Lara Lopes , Joana Todi Monte , Sara Rodrigues , Celeste Baccarin Marangoni , Margarita Domingues Sousa , Ema Calçada , Larry Ibarra , Jorge Machado
{"title":"Individualized acupuncture for unilateral musculoskeletal pain: The advanced mathematical model","authors":"Lara Lopes , Joana Todi Monte , Sara Rodrigues , Celeste Baccarin Marangoni , Margarita Domingues Sousa , Ema Calçada , Larry Ibarra , Jorge Machado","doi":"10.1016/j.bbii.2023.100010","DOIUrl":"https://doi.org/10.1016/j.bbii.2023.100010","url":null,"abstract":"<div><p>Chronic musculoskeletal pain persists for longer than three months and is perceived to emerge from structures like bones, joints, and muscles. This condition interferes considerably in patients’ lives, leading to physical malfunction, psychological suffering, fatigue, social isolation, and job loss, resulting in a decrease in quality of life. Effective treatment remains a major challenge, highlighting the need for research to understand the complex underlying mechanisms. Recent studies have identified central neuroimmune activation and neuroinflammation as key contributors to the development of chronic pain, leading to central sensitization and reduced efficacy of opioid treatments. The number of clinical studies on the use of acupuncture for various types of pain has increased significantly in the last two decades showing a beneficial effect on pain relief and improving functional activities and psychological wellness. In our study, we decided to use a channel system and mathematical reasoning to resolve some chronic musculoskeletal pain. This method is grounded on an investigation of the historically described balancing systems, conducted by Schroeder et al. (2013) thus showing the extreme relevance of integrating psychoneuroimmunology and biopsychosocial details as necessary approaches to completely understand disease and illness. The results showed high efficiency and confirmed that the combination of more than two channels, somatotopic knowledge for the search for the right points on a balancing channel and the use of at least two types of needles helps preserve the balance of the treatment. More work should be done including studies in degenerative osteoarticular conditions.</p></div>","PeriodicalId":100197,"journal":{"name":"Brain Behavior and Immunity Integrative","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49731385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Recent progress in innate neuro-immunology holds great promises for the management of inflammatory diseases","authors":"Catherine Lathuillère , Philippe Georgel","doi":"10.1016/j.bbii.2023.100005","DOIUrl":"https://doi.org/10.1016/j.bbii.2023.100005","url":null,"abstract":"<div><p>Nervous and immune systems are devoted to threat identification and are essential for host survival (Fig. 1A). In this commentary, we shed light on papers that experimentally dissected the cross-talk between the nervous and the innate immune systems, using animal models and clinical trials. Next, we emphasize data showing how meditation can enable a control of the inflammatory status and provide some recent examples of high throughput genome-wide research that set the grounds for the elucidation of the immune/mind connections at the molecular level.</p></div>","PeriodicalId":100197,"journal":{"name":"Brain Behavior and Immunity Integrative","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49708214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mental health benefits of traditional Chinese medicine – An umbrella review of meta-analyses","authors":"Jorge Magalhães Rodrigues , Catarina Santos , Victor Ribeiro , António Silva , Lara Lopes , Jorge Pereira Machado","doi":"10.1016/j.bbii.2023.100013","DOIUrl":"https://doi.org/10.1016/j.bbii.2023.100013","url":null,"abstract":"<div><p>Mental health problems can be physically, emotionally and economically demanding, impacting patients, families, friends and society. Complementary techniques can help open up new possibilities for improving mental health worldwide. The aim of this study is to analyse the current evidence on the effectiveness of traditional Chinese medicine (TCM) for mental health and to inform potential applications within western healthcare settings. A systematic literature search was conducted in PubMed, Cochrane, Web of Science, Science Direct and Scielo databases to identify studies on TCM techniques for mental health. Meta-analyses on human subjects were included. Studies that examined mental health in other diseases were also included. Studies of low or moderate quality were excluded. Our literature search yielded 319 studies, 265 after removal of duplicates. After title and abstract screening, 40 studies were selected for retrieval. Full-text and quality assessment was performed on 38 studies, and 32 studies were included in the final analysis. The introduction of TCM into the health care system may have a positive impact on the treatment of certain mental illnesses and improve the quality of life of patients suffering from other diseases. TCM may also be useful for populations that do not have access to or receive conventional therapies. More studies are needed, and methodological quality needs to be improved. The protocol has been registered with the International Prospective Registry for Systematic Reviews (PROSPERO CRD42021276118).</p></div>","PeriodicalId":100197,"journal":{"name":"Brain Behavior and Immunity Integrative","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49731383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohamed A. Hassan , Suryeon Ryu , Kun Tao , Ru Wang , Minghui Quan , Zan Gao
