ACS Publications最新文献_第6页

An Explicit Analytical Theory for Ignition Delay Time Prediction of Ammonia/Hydrogen Binary Carbon-Neutral Fuel

IF 3 2区化学

The Journal of Physical Chemistry A Pub Date : 2026-10-22 Epub Date: 2026-10-13 DOI: 10.1021/acs.jpca.6c03732

Jingqi Hu, Wenkai Liang

引用次数: 0

Discovery of LG-NE-29: An Orally Bioavailable GSPT1 Molecular Glue Degrader Effective in Glioblastoma Xenograft Models 一种口服生物可利用的GSPT1分子胶降解剂ln - ne -29的发现，对胶质母细胞瘤异种移植模型有效

IF 7.3 1区医学

Journal of Medicinal Chemistry Pub Date : 2026-10-22 Epub Date: 2026-10-03 DOI: 10.1021/acs.jmedchem.6c00544

Taiting Shi, Yuanyuan Pei, Bo Peng, Zerui Wu, Yixuan Feng, Yue Zhao, Yangyu Luo, Qi Chen, Songyan Chen, Jing Xu, Zhuang Shao, Yuhang Liu, Xueying Gong, Shuke Yang, Xiaoxiao Zou, Lixin Zhou, Yue Zhao, Hewei Jiang, Chunlong Xu, Zhanchao Meng, Wenchao Lu, Zhipeng Su

{"title":"Discovery of LG-NE-29: An Orally Bioavailable GSPT1 Molecular Glue Degrader Effective in Glioblastoma Xenograft Models","authors":"Taiting Shi, Yuanyuan Pei, Bo Peng, Zerui Wu, Yixuan Feng, Yue Zhao, Yangyu Luo, Qi Chen, Songyan Chen, Jing Xu, Zhuang Shao, Yuhang Liu, Xueying Gong, Shuke Yang, Xiaoxiao Zou, Lixin Zhou, Yue Zhao, Hewei Jiang, Chunlong Xu, Zhanchao Meng, Wenchao Lu, Zhipeng Su","doi":"10.1021/acs.jmedchem.6c00544","DOIUrl":"10.1021/acs.jmedchem.6c00544","url":null,"abstract":"The clinical management of glioblastoma (GBM) is severely hindered by rapid resistance to temozolomide (TMZ). Through viability-based phenotypic screening, we identified the translation termination factor GSPT1 (G1 to S phase transition 1) as a critical vulnerability in GBM cells. Structure−activity relationship optimization of an isoindolinone scaffold, specifically focused on improving metabolic stability, led to the discovery of LG-NE-29, a potent molecular glue degrader. This compound efficiently promotes CRBN-dependent ubiquitination and subsequent proteasomal degradation of GSPT1. LG-NE-29 overcomes the metabolic liabilities of early-generation scaffolds, exhibiting an optimized pharmacokinetic profile highlighted by excellent oral bioavailability (F = 76%). Mechanistically, GSPT1 depletion triggers a profound integrated stress response and intrinsic apoptosis. In U87MG xenograft models, oral administration of LG-NE-29 induced significant tumor regression. Collectively, these findings validate GSPT1 as an actionable therapeutic target in GBM and establish LG-NE-29 as a robust pharmacological tool for further targeted protein degradation research.","PeriodicalId":46,"journal":{"name":"Journal of Medicinal Chemistry","volume":"69 20","pages":"23540–23563"},"PeriodicalIF":7.3,"publicationDate":"2026-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149092153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Seeded-Surface Plasmonic Nanocavity with Enhanced Field Localization for Exciton–Plasmon Coupling 用于激子-等离子体耦合的增强场定位的种子表面等离子体纳米腔

IF 3.4 3区化学

The Journal of Physical Chemistry C Pub Date : 2026-10-22 Epub Date: 2026-10-12 DOI: 10.1021/acs.jpcc.6c03611

