Tawni L. Tidwell , Tenzin Namdul , Kristine E. Lee , Kevin M. Riordan , Natalie Skopicki , Tenzin Palkyi , Jetsun Jungney , Kristin Blake , Jetsun Cheme , Nyima Youdon Namseling , Dickyi Yangzom , Tsering Tsomo , Dawa Ridak , Yangbum Gyal , Tenzing Dakpa , Tsundu S. Nyinda , Nashalla G. Nyinda , Tsering Youdon , Anasuya Weil , Yangdron Kalzang , Melissa Rosenkranz
{"title":"藏药配方对非卧床的 SARS-CoV-2 感染者症状持续时间的影响:回顾性队列研究","authors":"Tawni L. Tidwell , Tenzin Namdul , Kristine E. Lee , Kevin M. Riordan , Natalie Skopicki , Tenzin Palkyi , Jetsun Jungney , Kristin Blake , Jetsun Cheme , Nyima Youdon Namseling , Dickyi Yangzom , Tsering Tsomo , Dawa Ridak , Yangbum Gyal , Tenzing Dakpa , Tsundu S. Nyinda , Nashalla G. Nyinda , Tsering Youdon , Anasuya Weil , Yangdron Kalzang , Melissa Rosenkranz","doi":"10.1016/j.bbii.2024.100051","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><p>Despite abundant data regarding factors that influence COVID-19 symptom severity and need for hospitalization, few studies examine time to resolution of symptoms and potential complementary and alternative therapies that may expedite outpatient recovery. Uncertainty in expected symptom duration and potential missed opportunities to decrease this time persist. Likewise, studies tracking outpatient COVID-19 experiences among marginalized communities are lacking.</p></div><div><h3>Objective</h3><p>To describe the impact of complex Tibetan herbal formula regimens on symptom duration among ambulatory patients with native SARS-CoV-2 infection.</p></div><div><h3>Methods</h3><p>This multi-center, cohort study assessed deidentified data from patients with laboratory-confirmed SARS-CoV-2 infection. The study assessed cases from March 12, 2020 to May 5, 2021 for which vaccinations were not available, and thus reflect native infections.</p></div><div><h3>Intervention</h3><p>Diagnoses were made via telemedicine by a traditional Tibetan medical physician, and herbal formulas were prescribed based on specific symptom presentation of COVID-19 using the personalized medicine approach integral to traditional Tibetan medicine.</p></div><div><h3>Results</h3><p>Of 145 patient cases assessed for eligibility, 86 (59.3%) met inclusion criteria, and 67 (46.2%) had documented symptom resolution. Resolution of symptoms occurred within a median [interquartile range (IQR)] of 11.7 (10.1–13.5) days. The most common symptoms reported were cough and fever. Time to recovery did not significantly differ based on symptom presentation at baseline, except for a couple symptom groupings such as headache and joint pain where recovery time was shorter when those symptoms were present.</p></div><div><h3>Conclusions and relevance</h3><p>Ambulatory patients diagnosed with SARS-CoV-2 infection receiving Tibetan herbal formulas had recovery from symptoms at a median of 11.7 days, fewer than other published reports in patients following standard of care. The Tibetan approach of targeting treatment based on symptom groups, especially those within classical Tibetan medical nosology, appears to result in quick symptom resolution.</p></div>","PeriodicalId":100197,"journal":{"name":"Brain Behavior and Immunity Integrative","volume":"5 ","pages":"Article 100051"},"PeriodicalIF":0.0000,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949834124000072/pdfft?md5=8e8726428dba56841522c11023441465&pid=1-s2.0-S2949834124000072-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Effect of Tibetan herbal formulas on symptom duration among ambulatory patients with native SARS-CoV-2 infection: A retrospective cohort study\",\"authors\":\"Tawni L. Tidwell , Tenzin Namdul , Kristine E. Lee , Kevin M. 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Likewise, studies tracking outpatient COVID-19 experiences among marginalized communities are lacking.</p></div><div><h3>Objective</h3><p>To describe the impact of complex Tibetan herbal formula regimens on symptom duration among ambulatory patients with native SARS-CoV-2 infection.</p></div><div><h3>Methods</h3><p>This multi-center, cohort study assessed deidentified data from patients with laboratory-confirmed SARS-CoV-2 infection. The study assessed cases from March 12, 2020 to May 5, 2021 for which vaccinations were not available, and thus reflect native infections.