{"title":"The effect of oral trehalose on inflammatory factors, oxidative stress, nutritional and clinical status in patients with head trauma at intensive care unit: A pilot, double-blind, controlled, randomized clinical trial","authors":"","doi":"10.1016/j.acci.2024.02.001","DOIUrl":"10.1016/j.acci.2024.02.001","url":null,"abstract":"<div><h3>Background</h3><p>Traumatic brain injury (TBI) is the most common cause of cognitive and behavioral deficits, disability, and mortality worldwide. Trehalose is a natural non-reducing disaccharide of glucose which its anti-inflammatory and anti-oxidative stress effects have been proven in past in vivo and in vitro studies. This study aims to evaluate the effect of oral trehalose on inflammatory biomarkers, oxidative stress indices and clinical outcomes in hospitalized traumatic brain injury patients.</p></div><div><h3>Methods</h3><p>Twenty participants with traumatic brain injury were randomly assigned to the intervention or control group in order to evaluate the effect of oral trehalose (30<!--> <span>g instead as a part of the daily carbohydrate of enteral feeding) or placebo groups (standard isocaloric hospital enteral feeding) using 12-day parallel study. Inflammatory and oxidative stress biomarkers such as interleukin-6 (IL-6), C-reactive protein (CRP), pro-oxidant-antioxidant balance (PAB), superoxide dismutase (SOD), glutathione (GSH), and malondialdehyde (MDA), clinical outcomes, including APACHE II, SOFA scores, NUTRIC score, GCS, ICU discharge time, mechanical ventilator duration, 28-day and 60-day mortality rate were measured at the beginning and end of the study.</span></p></div><div><h3>Results</h3><p>The trehalose intake could significantly improve CRP (mean change: −30<!--> <!-->±<!--> <!-->25<!--> <!-->mg/l, <em>P</em> <!-->˂<!--> <!-->0.001) and NUTRIC score (mean change: 0(−2,0), <em>P</em> <!-->=<!--> <!-->0.04). In addition, a marginally significant decrease in APACHE II score (mean change: −3<!--> <!-->±<!--> <!-->5, <em>P</em> <!-->=<!--> <!-->0.07) and 28-day mortality (0 vs. 30%; <em>P</em> <!-->=<!--> <!-->0.06, {NNT}<!--> <!-->=<!--> <!-->3) was observed. Moreover, among anthropometric indicators, only a marginally decrease in MAC (mean change: −0.5(−1,0) was shown. No considerable effect was observed on other biomarkers, anthropometric indices and clinical outcomes in the intervention group as well as the control group.</p></div><div><h3>Conclusion</h3><p>This trial provided some evidences that trehalose administration improved CRP and marginally improved some clinical outcomes, such as NUTRIC score and 28-day mortality in TBI patients in ICU.</p></div>","PeriodicalId":100016,"journal":{"name":"Acta Colombiana de Cuidado Intensivo","volume":"24 3","pages":"Pages 214-225"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140276544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Desmielinización osmótica extrapontina: reporte de caso","authors":"","doi":"10.1016/j.acci.2024.01.003","DOIUrl":"10.1016/j.acci.2024.01.003","url":null,"abstract":"<div><p>This is the case of a 29-year-old female patient with a history of adrenal insufficiency who voluntarily discontinued medical treatment. She was admitted due to general and neurological symptoms with severe hyponatremia. She received rapid sodium replacement and subsequently developed clinical symptoms compatible with osmotic demyelination syndrome with extrapontine involvement, an uncommon compromise in clinical practice. Despite medical management, the patient presented an unfavorable evolution until death. The pathophysiology, diagnosis and treatment of this entity are explained and the importance of the recommendations regarding sodium replacement in cases of severe hyponatremia is highlighted.</p></div>","PeriodicalId":100016,"journal":{"name":"Acta Colombiana de Cuidado Intensivo","volume":"24 3","pages":"Pages 285-289"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140090043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
John J. Sprockel , Anngie L. Murcia , María C. Díaz , Luisa F. Rios , Oscar I. Quirós , Jhon E. Parra
