EFSA Supporting Publications最新文献

{"title":"FoodEx2 maintenance 2025","authors":"European Food Safety Authority (EFSA),&nbsp;Krystalia Niforou,&nbsp;Sofia Ioannidou","doi":"10.2903/sp.efsa.2026.EN-10069","DOIUrl":"https://doi.org/10.2903/sp.efsa.2026.EN-10069","url":null,"abstract":"<p>FoodEx2, developed and maintained by EFSA, is a comprehensive system designed to classify and describe food and feed products. It provides a harmonised and standardised terminology framework that supports the entire food safety and risk assessment workflow, from data collection across multiple food and feed safety domains (e.g., monitoring of pesticides residues or biological hazards) to exposure assessment. To ensure the system remains relevant and aligned with evolving scientific and legislative requirements, regular updates are essential. To date, eight major updates have been completed, each documented in annual maintenance reports. This technical report presents the outcome of the ninth maintenance cycle carried out in 2025. The updates introduced include the addition of new terms, refinements to the hierarchical structure, revision to the reportability of selected terms, and amendments to existing terms – such as update to implicit facets, improvements to implicit attributes and scope notes and adjustments to parent-child relationships.</p>","PeriodicalId":100395,"journal":{"name":"EFSA Supporting Publications","volume":"23 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://efsa.onlinelibrary.wiley.com/doi/epdf/10.2903/sp.efsa.2026.EN-10069","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147715071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancement of the existing Pest Survey Card database and its associated web application","authors":"Saar Junius,&nbsp;Dagmar Bemelmans,&nbsp;Machteld Varewyck,&nbsp;Tobias Verbeke,&nbsp;Open Analytics NV","doi":"10.2903/sp.efsa.2026.EN-9979","DOIUrl":"10.2903/sp.efsa.2026.EN-9979","url":null,"abstract":"<p>In specific contract No 18 issued under the framework agreement OC/EFSA/MESE/2023/03, EFSA requested Open Analytics to restructure the Pest Survey Card database and to enhance the associated web application. The requested changes consist of a revised database structure that supports bulk validation processes, a new tab for a more efficient and user-friendly data management and a seamless integration of the newly structured database with the other existing Pest Surveillance applications (RiPest and OptiPest).</p>","PeriodicalId":100395,"journal":{"name":"EFSA Supporting Publications","volume":"23 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://efsa.onlinelibrary.wiley.com/doi/epdf/10.2903/sp.efsa.2026.EN-9979","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147684192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"2025 Annual Report of the Advisory Group on Data","authors":"European Food Safety Authority (EFSA),&nbsp;Fabrizio Abbinante,&nbsp;Dorte Lau Baggesen,&nbsp;Vittoria Flamini,&nbsp;David Foster,&nbsp;Klemens Fuchs,&nbsp;Nina Georgieva,&nbsp;Danica Grahek-Ogden,&nbsp;Ákos Jóźwiak,&nbsp;Dražen Knežević,&nbsp;Klervi Leuraud,&nbsp;Pedro Miguel Nabais,&nbsp;Andrea Maldonado,&nbsp;Michele de Martino,&nbsp;Eva Scharfenberg,&nbsp;Martina Stack,&nbsp;Katharina Stärk,&nbsp;Mikko Tuominen,&nbsp;Koen Wienk","doi":"10.2903/sp.efsa.2026.EN-10052","DOIUrl":"10.2903/sp.efsa.2026.EN-10052","url":null,"abstract":"<p>This report of the European Food Safety Authority (EFSA) Advisory Group on Data (AGoD) presents updates on the group's activities in 2025. The mission of the group is to identify and launch tangible projects solving the most pressing pain points of Member States and bringing benefits to the European food safety systems data and risk assessment community. In 2025, the group continued to action tasks under the five strategic areas of its 2024–2027 roadmap, these areas are data governance, data management, tools and ecosystems, people and capacity, and innovation. During 2025, the AGoD maintained its strong connections with other data and innovation initiatives, by receiving regular updates from EFSA's AI &amp; Innovation Board and inviting Member States and the European Commission to provide updates on relevant projects. These connections allow for information exchange and the identification of possible collaborations. Following the success of the 2024 conference and with the formal establishment of the People and Capacity subgroup in 2025, cross-collaboration of the various AGoD subgroups continued in the form of a joint online meeting held in June 2025.