Biomedical Technology最新文献_第7页

Applications of 3D printing in tumor treatment 3D打印在肿瘤治疗中的应用

Biomedical Technology Pub Date : 2024-03-01 Epub Date: 2023-05-02 DOI: 10.1016/j.bmt.2023.03.002

Jiante Li , Danna Liang , Xiang Chen , Weijian Sun , Xian Shen

引用次数: 1

Exploring mitochondrial DNA content as a novel biomarker to improve embryo implantation potential: A review 探索线粒体DNA含量作为一种新的生物标志物，以提高胚胎着床潜力:综述

Biomedical Technology Pub Date : 2024-03-01 Epub Date: 2023-07-06 DOI: 10.1016/j.bmt.2023.06.001

Devon Dickson , Tao Tao , Wensheng Qin

{"title":"Exploring mitochondrial DNA content as a novel biomarker to improve embryo implantation potential: A review","authors":"Devon Dickson , Tao Tao , Wensheng Qin","doi":"10.1016/j.bmt.2023.06.001","DOIUrl":"https://doi.org/10.1016/j.bmt.2023.06.001","url":null,"abstract":"<div><p>According to the society of assisted reproductive technologies (SART), the top fertility clinics in North America have reported overall pregnancy rates of up to 50% in good prognosis patients. Although new techniques in advanced reproductive technologies have begun to emerge in the twenty-first century, including time-lapse monitoring of embryo development, analysis of metabolites in embryo culture media, and the use of artificial intelligence in morphometric embryo grading, currently chromosomal status obtained via pre-implantation genetic testing for aneuploidy (PGT-A) appears to be the most definitive in evaluating embryonic potential. Yet still, in most clinics, approximately 30% of euploid or chromosomally normal embryos fail to achieve a viable pregnancy resulting in stress and anxiety for patients, repeat cycles, and increased cost of treatment. Recent literature suggests that blastocysts with an increased mitochondrial DNA (mtDNA) ratio have greatly reduced implantation potential, however, there exists controversial studies which do not report a relationship. This review summarizes the current literature on utilizing mitochondrial DNA as a possible biomarker for embryo implantation, highlights the reasons for inconsistencies in some studies and suggests possible improvements to the study design of future mtDNA ratio research.</p></div>","PeriodicalId":100180,"journal":{"name":"Biomedical Technology","volume":"5 ","pages":"Pages 82-86"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49761119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Application of nucleic acid signal amplification in biosensing and bioimaging 核酸信号扩增在生物传感和生物成像中的应用

Biomedical Technology Pub Date : 2024-03-01 Epub Date: 2023-05-01 DOI: 10.1016/j.bmt.2023.03.004

Junqi Zhao , Xueqin Li , Dagan Zhang , Sen Wang

引用次数: 0

Multiscale polymeric fibers for drug delivery and tissue engineering 用于药物输送和组织工程的多尺度聚合物纤维

Biomedical Technology Pub Date : 2024-03-01 Epub Date: 2023-06-07 DOI: 10.1016/j.bmt.2023.05.001

Junnan Mu , Danni Luo , Wei Li , Yaping Ding

{"title":"Multiscale polymeric fibers for drug delivery and tissue engineering","authors":"Junnan Mu , Danni Luo , Wei Li , Yaping Ding","doi":"10.1016/j.bmt.2023.05.001","DOIUrl":"https://doi.org/10.1016/j.bmt.2023.05.001","url":null,"abstract":"<div><p>Owing to their superior capacity for building structures, polymeric fibers with diameters varying from a few nanometers to hundreds of microns have been explored in biomedical applications as drug carriers or tissue engineering scaffolds. Depending on the source materials, fabrication techniques, and post-treatments, both the fiber diameter and surface morphology, as well as mechanical features and the cell-fiber structure interactions can be thoroughly tuned. Although most techniques could produce fibers within a wide range of sizes, each type may have superior advantages in a certain range, which may highly relate to target biomedical fields. Therefore, to properly choose the optimal technique for specific fibers, a comprehensive review of the current fiber-producing techniques is indispensable. In the current review, several main fiber-producing techniques are summarized, compared, and discussed in detail regarding their dominant fiber size ranges, which were classified as nano (<1000 nm), micro (1 μm−100 μm) and macro (>100 μm). The principals, main parameters, and corresponding applications for each technique are reviewed, and the challenges and future perspectives are proposed. We believe this review is highly informative for novice researchers in this field.</p></div>","PeriodicalId":100180,"journal":{"name":"Biomedical Technology","volume":"5 ","pages":"Pages 60-72"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49715721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