Lin Luo, Xin Shu, Xiaobo Han, Liang Ma, Xiaohong Li

{"title":"Seeded-Surface Plasmonic Nanocavity with Enhanced Field Localization for Exciton–Plasmon Coupling","authors":"Lin Luo, Xin Shu, Xiaobo Han, Liang Ma, Xiaohong Li","doi":"10.1021/acs.jpcc.6c03611","DOIUrl":"10.1021/acs.jpcc.6c03611","url":null,"abstract":"Achieving strong light–matter interaction in monolayertransitionmetal dichalcogenides (TMDCs) at room temperature requires plasmonicnanocavities with extreme field confinement and minimized mode volume.Although conventional nanoparticle-on-mirror (NPoM) cavities supportstrong gap-mode plasmon confinement, further compression of the electromagneticfield is desirable for enhancing exciton–plasmon interactionswith smaller excitonic ensembles. Here, we developed a seeded-surfaceNPoM (SS-NPoM) nanocavity consisting of a 50 nm Au nanocube decoratedwith 10 nm Au nanospheres, separated from an Au mirror by a 10 nmAl2O3 spacer and integrated with monolayer WS2. The surface nanoseeds introduce additional nanoscale protrusionsthat redistribute and compress the gap-plasmon field into highly localizedsubhotspots. Dark-field scattering measurements revealed a systematicdetuning-dependent anticrossing with mode splitting of 106 meV. Becausethis value is comparable to the stringent loss-based threshold, thesystem is conservatively classified as operating in an intermediate-couplingregime close to the onset of strong coupling. Quasinormal-mode calculationsshow that surface seeding can reduce the optical mode volume by 1order of magnitude, corresponding to an estimated minimum of ∼14coupled excitons in the most strongly confined configuration. Experimentally,the area-corrected photoluminescence enhancement reaches ∼690,compared with ∼220 for conventional NPoM cavities. These resultsdemonstrate that seeded-surface engineering provides an effectivestrategy for constructing highly localized plasmonic nanocavitiesand offers a promising platform for room-temperature TMDC polaritonicsand efficient nanoscale light sources.","PeriodicalId":61,"journal":{"name":"The Journal of Physical Chemistry C","volume":"130 42","pages":"14596–14601"},"PeriodicalIF":3.4,"publicationDate":"2026-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149152182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Weak Anion Hydration Drives LCST Behavior in Ionic Liquid–Water Mixtures: Insights from Calorimetry and Neutron Diffraction

IF 3.2 2区化学

The Journal of Physical Chemistry B Pub Date : 2026-10-22 Epub Date: 2026-10-11 DOI: 10.1021/acs.jpcb.6c04727

Sanskrita Madhukailya, Guillaume Depraetère, Nithavong Cam, Tristan G. A. Youngs, James P. Tellam, Margarida Costa Gomes, Leila Moura, John D. Holbrey

引用次数: 0

Coacervate Microreactors for Cholesterol-Coupled Nitric Oxide Biocatalysis in Atherosclerosis 用于动脉粥样硬化中胆固醇偶联一氧化氮生物催化的凝聚微反应器

IF 7.8 2区材料科学

ACS Applied Materials & Interfaces Pub Date : 2026-10-21 Epub Date: 2026-10-06 DOI: 10.1021/acsami.6c12847

Xinling Yao, Lin Yang, Jixiang Xiao, Haihong Yu, Xiuwen Zheng, Wenjing Li, Shaohong Zhou, Yanan Zeng, Hongyan Li, Zeren Ya, Zao Qiu, Peifeng Guo, Jiayan Zou, Songyang Liu