{"title":"Performance of APACHE II, SOFA, and CURB-65 for death prognosis in COVID-19 critical patients: A prospective cohort study","authors":"John J. Sprockel , Anngie L. Murcia , María C. Díaz , Luisa F. Rios , Oscar I. Quirós , Jhon E. Parra","doi":"10.1016/j.acci.2023.12.006","DOIUrl":"10.1016/j.acci.2023.12.006","url":null,"abstract":"<div><h3>Rationale</h3><p>The identification of patients with high risk of death makes individual decision making more efficient, optimizing resources and improving the quality of the medical attention. The prognostic utility of APACHE II, SOFA, and CURB-65 in critical COVID-19 has not yet been determined.</p></div><div><h3>Objective</h3><p>The present work intends to validate these scoring systems for the prediction of death within 60 days in patients hospitalized in intensive care with COVID-19.</p></div><div><h3>Methods</h3><p>A prospective cohort was conducted which included adults with confirmed COVID-19 hospitalized in ICU. The scores were calculated by building ROC curves and calculating the areas under the curve and the curves of decision analysis.</p></div><div><h3>Measurements</h3><p>The operating characteristics and Kaplan Meier curves were calculated.</p></div><div><h3>Results</h3><p>320 patients between July and December 2020 were included, mortality within 60 days was 49.7%. CURB-65 had an AUC of 0.68 (CI 0.62–0.74), sensitivity 73.6%, and specificity 55.9%; APACHE-II had an AUC of 0.65 (CI 0.60–0.71), sensitivity 51.6%, and specificity 70.2%; and SOFA had an AUC of 0.70 (CI 0.64–0.75), sensitivity 83.6%, and specificity 52.2%. The three scoring systems obtained values of <em>p</em> <!--><<!--> <!-->0.001 for the LongRank test in the survival curves, offering moderate increments in the net benefit.</p></div><div><h3>Conclusion</h3><p>The scoring systems for clinical prediction CURB-65, APACHE II, and SOFA exhibited moderate discriminatory ability for death within 60 days in patients with COVID-19 hospitalized in intensive care; for the optimal cut-off level, there was an adequate power of discrimination.</p></div>","PeriodicalId":100016,"journal":{"name":"Acta Colombiana de Cuidado Intensivo","volume":"24 2","pages":"Pages 98-105"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139638249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Carlos Augusto Celemin Florez, Noé Muñoz Viveros, Maria del Mar Chavarro Moreno, Laura Angelica Rincón Palechor, Jose Yesid Medina Noscue, Dager Santiago Dorado Castañeda
{"title":"Rendimiento diagnóstico de la escala BROC2ULIS-65 comparada con CURB-65 en pacientes hospitalizados por neumonía","authors":"Carlos Augusto Celemin Florez, Noé Muñoz Viveros, Maria del Mar Chavarro Moreno, Laura Angelica Rincón Palechor, Jose Yesid Medina Noscue, Dager Santiago Dorado Castañeda","doi":"10.1016/j.acci.2023.12.009","DOIUrl":"10.1016/j.acci.2023.12.009","url":null,"abstract":"<div><p>Community-acquired pneumonia (CAP) is one of the most common and potentially fatal infectious diseases in daily practice. 40% of patients require admission to hospitalization and 5% of these require admission to the intensive care unit.</p></div><div><h3>Methods</h3><p>A cross-sectional retrospective cohort study was carried out, of patients treated between 2018 and 2022 for community-acquired pneumonia (CAP) at the Hospital Departamental San Antonio de Padua, including 241 patients in whom their mortality outcome was known.</p></div><div><h3>Statistical analysis</h3><p>They were analyzed with the statistical package STATA 17.0, the BROC2ULIS-65 index was constructed and compared with the CURB-65 standard and lactate for the measurement of CAP severity. Finally, an analysis of the area under the receiver operating characteristic curve (ACOR) was performed, calculating a 95% confidence interval. The Helsinki ethical recommendations and resolution 8430 of 1993 for research in humans were followed, as well as the confidentiality and protection of data.</p></div><div><h3>Results</h3><p>Of the 241 patients included in the final analysis, 56.02% were male, 56.85% of the patients were older than 65<!--> <!-->years, with a mean age of 65.65<!--> <!-->years (16.84), the minimum of 20<!--> <!-->years and the maximum of 96<!--> <!-->years. Both risk scores (BROC2ULIS-65 and CURB-65) showed statistically significant differences with <em>P</em> <!-->=<!--> <!-->.001 between patients with CAP who died and those who did not. After performing a Spearman correlation test, it was found that there was a significant linear correlation (<em>P</em> <!-->=<!--> <!-->.001) between the BROC2ULIS-65 value and the CURB-65. The BROC2ULIS-65 score equal to or greater than<!