Trombocitopenia inmune asociada a dengue: una presentación poco habitual. Desafíos para los clínicos en brotes de dengue. Reporte de caso

Abstract

We present the case of a 59-year-old man, with no significant history, who presented with dengue without warning signs 25 days before entering the intensive care unit, due to presenting a clinical picture of severe thrombocytopenia of infectious origin secondary to dengue-type arbovirosis, confirmed by NS1 and IgM. He required management in the unit due to the risk of major bleeding, and corticosteroid pulses with favorable evolution given the early start of therapy. Dengue is a borne viral disease, primarily by the Aedes aegypti mosquito, that causes a wide range of symptoms, from high fever and muscle aches to life-threatening complications such as hemorrhagic shock and dengue shock syndrome. One of the most common complications of dengue is acute thrombocytopenia with resolution within 10 days of onset, but prolonged thrombocytopenia or immune thrombocytopenia has been seen in few patients. The objective of this publication is to give a general look at one of the complications of dengue that can be overlooked and severely complicate patients, since the limited current literature shows that an early start of management can lead to better clinical results and complete resolution of the condition.