{"title":"Young adults’ rating of perceived exertion and mood in exergaming dance and aerobic dance","authors":"Mohamed A. Hassan , Suryeon Ryu , Kun Tao , Ru Wang , Minghui Quan , Zan Gao","doi":"10.1016/j.bbii.2023.100007","DOIUrl":"https://doi.org/10.1016/j.bbii.2023.100007","url":null,"abstract":"<div><p>This study investigated mean differences in young adults’ rating of perceived exertion (RPE) and mood in different exercise modalities (exergaming aerobic dance vs. traditional aerobic dance). Forty young adults (20 females; M<sub>age</sub> = 20.38) completed two separate 12-minute dance sessions: 1) non-stop exergaming aerobic dance (Xbox 360 Kinect Just Dance - Just Sweat around the World); and 2) traditional aerobic dance led by an experienced instructor. Participants’ RPE was assessed via the Borg Rating of Perceived Exertion Scale (14-point Likert scale) every 4 min, and mood was measured by the Brunel Mood Scale (5-point Likert scale) following each session. MANOVA was used to detect mean differences in these outcomes between the two dance sessions. Results revealed significant differences between dance sessions for the overall model (p < 0.01). In detail, participants had significantly lower RPE toward exergaming dance compared to aerobic dance. In terms of mood, exergaming dance showed significantly lower confusion compared to aerobic dance (p < 0.05). Similarly, participants reported significantly lower fatigue in exergaming dance versus aerobic dance (p < 0.01). Findings suggest that exergaming dance may lead to less perceived RPE and fatigue among young adults compared to traditional aerobic dance.</p></div>","PeriodicalId":100197,"journal":{"name":"Brain Behavior and Immunity Integrative","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49708223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ivana Buric , Miguel Farias , Stoyan Kurtev , Valerie van Mulukom , Christopher Mee , Lloyd Gould , Sabeela Rehman , Barbara Parker , Inti A. Brazil
{"title":"Feasibility and preliminary outcomes of intensive mindfulness and yoga on prisoners with personality disorders: A randomised controlled preliminary study","authors":"Ivana Buric , Miguel Farias , Stoyan Kurtev , Valerie van Mulukom , Christopher Mee , Lloyd Gould , Sabeela Rehman , Barbara Parker , Inti A. Brazil","doi":"10.1016/j.bbii.2023.100009","DOIUrl":"https://doi.org/10.1016/j.bbii.2023.100009","url":null,"abstract":"<div><p>This study was the first to test the feasibility of mind-body interventions with a randomised control research design in a sample that contains all ten types of personality disorders, and the first to provide a preliminary evaluation of responses using a combination of psychological, genomic, neural, and behavioural measures. Thirty prisoners with personality disorders were recruited within a clinical unit of a high security prison and assigned to a mindfulness intervention (n=10), a yoga intervention (n=10), or a wait-list control group (n=10). Both mindfulness and yoga interventions were held simultaneously and lasted three hours per day on five consecutive days. At baseline and after the intervention, we measured inflammation-related gene expression through venous blood; attention with a cognitive task; event-related potentials (ERPs) with EEG; and stress, emotion regulation and mindfulness with questionnaires. Here we show that recruitment and dropout rates were satisfactory, and data collection was successful despite its length and complexity. The only exception were blood samples where 60% of participants refused to give blood, but this was expected because 47% of recruited participants had a diagnosis of paranoid personality disorder. Unexpected difficulties occurred when participants did not fully adhere to randomisation procedures, and a riot took place during the final day of the interventions. This study was underpowered to detect changes on primary or secondary outcome measures, but despite that 80% of examined inflammation-related genes showed medium and large effect sizes suggesting this as an important outcome measure in future studies. Minor adjustments to the study design are necessary before a larger scale study can be conducted to precisely determine the effects of mindfulness and yoga as an additional treatment for prisoners with personality disorders.</p></div>","PeriodicalId":100197,"journal":{"name":"Brain Behavior and Immunity Integrative","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49708190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Suryeon Ryu , Ning Liao , Daniel J. McDonough , Zan Gao
