ChemistryEurope最新文献_第2页

Ligand-Dependent Chemoselectivity in Gold-Catalyzed Reactions between Anthranils and Diynamides. Formation of Spiro Azacyclic Compounds versus 1-Imino-1H-Indene-3-Carboximidamides 金催化的邻蒽醌与双酰胺反应中配体依赖的化学选择性。螺旋氮杂环化合物与1-亚胺- 1h -茚-3-碳胺酰胺的形成

ChemistryEurope Pub Date : 2025-05-24 DOI: 10.1002/ceur.202500068

Satish Bhausaheb Dawange, Rai-Shung Liu

引用次数: 0

Exploring the Reactivity of Germole Dianions with Aluminum Trichloride: Uncovering Versatile Pathways 探索德国钠离子与三氯化铝的反应性：揭示多种途径

ChemistryEurope Pub Date : 2025-05-23 DOI: 10.1002/ceur.202500081

Lena Albers, Marc Schmidtmann, Thomas Müller

{"title":"Exploring the Reactivity of Germole Dianions with Aluminum Trichloride: Uncovering Versatile Pathways","authors":"Lena Albers, Marc Schmidtmann, Thomas Müller","doi":"10.1002/ceur.202500081","DOIUrl":"https://doi.org/10.1002/ceur.202500081","url":null,"abstract":"The reactivity analysis of dipotassiumgermoldiides K2[1] with aluminum trichloride in the presence of donors uncovers an unexpectedly broad range of products. The specific product formed varies, based on the donor's characteristics, its size, and the stoichiometric ratio between the donor and the aluminium trichloride. This leads to the formation of various products, including alumole complexes of germanium 3(Do) (with Do = OEt2, iPr2Me2Im), cationic germole complexes of aluminylenes [14]+, and 2H-germole derivatives such as 15a. The alumole complexes of germanium 3 are structurally best described as nido-type clusters or aluminagerma[5]pyramidanes. They show significant Lewis acidity and can be isolated only in the form of their donor complexes 3(Do). The 2H-germole derivative 15a promises a high synthetic potential due to its unprecedented germenide (R2C = Ge(:)-R) group group, which is part of a butadiene system and substituted with a reactive C–Al functionality.","PeriodicalId":100234,"journal":{"name":"ChemistryEurope","volume":"3 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ceur.202500081","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144635619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dead Ends and Detours Towards a Rigid Hexasalicylic Aldehyde Precursor for Triptycene-Based Porous Materials 三苯基多孔材料刚性六水杨醛前驱体的死胡同和弯路

ChemistryEurope Pub Date : 2025-05-15 DOI: 10.1002/ceur.202580302

Dennis Reinhard, Sven M. Elbert, Wen-Shan Zhang, Frank Rominger, Rasmus R. Schröder, Michael Mastalerz

引用次数: 0

Mechanochemical Synthesis of Pillar[5]arene-based [c2]Daisy Chain Rotaxanes 柱状[5]芳烃基[c2]菊花链轮烷的机械化学合成

ChemistryEurope Pub Date : 2025-05-15 DOI: 10.1002/ceur.202580301

Dr. Boram Park, Dr. Iwona Nierengarten, Dr. Jean-François Nierengarten

引用次数: 0

Lumos: A β-Diketone-Derived Artificial Nucleobase Forming Inter-Strand Complexes in DNA that Promote Lanthanoid Ion Luminescence Lumos：一种β-二酮衍生的人工核碱基，在DNA中形成链间复合物，促进类镧离子发光

ChemistryEurope Pub Date : 2025-05-15 DOI: 10.1002/ceur.202580303

Carla Bardehle, Marian Hebenbrock, Alexander Hepp, Jens Müller

引用次数: 0

Probing Effects of Electron Addition to Polycyclic Conjugated Hydrocarbons Containing Four-Membered Rings 含四元环的多环共轭烃的电子加成探测效应

