Biomedical Technology最新文献_第6页

Biomaterials for cardiovascular diseases 治疗心血管疾病的生物材料

Biomedical Technology Pub Date : 2024-09-01 Epub Date: 2024-06-05 DOI: 10.1016/j.bmt.2024.05.001

Yongqi Huang , Ziqi Ding

引用次数: 0

Emerging strategies for the treatment of endometriosis 治疗子宫内膜异位症的新策略

Biomedical Technology Pub Date : 2024-09-01 Epub Date: 2024-08-29 DOI: 10.1016/j.bmt.2024.08.002

Qiong Chen , Jing Wang , Xiaoya Ding , Qingfei Zhang , Ping Duan

{"title":"Emerging strategies for the treatment of endometriosis","authors":"Qiong Chen , Jing Wang , Xiaoya Ding , Qingfei Zhang , Ping Duan","doi":"10.1016/j.bmt.2024.08.002","DOIUrl":"10.1016/j.bmt.2024.08.002","url":null,"abstract":"<div><p>Endometriosis is an estrogen-dependent disorder of the reproductive tract, affecting approximately 10 % of women. The symptoms of this condition are vague and not correlated with the disease's stage. These associated symptoms significantly impact women's overall well-being. The etiology of endometriosis remains inadequately understood, with coelomic metaplasia, lymphatic and vascular dissemination being regarded as additional hypotheses in addition to the retrograde menstruation theory. Endometriosis is primarily treated with drug therapy and surgical intervention, but the recurrence rate of symptoms after five years remains approximately 50 %. Therefore, the advancement of more effective and safe therapies for the treatment of endometriosis is of paramount importance. In this review, we introduce the utilization of photodynamic therapy, hyperthermia, gene therapy, immunotherapy, stem cell therapy, nanotechnology, and micron technology in the management of endometriosis. The objective is to provide novel research perspectives for therapeutic approaches and facilitate future clinical translation to enhance patient outcomes.</p></div>","PeriodicalId":100180,"journal":{"name":"Biomedical Technology","volume":"7 ","pages":"Pages 46-62"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949723X24000175/pdfft?md5=62b25ff0bb6b24e2e05534564539033a&pid=1-s2.0-S2949723X24000175-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142089407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Polyaryletherketones: Properties and applications in modern medicine 聚芳醚酮：特性及在现代医学中的应用

Biomedical Technology Pub Date : 2024-06-01 Epub Date: 2024-01-09 DOI: 10.1016/j.bmt.2023.11.002

Gregory Sacks , Veer Shah , Lilian Yao , Catherine Yan , Darshi Shah , Lorely Limeta , Vincent DeStefano

{"title":"Polyaryletherketones: Properties and applications in modern medicine","authors":"Gregory Sacks , Veer Shah , Lilian Yao , Catherine Yan , Darshi Shah , Lorely Limeta , Vincent DeStefano","doi":"10.1016/j.bmt.2023.11.002","DOIUrl":"https://doi.org/10.1016/j.bmt.2023.11.002","url":null,"abstract":"<div><p>Polyaryletherketones (PAEKs) are a family of durable, multifunctional, thermoplastic biopolymers. This article first provides necessary context and thorough information regarding the mechanical, physical, chemical, crystalline, and shape memory properties of PAEKs as well as critical details regarding manufacturing. Additionally, it provides an update on the clinical and biomedical uses of PAEKs by summarizing the most recent and groundbreaking applications of these thermopolymers. PAEKs have been used clinically in fields including orthopedics, craniofacial and cardiothoracic surgery, as well as cardiovascular and dental medicine. Other applications include tissue engineering, post-surgical antibiotic delivery, antimicrobial applications, anti-cancer drug delivery, and 3D printing. Of importance, PAEKs have comparable mechanical strength and elastic modulus to human bone, which enable PAEKs to serve as a viable alternative to metal-based implants. Given their remarkable properties, and ability to be specifically and rapidly manufactured through 3D printing, PAEKs will continue to be a subject of biomedical research and serve a vital role in medical applications.</p></div>","PeriodicalId":100180,"journal":{"name":"Biomedical Technology","volume":"6 ","pages":"Pages 75-89"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949723X23000673/pdfft?md5=741112a94bdd8f8660046b21062d8865&pid=1-s2.0-S2949723X23000673-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139399084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Corrigendum to “A computational model to assess the effectiveness of adhesive materials in restoration of crown-root fractures” [Biomed. Technol. 6 (2024) 1-8] 对 "评估牙冠-牙根断裂修复中粘合材料有效性的计算模型 "的更正 [Biomed.