--> <!-->6 correctly classified 70.54% of patients with a specificity of 87.79% and a positive likelihood ratio (LR+) of 2.25.</p></div><div><h3>Conclusions</h3><p>The BROC2ULIS-65 scale with a score greater than or equal to<!--> <!-->6 correctly classified 70.54% of the patients with a specificity of 87.79% and a LR+ of 2.25; with AUC 0.638 compared to 0.635 of the CURB-65, respectively.</p></div>","PeriodicalId":100016,"journal":{"name":"Acta Colombiana de Cuidado Intensivo","volume":"24 2","pages":"Pages 106-113"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139632898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gilmer O. Pérez , Lía J. Jiménez Ramírez , Yeni A. Arroyave , Héctor F. Londoño
{"title":"Traqueostomías abiertas y percutáneas en un nivel iii de atención. Estudio de corte transversal","authors":"Gilmer O. Pérez , Lía J. Jiménez Ramírez , Yeni A. Arroyave , Héctor F. Londoño","doi":"10.1016/j.acci.2023.12.011","DOIUrl":"10.1016/j.acci.2023.12.011","url":null,"abstract":"<div><h3>Introduction</h3><p>There are 2<!--> <!-->types of tracheostomy: open (OT) and percutaneous (PT). There is no consensus on the technique of choice for the majority of patients, it is necessary to carry out studies on the clinical results with the use of the 2<!--> <!-->techniques.</p></div><div><h3>Objective</h3><p>Compare the clinical results in patients undergoing OT and PT in the intensive care unit of Hospital Universitario San José, Colombia between 2013 and 2018.</p></div><div><h3>Methods</h3><p>Observational cross-sectional study. A descriptive analysis was made and later both techniques were compared using Pearson's χ<sup>2</sup> test for qualitative variables and the Mann-Whitney <em>U</em> test for quantitative ones.</p></div><div><h3>Results</h3><p>Three hundred and sixty-two patients were included, most underwent PT corresponding to 53.87%. Both groups were similar with respect to clinical and sociodemographic characteristics. The BMI was lower for the TP (<em>P</em> = 0.001). The length of stay in the ICU did not differ, with a median of 19 and 17 for patients with OT and PT, respectively (<em>P</em> = 0.287). Only surgeons performed OT and in PT 35.38% were anesthesiologists, 32.82% surgeons and 32.31% intensivists. The most frequent complication was bleeding, followed by infection, although without a statistically significant difference. Overall mortality of 34.8%, with 0.83% secondary to the procedure.</p></div><div><h3>Conclusions</h3><p>Both surgeries proved to be safe, with a similar prevalence in terms of complications. PT can be performed by different professionals, without increasing complications. There was a difference in decannulation time, this item should be expanded in future research.</p></div>","PeriodicalId":100016,"journal":{"name":"Acta Colombiana de Cuidado Intensivo","volume":"24 2","pages":"Pages 124-130"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140090093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andrés Felipe Naranjo Ramírez , Álvaro de Jesús Medrano Areiza , Bryan Arango Sánchez , Juan Carlos Arango Martínez , Luis Fermín Naranjo Atehortúa
{"title":"Manejo postoperatorio de resección de tumores cerebrales en la unidad de cuidado intensivo","authors":"Andrés Felipe Naranjo Ramírez , Álvaro de Jesús Medrano Areiza , Bryan Arango Sánchez , Juan Carlos Arango Martínez , Luis Fermín Naranjo Atehortúa","doi":"10.1016/j.acci.2023.08.005","DOIUrl":"10.1016/j.acci.2023.08.005","url":null,"abstract":"<div><p>Neurosurgical procedures are considered major surgeries with potential complications that can be fatal or disabling, so postoperative care must be strict and systematic. Although it has always been believed that the care of these surgeries should be in the intensive care unit, the current trend has changed, making it possible to better select those patients who require monitoring in high dependency units. One of the main objectives in the postoperative care of patients undergoing elective craniectomy for brain tumors is maintaining homeostasis to promote recovery and reduce brain damage secondary to surgical trauma, in addition to quickly identifying neurological deterioration to carry out therapeutic behaviors that make it possible to establish immediate adequate medical treatment and communication with neurosurgery in the event