Comptes Rendus de l'Académie des Sciences - Series III - Sciences de la Vie最新文献_第2页

Removal of cell-bound lipoproteins: a crucial step for the efficient infection of liver cells with hepatitis C virus in vitro 细胞结合脂蛋白的去除:体外丙型肝炎病毒有效感染肝细胞的关键步骤

Comptes Rendus de l'Académie des Sciences - Series III - Sciences de la Vie Pub Date : 2001-12-01 DOI: 10.1016/S0764-4469(01)01397-X

Daniel Favre, Pascale Berthillon, Christian Trépo

{"title":"Removal of cell-bound lipoproteins: a crucial step for the efficient infection of liver cells with hepatitis C virus in vitro","authors":"Daniel Favre, Pascale Berthillon, Christian Trépo","doi":"10.1016/S0764-4469(01)01397-X","DOIUrl":"10.1016/S0764-4469(01)01397-X","url":null,"abstract":"<div><p>Hepatitis C virus (HCV) is of major social, medical and economic importance. The prevalence of HCV is approximatively 1 % in most developed countries, and much higher in developing countries. HCV infection is the second major cause, after hepatitis B virus infection, for the generation of chronic liver disease and hepatocellular carcinoma. To date, the only reliable model for the study of HCV infection is the chimpanzee. Indeed, there is no robust in vitro infection system, yet. There is thus an urgent need for such an in vitro infection system in order to evaluate therapeutic agents. Here, a process is provided for infecting hepatocyte cell lines with hepatitis C virus in vitro. It is strongly suggested that cell-bound lipoproteins are playing a crucial role during the infection process. In order to obtain a robust infection, the cell-bound lipoproteins have first to be removed from their cellular receptor prior to the addition of viral inocula originating from human sera, the latter being made originally of a virus-lipoprotein complex.</p></div>","PeriodicalId":100306,"journal":{"name":"Comptes Rendus de l'Académie des Sciences - Series III - Sciences de la Vie","volume":"324 12","pages":"Pages 1141-1148"},"PeriodicalIF":0.0,"publicationDate":"2001-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0764-4469(01)01397-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78230531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 19

Differences in the social context of song production in captive male and female European starlings 圈养欧洲椋鸟雌雄鸣叫的社会背景差异

Comptes Rendus de l'Académie des Sciences - Series III - Sciences de la Vie Pub Date : 2001-12-01 DOI: 10.1016/S0764-4469(01)01394-4

Laurence Henry , Martine Hausberger

引用次数: 23

Valeur prédictive des types biologiques pour la conservation de la flore méditerranéenne 生物类型对地中海植物群保护的预测价值

Comptes Rendus de l'Académie des Sciences - Series III - Sciences de la Vie Pub Date : 2001-12-01 DOI: 10.1016/S0764-4469(01)01406-8

Régine Verlaque , Frédéric Médail , Annie Aboucaya

{"title":"Valeur prédictive des types biologiques pour la conservation de la flore méditerranéenne","authors":"Régine Verlaque , Frédéric Médail , Annie Aboucaya","doi":"10.1016/S0764-4469(01)01406-8","DOIUrl":"10.1016/S0764-4469(01)01406-8","url":null,"abstract":"<div><p>The validity of Raunkiaer’s biological types (or life-forms) was tested on native Corsican flora, using criteria of altitudinal distribution and rarity. The biological basis of this classification has been widely confirmed. The analysis of floras from Corsica and Provence revealed the major role played by both altitude and human impact, and also demonstrated the importance of the predictive value of life-forms to plant conservation. In Southeastern France, there are no clear proportional relationships between rarity and extinction percentages. With increasing levels of human activity, rarity percentages are seen to increase for nearly all types. Conversely, extinction percentages exhibit a clear progression only for the most threatened life-forms: bulb and tuber geophytes, therophytes, parasites and especially hydrophytes. Thus, priority should be given to the protection of these 4 herbaceous types, which are found at low altitudes and lack visible vegetative organs during the unfavourable season.</p></div>","PeriodicalId":100306,"journal":{"name":"Comptes Rendus de l'Académie des Sciences - Series III - Sciences de la Vie","volume":"324 12","pages":"Pages 1157-1165"},"PeriodicalIF":0.0,"publicationDate":"2001-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0764-4469(01)01406-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77796546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 29

