藏药配方对非卧床的 SARS-CoV-2 感染者症状持续时间的影响:回顾性队列研究

Tawni L. Tidwell , Tenzin Namdul , Kristine E. Lee , Kevin M. Riordan , Natalie Skopicki , Tenzin Palkyi , Jetsun Jungney , Kristin Blake , Jetsun Cheme , Nyima Youdon Namseling , Dickyi Yangzom , Tsering Tsomo , Dawa Ridak , Yangbum Gyal , Tenzing Dakpa , Tsundu S. Nyinda , Nashalla G. Nyinda , Tsering Youdon , Anasuya Weil , Yangdron Kalzang , Melissa Rosenkranz
{"title":"藏药配方对非卧床的 SARS-CoV-2 感染者症状持续时间的影响:回顾性队列研究","authors":"Tawni L. Tidwell ,&nbsp;Tenzin Namdul ,&nbsp;Kristine E. Lee ,&nbsp;Kevin M. Riordan ,&nbsp;Natalie Skopicki ,&nbsp;Tenzin Palkyi ,&nbsp;Jetsun Jungney ,&nbsp;Kristin Blake ,&nbsp;Jetsun Cheme ,&nbsp;Nyima Youdon Namseling ,&nbsp;Dickyi Yangzom ,&nbsp;Tsering Tsomo ,&nbsp;Dawa Ridak ,&nbsp;Yangbum Gyal ,&nbsp;Tenzing Dakpa ,&nbsp;Tsundu S. Nyinda ,&nbsp;Nashalla G. Nyinda ,&nbsp;Tsering Youdon ,&nbsp;Anasuya Weil ,&nbsp;Yangdron Kalzang ,&nbsp;Melissa Rosenkranz","doi":"10.1016/j.bbii.2024.100051","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><p>Despite abundant data regarding factors that influence COVID-19 symptom severity and need for hospitalization, few studies examine time to resolution of symptoms and potential complementary and alternative therapies that may expedite outpatient recovery. Uncertainty in expected symptom duration and potential missed opportunities to decrease this time persist. Likewise, studies tracking outpatient COVID-19 experiences among marginalized communities are lacking.</p></div><div><h3>Objective</h3><p>To describe the impact of complex Tibetan herbal formula regimens on symptom duration among ambulatory patients with native SARS-CoV-2 infection.</p></div><div><h3>Methods</h3><p>This multi-center, cohort study assessed deidentified data from patients with laboratory-confirmed SARS-CoV-2 infection. The study assessed cases from March 12, 2020 to May 5, 2021 for which vaccinations were not available, and thus reflect native infections.</p></div><div><h3>Intervention</h3><p>Diagnoses were made via telemedicine by a traditional Tibetan medical physician, and herbal formulas were prescribed based on specific symptom presentation of COVID-19 using the personalized medicine approach integral to traditional Tibetan medicine.</p></div><div><h3>Results</h3><p>Of 145 patient cases assessed for eligibility, 86 (59.3%) met inclusion criteria, and 67 (46.2%) had documented symptom resolution. Resolution of symptoms occurred within a median [interquartile range (IQR)] of 11.7 (10.1–13.5) days. The most common symptoms reported were cough and fever. Time to recovery did not significantly differ based on symptom presentation at baseline, except for a couple symptom groupings such as headache and joint pain where recovery time was shorter when those symptoms were present.</p></div><div><h3>Conclusions and relevance</h3><p>Ambulatory patients diagnosed with SARS-CoV-2 infection receiving Tibetan herbal formulas had recovery from symptoms at a median of 11.7 days, fewer than other published reports in patients following standard of care. The Tibetan approach of targeting treatment based on symptom groups, especially those within classical Tibetan medical nosology, appears to result in quick symptom resolution.</p></div>","PeriodicalId":100197,"journal":{"name":"Brain Behavior and Immunity Integrative","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949834124000072/pdfft?md5=8e8726428dba56841522c11023441465&pid=1-s2.0-S2949834124000072-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Effect of Tibetan herbal formulas on symptom duration among ambulatory patients with native SARS-CoV-2 infection: A retrospective cohort study\",\"authors\":\"Tawni L. Tidwell ,&nbsp;Tenzin Namdul ,&nbsp;Kristine E. Lee ,&nbsp;Kevin M. Riordan ,&nbsp;Natalie Skopicki ,&nbsp;Tenzin Palkyi ,&nbsp;Jetsun Jungney ,&nbsp;Kristin Blake ,&nbsp;Jetsun Cheme ,&nbsp;Nyima Youdon Namseling ,&nbsp;Dickyi Yangzom ,&nbsp;Tsering Tsomo ,&nbsp;Dawa Ridak ,&nbsp;Yangbum Gyal ,&nbsp;Tenzing Dakpa ,&nbsp;Tsundu S. Nyinda ,&nbsp;Nashalla G. Nyinda ,&nbsp;Tsering Youdon ,&nbsp;Anasuya Weil ,&nbsp;Yangdron Kalzang ,&nbsp;Melissa Rosenkranz\",\"doi\":\"10.1016/j.bbii.2024.100051\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><p>Despite abundant data regarding factors that influence COVID-19 symptom severity and need for hospitalization, few studies examine time to resolution of symptoms and potential complementary and alternative therapies that may expedite outpatient recovery. Uncertainty in expected symptom duration and potential missed opportunities to decrease this time persist. Likewise, studies tracking outpatient COVID-19 experiences among marginalized communities are lacking.</p></div><div><h3>Objective</h3><p>To describe the impact of complex Tibetan herbal formula regimens on symptom duration among ambulatory patients with native SARS-CoV-2 infection.</p></div><div><h3>Methods</h3><p>This multi-center, cohort study assessed deidentified data from patients with laboratory-confirmed SARS-CoV-2 infection. The study assessed cases from March 12, 2020 to May 5, 2021 for which vaccinations were not available, and thus reflect native infections.</p></div><div><h3>Intervention</h3><p>Diagnoses were made via telemedicine by a traditional Tibetan medical physician, and herbal formulas were prescribed based on specific symptom presentation of COVID-19 using the personalized medicine approach integral to traditional Tibetan medicine.</p></div><div><h3>Results</h3><p>Of 145 patient cases assessed for eligibility, 86 (59.3%) met inclusion criteria, and 67 (46.2%) had documented symptom resolution. Resolution of symptoms occurred within a median [interquartile range (IQR)] of 11.7 (10.1–13.5) days. The most common symptoms reported were cough and fever. Time to recovery did not significantly differ based on symptom presentation at baseline, except for a couple symptom groupings such as headache and joint pain where recovery time was shorter when those symptoms were present.</p></div><div><h3>Conclusions and relevance</h3><p>Ambulatory patients diagnosed with SARS-CoV-2 infection receiving Tibetan herbal formulas had recovery from symptoms at a median of 11.7 days, fewer than other published reports in patients following standard of care. The Tibetan approach of targeting treatment based on symptom groups, especially those within classical Tibetan medical nosology, appears to result in quick symptom resolution.</p></div>\",\"PeriodicalId\":100197,\"journal\":{\"name\":\"Brain Behavior and Immunity Integrative\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S2949834124000072/pdfft?md5=8e8726428dba56841522c11023441465&pid=1-s2.0-S2949834124000072-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Brain Behavior and Immunity Integrative\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2949834124000072\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Brain Behavior and Immunity Integrative","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2949834124000072","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