</p>","PeriodicalId":100395,"journal":{"name":"EFSA Supporting Publications","volume":"23 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://efsa.onlinelibrary.wiley.com/doi/epdf/10.2903/sp.efsa.2026.EN-10052","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147684211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcome of the consultation with Member States, the applicant and EFSA on the pesticide risk assessment for cypermethrin in light of confirmatory information","authors":"European Food Safety Authority (EFSA)","doi":"10.2903/sp.efsa.2026.EN-10010","DOIUrl":"https://doi.org/10.2903/sp.efsa.2026.EN-10010","url":null,"abstract":"<p>The European Food Safety Authority (EFSA) was asked by the European Commission to provide scientific assistance with respect to the risk assessment of cypermethrin in light of confirmatory information requested following approval in accordance Article 6(f) of Regulation (EC) No 1107/2009. In this context EFSA's scientific views on the specific points raised during the commenting phase conducted with Member States, the applicant and EFSA on the confirmatory information and their use in the risk assessment of cypermethrin are presented. The current report summarises the outcome of the consultation process organised by the rapporteur Member State Belgium and presents EFSA's scientific views and conclusions on the individual comments received.</p>","PeriodicalId":100395,"journal":{"name":"EFSA Supporting Publications","volume":"23 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://efsa.onlinelibrary.wiley.com/doi/epdf/10.2903/sp.efsa.2026.EN-10010","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147585281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcome of the consultation with Member States, the applicant and EFSA on the pesticide risk assessment for cypermethrin in light of confirmatory information","authors":"European Food Safety Authority (EFSA)","doi":"10.2903/sp.efsa.2026.EN-10010","DOIUrl":"https://doi.org/10.2903/sp.efsa.2026.EN-10010","url":null,"abstract":"<p>The European Food Safety Authority (EFSA) was asked by the European Commission to provide scientific assistance with respect to the risk assessment of cypermethrin in light of confirmatory information requested following approval in accordance Article 6(f) of Regulation (EC) No 1107/2009. In this context EFSA's scientific views on the specific points raised during the commenting phase conducted with Member States, the applicant and EFSA on the confirmatory information and their use in the risk assessment of cypermethrin are presented. The current report summarises the outcome of the consultation process organised by the rapporteur Member State Belgium and presents EFSA's scientific views and conclusions on the individual comments received.</p>","PeriodicalId":100395,"journal":{"name":"EFSA Supporting Publications","volume":"23 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://efsa.onlinelibrary.wiley.com/doi/epdf/10.2903/sp.efsa.2026.EN-10010","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147585282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of an adverse outcome pathway network for reproductive toxicity endpoints to support identification of endocrine disrupters","authors":"Terje Svingen,&nbsp;Monica K. Draskau,&nbsp;Marie L. Holmer,&nbsp;Johanna Zilliacus,&nbsp;Nora Bouftas,&nbsp;Anna K. Rosenmai,&nbsp;Eleftheria M. Panagiotou,&nbsp;Emilie Elmelund,&nbsp;Hanna K.L. Johansson,&nbsp;Eleni Barmpari,&nbsp;Henrieta Hlisnikova,&nbsp;Sofie Christiansen,&nbsp;Anna O. Bindel,&nbsp;Majorie van Duursen,&nbsp;Pauliina Damdimopoulou,&nbsp;Anna Beronius","doi":"10.2903/sp.efsa.2026.EN-9974","DOIUrl":"10.2903/sp.efsa.2026.EN-9974","url":null,"abstract":"<p>Development of adverse outcome pathways (AOPs) can support the implementation of the EFSA–ECHA Guidance (2018) for identifying endocrine disruptors under EU Regulations 528/2012 and 1107/2009. However, their regulatory utility depends on them being fully developed and OECD-endorsed, and in many cases their incorporation into more extensive AOP networks (AOPNs). To accelerate this process, EFSA has prioritized the creation of AOPNs spanning estrogenic, androgenic, steroidogenic, and thyroid (EATS) modalities, with an initial focus on mammalian reproductive toxicity driven by estrogenic, androgenic, and steroidogenic (EAS) disruption. In this context, this project developed a foundational AOPN capturing anti-androgenic mechanisms that converge on key