ChemistryEurope Pub Date : 2025-05-08 DOI: 10.1002/ceur.202500047

Yikun Zhu, Ke Zheng, Zheng Wei, Yan Xia, Marina A. Petrukhina

{"title":"Probing Effects of Electron Addition to Polycyclic Conjugated Hydrocarbons Containing Four-Membered Rings","authors":"Yikun Zhu, Ke Zheng, Zheng Wei, Yan Xia, Marina A. Petrukhina","doi":"10.1002/ceur.202500047","DOIUrl":"https://doi.org/10.1002/ceur.202500047","url":null,"abstract":"The rectangular cyclobutadiene (CBD, C4H4) is a unique moiety for building nonbenzenoid polycyclic conjugated hydrocarbons with interesting electron-accepting properties. Herein, the investigation on chemical reduction of several CBD-containing polycyclic hydrocarbons with increasing conjugation length is reported: biphenylene (C12H8), dimethyl[2]naphthalene (C22H16), and tetramethyl-dibenzo-[3]phenylene (C30H22). The two-step sequential reduction is first demonstrated by in situ spectroscopic investigation and then confirmed by the isolation of single crystals of the reduced products. The X-ray crystallographic analysis reveals the formation of several mono- and doubly reduced products in solvent-separated and complexed forms. The crystal structures for both neutral parents and corresponding reduced products unravel the changes in bond alternation in each ring of the fused systems. Density functional theory (DFT) and nucleus-independent chemical shift (NICS) scan calculations reveal that the two-electron addition reduces the aromatic character in the benzenoid rings but has minor influence on the antiaromatic CBD rings.","PeriodicalId":100234,"journal":{"name":"ChemistryEurope","volume":"3 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ceur.202500047","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144635363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparative Study of Platinum(II) and Platinum(IV) Complexes with 2-(Pyridin-2-ylmethylamino)acetic Acid and 4-(Pyridin-2-ylmethylamino)benzoic Acid: Experimental and Theoretical Analysis 铂（II）和铂（IV）与2-（吡啶-2-基甲胺）乙酸和4-（吡啶-2-基甲胺）苯甲酸配合物的比较研究：实验和理论分析

ChemistryEurope Pub Date : 2025-05-07 DOI: 10.1002/ceur.202500049

Stefan Richter, Dušan Dimić, Peter Lönnecke, Goran N. Kaluđerović, Evamarie Hey-Hawkins

{"title":"Comparative Study of Platinum(II) and Platinum(IV) Complexes with 2-(Pyridin-2-ylmethylamino)acetic Acid and 4-(Pyridin-2-ylmethylamino)benzoic Acid: Experimental and Theoretical Analysis","authors":"Stefan Richter, Dušan Dimić, Peter Lönnecke, Goran N. Kaluđerović, Evamarie Hey-Hawkins","doi":"10.1002/ceur.202500049","DOIUrl":"https://doi.org/10.1002/ceur.202500049","url":null,"abstract":"The coordination behavior of 2-(2-pyridin-2-ylmethylamino)acetic acid (HL1) and 4-(2-pyridin-2-ylmethylamino)benzoic acid (HL2) toward PtII and PtIV is investigated. While the corresponding carboxylato complexes are obtained with HL1 (N,N,O coordination of L1−, elimination of HCl; 1a and 1b), only N,N coordination of HL2 which still features the carboxylic acid group is observed (2a and 2b). Thus, complexes 2a and 2b would be suitable for subsequent conjugation to biomolecules using the free COOH group. On heating in air, the ligand in 2a is oxidized (formal elimination of dihydrogen) to give the imine complex 3a, which could also be obtained directly from the corresponding ligand HL3 ((Z)-4-(pyridin-2-ylmethyleneamino)benzoic acid). The obtained complexes are characterized by 1H, 13C{1H} NMR and IR spectroscopy, elemental analysis, and, in the case of complexes 1a, 1b, and 3a, also by single-crystal X-ray crystallography. In addition, quantum chemical calculations are carried out to gain deeper insights into the molecular structures and properties of both the complexes and their precursor ligands. A comparative study showed that the theoretical calculations are in good agreement with the experimental findings. This combined experimental and theoretical approach facilitated a comprehensive understanding of the coordination behavior and structural features of the investigated complexes.","PeriodicalId":100234,"journal":{"name":"ChemistryEurope","volume":"3 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ceur.202500049","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144635192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Alcohol and Carbonyl Redox Reactions in Electrochemical Organic Synthesis 电化学有机合成中的醇和羰基氧化还原反应