A scientific debate: The sword that cleaves chaos of DNAzyme catalysis research 一场科学辩论:割裂DNAzyme催化研究混乱的利剑

Biomedical Technology Pub Date : 2023-12-01 Epub Date: 2023-03-22 DOI: 10.1016/j.bmt.2023.01.004

Jiaqi Yan , Meixin Ran , Hongbo Zhang

引用次数: 1

Exosomes-based particles as inhalable COVID-19 vaccines 基于外泌体的颗粒作为可吸入性COVID-19疫苗

Biomedical Technology Pub Date : 2023-12-01 Epub Date: 2023-03-22 DOI: 10.1016/j.bmt.2023.01.003

Lu Fan , Li Wang , Xiaoju Wang , Hongbo Zhang

{"title":"Exosomes-based particles as inhalable COVID-19 vaccines","authors":"Lu Fan , Li Wang , Xiaoju Wang , Hongbo Zhang","doi":"10.1016/j.bmt.2023.01.003","DOIUrl":"https://doi.org/10.1016/j.bmt.2023.01.003","url":null,"abstract":"<div><p>Coronavirus disease 2019 (COVID-19), a severely spreading pandemic, has dramatically brought physiological and economical burdens to people. Although the injectable vaccines have some achievements for coronavirus defense, they still generate accompanied pain, untoward reaction and cannot take part in mucosal immunity. Inhalable vaccines, as a safe, facile and efficient strategy, have been presented to protect body from virus by inducing robust mucosal immunity. Here, we give a perspective of an inhalable COVID-19 vaccine composed of lung-derived exosomes (a type of virus-like particle) conjugated with viral receptor-binding domain. The lung-derived exosomes act as carriers, such inhalable particles successfully reach at lung and reveal wider distribution and longer retention on respiratory mucosa. In addition, such vaccines induce the high production of specific antibodies and T cells in lung, significantly protecting host against coronavirus invasion. It is conceived that inhalable virus-like particles with long-term stability wound open a new avenue for vaccines delivery and further achieve vaccine popularization to against with COVID-19 pandemic.</p></div>","PeriodicalId":100180,"journal":{"name":"Biomedical Technology","volume":"4 ","pages":"Pages 24-27"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49709416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

A comprehensive review on carbon quantum dots as an effective photosensitizer and drug delivery system for cancer treatment 碳量子点作为一种有效的光敏剂和给药系统用于癌症治疗的综述

Biomedical Technology Pub Date : 2023-12-01 Epub Date: 2023-03-22 DOI: 10.1016/j.bmt.2023.01.005

Kondi Soumya, Namdev More, Mounika Choppadandi, D.A. Aishwarya, Gajendar Singh, Govinda Kapusetti

引用次数: 9

Exploring the revolution in healthcare systems through the applications of digital twin technology 通过数字孪生技术的应用探索医疗保健系统的革命

Biomedical Technology Pub Date : 2023-12-01 Epub Date: 2023-03-22 DOI: 10.1016/j.bmt.2023.02.001