that complications of a surgical nature that require reoperation are identified. Clinical evaluation and close follow-up take precedence over requesting diagnostic images, since serious complications will compromise the patient's neurological status. The implementation of enhanced recovery after surgery protocols to improve postoperative results, reduce hospital stay, costs and promote rehabilitation has become one of the most outstanding strategies in recent years for the care of neurosurgical patients. Multidisciplinary work must be the basis for achieving all the care and recovery objectives of the most complex patients admitted to the intensive care unit.</p></div>","PeriodicalId":100016,"journal":{"name":"Acta Colombiana de Cuidado Intensivo","volume":"24 2","pages":"Pages 140-151"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135347047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Helena Camino-Ferró, Enrique Chicote-Álvarez, Lucía Vilella-Llop, Isabel Mainar-Gil, Mirian Ruiz de la Cuesta-López, María Fuster-Cabré, Marlene Feo-González
{"title":"Neumonía hemorrágica por Stenotrophomonas maltophilia. Presentación de caso y revisión de la literatura","authors":"Helena Camino-Ferró, Enrique Chicote-Álvarez, Lucía Vilella-Llop, Isabel Mainar-Gil, Mirian Ruiz de la Cuesta-López, María Fuster-Cabré, Marlene Feo-González","doi":"10.1016/j.acci.2024.01.005","DOIUrl":"10.1016/j.acci.2024.01.005","url":null,"abstract":"<div><p>Hemorrhagic pneumonia caused by <em>Stenotrophomonas maltophilia</em> (SM) is a rare disorder, but its importance lies in the severity, rapid progression, and high mortality of this presentation, specially in immunocompromised patients, being severe neutropenia one of the main risk factors for this kind of pneumonia. Specifically, severity and rapid progression are the main characteristics that should make us suspect this disorder when a patient presents some of the risk factors; we should also start empirical antibiotic treatment if there is high suspicion. Here we display a case where a 56 year-old woman, diagnosed of multiple myeloma, and receiving chemotherapy, develops hemorrhagic pneumonia caused by SM, rapidly deteriorating in the first few hours.</p></div>","PeriodicalId":100016,"journal":{"name":"Acta Colombiana de Cuidado Intensivo","volume":"24 2","pages":"Pages 182-185"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140463751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bioética en pacientes renales crónicos avanzados con terapias de soporte renal sustitutivo: hemodiálisis, diálisis peritoneal y trasplantes","authors":"Rubén Dario Camargo Rubio","doi":"10.1016/j.acci.2023.08.001","DOIUrl":"10.1016/j.acci.2023.08.001","url":null,"abstract":"<div><p>Chronic kidney disease is a multifactorial process of a progressive and irreversible nature which frequently leads to a advanced state, and requires substitutive renal support therapies. The number of patients with end-stage renal disease is increasing worldwide, with an increasing demand for healthcare services. Being many of them candidates for palliative care, due to their chronic, advanced and life-limiting illness.</p><p>Patients and their families need to make early decisions for the end of life from the moment of diagnosis of the advanced illness, through the advance directive document, adequacy of the therapeutic effort and palliative care, a decision that will be based on adequate dialogic information that recognizes autonomy and respects the dignity and fundamental rights of the patient expressed through informed consent seeking the best good and quality of life.</p><p>Patients who opt for renal replacement support therapies know that their lives depend on the periodicity and compliance to hemodialysis, peritoneal dialysis or a successful kidney transplant, as well as the control of other pathologies associated with their disease. In order to know the bioethical aspects related to end-stage renal disease, a non-systematic review was carried out and rights, judgment values and proportionality for ethical decision-making were defined.</p><p>The objective was to know the bioethics in advanced chronic renal patients with renal replacement support therapies: hemodialysis, peritoneal dialysis and transplants.</p></div>","PeriodicalId":100016,"journal":{"name":"Acta Colombiana de Cuidado Intensivo","volume":"24 2","pages":"Pages 131-139"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134993817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Petra Zieher , Márcia Eliane Giuliato , Luana Turra , Mariane Carolina de Almeida , Sara Fernanda Hilgert , Antuani Rafael Baptistella