regulatory outcomes, including reduced anogenital distance, nipple retention, hypospadias, and impaired fertility. This AOPN currently includes 10 fully developed AOP. Additional developments under the project includes upstream networks for androgen, estrogen, and steroidogenesis modalties. The work establishes a modular architecture in which upstream molecular signaling pathways feed into shared developmental key events, thereby enabling integration of diverse mechanistic data and supporting transparent tracking of causal evidence. By mapping conserved pathways and identifying mechanistic nodes with high regulatory relevance, the framework also highlights critical knowledge gaps that hinder robust AOP expansion. The project incorporated standardized AOP-Wiki methodologies to strengthen consistency in reporting and facilitate future network growth, while methodological advances such as refined weight-of-evidence procedures, systematic network-mapping approaches, and strategies for building data-rich key event relationships enhance reproducibility and evaluative confidence. Together, these developments can increase the practical value of AOPN for chemical evaluation and risk assessment, support alignment with emerging new approach methodologies (NAMs) for endocrine disruptor identification and provide a scalable foundation for future AOP and AOPN development.</p>","PeriodicalId":100395,"journal":{"name":"EFSA Supporting Publications","volume":"23 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://efsa.onlinelibrary.wiley.com/doi/epdf/10.2903/sp.efsa.2026.EN-9974","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147683911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"2025 Annual Report of the Advisory Group on Biomarkers of Effect","authors":"European Food Safety Authority (EFSA),&nbsp;Dimosthenis Sarigiannis,&nbsp;Manca Ahačič,&nbsp;Anne Mette Zenner Boisen,&nbsp;Francesco Capozzi,&nbsp;Mark Cassar,&nbsp;Mariana Fernández,&nbsp;Marcel Mengelers,&nbsp;Mattias Öberg,&nbsp;Elliott James Price,&nbsp;Gilles Rivière,&nbsp;Milada Syčová,&nbsp;Tewes Tralau,&nbsp;Georgieva Tzveta,&nbsp;Ilse Van Overmeire,&nbsp;Susana Viegas,&nbsp;Ivana Vinković Vrček,&nbsp;Karolina Žiogelytė,&nbsp;Zainab Al Harraq,&nbsp;Mina Ristovska,&nbsp;Lucian Farcal","doi":"10.2903/sp.efsa.2026.EN-10047","DOIUrl":"10.2903/sp.efsa.2026.EN-10047","url":null,"abstract":"<p>The 2025 Annual Report of the Advisory Group on Biomarkers of Effect (AGoB) details the group's establishment, objectives, and activities in supporting EFSA's development of guidance on biomarkers of effect (BoEs) in regulatory risk assessment. The report outlines AGoB's collaborative efforts, meeting summaries, scientific advice and plans for future work.</p>","PeriodicalId":100395,"journal":{"name":"EFSA Supporting Publications","volume":"23 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://efsa.onlinelibrary.wiley.com/doi/epdf/10.2903/sp.efsa.2026.EN-10047","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147684067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multi-Agency Foresight with One Health Approach","authors":"Totti Könnölä,&nbsp;Arianna Ferrari,&nbsp;Susanne Giesecke,&nbsp;Kerstin Cuhls,&nbsp;Miquel Banchs-Piqué","doi":"10.2903/sp.efsa.2026.EN-10045","DOIUrl":"10.2903/sp.efsa.2026.EN-10045","url":null,"abstract":"<p>European societies are facing increasingly complex and interconnected challenges at the intersection of human, animal and environmental health. These challenges are driven by climate change, environmental degradation, technological transformation and geopolitical uncertainty. Addressing these challenges requires coordinated, anticipatory responses that transcend sectoral and agency-specific approaches. This report explores how multi-agency Foresight, grounded in a One Health perspective, can strengthen the European Union's capacity for anticipatory governance. Led by EFSA, the work was carried out by the Foresight on Demand Consortium in collaboration with members of the EU-ANSA Futures Cluster. The project combined horizon scanning, scenario development, participatory workshops, surveys and interviews. The analysis identifies changes that will shape future challenges and examines how different governance, technological and societal developments will influence preparedness, resilience and equity. Based on these findings, the report outlines strategic areas for multi-agency Foresight and suggests an adaptive, modular approach to Foresight that can be adapted to the different needs of EU agencies. The results will also be helpful to individual agencies in supporting their own strategic planning and programme development.