Biomedical Technology最新文献_第6页

A scientific debate: The sword that cleaves chaos of DNAzyme catalysis research 一场科学辩论:割裂DNAzyme催化研究混乱的利剑

Biomedical Technology Pub Date : 2023-03-22 DOI: 10.1016/j.bmt.2023.01.004

Jiaqi Yan , Meixin Ran , Hongbo Zhang

引用次数: 1

A comprehensive review on carbon quantum dots as an effective photosensitizer and drug delivery system for cancer treatment 碳量子点作为一种有效的光敏剂和给药系统用于癌症治疗的综述

Biomedical Technology Pub Date : 2023-03-22 DOI: 10.1016/j.bmt.2023.01.005

Kondi Soumya, Namdev More, Mounika Choppadandi, D.A. Aishwarya, Gajendar Singh, Govinda Kapusetti

引用次数: 9

Exploring the revolution in healthcare systems through the applications of digital twin technology 通过数字孪生技术的应用探索医疗保健系统的革命

Biomedical Technology Pub Date : 2023-03-22 DOI: 10.1016/j.bmt.2023.02.001

Abid Haleem , Mohd Javaid , Ravi Pratap Singh , Rajiv Suman

{"title":"Exploring the revolution in healthcare systems through the applications of digital twin technology","authors":"Abid Haleem , Mohd Javaid , Ravi Pratap Singh , Rajiv Suman","doi":"10.1016/j.bmt.2023.02.001","DOIUrl":"https://doi.org/10.1016/j.bmt.2023.02.001","url":null,"abstract":"<div><p>Digital Twin is a virtual replica of an item that is gaining traction in several sectors. This technology is creating significant advancements in the field of healthcare. A machine or a person's digital twin is a virtual replica of that entity. In order to create a digital model that can be tested and simulated, one has to gather enormous volumes of data through Internet of Things (IoT) sensors for the associated application. Based on the patient's lifestyle, regular eating habits, and blood sugar data, this technology helps to warn the patient about prescriptions, dietary adjustments, medical consultations, and other situations. Digital Twin uses a substantial quantity of data from multiple IoT devices and uses Artificial Intelligence (AI)-powered models. Patients' own Digital Twin uses previous data insights to help select the most appropriate medication, forecast the results of a particular surgery, and control chronic illness. The main aim of this paper is to study Digital Twin and its need for the healthcare sector. This Paper discusses various features and services of Digital Twin for Healthcare. Various technologies and tools of Digital Twins for Healthcare are also briefed and further identified and discussed, along with significant applications. The healthcare sector has realised to create a framework focused on the patient. In the future, healthcare should think about more advanced ways to provide best-in-class treatment to the patient. Planning for the post-digital era is crucial as healthcare organisations continue their digital transformation initiatives.</p></div>","PeriodicalId":100180,"journal":{"name":"Biomedical Technology","volume":"4 ","pages":"Pages 28-38"},"PeriodicalIF":0.0,"publicationDate":"2023-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49709408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 13

Ultrasound-responsive microparticles from droplet microfluidics 来自液滴微流体的超声响应微粒

Biomedical Technology Pub Date : 2023-03-01 DOI: 10.1016/j.bmt.2022.10.001

Danqing Huang, Jinglin Wang, Junyi Che, Baojie Wen, Wentao Kong

{"title":"Ultrasound-responsive microparticles from droplet microfluidics","authors":"Danqing Huang, Jinglin Wang, Junyi Che, Baojie Wen, Wentao Kong","doi":"10.1016/j.bmt.2022.10.001","DOIUrl":"https://doi.org/10.1016/j.bmt.2022.10.001","url":null,"abstract":"<div><p>Ultrasound (US)-responsive microparticles show broad potential in controlled drug delivery systems. Compare with the traditional micron-scale material fabrication methods, capillary microfluidic technology features superior advantages in large-scale production, batch-to-batch similarity, high encapsulation efficiency, low cost, and so on. The excellent maneuverability and customizability of the capillary microfluidic devices allow the production of microparticles with various functionalities and fine-tuned chemical compartments. Moreover, the flexible regulation of the particle size and core-shell ratio can be easily realized by modulating the capillary orifices and flow rates of microfluidic channels. In this review, we introduce the fabrication of US-responsive microparticles with specific core-shell structures via capillary microfluidic methods, from single emulsion to triple emulsions. Then, we address some particular examples, where the drug delivery and US-triggered cargo release capacity of these microfluidic microparticles are demonstrated. Finally, we conclude the advanced achievements of the US-responsive microfluidic microparticles, summarize the obstacles to the development of this interdisciplinary field, and prospect their future applications.</p></div>","PeriodicalId":100180,"journal":{"name":"Biomedical Technology","volume":"1 ","pages":"Pages 1-9"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49710112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Sustaining the healthcare systems through the conceptual of biomedical engineering: A study with recent and future potentials 通过生物医学工程概念维持医疗保健系统:一项具有近期和未来潜力的研究