{"title":"Coacervate Microreactors for Cholesterol-Coupled Nitric Oxide Biocatalysis in Atherosclerosis","authors":"Xinling Yao, Lin Yang, Jixiang Xiao, Haihong Yu, Xiuwen Zheng, Wenjing Li, Shaohong Zhou, Yanan Zeng, Hongyan Li, Zeren Ya, Zao Qiu, Peifeng Guo, Jiayan Zou, Songyang Liu","doi":"10.1021/acsami.6c12847","DOIUrl":"10.1021/acsami.6c12847","url":null,"abstract":"Atherosclerosis is driven by metabolic dysregulation, particularly aberrant cholesterol accumulation and impaired nitric oxide (NO) signaling. However, most therapeutic strategies address these abnormalities separately, while biomaterials capable of translating pathological metabolic dysregulation into localized biochemical regulation remain limited. Herein, we report MMCoac@ChOx/HRP, a macrophage membrane-camouflaged coacervate microreactor formed via liquid–liquid phase separation (LLPS). The microreactor features a macromolecularly crowded core self-assembled from poly(diallyldimethylammonium chloride) and sulfobutylether-β-cyclodextrin, which enables cholesterol recognition and enrichment of cholesterol oxidase (ChOx) and horseradish peroxidase (HRP). These co-encapsulated enzymes achieve high enrichment efficiencies of 87.5 and 92.1%, respectively, to drive cholesterol oxidation and subsequent NO generation. In simulated body fluid, MMCoac@ChOx/HRP depleted cholesterol levels from 5.0 to 2.9 ± 0.4 mM and generated 12.1 ± 0.8 μM NO within 12 h. In vitro, it significantly attenuated macrophage foam cell formation and promoted endothelial repair. Furthermore, following systemic administration in ApoE–/– mice, MMCoac@ChOx/HRP preferentially accumulated in atherosclerotic aortic plaques, enhanced in situ NO generation, and reduced aortic plaque burden from 27.4 ± 4.5 to 8.2 ± 3.0%. Overall, this study demonstrates a localized metabolic intervention strategy driven by an LLPS-based microreactor. This versatile biomaterial platform effectively modulates the plaque microenvironment, holding great potential for therapeutic interventions against metabolic syndrome.","PeriodicalId":5,"journal":{"name":"ACS Applied Materials & Interfaces","volume":"18 41","pages":"55857–55873"},"PeriodicalIF":7.8,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149091619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enabling Efficient Ion Transport and Stable Interfaces of PEO-Based Solid Electrolytes via an I2/COF Charge-Transfer Complex 通过I2/COF电荷转移配合物实现高效离子传输和peo基固体电解质的稳定界面。

IF 7.8 2区材料科学

ACS Applied Materials & Interfaces Pub Date : 2026-10-21 Epub Date: 2026-10-06 DOI: 10.1021/acsami.6c15793

Jing Li, Yaping Sun, Bing Li, Cheng Lian, Haiping Su, Jingkun Li, Honglai Liu

{"title":"Enabling Efficient Ion Transport and Stable Interfaces of PEO-Based Solid Electrolytes via an I2/COF Charge-Transfer Complex","authors":"Jing Li, Yaping Sun, Bing Li, Cheng Lian, Haiping Su, Jingkun Li, Honglai Liu","doi":"10.1021/acsami.6c15793","DOIUrl":"10.1021/acsami.6c15793","url":null,"abstract":"Insufficient Li+ transport kinetics and poor interfacial stability hinder the practical application of polyethylene oxide (PEO)-based solid-state electrolytes (SSEs) in all-solid-state lithium metal batteries. In this work, we propose iodine-induced charge transfer of a covalent organic framework (COF) as an effective strategy to achieve fast ion transport and a stable SSE/Li interface. First, the electron-deficient COF skeleton in the I2/COF charge-transfer complex anchors TFSI- anions through enhanced electrostatic interactions, thereby promoting the dissociation of lithium salt to release free Li+. Second, the electron deficiency of COF strengthens its dipole–dipole interactions with PEO, leading to suppressed PEO crystallization and enhanced COF/PEO compatibility. Third, the electron-deficient COF tailors the Li+ coordination environment via weakening the affinity of PEO and COF toward Li+. Consequently, the I2/COF charge-transfer complex accelerates Li+ transport kinetics in PEO-based composite SSEs. Furthermore, the confinement effect of COF toward I2 via charge transfer effectively inhibits the aggressive lithium anode corrosion by I2, resulting in the controlled growth of a stable, robust, and conductive solid electrolyte interface (SEI) rich in LiF and LiI. Thus, the I2/COF charge-transfer complex enables excellent rate capability and cycling stability of the resulting COF/PEO-based composite SSE, maintaining a capacity retention of 88.58% after 1000 cycles at 2 C. This work offers a promising strategy for designing COF/PEO-based composite SSEs for next-generation all-solid-state lithium metal batteries.","PeriodicalId":5,"journal":{"name":"ACS Applied Materials & Interfaces","volume":"18 41","pages":"56182–56191"},"PeriodicalIF":7.8,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149100956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Constructing Molecular Bridging at the SnO2/Perovskite Interface for Efficient and Stable Perovskite Solar Cells 在SnO2/钙钛矿界面构建分子桥接用于高效稳定的钙钛矿太阳能电池。

IF 7.8 2区材料科学

ACS Applied Materials & Interfaces Pub Date : 2026-10-21 Epub Date: 2026-10-07 DOI: 10.1021/acsami.6c17670