Biomedical Technology Pub Date : 2024-06-01 Epub Date: 2024-04-04 DOI: 10.1016/j.bmt.2024.03.001

Amandeep Kaur , Shubham Gupta , Nitesh Tewari , Arnab Chanda

引用次数: 0

Erratum regarding missing Declaration of Competing Interest statements in previously published articles 关于以前发表的文章中缺少 "竞争利益声明 "的勘误

Biomedical Technology Pub Date : 2024-06-01 Epub Date: 2024-04-10 DOI: 10.1016/j.bmt.2024.04.001

引用次数: 0

A review on selenium nanoparticles and their biomedical applications 硒纳米粒子及其生物医学应用综述

Biomedical Technology Pub Date : 2024-06-01 Epub Date: 2023-12-29 DOI: 10.1016/j.bmt.2023.12.001

K.K. Karthik , Binoy Varghese Cheriyan , S. Rajeshkumar , Meenaloshini Gopalakrishnan

{"title":"A review on selenium nanoparticles and their biomedical applications","authors":"K.K. Karthik , Binoy Varghese Cheriyan , S. Rajeshkumar , Meenaloshini Gopalakrishnan","doi":"10.1016/j.bmt.2023.12.001","DOIUrl":"https://doi.org/10.1016/j.bmt.2023.12.001","url":null,"abstract":"<div><p>Nanotechnology has enormous promise for a wide range of applications in biology. Nanoparticles (NPs) have the benefit of improving bioactivity, decreasing toxicity, allowing for precision targeting, and modulating the release profile of encapsulated compounds. Nanomaterials' unique qualities, such as their tiny size, biocompatibility, and ability to cross cell membranes for drug administration, make them useful in a variety of biological applications. Selenium (Se), a critical trace element, stands out among these nanoparticles due to its specific bioactivities in nano forms. Selenium is incorporated into Selenoproteins such as selenocysteine (Sec), which play an important role in maintaining physiological redox balance via oxidoreductase activity, a critical enzymatic process. In the field of medication delivery, selenium-based devices have been designed to transport pharmaceuticals to specific locations. Selenium nanoparticles (SeNPs) appear to be a suitable platform for delivering medications to their desired sites. Selenium's medicinal potential has been thoroughly investigated, including its efficacy against various cancer cells, microbial pathogens, viral infections, neuroprotective properties, diabetic control, oxidative stress, and inflammation-mediated illnesses such as rheumatoid arthritis. Notably, due to selenium's extraordinary involvement in immune system regulation, SeNPs have an edge over other nanoparticles. SeNPs phytosynthesis offers an appealing alternative to standard physical and chemical processes, featuring biocompatibility and environmental friendliness. This paper gives an overview of SeNPs' biological uses and emphasizes recent advances in the field.</p></div>","PeriodicalId":100180,"journal":{"name":"Biomedical Technology","volume":"6 ","pages":"Pages 61-74"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949723X23000764/pdfft?md5=a445391da4c23dcea4c119151b5d864c&pid=1-s2.0-S2949723X23000764-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139100875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bio-inspired hierarchical particles for bioassays 用于生物分析的仿生分层粒子

Biomedical Technology Pub Date : 2024-06-01 Epub Date: 2023-11-08 DOI: 10.1016/j.bmt.2023.09.003

Ning Li , Hanxu Chen , Dongyu Xu , Yuanjin Zhao

{"title":"Bio-inspired hierarchical particles for bioassays","authors":"Ning Li , Hanxu Chen , Dongyu Xu , Yuanjin Zhao","doi":"10.1016/j.bmt.2023.09.003","DOIUrl":"https://doi.org/10.1016/j.bmt.2023.09.003","url":null,"abstract":"<div><p>Bioassay technology has been proved important in the field of environmental monitoring, disease diagnosis and clinical treatment. At present, diverse bioassay technologies have achieved reliability, rapid responsiveness, convenient operation, along with high sensitivity, and specificity. Among them, micro-nano structure particles-based bioassay will inevitably play an important role for future development. Especially, compared with typical solid, porous or hollow particles, hierarchical particles are featured with hierarchical configurations and considerable surface area, and thus have gained extensive research interest as ideal scaffolds for biological, medical and catalytic applications in biomedicine. In this review, we present the recent advances in bio-inspired hierarchical particles. After introducing a variety of hierarchical particles and their synthesis methods, we focus on their applications in multiple biological detections of different targets such as proteins, DNA, RNA, exosomes and cells. In addition, the highlighted applications of hierarchical particles in bioassays for clinical diagnosis are also summarized and prospected.</p></div>","PeriodicalId":100180,"journal":{"name":"Biomedical Technology","volume":"6 ","pages":"Pages 17-25"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949723X23000557/pdfft?md5=209b9046b798cf66e21ce001ba543aca&pid=1-s2.0-S2949723X23000557-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92073831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Application of gas molecules in cancer therapy 气体分子在癌症治疗中的应用

Biomedical Technology Pub Date : 2024-06-01 Epub Date: 2023-12-08 DOI: 10.1016/j.bmt.2023.11.001