Biomedical Technology Pub Date : 2023-03-01 DOI: 10.1016/j.bmt.2022.11.004

Mohd Javaid , Abid Haleem , Ravi Pratap Singh , Rajiv Suman

{"title":"Sustaining the healthcare systems through the conceptual of biomedical engineering: A study with recent and future potentials","authors":"Mohd Javaid , Abid Haleem , Ravi Pratap Singh , Rajiv Suman","doi":"10.1016/j.bmt.2022.11.004","DOIUrl":"https://doi.org/10.1016/j.bmt.2022.11.004","url":null,"abstract":"<div><p>Biomedical engineering is an interdisciplinary branch of engineering & technology that combines biomedical sciences with engineering principles. This discipline covers broad areas where biomedical engineers are involved in the fields of medicine, regenerative medicine & associated areas and in developing better products and services. Biomedical engineering offers software for simulation, 3D motion-catching and printing technologies for computer modelling and engineering. The discipline of biomedical engineering is a fast-moving, cross-disciplinary field covering medicine, biology, chemistry, engineering, nanotechnology and informatics. Innovative medical gadgets, vaccinations, disease control products, robotics, and algorithms that enhance human health worldwide are being developed by bioengineers. Living tissues are formed of bioactive cells and stored in regulated circumstances on biodegradable scaffolds. The use of biomedical engineering concepts is to address issues with healthcare. Biomedical engineers create medical tools and procedures that enhance people's health by combining their understanding of engineering, virology, and healthcare. Blood glucose monitoring, pacemakers, and prosthetic limbs are examples of biomedical equipment. The main purpose of this paper is to study Biomedical Engineering and its need in healthcare. The paper discusses various innovations and research aspects of Biomedical Engineering in the healthcare domain. The paper further identified and discussed significant applications of Biomedical engineering for healthcare. Biomedical engineering is a fascinating field of life science that can change healthcare and open the door to new technologies in prostheses, operating equipment, diagnoses, imaging and more. The multidisciplinary area of biomedical technology provides better possibilities for biological research and engineering and changes how we interact with the world.</p></div>","PeriodicalId":100180,"journal":{"name":"Biomedical Technology","volume":"1 ","pages":"Pages 39-47"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49761297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Screening and validation of prognostic indicator genes in the progression of HBV related hepatocellular carcinoma HBV相关肝细胞癌进展中预后指示基因的筛选和验证

Biomedical Technology Pub Date : 2023-03-01 DOI: 10.1016/j.bmt.2022.10.002

Jinglin Wang , Senzhe Xia , Yuyan Chen , Xueqian Qin , Shujun Liu , Haozhen Ren

{"title":"Screening and validation of prognostic indicator genes in the progression of HBV related hepatocellular carcinoma","authors":"Jinglin Wang , Senzhe Xia , Yuyan Chen , Xueqian Qin , Shujun Liu , Haozhen Ren","doi":"10.1016/j.bmt.2022.10.002","DOIUrl":"https://doi.org/10.1016/j.bmt.2022.10.002","url":null,"abstract":"<div><p>Hepatocellular carcinoma (HCC) is a rapidly progressing cancer and the main reason for cancer-related deaths. There are numerous risk factors for HCC, of which hepatitis B virus (HBV) infection is recognized as a high risk. HBV infection is accompanied by gene integration, and the liver has undergone the process of continuous and repeated damage and repair. However, predictive factors of HBV-related HCC are still limited, and the prognostic regulatory genes have not been fully elucidated. This study aims to use bioinformatics analysis to search potential prognostic genes of HBV-related HCC. Based on the full utilization of the GEO database, we screened out prognostic-related genes by performing systematic Kaplan-Meier survival analysis. The differences of the transcriptional information and protein expression were verified in the TCGA and HPA databases respectively, and the clinical characteristics of the screened genes were described by the boxplot. Five prognostic-related genes we screened, including CDK1, MAD2L1, SPP1, TYMS, and CCNA2, are strongly linked with poor prognosis in HBV-related HCC. The five prognostic-related genes have realistic clinical significance and potential as prognostic markers, and may provide new directions for basic research and clinical diagnosis.</p></div>","PeriodicalId":100180,"journal":{"name":"Biomedical Technology","volume":"1 ","pages":"Pages 10-17"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49761308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Transplanted brain organoids become mature and intelligent 移植的脑类器官变得成熟和智能