</p></div><div><h3>Intervention</h3><p>Diagnoses were made via telemedicine by a traditional Tibetan medical physician, and herbal formulas were prescribed based on specific symptom presentation of COVID-19 using the personalized medicine approach integral to traditional Tibetan medicine.</p></div><div><h3>Results</h3><p>Of 145 patient cases assessed for eligibility, 86 (59.3%) met inclusion criteria, and 67 (46.2%) had documented symptom resolution. Resolution of symptoms occurred within a median [interquartile range (IQR)] of 11.7 (10.1–13.5) days. The most common symptoms reported were cough and fever. Time to recovery did not significantly differ based on symptom presentation at baseline, except for a couple symptom groupings such as headache and joint pain where recovery time was shorter when those symptoms were present.</p></div><div><h3>Conclusions and relevance</h3><p>Ambulatory patients diagnosed with SARS-CoV-2 infection receiving Tibetan herbal formulas had recovery from symptoms at a median of 11.7 days, fewer than other published reports in patients following standard of care. The Tibetan approach of targeting treatment based on symptom groups, especially those within classical Tibetan medical nosology, appears to result in quick symptom resolution.</p></div>\",\"PeriodicalId\":100197,\"journal\":{\"name\":\"Brain Behavior and Immunity Integrative\",\"volume\":\"5 \",\"pages\":\"Article 100051\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S2949834124000072/pdfft?md5=8e8726428dba56841522c11023441465&pid=1-s2.0-S2949834124000072-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Brain Behavior and Immunity Integrative\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2949834124000072\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Brain Behavior and Immunity Integrative","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2949834124000072","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Effect of Tibetan herbal formulas on symptom duration among ambulatory patients with native SARS-CoV-2 infection: A retrospective cohort study
Background
Despite abundant data regarding factors that influence COVID-19 symptom severity and need for hospitalization, few studies examine time to resolution of symptoms and potential complementary and alternative therapies that may expedite outpatient recovery. Uncertainty in expected symptom duration and potential missed opportunities to decrease this time persist. Likewise, studies tracking outpatient COVID-19 experiences among marginalized communities are lacking.
Objective
To describe the impact of complex Tibetan herbal formula regimens on symptom duration among ambulatory patients with native SARS-CoV-2 infection.
Methods
This multi-center, cohort study assessed deidentified data from patients with laboratory-confirmed SARS-CoV-2 infection. The study assessed cases from March 12, 2020 to May 5, 2021 for which vaccinations were not available, and thus reflect native infections.
Intervention
Diagnoses were made via telemedicine by a traditional Tibetan medical physician, and herbal formulas were prescribed based on specific symptom presentation of COVID-19 using the personalized medicine approach integral to traditional Tibetan medicine.
Results
Of 145 patient cases assessed for eligibility, 86 (59.3%) met inclusion criteria, and 67 (46.2%) had documented symptom resolution. Resolution of symptoms occurred within a median [interquartile range (IQR)] of 11.7 (10.1–13.5) days. The most common symptoms reported were cough and fever. Time to recovery did not significantly differ based on symptom presentation at baseline, except for a couple symptom groupings such as headache and joint pain where recovery time was shorter when those symptoms were present.
Conclusions and relevance
Ambulatory patients diagnosed with SARS-CoV-2 infection receiving Tibetan herbal formulas had recovery from symptoms at a median of 11.7 days, fewer than other published reports in patients following standard of care. The Tibetan approach of targeting treatment based on symptom groups, especially those within classical Tibetan medical nosology, appears to result in quick symptom resolution.