Environment, genome and cancer 环境，基因组和癌症

Comptes Rendus de l'Académie des Sciences - Series III - Sciences de la Vie Pub Date : 2001-12-01 DOI: 10.1016/S0764-4469(01)01399-3

Lu Wang, Sai-Juan Chen

引用次数: 6

Free availability of the human genome sequence data and confidentiality of the individual genetic information: A written talk at: Genomics 2000: science and mankind, Annecy, France 1-6 May, 2000 人类基因组序列数据的免费获取和个人遗传信息的保密性:2000年5月1日至6日在法国安纳西举行的“基因组学2000:科学与人类”会议上的书面报告

Comptes Rendus de l'Académie des Sciences - Series III - Sciences de la Vie Pub Date : 2001-12-01 DOI: 10.1016/S0764-4469(01)01401-9

Huanming Yang

引用次数: 0

Genomics and early cellular evolution. The origin of the DNA world 基因组学和早期细胞进化。DNA世界的起源

Comptes Rendus de l'Académie des Sciences - Series III - Sciences de la Vie Pub Date : 2001-12-01 DOI: 10.1016/S0764-4469(01)01403-2

Patrick Forterre

{"title":"Genomics and early cellular evolution. The origin of the DNA world","authors":"Patrick Forterre","doi":"10.1016/S0764-4469(01)01403-2","DOIUrl":"10.1016/S0764-4469(01)01403-2","url":null,"abstract":"<div><p>The sequencing of several genomes from each of the three domains of life (Archaea, Bacteria and Eukarya) has provided a huge amount of data that can be used to gain insight about early cellular evolution. Some features of the universal tree of life based on rRNA polygenies have been confirmed, such as the division of the cellular living world into three domains. The monophyly of each domain is supported by comparative genomics. However, the hyperthermophilic nature of the ‘last universal common ancestor’ (LUCA) is not confirmed. Comparative genomics has revealed that gene transfers have been (and still are) very frequent in genome evolution. Nevertheless, a core of informational genes appears more resistant to transfer, testifying for a close relationship between archaeal and eukaryal informational processes. This observation can be explained either by a common unique history between Archaea and Eukarya or by an atypical evolution of these systems in Bacteria. At the moment, comparative genomics still does not allow to choose between a simple LUCA, possibly with an RNA genome, or a complex LUCA, with a DNA genome and informational mechanisms similar to those of Archaea and Eukarya. Further comparative studies on informational mechanisms in the three domains should help to resolve this critical question. The role of viruses in the origin and evolution of DNA genomes also appears an area worth of active investigations. I suggest here that DNA and DNA replication mechanisms appeared first in the virus world before being transferred into cellular organisms.</p></div>","PeriodicalId":100306,"journal":{"name":"Comptes Rendus de l'Académie des Sciences - Series III - Sciences de la Vie","volume":"324 12","pages":"Pages 1067-1076"},"PeriodicalIF":0.0,"publicationDate":"2001-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0764-4469(01)01403-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75202790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 47

Index 指数

Comptes Rendus de l'Académie des Sciences - Series III - Sciences de la Vie Pub Date : 2001-12-01 DOI: 10.1016/S0764-4469(01)01415-9

引用次数: 0

Identifying main evolutionary mechanisms shaping genetic variation of Leuciscus cephalus L. 1758 (Cyprinidae) in Western Greece: discordance between methods 鉴定西希腊斑马鱼(Leuciscus cephalus L. 1758)遗传变异的主要进化机制:方法间的不一致

Comptes Rendus de l'Académie des Sciences - Series III - Sciences de la Vie Pub Date : 2001-11-01 DOI: 10.1016/S0764-4469(01)01361-0

