Avances en Diabetología最新文献_第9页

Impacto económico y sanitario de las hipoglucemias nocturnas asociadas al tratamiento de la diabetes mellitus tipo 2 con insulina glargina o insulina NPH 甘精胰岛素或NPH胰岛素治疗2型糖尿病相关夜间低血糖的经济和健康影响

Avances en Diabetología Pub Date : 2013-01-01 DOI: 10.1016/j.avdiab.2012.10.006

Carlos Rubio-Terrés , Fernando Álvarez Guisasola , Jorge Navarro Pérez , Elías Delgado Álvarez , Sharona Azriel Mira , Ana Magaña

{"title":"Impacto económico y sanitario de las hipoglucemias nocturnas asociadas al tratamiento de la diabetes mellitus tipo 2 con insulina glargina o insulina NPH","authors":"Carlos Rubio-Terrés , Fernando Álvarez Guisasola , Jorge Navarro Pérez , Elías Delgado Álvarez , Sharona Azriel Mira , Ana Magaña","doi":"10.1016/j.avdiab.2012.10.006","DOIUrl":"10.1016/j.avdiab.2012.10.006","url":null,"abstract":"<div><h3>Objective</h3><p>To estimate the health and economic impact in Spain of nocturnal hypoglycemia linked to the treatment of type2 diabetes with insulin glargine (IG) or NPH insulin, both administered before bedtime.</p></div><div><h3>Methods</h3><p>The current cost of severe and symptomatic nocturnal hypoglycemia and the savings for the National Health Service (NHS) as a result of the reduction in the rate of occurrence of nocturnal hypoglycemia was calculated in the hypothetical case that the treatment with NPH was partially replace by IG. The use of health resources in clinical practice and the annual cost of hypoglycemic events were estimated by an expert panel of primary care and hospital clinicians. The reduction in the rate of hypoglycemic events with IG versus NPH was obtained from a published meta-analysis.</p></div><div><h3>Results</h3><p>The annual cost of hypoglycemia was estimated at 1,121.98€ (518.90-1,990.19€) in the case of severe hypoglycemia, 473.85€ (243.22-733.82€) in case of symptomatic hypoglycemia with plasma glucose levels <36mg/dl, and 295.83€ (149.63-406.59€) with levels <70mg/dl. For an estimated replacement of NPH by IG of 4%, 7%, 10%, and 11% in four years, in Spain 6,772 hypoglycemic events would be avoided (487, 756, and 5,529, respectively, depending on its severity). The savings for the NHS would correspond to 1.6 million€ (ranging from €829,000 to 2.5 million€).</p></div><div><h3>Conclusions</h3><p>The treatment of diabetes type2 with IG (vs. NPH), both administered at bedtime, could reduce the rate of nocturnal hypoglycemia and the associated costs for the NHS.</p></div>","PeriodicalId":100152,"journal":{"name":"Avances en Diabetología","volume":"29 1","pages":"Pages 19-26"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.avdiab.2012.10.006","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79622870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Nueva insulina basal de acción ultralenta: insulina degludec 新型超快作用基础胰岛素:degludec胰岛素

Avances en Diabetología Pub Date : 2013-01-01 DOI: 10.1016/j.avdiab.2012.11.001

Rafael Simó

引用次数: 6

Posibles causas de la infrautilización de la infusión subcutánea continua de insulina en España 西班牙持续皮下胰岛素输注使用不足的可能原因

Avances en Diabetología Pub Date : 2013-01-01 DOI: 10.1016/j.avdiab.2012.11.002

Ignacio Conget , Marga Giménez , Francisco Javier Ampudia-Blasco

引用次数: 12

Obesidad e hipogonadismo en paciente con diabetes tipo 2 2型糖尿病患者的肥胖和性腺功能减退

Avances en Diabetología Pub Date : 2012-11-01 DOI: 10.1016/j.avdiab.2012.10.005

Daniel Cabo Navarro, Florentino Carral San Laureano, María del Carmen Ayala Ortega, Ana Isabel Jiménez Millán, Antonia Piñero Zaldivar, Concepción García Calzado

引用次数: 0

Actividad física y síndrome metabólico: Citius-Altius-Fortius 身体活动与代谢综合征:Citius-Altius-Fortius

Avances en Diabetología Pub Date : 2012-11-01 DOI: 10.1016/J.AVDIAB.2012.10.002

Miguel A. Aguirre-Urdaneta, Joselyn J. Rojas-Quintero, Marcos Lima-Martínez

引用次数: 7

Actividad física y síndrome metabólico: Citius-Altius-Fortius 身体活动与代谢综合征:Citius-Altius-Fortius

Avances en Diabetología Pub Date : 2012-11-01 DOI: 10.1016/j.avdiab.2012.10.002

Miguel A. Aguirre-Urdaneta , Joselyn J. Rojas-Quintero , Marcos M. Lima-Martínez

引用次数: 7

Efectividad y seguridad de un modelo protocolizado de control glucémico en el medio hospitalario 医院血糖控制规程模型的有效性和安全性