{"title":"Cancer patients admitted in the intensive care unit: Characteristics and outcomes","authors":"Petra Zieher , Márcia Eliane Giuliato , Luana Turra , Mariane Carolina de Almeida , Sara Fernanda Hilgert , Antuani Rafael Baptistella","doi":"10.1016/j.acci.2023.12.001","DOIUrl":"10.1016/j.acci.2023.12.001","url":null,"abstract":"<div><h3>Objective</h3><p>The aim of this study was to identify the profile of cancer patients admitted in the intensive care unit (ICU) and compares the outcomes with non-cancer patients hospitalized in the same period.</p></div><div><h3>Design</h3><p>This is a cross-sectional study.</p></div><div><h3>Setting</h3><p>Data were collected from medical records at Hospital Universitário Santa Terezinha, Joaçaba-SC, Brazil.</p></div><div><h3>Patients</h3><p>Admitted at ICU from April to November 2018.</p></div><div><h3>Interventions</h3><p>NA.</p></div><div><h3>Main variables of interest</h3><p>ICU outcomes.</p></div><div><h3>Results</h3><p><span>Of the 183 patients, 92 were cancer patients and 91 were non-cancer patients. There was a predominance of females for cancer and males for non-caner group, mostly elderly. Most hospitalizations of cancer patients were postoperative (49.4%). The cause of hospitalization of non-cancer patients was pneumonia, followed by traumatic brain injury, postoperative period, polytrauma, and septicemia. On the Sequential Organ Failure Assessment (SOFA) scale, cancer patients scored an average of 7.8 (±4.2) and on the Acute Physiology and Chronic Health </span>Disease Classification System (APACHE II) 13.3 points (±8.6), whereas non-cancer scored 7.6 (±3.55) and 20.9 points (±7.2), respectively. Non-cancer patients used more invasive mechanical ventilation and vasoactive drugs.</p></div><div><h3>Conclusion</h3><p>Cancer patients received less sedation and used less mechanical ventilation than non-cancer patients. In addition, cancer patients had a lower APACHE II score, denoting a less severe condition. Most surgical cancer patients demonstrate to benefit from intensive care, but it is still necessary to create more specific criteria for ICU admission.</p></div>","PeriodicalId":100016,"journal":{"name":"Acta Colombiana de Cuidado Intensivo","volume":"24 2","pages":"Pages 86-91"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139538186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Javier Polo Díaz , Luis Carbonell Riquett , Paola Blanco Pertuz , Diemer Muñoz Verbel , Amilkar Almanza Hurtado , Carmelo Dueñas Castell , Wilfrido Coronell Rodríguez
{"title":"Pericarditis purulenta por Staphylococcus aureus resistente a meticilina en un paciente con diálisis peritoneal: una afección cardíaca por una infección cutánea. Reporte de caso","authors":"Javier Polo Díaz , Luis Carbonell Riquett , Paola Blanco Pertuz , Diemer Muñoz Verbel , Amilkar Almanza Hurtado , Carmelo Dueñas Castell , Wilfrido Coronell Rodríguez","doi":"10.1016/j.acci.2023.12.007","DOIUrl":"10.1016/j.acci.2023.12.007","url":null,"abstract":"<div><p>Pericarditis is a relatively rare infectious/inflammatory condition observed in clinical hospital settings. The purulent pericarditis being the most uncommon manifestation and associated with the highest mortality rates. We detail the case of a 53-year-old male undergoing peritoneal-based renal replacement therapy who developed purulent pericarditis attributed to methicillin-resistant <em>Staphylococcus aureus</em> (MRSA), secondary to a skin and soft tissue source. This represents the first reported case with such features. Despite their rarity, such events carry a significant short-term mortality risk, emphasizing the importance of timely diagnosis. This manuscript aims to emphasize that despite its rarity, MRSA purulent pericarditis carries a significant risk of short-term mortality, hence the importance of timely diagnosis and treatment.</p></div>","PeriodicalId":100016,"journal":{"name":"Acta Colombiana de Cuidado Intensivo","volume":"24 2","pages":"Pages 177-181"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139634700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}