Bruno Guinand , Jean-Dominique Durand , Jean Laroche

{"title":"Identifying main evolutionary mechanisms shaping genetic variation of Leuciscus cephalus L. 1758 (Cyprinidae) in Western Greece: discordance between methods","authors":"Bruno Guinand , Jean-Dominique Durand , Jean Laroche","doi":"10.1016/S0764-4469(01)01361-0","DOIUrl":"10.1016/S0764-4469(01)01361-0","url":null,"abstract":"<div><p>Numerous methods can be used in intraspecific phylogeographic studies to infer the evolutionary mechanisms that shaped observed genetic variation in populations. However, these methods are scarcely used jointly, and the evolutionary outcomes they could propose are not fully compared. In this study, using a chub (<em>Leuciscus cephalus</em>; Cyprinidae) mitochondrial DNA data set (13 populations in Western Greece, 14 haplotypes), we compare three distinct ‘historical’ methods that could possibly infer relative importance of basic evolutionary mechanisms (isolation vs migration) shaping genetic variation: the nested clade analysis, the <em>Ψ</em>-test and the ‘mismatch distributions’. Taking together, interpretations of these analyses allow to draw a picture of the evolutionary history of chub in Western Greece based on isolation and genetic drift for higher clades. However, results issued each method can differ for low differentiated clades. We discuss such differences and suggest that methods should be used jointly in phylogeographic studies for a better evaluation of the evolutionary mechanisms that shaped genetic variation.</p></div>","PeriodicalId":100306,"journal":{"name":"Comptes Rendus de l'Académie des Sciences - Series III - Sciences de la Vie","volume":"324 11","pages":"Pages 1045-1060"},"PeriodicalIF":0.0,"publicationDate":"2001-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0764-4469(01)01361-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89667521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Experience modulates emission of food calls in broody hens 经验调节产蛋母鸡发出的食物叫声

Comptes Rendus de l'Académie des Sciences - Series III - Sciences de la Vie Pub Date : 2001-11-01 DOI: 10.1016/S0764-4469(01)01362-2

Aline-Marie Wauters, Marie-Annick Richard-Yris

引用次数: 3

Passé larvaire des civelles, Anguilla anguilla (Linné, 1758) en migration en zones côtière et estuarienne (Adour, golfe de Gascogne) à partir de l’examen des otolithes 安圭拉(linne, 1758)在沿海和河口地区(Adour，比斯开湾)通过对耳石的检查迁徙

Comptes Rendus de l'Académie des Sciences - Series III - Sciences de la Vie Pub Date : 2001-11-01 DOI: 10.1016/S0764-4469(01)01378-6

Marie-Noëlle de Casamajor , Raymonde Lecomte-Finiger , Patrick Prouzet

{"title":"Passé larvaire des civelles, Anguilla anguilla (Linné, 1758) en migration en zones côtière et estuarienne (Adour, golfe de Gascogne) à partir de l’examen des otolithes","authors":"Marie-Noëlle de Casamajor , Raymonde Lecomte-Finiger , Patrick Prouzet","doi":"10.1016/S0764-4469(01)01378-6","DOIUrl":"10.1016/S0764-4469(01)01378-6","url":null,"abstract":"<div><p>The embryonic past of glass eels was studied from the interpretation of microstructures registered on otoliths. The aim of this work is to put in evidence possible seasonal modifications of the growth of otoliths so that differences between otoliths of glass eels caught off marine and estuarine environment. So during the season 1999–2000, from November till March, otolith sampling was realised in the southwestern part of France, in an estuarine and coastal zone. We observed a spatial and temporal evolution of proportions of the three various types of otoliths taken into account. Glass eels sampled at sea sometimes have a mark on their otoliths indicating the transition in the estuary, especially at the end of the fishing season. Measures of growth marks of otoliths showed that there were no seasonal differences during phases of the transoceanic migration and the crossing of the continental shelf. The radius of otoliths of glass eels sampled at sea was significantly smaller than those sampled in estuary. These results translated homogeneous environmental modifications met by the various larvae groups during the oceanic crossing and during the principal migration season as well as a turn over of these groups during the transition between marine and continental environment.</p></div>","PeriodicalId":100306,"journal":{"name":"Comptes Rendus de l'Académie des Sciences - Series III - Sciences de la Vie","volume":"324 11","pages":"Pages 1011-1019"},"PeriodicalIF":0.0,"publicationDate":"2001-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0764-4469(01)01378-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77608562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 13