</p>","PeriodicalId":100395,"journal":{"name":"EFSA Supporting Publications","volume":"23 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://efsa.onlinelibrary.wiley.com/doi/epdf/10.2903/sp.efsa.2026.EN-10045","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147684064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of the B-risk Biocides web application","authors":"Anne-Katrin Hess,&nbsp;Dagmar Bemelmans,&nbsp;Machteld Varewyck,&nbsp;Tobias Verbeke,&nbsp;Open Analytics NV","doi":"10.2903/sp.efsa.2026.EN-9997","DOIUrl":"10.2903/sp.efsa.2026.EN-9997","url":null,"abstract":"<p>In specific contract No 12 issued under the framework agreement OC/EFSA/MESE/2023/03, EFSA requested Open Analytics to implement a web application to do a risk assessment for honeybees, solitary bees and bumble bees regarding the use of biocidal products. The software is developed in R and consists of a web-based tool composed by several modules providing data entry for active substances, uses, metabolites and the modelling of toxicity studies. The application is developed based on the already existing EFSA's web application B-risk for plant protection products (PPP) in a modular form such that new modules can be added when available, either by the developers of the application or by EFSA.</p>","PeriodicalId":100395,"journal":{"name":"EFSA Supporting Publications","volume":"23 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://efsa.onlinelibrary.wiley.com/doi/epdf/10.2903/sp.efsa.2026.EN-9997","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147684065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Protocol for the evaluation of emergency authorisations of fungicides and bactericides submitted under Article 53 of Regulation (EC) No 1107/2009","authors":"European Food Safety Authority (EFSA),&nbsp;Evangelos Karanasios,&nbsp;Filitsa Karamaouna,&nbsp;José Luis Alonso-Prados,&nbsp;Per Kudsk,&nbsp;Katerina Kyriakopoulou,&nbsp;Emilia Markellou,&nbsp;Dimosthenis Chachalis,&nbsp;Dimitrios Tsirogiannis,&nbsp;Theodora Nikolopoulou,&nbsp;Maira Lykogianni,&nbsp;Philippos Mylonas,&nbsp;Leonidas Economou,&nbsp;Panagiotis Milonas,&nbsp;Dimitrios Papachristos,&nbsp;Eleni Nasiou,&nbsp;Myrto Barda,&nbsp;Belén Guijarro Díaz-Otero,&nbsp;Antonieta de Cal y Cortina,&nbsp;Inmaculada Larena Nistal,&nbsp;Paloma Melgarejo Nardíz,&nbsp;Manuel Gonzalez-Nuñez,&nbsp;Ismael Sánchez-Ramos,&nbsp;Iñigo Loureiro Beldarrain,&nbsp;María-Concepción Escorial Bonet,&nbsp;Maria Villarino Pérez,&nbsp;Ana María Sánchez,&nbsp;Niels Matzen,&nbsp;Michael Kristensen,&nbsp;Mette Sønderskov,&nbsp;Franz Streissl","doi":"10.2903/sp.efsa.2026.EN-9992","DOIUrl":"https://doi.org/10.2903/sp.efsa.2026.EN-9992","url":null,"abstract":"<p>The protocol provides a structured approach for evaluating emergency authorisations of fungicides and bactericides under Article 53 of EU Regulation 1107/2009. It aims to standardise the evaluation of emergency authorisations, prioritise sustainable alternative solutions and ensure compliance with overarching EU strategies. Flowcharts were developed to harmonise the evaluation and to provide a structured evaluation process. A key aspect of the protocol is its flexibility to accommodate various emergency situations. The protocol includes provisions for more comprehensive evaluation in cases involving products with a less favourable profile, while considering the availability of alternative chemical and non-chemical control methods. It underscores the importance of transitioning from emergency authorisation to regular authorisation processes. Additionally, the methodology includes recommendations for repeated authorisations and the establishment of spatial and temporal conditions and restrictions of use. A central focus of the protocol is on fostering sustainable, long-term solutions in case of repeated authorisation requests. By aligning with regulatory frameworks and integrating stakeholder feedback, the protocol aims to improve transparency and efficiency in addressing emergency situations that cannot be managed through other reasonable means.</p>","PeriodicalId":100395,"journal":{"name":"EFSA Supporting Publications","volume":"23 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://efsa.onlinelibrary.wiley.com/doi/epdf/10.2903/sp.efsa.2026.EN-9992","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147566737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}