nbsp;Inmaculada Larena Nistal,&nbsp;Paloma Melgarejo Nardíz,&nbsp;Manuel Gonzalez-Nuñez,&nbsp;Ismael Sánchez-Ramos,&nbsp;Iñigo Loureiro Beldarrain,&nbsp;María-Concepción Escorial Bonet,&nbsp;Maria Villarino Perez,&nbsp;Niels Matzen,&nbsp;Michael Kristensen,&nbsp;Mette Sønderskov","doi":"10.2903/sp.efsa.2025.EN-9500","DOIUrl":"https://doi.org/10.2903/sp.efsa.2025.EN-9500","url":null,"abstract":"<p>This report provides an overview of the first workshop held under the GP/EFSA/PLANTS/2023/02, titled “Support to urgent authorizations on Plant Health and Pesticides” project, which took place in Madrid, Spain. The objective of the workshop was to provide information on the objectives of the project and to present the outcomes of the preparatory work conducted by the implementation team to the representatives of various Member states. The meeting included an introductory session with inaugural speeches from EFSA and the project leader, followed by the main event comprising four breakout and one plenary session. All breakout groups covered the same topics, and participants exchanged views and provided valuable insights. The outcomes derived from these discussions was subsequently presented and deliberated in the plenary session. Key topics addressed during the workshop included sharing experiences related to existing protocols and expectations for future protocols, the evaluating criteria for effectiveness and feasibility of alternative control methods, as well as considerations pertinent to developing evaluation methodologies. It was noted that the emergency authorization process differs among Member States. Representatives shared their experiences on Article 4(7) Derogation protocol and EPPO Standard PP1/271, highlighting challenges encountered in their use. There was a consensus among Member States regarding the necessity for protocols on emergency authorisation that are user-friendly, practical, and adaptable to local conditions. Furthermore, Member States expressed support for creating a decision-making flowchart to facilitate emergency authorization processes and ensure uniform evaluations across all Member States.</p>","PeriodicalId":100395,"journal":{"name":"EFSA Supporting Publications","volume":"22 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.2903/sp.efsa.2025.EN-9500","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144524897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcome of the analysis of emergency authorisations which have been granted in EU Member States","authors":"Evangelos Karanasios,&nbsp;Filitsa Karamaouna,&nbsp;José Luis Alonso-Prados,&nbsp;Per Kudsk,&nbsp;Katerina Kyriakopoulou,&nbsp;Emilia Markellou,&nbsp;Dimosthenis Chachalis,&nbsp;Dimitrios Tsirogiannis,&nbsp;Theodora Nikolopoulou,&nbsp;Maira Lykogianni,&nbsp;Philippos Mylonas,&nbsp;Leonidas Economou,&nbsp;Panagiotis Milonas,&nbsp;Dimitrios Papachristos,&nbsp;Belén Guijarro Díaz-Otero,&nbsp;Antonieta de Cal y Cortina,&nbsp;Inmaculada Larena Nistal,&nbsp;Paloma Melgarejo Nardíz,&nbsp;Manuel Gonzalez-Nuñez,&nbsp;Ismael Sánchez-Ramos,&nbsp;Iñigo Loureiro Beldarrain,&nbsp;María-Concepción Escorial Bonet,&nbsp;Niels Matzen,&nbsp;Michael Kristensen,&nbsp;Mette Sønderskov","doi":"10.2903/sp.efsa.2025.EN-9499","DOIUrl":"https://doi.org/10.2903/sp.efsa.2025.EN-9499","url":null,"abstract":"<p>The analysis of all emergency authorisations issued by EU Member States over the past 10+ years is a preparatory action that supports the accomplishment of the objectives of the project and specifically the development of the inventory of alternatives control methods and the development of protocols for evaluation of emergency authorisation. All relevant information was sourced from the European Commission website. This extracted information was meticulously processed to create a format that facilitates filtering and presentation of results. The emergency authorisations were systematically analysed, sorted and grouped based on pest, crop and cropping system. The function of authorised formulations, the mode of action and the number of repeated emergency authorisations were considered in the analysis. Furthermore, a trend analysis was performed for identification of possible shifts in emergency needs over time. Between 2013 and 2024, a total of 4761 emergency authorisations were granted across EU Member States under Article 53, with the Southern zone accounting for the highest number of authorisations, followed by the Central zone and the Northern zone. The annual number of authorisations typically ranged between 620 and 720. Authorisations were most frequently issued for insecticides (37.6%), fungicides (20.5%), and herbicides (18.9%), with a smaller proportion involving multi-functional products (5.7%). A significant proportion (77%) of emergency authorisations were repeated over multiple years.</p>","PeriodicalId":100395,"journal":{"name":"EFSA Supporting Publications","volume":"22 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.2903/sp.efsa.2025.EN-9499","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144524898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}