ChemistryEurope Pub Date : 2025-05-06 DOI: 10.1002/ceur.202500013

Fiammetta Vitulano, Andrea Solida, Letizia Sorti, Carlo F. Morelli, Alessandro Minguzzi, Alberto Vertova

{"title":"Alcohol and Carbonyl Redox Reactions in Electrochemical Organic Synthesis","authors":"Fiammetta Vitulano, Andrea Solida, Letizia Sorti, Carlo F. Morelli, Alessandro Minguzzi, Alberto Vertova","doi":"10.1002/ceur.202500013","DOIUrl":"https://doi.org/10.1002/ceur.202500013","url":null,"abstract":"The primary aim of this review is to provide an overview of relevant and efficient methods in organic electrosynthesis, presented in a reader-friendly format. The focus is on the electrochemical oxidation of primary alcohols to aldehydes and carboxylic acids, the oxidation of aldehydes to carboxylic acids, and the oxidation of secondary alcohols to ketones. Additionally, the corresponding electrochemical reductions, such as the reduction of carboxylic acids to aldehydes and primary alcohols, the reduction of aldehydes to primary alcohols, and the reduction of ketones to secondary alcohols, are also covered. For each type of reaction, an easy-to-follow table provides readers with essential information (e.g., substrates, working electrode, electrolyte, cell type, synthesis notes, and references), enabling a quick yet comprehensive overview of the electrosynthetic possibilities for a given functional group. The review also explores recent advancements in organic electrosynthesis, encompassing both direct and mediated techniques. As electrochemical alternatives to classical organic synthesis continue to garner increasing attention, it is hoped that this review will serve as a valuable resource for those interested in evaluating these synthetic approaches.","PeriodicalId":100234,"journal":{"name":"ChemistryEurope","volume":"3 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ceur.202500013","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144635011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Energy Transfer Catalysis Enabled 2,2,2-Trifluoroethoxy-Amination of Olefins 能量转移催化使2,2,2-三氟乙氧基胺化烯烃

ChemistryEurope Pub Date : 2025-05-06 DOI: 10.1002/ceur.202500041

Floriane Doche, Thibault Gallavardin, Thomas Poisson, Tatiana Besset

{"title":"Energy Transfer Catalysis Enabled 2,2,2-Trifluoroethoxy-Amination of Olefins","authors":"Floriane Doche, Thibault Gallavardin, Thomas Poisson, Tatiana Besset","doi":"10.1002/ceur.202500041","DOIUrl":"https://doi.org/10.1002/ceur.202500041","url":null,"abstract":"A thioxanthone-catalyzed 2,2,2-trifluoroethoxyamination of olefins is developed via the formation of the corresponding alkoxy and iminyl radicals using unprecedented, easily prepared, and bench-stable oxime ethers as bifunctional reagents. To bypass possible side reactions (1,2-Hydrogen Atom Transfer (HAT), H-abstraction, and β-scission), the high reactivity of the alkoxy radical is fine-tuned to promote the selective and challenging formation of a COCH2CF3 bond. This reaction, involving a triplet energy transfer process, allows the concomitant formation of a CN and COAlk bond, so far uncharted, using bifunctional oxime ether reagents. Hence, the difunctionalization of a myriad of electron-rich alkenes selectively afforded the anti-Markovnikov products with a large functional group tolerance (44 examples, up to 77% yield), offering a straightforward and complementary regioselectivity compared to the existing approaches for the difunctionalization of alkenes with 2,2,2-trifluoroethanol. Post-functionalization reactions and mechanistic investigations provided key insights into the reaction mechanism of this transformation.","PeriodicalId":100234,"journal":{"name":"ChemistryEurope","volume":"3 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ceur.202500041","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144635009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Autoinductive Effects in Zinc-Catalyzed Alkylations of Benzaldehyde Mediated by Simple Chiral β-Amino Alcohol Ligands 简单手性β-氨基醇配体介导锌催化苯甲醛烷基化反应的自诱导效应

ChemistryEurope Pub Date : 2025-04-30 DOI: 10.1002/ceur.202500067

Joseph El Khoury, Thibault Thierry, Yannick Geiger, Stéphane Bellemin-Laponnaz

引用次数: 0