Danna Liang , Qingfei Zhang , Xiang Chen , Jianhua Lu , Xian Shen , Weijian Sun

{"title":"Application of gas molecules in cancer therapy","authors":"Danna Liang , Qingfei Zhang , Xiang Chen , Jianhua Lu , Xian Shen , Weijian Sun","doi":"10.1016/j.bmt.2023.11.001","DOIUrl":"https://doi.org/10.1016/j.bmt.2023.11.001","url":null,"abstract":"<div><p>Gas therapy is currently popular in cancer treatment because of its controllability, effectiveness, and biosafety, as well as the fast development of carriers for gas delivery. Here, we introduce the various gas molecules with exact anticancer effects, including nitric oxide (NO), carbon monoxide (CO), oxygen (O<sub>2</sub>), hydrogen (H<sub>2</sub>), etc., and their anticancer mechanisms. Besides, recent advances in stimuli-responsive delivery systems for gas therapy are summarized. In terms of the various stimulation methods, the design of delivery systems for gases is introduced. In addition, the strategies of gas therapy combined with other therapeutic modalities, including chemotherapy, radiotherapy (RT), photodynamic therapy (PDT), photothermal therapy (PTT), etc., are described. Finally, the current challenges and prospects of delivery platforms for gases, and the future development and clinical translational value of gas therapy are also discussed.</p></div>","PeriodicalId":100180,"journal":{"name":"Biomedical Technology","volume":"6 ","pages":"Pages 46-60"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949723X23000661/pdfft?md5=82a54cc81d7777d450c9d5f129f934b9&pid=1-s2.0-S2949723X23000661-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138557479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pitolisant nanofibers: A promising frontier in drug delivery for narcolepsy - Formulation, optimisation, and characterization insights 抗缩纳米纤维:治疗发作性睡病的前沿药物——配方、优化和特性分析

Biomedical Technology Pub Date : 2024-06-01 Epub Date: 2023-11-08 DOI: 10.1016/j.bmt.2023.10.002

J. Nandhini , E. Karthikeyan , C. Jegatheshwaran , K. Vignesh , G. Muthuboopathi , S. Rajeshkumar

{"title":"Pitolisant nanofibers: A promising frontier in drug delivery for narcolepsy - Formulation, optimisation, and characterization insights","authors":"J. Nandhini , E. Karthikeyan , C. Jegatheshwaran , K. Vignesh , G. Muthuboopathi , S. Rajeshkumar","doi":"10.1016/j.bmt.2023.10.002","DOIUrl":"https://doi.org/10.1016/j.bmt.2023.10.002","url":null,"abstract":"<div><p>The study focuses on developing a new way to deliver the narcolepsy medication pitolisant. Electrospinning was used to make polyvinyl alcohol (PVA) and hyperbranched polyglycerol (HPG) polymers into pitolisant nanofibers (PT-NF). A design expert created the best formulation to optimise the process variables like applied voltage, distance, and feed rate. The nanofibers were characterised using scanning electron microscopy, X-ray diffraction, FT-IR, entrapment efficiency, and in-vitro drug release studies. Results showed that the optimal PT-NF formulation had an average diameter of 172 nm with an entrapment efficacy of 95 % and 92 % drug release within 45 min. HPG polymer was included in the optimised formulation, whose average fibre diameter was 118 nm with 98 % entrapment efficacy and 98 ± 2 % drug release within 30 min. These findings strongly suggest that PT nanofibers hold substantial promise as a viable alternative to conventional solid dosage forms for brain-targeted administration, especially when administered via a transdermal patch to a patient during sleep.</p></div>","PeriodicalId":100180,"journal":{"name":"Biomedical Technology","volume":"6 ","pages":"Pages 9-16"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949723X23000570/pdfft?md5=fa1c5c35b3b72e011ee68bcd166f5ffc&pid=1-s2.0-S2949723X23000570-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92046601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nanomaterials for wound healing: Current status and futuristic frontier 纳米材料用于伤口愈合:现状与未来前沿

Biomedical Technology Pub Date : 2024-06-01 Epub Date: 2023-11-08 DOI: 10.1016/j.bmt.2023.10.001

J. Nandhini , E. Karthikeyan , S. Rajeshkumar

{"title":"Nanomaterials for wound healing: Current status and futuristic frontier","authors":"J. Nandhini , E. Karthikeyan , S. Rajeshkumar","doi":"10.1016/j.bmt.2023.10.001","DOIUrl":"https://doi.org/10.1016/j.bmt.2023.10.001","url":null,"abstract":"<div><p>Wound healing is a complex process that involves a variety of physical, chemical, and biological processes. Because of their remarkable characteristics and capabilities, nanomaterials have recently emerged as potential therapeutic agents for wound healing. Many different nanomaterial-based wound-healing treatments have been created and put into widespread use. In this review, we compile the most recent research on cutting-edge nanomaterials for wound healing, including both organic and inorganic nanomaterials. We highlight prospective approaches for developing nanomaterial-based wound healing therapy procedures and talk about the benefits and limitations of these treatments. Future prospects for wound healing therapies based on nanomaterials are discussed, including the need to address toxicity concerns, the scalability of production, and the long-term stability of nanomaterials. The safety and effectiveness of nanomaterials depend on further investigation into their design, interactions with biological systems, and the results of rigorous preclinical and clinical trials. There is great potential for a dramatic improvement in patient outcomes with the introduction of nanomaterial-based wound healing therapies.</p></div>","PeriodicalId":100180,"journal":{"name":"Biomedical Technology","volume":"6 ","pages":"Pages 26-45"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949723X23000569/pdfft?md5=c7e7bfb4a63f383dc74e52635f35aea9&pid=1-s2.0-S2949723X23000569-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92066691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0