{"title":"Chinese breast cancer survivors’ functional fitness, biomarkers, and physical activity determinants and behaviors: A descriptive study","authors":"Suryeon Ryu , Ning Liao , Daniel J. McDonough , Zan Gao","doi":"10.1016/j.bbii.2023.100003","DOIUrl":"https://doi.org/10.1016/j.bbii.2023.100003","url":null,"abstract":"<div><h3>Purpose</h3><p>This study aimed to investigate significant predictors for physical activity (PA) and cancer biomarkers of Chinese breast cancer survivors (BCS), as well as whether differences existed in PA adherence and body mass index (BMI).</p></div><div><h3>Methods</h3><p>One hundred sixty-eight BCS (mean age = 44.81 years old) participated in the study. Validated surveys discerned PA engagement and psychosocial beliefs. Other outcomes included lipid profiles, fasting serum glucose, cancer biomarkers (i.e., carcinoembryonic antigen [CEA] and cancer antigen15–3 [CA15–3]), and functional fitness.</p></div><div><h3>Results</h3><p>Results demonstrated that self-efficacy, friend support, lower-right body flexibility, and upper-left body flexibility were significant predictors of participants’ PA levels. CEA significantly associated with participants’ triglycerides, one-hour glucose, and upper-right body strength. For CA15–3, glucose and upper-right body flexibility were significant predictors. No significant overall differences in health outcomes were observed by PA adherence. However, participants’ outcomes differed significantly by BMI.</p></div><div><h3>Conclusion</h3><p>We found several meaningful predictors of BCS’ PA and cancer biomarkers, which would benefit healthier cancer survivorship. Taken together, the study is imperative for healthcare professionals to realize the importance of promoting a physically active lifestyle and reducing the prevalence of obesity in breast cancer survivors.</p></div>","PeriodicalId":100197,"journal":{"name":"Brain Behavior and Immunity Integrative","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49709983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Keith W. Kelley , Weiwen Wang , Liye Zou , Carmine Pariante
{"title":"It’s time for psychoneuroimmunology to focus on Asian health practices and medicine: Introducing Brain, Behavior, and Immunity-Integrative","authors":"Keith W. Kelley , Weiwen Wang , Liye Zou , Carmine Pariante","doi":"10.1016/j.bbii.2022.100001","DOIUrl":"https://doi.org/10.1016/j.bbii.2022.100001","url":null,"abstract":"","PeriodicalId":100197,"journal":{"name":"Brain Behavior and Immunity Integrative","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49710157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effects of home-based exergaming on preschool children’s cognition, sedentary behavior, and physical activity: A randomized crossover trial","authors":"Nan Zeng , Jung Eun Lee , Zan Gao","doi":"10.1016/j.bbii.2023.100002","DOIUrl":"https://doi.org/10.1016/j.bbii.2023.100002","url":null,"abstract":"<div><h3>Purpose</h3><p>Exergaming’s potential to promote young children’s cognition and health remains largely unknown. This randomized crossover trial was to evaluate the preliminary effects of an educational exergaming program (LeapTV™) versus usual practice on preschool children’s executive function (EF), sedentary behavior (SB), and physical activity (PA).</p></div><div><h3>Methods</h3><p>A total of 34 preschool children (17 girls, M<sub>age</sub> <!-->=<!--> <!-->4.72 ± 0.73 years; BMI-z = 0.39 ± 1.08) were randomized to either exergaming (30 min/day, 5 days/week) or usual practice condition for 12 weeks, followed by a 1-week washout period (week 13) and a second 12-week crossover phase. <em>T</em>he Dimensional Change Card Sort (DCCS) test was used to assess EF; SB, light PA, and moderate-to-vigorous PA (MVPA) were measured by ActiGraph GT3X+ accelerometers<em>.</em> All participants underwent identical assessments at baseline, week 13, and 26.</p></div><div><h3>Results</h3><p>After a 12-week intervention, both conditions displayed significant improvements in EF. Compared with usual practice, yet, exergaming increased children’s EF by 1.9 DCCS unit (95 % confidence interval [95 % CI], −0.34 to 4.04; <em>d</em> <!-->=<!--> <!-->0.22). Despite no other statistical differences were noted, compared with usual practice, exergaming decreased SB by 22.1 min (95 % CI, −25.22 to 18.98; <em>d</em> <!-->=<!--> <!-->0.29) and light PA by 9.56 min (95 % CI, −7.09 to −12.02; <em>d</em> <!-->=<!--> <!-->0.22), and increased MVPA by 4.05 min (95 % CI, 2.35–5.74; <em>d</em> <!-->=<!--> <!-->0.20).</p></div><div><h3>Conclusion</h3><p>This study demonstrates the LeapTV™ would promote meaningful improvements in preschool children’s EF and PA behaviors. Despite the promising efficacy, larger trials are needed to confirm our findings.</p></div>","PeriodicalId":100197,"journal":{"name":"Brain Behavior and Immunity Integrative","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49761322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}