Biomedical Technology Pub Date : 2023-03-01 DOI: 10.1016/j.bmt.2022.11.006

Xiangyi Wu , Ye Xu , Guopu Chen , Qian Tan , Yujuan Zhu

引用次数: 0

Injectable hydrogel microspheres in cartilage repair 可注射水凝胶微球在软骨修复中的应用

Biomedical Technology Pub Date : 2023-03-01 DOI: 10.1016/j.bmt.2022.11.002

Feng Lin, Yihan Li, Wenguo Cui

{"title":"Injectable hydrogel microspheres in cartilage repair","authors":"Feng Lin, Yihan Li, Wenguo Cui","doi":"10.1016/j.bmt.2022.11.002","DOIUrl":"https://doi.org/10.1016/j.bmt.2022.11.002","url":null,"abstract":"<div><p>The key to regenerative medicine is in situ regeneration of lesion cells, so as to achieve lesion repair and regeneration. However, the complex environment of the joint cavity where cartilage is located leads to poor efficacy of traditional therapies to promote cartilage repair and regeneration. Development of hydrogel microspheres offers an attractive solution for regenerative medicine aimed at cartilage repair to address these limitations. Hydrogel microspheres have the potential of injectable and multi-functional transformation, which can effectively regulate the pathophysiological changes of cells and extracellular matrix at the site of cartilage injury. This review summarizes the application of various functional modified hydrogel microspheres in cartilage repair and regeneration. The common techniques and biomaterials used to prepare hydrogel microspheres are first briefly introduced. In particular, the microfluidic technology is highlighted in detail. Besides, the construction strategies of hydrogel microspheres with different functions and their mechanisms to promote cartilage repair and regeneration are further presented. Finally, the problems and challenges of hydrogel microspheres for cartilage repair are summarized.</p></div>","PeriodicalId":100180,"journal":{"name":"Biomedical Technology","volume":"1 ","pages":"Pages 18-29"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49710113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 15

Bio-inspired adhesive hydrogel for wound healing 用于伤口愈合的仿生粘合剂水凝胶

Biomedical Technology Pub Date : 2023-03-01 DOI: 10.1016/j.bmt.2022.11.009

Wenzhao Li , Yuandong Zheng , Weiran Pang , Puxiang Lai

{"title":"Bio-inspired adhesive hydrogel for wound healing","authors":"Wenzhao Li , Yuandong Zheng , Weiran Pang , Puxiang Lai","doi":"10.1016/j.bmt.2022.11.009","DOIUrl":"https://doi.org/10.1016/j.bmt.2022.11.009","url":null,"abstract":"<div><p>Wound healing introduces a series of interesting challenges in healthcare, such as open wounds, burn wounds, and chronic infection wounds. Hence more accurate and effective biomedical materials are expected, for which emerging hydrogels with unique and excellent properties have demonstrated great potential. When they are applied as wound dressings, tissue patches, plugging agent, drug carriers, and biosensors, <em>etc</em>., there are urgent requirements for adhesive capabilities. The existence of interfacial water, soft tissue and moving surfaces, safety, and harmlessness, however, constitutes major constraints for medical adhesive hydrogels. In nature, organisms often adhere through unique structures or specific chemical components, which stimulates inspirations for medical hydrogels to overcome the above challenges. In this review, we will classify adhesive hydrogels into glue-like adhesives and tape-like patches according to their form. First, this review will introduce the principles and design ideas of biomedical adhesive hydrogels. Then, as biomedical materials, the applications and effects of their interactions with organisms through adhesion will be summarized. Finally, this review will summarize the achievements, challenges, and future development of bio-inspired adhesive hydrogel towards wound healing.</p></div>","PeriodicalId":100180,"journal":{"name":"Biomedical Technology","volume":"1 ","pages":"Pages 65-72"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49710088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Microfluidics-derived microcarrier systems for oral delivery 口服给药用微流体衍生的微载体系统

Biomedical Technology Pub Date : 2023-03-01 DOI: 10.1016/j.bmt.2022.11.001

Lijun Cai , Ning Li , Yong Zhang , Hongcheng Gu , Yujuan Zhu

引用次数: 8