Traditional Chinese medicine research on attention deficit hyperactivity disorder: Theory, treatment and mechanism

Brain Behavior and Immunity Integrative Pub Date : 2024-01-01 DOI:10.1016/j.bbii.2024.100049

Congxiao Zhou , Junhong Wang

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Abstract

Attention deficit hyperactivity disorder (ADHD) is a complex neurodevelopmental disorder that affects a significant number of children and adults worldwide. Traditional Chinese medicine (TCM) has shown promising results in the treatment of ADHD, serving as an important complementary therapy alongside conventional approaches. This review aims to provide a comprehensive understanding of the theoretical foundations, treatment modalities, and underlying mechanisms of TCM in the management of ADHD. The concept of ADHD from a TCM perspective emphasizes on the role of imbalances in yin and yang. The treatment encompasses pattern identification, common patterns, pharmacological and non-pharmacological interventions, as well as relevant clinical trials. For mechanism, this review explores the impact of TCM compound formulas on neuroimmunology and neurotransmitters, highlighting the potential modulation of microglia, cytokines, dopamine, norepinephrine, and serotonin.

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注意缺陷多动障碍的中医药研究：理论、治疗和机制

注意缺陷多动障碍（ADHD）是一种复杂的神经发育障碍，影响着全球众多儿童和成年人。传统中医药（TCM）在治疗注意力缺陷多动障碍（ADHD）方面取得了可喜的成果，成为传统疗法的重要补充疗法。本综述旨在全面了解中医药治疗多动症的理论基础、治疗方式和内在机制。中医多动症的概念强调阴阳失衡的作用。治疗方法包括辨证论治、常见证型、药物和非药物干预以及相关临床试验。在机理方面，本综述探讨了中药复方对神经免疫学和神经递质的影响，强调了对小胶质细胞、细胞因子、多巴胺、去甲肾上腺素和血清素的潜在调节作用。

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Brain Behavior and Immunity Integrative

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