Biomedical Technology最新文献_第6页

Applications of 3D printing in tumor treatment 3D打印在肿瘤治疗中的应用

Biomedical Technology Pub Date : 2023-05-02 DOI: 10.1016/j.bmt.2023.03.002

Jiante Li , Danna Liang , Xiang Chen , Weijian Sun , Xian Shen

引用次数: 1

Application of nucleic acid signal amplification in biosensing and bioimaging 核酸信号扩增在生物传感和生物成像中的应用

Biomedical Technology Pub Date : 2023-05-01 DOI: 10.1016/j.bmt.2023.03.004

Junqi Zhao , Xueqin Li , Dagan Zhang , Sen Wang

引用次数: 0

Overcoming melanoma resistance to immune checkpoint blockade therapy using nano-strategies 利用纳米策略克服黑色素瘤对免疫检查点阻断疗法的抵抗

Biomedical Technology Pub Date : 2023-04-01 DOI: 10.1016/j.bmt.2023.03.003

Yiqin Ding , Changyi Liu , Yilun Wu , Fanfan Fu

引用次数: 1

Precisely integrated contact lens: An intraocular pressure guard for glaucoma patients 精密集成隐形眼镜:青光眼患者的眼压保护装置

Biomedical Technology Pub Date : 2023-03-31 DOI: 10.1016/j.bmt.2023.03.001

Meixin Ran , Jiaqi Yan , Hongbo Zhang

引用次数: 0

Developing engineering technologies for the treatment of systemic lupus erythematosus 开发治疗系统性红斑狼疮的工程技术

Biomedical Technology Pub Date : 2023-03-22 DOI: 10.1016/j.bmt.2023.02.002

Xubin Hao , Yuze Wang , Rui Liu , Dagan Zhang , Bin Kong , Jun Liang , Lingyun Sun

{"title":"Developing engineering technologies for the treatment of systemic lupus erythematosus","authors":"Xubin Hao , Yuze Wang , Rui Liu , Dagan Zhang , Bin Kong , Jun Liang , Lingyun Sun","doi":"10.1016/j.bmt.2023.02.002","DOIUrl":"https://doi.org/10.1016/j.bmt.2023.02.002","url":null,"abstract":"<div><p>Systemic lupus erythematosus (SLE) is a complex autoimmune disease that affects multiple organs and tissues. However, only a handful of new drugs have been FDA-approved for SLE since the 1950s. Therefore, novel treatments for SLE are urgently needed to be developed. In recent years, various engineering technologies such as tissue engineering, organs-on-chips, and intelligent delivery systems have been rapidly developed in the field of biomedicine. Notably, engineered nanocarriers and cell-based therapies can address the problems faced by traditional drug delivery and cell transplantation. They have proven effective in the treatment of many areas of disease, including autoimmune diseases. This is an important opportunity to break through the limited treatment options for SLE. In this review, we summarize the application progresses of engineering technologies and also propose their challenges in SLE treatment. This paper aims to help readers to understand the perspective of engineering technologies on the direction of SLE treatments in forthcoming years.</p></div>","PeriodicalId":100180,"journal":{"name":"Biomedical Technology","volume":"4 ","pages":"Pages 1-10"},"PeriodicalIF":0.0,"publicationDate":"2023-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49709655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Exosomes-based particles as inhalable COVID-19 vaccines 基于外泌体的颗粒作为可吸入性COVID-19疫苗

Biomedical Technology Pub Date : 2023-03-22 DOI: 10.1016/j.bmt.2023.01.003

Lu Fan , Li Wang , Xiaoju Wang , Hongbo Zhang

{"title":"Exosomes-based particles as inhalable COVID-19 vaccines","authors":"Lu Fan , Li Wang , Xiaoju Wang , Hongbo Zhang","doi":"10.1016/j.bmt.2023.01.003","DOIUrl":"https://doi.org/10.1016/j.bmt.2023.01.003","url":null,"abstract":"<div><p>Coronavirus disease 2019 (COVID-19), a severely spreading pandemic, has dramatically brought physiological and economical burdens to people. Although the injectable vaccines have some achievements for coronavirus defense, they still generate accompanied pain, untoward reaction and cannot take part in mucosal immunity. Inhalable vaccines, as a safe, facile and efficient strategy, have been presented to protect body from virus by inducing robust mucosal immunity. Here, we give a perspective of an inhalable COVID-19 vaccine composed of lung-derived exosomes (a type of virus-like particle) conjugated with viral receptor-binding domain. The lung-derived exosomes act as carriers, such inhalable particles successfully reach at lung and reveal wider distribution and longer retention on respiratory mucosa. In addition, such vaccines induce the high production of specific antibodies and T cells in lung, significantly protecting host against coronavirus invasion. It is conceived that inhalable virus-like particles with long-term stability wound open a new avenue for vaccines delivery and further achieve vaccine popularization to against with COVID-19 pandemic.</p></div>","PeriodicalId":100180,"journal":{"name":"Biomedical Technology","volume":"4 ","pages":"Pages 24-27"},"PeriodicalIF":0.0,"publicationDate":"2023-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49709416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