Abid Haleem , Mohd Javaid , Ravi Pratap Singh , Rajiv Suman

{"title":"Exploring the revolution in healthcare systems through the applications of digital twin technology","authors":"Abid Haleem , Mohd Javaid , Ravi Pratap Singh , Rajiv Suman","doi":"10.1016/j.bmt.2023.02.001","DOIUrl":"https://doi.org/10.1016/j.bmt.2023.02.001","url":null,"abstract":"<div><p>Digital Twin is a virtual replica of an item that is gaining traction in several sectors. This technology is creating significant advancements in the field of healthcare. A machine or a person's digital twin is a virtual replica of that entity. In order to create a digital model that can be tested and simulated, one has to gather enormous volumes of data through Internet of Things (IoT) sensors for the associated application. Based on the patient's lifestyle, regular eating habits, and blood sugar data, this technology helps to warn the patient about prescriptions, dietary adjustments, medical consultations, and other situations. Digital Twin uses a substantial quantity of data from multiple IoT devices and uses Artificial Intelligence (AI)-powered models. Patients' own Digital Twin uses previous data insights to help select the most appropriate medication, forecast the results of a particular surgery, and control chronic illness. The main aim of this paper is to study Digital Twin and its need for the healthcare sector. This Paper discusses various features and services of Digital Twin for Healthcare. Various technologies and tools of Digital Twins for Healthcare are also briefed and further identified and discussed, along with significant applications. The healthcare sector has realised to create a framework focused on the patient. In the future, healthcare should think about more advanced ways to provide best-in-class treatment to the patient. Planning for the post-digital era is crucial as healthcare organisations continue their digital transformation initiatives.</p></div>","PeriodicalId":100180,"journal":{"name":"Biomedical Technology","volume":"4 ","pages":"Pages 28-38"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49709408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 13

Overcoming melanoma resistance to immune checkpoint blockade therapy using nano-strategies 利用纳米策略克服黑色素瘤对免疫检查点阻断疗法的抵抗

Biomedical Technology Pub Date : 2023-12-01 Epub Date: 2023-04-01 DOI: 10.1016/j.bmt.2023.03.003

Yiqin Ding , Changyi Liu , Yilun Wu , Fanfan Fu

引用次数: 1

A computational model to assess the effectiveness of adhesive materials in restoration of crown-root fractures 一种评估粘接材料在冠根骨折修复中的有效性的计算模型

Biomedical Technology Pub Date : 2023-09-29 DOI: 10.1016/j.bmt.2023.09.002

Amandeep Kaur , Shubham Gupta , Nitesh Tewari , Arnab Chanda

{"title":"A computational model to assess the effectiveness of adhesive materials in restoration of crown-root fractures","authors":"Amandeep Kaur , Shubham Gupta , Nitesh Tewari , Arnab Chanda","doi":"10.1016/j.bmt.2023.09.002","DOIUrl":"https://doi.org/10.1016/j.bmt.2023.09.002","url":null,"abstract":"<div><p>Fragment reattachment for crown root fractures has become a routinely employed treatment modality with the advancements in adhesive dentistry. Among the majority of documented dental trauma cases, this specific fracture type is one of the most prevalent and difficult fracture kinds. Due to its complexity, these fracture kinds are often not computationally modelled. Moreover, there is a lack of literature to understand the effect of different adhesive materials, used to re-attach this particular fracture, on traumatic injuries. In our work, 3D models of the permanent maxillary central incisor tooth were developed using cone beam computed tomography image of a patient. This model was systematically modified to represent a prominent crown root fracture and subsequently re-attached computationally using three different adhesives. A biting force and a traumatic load were applied, and the induced stresses were studied across the healthy and treated tooth models and compared for three different adhesives used for re-attachment of fractured fragments. Tooth reattached with resin adhesive performed better in all the loading conditions that were considered in the study as compared to flowable composite and resin cement.</p></div>","PeriodicalId":100180,"journal":{"name":"Biomedical Technology","volume":"6 ","pages":"Pages 1-8"},"PeriodicalIF":0.0,"publicationDate":"2023-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49720774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0