Avances en Diabetología Pub Date : 2012-11-01 DOI: 10.1016/j.avdiab.2012.10.003

Florentino Carral-San Laureano , Manuel Cayón Blanco , Gloria Baena Nieto , Isabel Torres Barea , Cristina López Tinoco , Manuel Aguilar Diosdado

{"title":"Efectividad y seguridad de un modelo protocolizado de control glucémico en el medio hospitalario","authors":"Florentino Carral-San Laureano , Manuel Cayón Blanco , Gloria Baena Nieto , Isabel Torres Barea , Cristina López Tinoco , Manuel Aguilar Diosdado","doi":"10.1016/j.avdiab.2012.10.003","DOIUrl":"10.1016/j.avdiab.2012.10.003","url":null,"abstract":"<div><h3>Objective</h3><p>To evaluate the effectiveness and safety of a glucose control protocol designed to manage patients with diabetes in hospital.</p></div><div><h3>Material and methods</h3><p>An interventional, prospective and open study was designed for patients with diabetes admitted in a conventional hospital setting. Patients were randomized to an intervention group (glucose control protocol) or to a control group (conventional treatment for diabetes). Blood glucose was performed every 48hours. The primary endpoint was to obtain a pre-prandial blood glucose between 80 and 180mg/dl, and the secondary endpoint was the absence of hypoglycemia.</p></div><div><h3>Results</h3><p>The study included a total of 104 patients (51.0% male), with a mean age of 67.8±9.2 years old, 13.7±10.2 years since onset of diabetes, and mean HbA1c of 7.8±1.5%. The patients in the intervention group showed a significant improvement in glucose control before all meals as well as in the 24hour mean compared to day 0 and with the control group. In the first week, patients achieved a mean blood glucose of 148.2±30.3mg/dl. The percentage of patients with blood glucose between 80 and 180mg/dl gradually increased, exceeding 50% of patients from day 4 for fasting blood glucose, day 5 for blood glucose before lunch, and day 7 for blood glucose before dinner. Seven patients (13.4%) had mild hypoglycemia in the intervention group, and nine (17.3%) in the control group (<em>P</em>=.817).</p></div><div><h3>Conclusions</h3><p>The use of a blood glucose control protocol in hospital settings is effective for improving metabolic control and to achieve the targets, with a low rate of associated hypoglycemia.</p></div>","PeriodicalId":100152,"journal":{"name":"Avances en Diabetología","volume":"28 6","pages":"Pages 136-143"},"PeriodicalIF":0.0,"publicationDate":"2012-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.avdiab.2012.10.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86878699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dieta hipoglucídica en el tratamiento de la diabetes tipo 2 低血糖饮食在治疗2型糖尿病中的作用

Avances en Diabetología Pub Date : 2012-11-01 DOI: 10.1016/j.avdiab.2012.10.004

Andreu Nubiola , Imma Remolins

{"title":"Dieta hipoglucídica en el tratamiento de la diabetes tipo 2","authors":"Andreu Nubiola , Imma Remolins","doi":"10.1016/j.avdiab.2012.10.004","DOIUrl":"10.1016/j.avdiab.2012.10.004","url":null,"abstract":"<div><p>The low carbohydrate diet was introduced in the 1960's, in the middle of the biggest controversies in the field of nutrition: Are fats or sugars primarily responsible for obesity and most cardiovascular risk factors that accompany it? The official academic stance opted for the former, ignoring any other option. However, in recent years different types of diets low in carbohydrates have been observed, which, due to their results and proven safety, have become very popular. The scientific world has finally shown interest in them. These diets achieve their goals, mainly due to its greater adherence, increased thermogenesis, increased satiety and postprandial hyperinsulinemia reduction. This would lead to a maintained weight reduction and improvement in several cardiovascular risk factors. However, most studies show a wide disparity in the carbohydrate content (5%-40%), thus it is necessary to specify and correctly define this type of diet, in order to serve as a basis for developing further studies. The greatest benefits of this diet have been documented in type 2 diabetes, particularly in the metabolic syndrome, polycystic ovary syndrome and non-alcoholic hepato-steatosis.</p></div>","PeriodicalId":100152,"journal":{"name":"Avances en Diabetología","volume":"28 6","pages":"Pages 131-135"},"PeriodicalIF":0.0,"publicationDate":"2012-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.avdiab.2012.10.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83260960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Son fiables los medidores de glucemia capilar 毛细血管血糖仪是可靠的

Avances en Diabetología Pub Date : 2012-09-01 DOI: 10.1016/J.AVDIAB.2012.09.003

María Luisa Ramírez de Arellano y Oñate, Dolores Montoya Martínez

引用次数: 6

Riesgos y beneficios del tratamiento de la hiperglucemia en el paciente hospitalizado no crítico 非危重住院患者高血糖治疗的风险和益处

Avances en Diabetología Pub Date : 2012-09-01 DOI: 10.1016/J.AVDIAB.2012.09.004

Marta Botella Serrano

引用次数: 0