A scientific debate: The sword that cleaves chaos of DNAzyme catalysis research 一场科学辩论:割裂DNAzyme催化研究混乱的利剑

Biomedical Technology Pub Date : 2023-03-22 DOI: 10.1016/j.bmt.2023.01.004

Jiaqi Yan , Meixin Ran , Hongbo Zhang

引用次数: 1

A comprehensive review on carbon quantum dots as an effective photosensitizer and drug delivery system for cancer treatment 碳量子点作为一种有效的光敏剂和给药系统用于癌症治疗的综述

Biomedical Technology Pub Date : 2023-03-22 DOI: 10.1016/j.bmt.2023.01.005

Kondi Soumya, Namdev More, Mounika Choppadandi, D.A. Aishwarya, Gajendar Singh, Govinda Kapusetti

引用次数: 9

Exploring the revolution in healthcare systems through the applications of digital twin technology 通过数字孪生技术的应用探索医疗保健系统的革命

Biomedical Technology Pub Date : 2023-03-22 DOI: 10.1016/j.bmt.2023.02.001

Abid Haleem , Mohd Javaid , Ravi Pratap Singh , Rajiv Suman

{"title":"Exploring the revolution in healthcare systems through the applications of digital twin technology","authors":"Abid Haleem , Mohd Javaid , Ravi Pratap Singh , Rajiv Suman","doi":"10.1016/j.bmt.2023.02.001","DOIUrl":"https://doi.org/10.1016/j.bmt.2023.02.001","url":null,"abstract":"<div><p>Digital Twin is a virtual replica of an item that is gaining traction in several sectors. This technology is creating significant advancements in the field of healthcare. A machine or a person's digital twin is a virtual replica of that entity. In order to create a digital model that can be tested and simulated, one has to gather enormous volumes of data through Internet of Things (IoT) sensors for the associated application. Based on the patient's lifestyle, regular eating habits, and blood sugar data, this technology helps to warn the patient about prescriptions, dietary adjustments, medical consultations, and other situations. Digital Twin uses a substantial quantity of data from multiple IoT devices and uses Artificial Intelligence (AI)-powered models. Patients' own Digital Twin uses previous data insights to help select the most appropriate medication, forecast the results of a particular surgery, and control chronic illness. The main aim of this paper is to study Digital Twin and its need for the healthcare sector. This Paper discusses various features and services of Digital Twin for Healthcare. Various technologies and tools of Digital Twins for Healthcare are also briefed and further identified and discussed, along with significant applications. The healthcare sector has realised to create a framework focused on the patient. In the future, healthcare should think about more advanced ways to provide best-in-class treatment to the patient. Planning for the post-digital era is crucial as healthcare organisations continue their digital transformation initiatives.</p></div>","PeriodicalId":100180,"journal":{"name":"Biomedical Technology","volume":"4 ","pages":"Pages 28-38"},"PeriodicalIF":0.0,"publicationDate":"2023-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49709408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 13

Ultrasound-responsive microparticles from droplet microfluidics 来自液滴微流体的超声响应微粒

Biomedical Technology Pub Date : 2023-03-01 DOI: 10.1016/j.bmt.2022.10.001

Danqing Huang, Jinglin Wang, Junyi Che, Baojie Wen, Wentao Kong

{"title":"Ultrasound-responsive microparticles from droplet microfluidics","authors":"Danqing Huang, Jinglin Wang, Junyi Che, Baojie Wen, Wentao Kong","doi":"10.1016/j.bmt.2022.10.001","DOIUrl":"https://doi.org/10.1016/j.bmt.2022.10.001","url":null,"abstract":"<div><p>Ultrasound (US)-responsive microparticles show broad potential in controlled drug delivery systems. Compare with the traditional micron-scale material fabrication methods, capillary microfluidic technology features superior advantages in large-scale production, batch-to-batch similarity, high encapsulation efficiency, low cost, and so on. The excellent maneuverability and customizability of the capillary microfluidic devices allow the production of microparticles with various functionalities and fine-tuned chemical compartments. Moreover, the flexible regulation of the particle size and core-shell ratio can be easily realized by modulating the capillary orifices and flow rates of microfluidic channels. In this review, we introduce the fabrication of US-responsive microparticles with specific core-shell structures via capillary microfluidic methods, from single emulsion to triple emulsions. Then, we address some particular examples, where the drug delivery and US-triggered cargo release capacity of these microfluidic microparticles are demonstrated. Finally, we conclude the advanced achievements of the US-responsive microfluidic microparticles, summarize the obstacles to the development of this interdisciplinary field, and prospect their future applications.</p></div>","PeriodicalId":100180,"journal":{"name":"Biomedical Technology","volume":"1 ","pages":"Pages 1-9"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49710112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1