背景尽管关于影响 COVID-19 症状严重程度和住院需求的因素有大量数据,但很少有研究对症状缓解的时间以及可能加快门诊康复的潜在补充和替代疗法进行研究。预期症状持续时间的不确定性以及可能错失减少症状持续时间的机会依然存在。同样,也缺乏对边缘化社区门诊病人 COVID-19 经历的跟踪研究。方法这项多中心队列研究评估了实验室确诊的 SARS-CoV-2 感染者的去身份数据。干预措施由传统藏医通过远程医疗进行诊断,并根据 COVID-19 的具体症状表现,采用传统藏医学中不可或缺的个性化医疗方法开具草药处方。结果在 145 例接受资格评估的患者中,86 例(59.3%)符合纳入标准,67 例(46.2%)有症状缓解的记录。症状缓解的中位数[四分位数间距 (IQR)] 为 11.7(10.1-13.5)天。最常见的症状是咳嗽和发烧。除了头痛和关节痛等几类症状出现时恢复时间较短外,其他症状的恢复时间与基线时出现的症状没有明显差异。结论和相关性确诊为 SARS-CoV-2 感染的非卧床病人接受藏药配方治疗后,症状恢复的中位数为 11.7 天,少于其他已发表的报告中采用标准治疗方法的病人。藏医根据症状群(尤其是经典藏医病名学中的症状群)进行针对性治疗的方法似乎能快速缓解症状。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effect of Tibetan herbal formulas on symptom duration among ambulatory patients with native SARS-CoV-2 infection: A retrospective cohort study

Background

Despite abundant data regarding factors that influence COVID-19 symptom severity and need for hospitalization, few studies examine time to resolution of symptoms and potential complementary and alternative therapies that may expedite outpatient recovery. Uncertainty in expected symptom duration and potential missed opportunities to decrease this time persist. Likewise, studies tracking outpatient COVID-19 experiences among marginalized communities are lacking.

Objective

To describe the impact of complex Tibetan herbal formula regimens on symptom duration among ambulatory patients with native SARS-CoV-2 infection.

Methods

This multi-center, cohort study assessed deidentified data from patients with laboratory-confirmed SARS-CoV-2 infection. The study assessed cases from March 12, 2020 to May 5, 2021 for which vaccinations were not available, and thus reflect native infections.

Intervention

Diagnoses were made via telemedicine by a traditional Tibetan medical physician, and herbal formulas were prescribed based on specific symptom presentation of COVID-19 using the personalized medicine approach integral to traditional Tibetan medicine.

Results

Of 145 patient cases assessed for eligibility, 86 (59.3%) met inclusion criteria, and 67 (46.2%) had documented symptom resolution. Resolution of symptoms occurred within a median [interquartile range (IQR)] of 11.7 (10.1–13.5) days. The most common symptoms reported were cough and fever. Time to recovery did not significantly differ based on symptom presentation at baseline, except for a couple symptom groupings such as headache and joint pain where recovery time was shorter when those symptoms were present.

Conclusions and relevance

Ambulatory patients diagnosed with SARS-CoV-2 infection receiving Tibetan herbal formulas had recovery from symptoms at a median of 11.7 days, fewer than other published reports in patients following standard of care. The Tibetan approach of targeting treatment based on symptom groups, especially those within classical Tibetan medical nosology, appears to result in quick symptom resolution.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信