Mengru Liu, Zhenlong Zhang, Huafang Zhang, Yuefeng Liu, Huiping Gao, Yanli Mao

{"title":"Constructing Molecular Bridging at the SnO2/Perovskite Interface for Efficient and Stable Perovskite Solar Cells","authors":"Mengru Liu, Zhenlong Zhang, Huafang Zhang, Yuefeng Liu, Huiping Gao, Yanli Mao","doi":"10.1021/acsami.6c17670","DOIUrl":"10.1021/acsami.6c17670","url":null,"abstract":"Interfacial quality at the SnO2 electron transport layer (ETL)/perovskite junction critically governs the electron collection and device performance in n-i-p type perovskite solar cells (PSCs). However, the defects within SnO2 and at the buried interface can impede electron extraction and promote charge recombination. Herein, cesium hexafluorophosphate (CsPF6) was introduced into the SnO2 precursor as an interfacial additive. Calculations and experimental measurements indicate that the F atoms of PF6– coordinate with undercoordinated Sn sites, whereas Cs participates in the formation of an FA-Cs alloyed layer at the buried perovskite surface. These interactions establish a molecular bridge across the SnO2/perovskite junction. The resulting bridge suppresses the interfacial defects, improves the energy-level alignment and physical contact, and regulates the perovskite crystallization. The devices incorporating CsPF6 deliver a champion power conversion efficiency (PCE) of 24.25%. They also show enhanced stability. The unencapsulated devices retain 90.05% of their initial PCE after 1000 h of aging in ambient air. These findings demonstrate that molecular bridging is an effective route to simultaneously improve the efficiency and stability of PSCs.","PeriodicalId":5,"journal":{"name":"ACS Applied Materials & Interfaces","volume":"18 41","pages":"56246–56255"},"PeriodicalIF":7.8,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149126069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mitochondria–Nanozyme Hybrid Therapeutic for Modulation of the Inflammatory Cascade in Psoriasis 线粒体-纳米酶混合治疗银屑病炎症级联的调节。

IF 7.8 2区材料科学

ACS Applied Materials & Interfaces Pub Date : 2026-10-21 Epub Date: 2026-10-09 DOI: 10.1021/acsami.6c15258

Siyu Chen, Yanan Wei, Wei Huang, Ruonan Zhang, Honghong Yu, Ya Wen, Xingyu Li, Jingyin Bao, Dong Li

{"title":"Mitochondria–Nanozyme Hybrid Therapeutic for Modulation of the Inflammatory Cascade in Psoriasis","authors":"Siyu Chen, Yanan Wei, Wei Huang, Ruonan Zhang, Honghong Yu, Ya Wen, Xingyu Li, Jingyin Bao, Dong Li","doi":"10.1021/acsami.6c15258","DOIUrl":"10.1021/acsami.6c15258","url":null,"abstract":"The chronic recurrence of psoriasis is driven by a self-amplifying inflammatory cascade in which oxidative stress and mitochondrial metabolic dysfunction reinforce each other, and single-target conventional therapies often fail to break this cycle. Here, we present a micro–nano hybrid system, Mito-Ce, constructed by covalently immobilizing ceria nanozymes (CeNPs) onto the surface of isolated functional mitochondria through thiol–maleimide chemistry. This design endows the hybrid with dual functionalities, including mitochondrial bioactivity and durable ROS-scavenging capabilities of CeNPs. In H2O2-stimulated macrophages, upon internalization. Mito-Ce markedly reduced intracellular ROS and consequently suppressed the secretion of pro-inflammatory cytokines (IL-6, TNF-α, and IL-1β). Topical application of Mito-Ce to an imiquimod-induced mouse model of psoriasis visibly resolved psoriatic plaques, reduced the PASI score, and reversed epidermal hyperplasia. Beyond local repair, Mito-Ce rebalanced systemic immunity, evidenced by a decline in splenic pathogenic Th17 cells and polarization toward anti-inflammatory M2 macrophages. Transcriptomic profiling further revealed that Mito-Ce broadly reversed the pathological gene expression program, downregulating stress-responsive and phagocytosis-related genes while upregulating genes associated with metabolism, epidermal proliferation, and tissue homeostatic remodeling. These coordinated networks ultimately re-established immune–barrier homeostasis at the molecular level. Collectively, by integrating nanozyme-mediated ROS scavenging with mitochondrial bioactivity, the Mito-Ce hybrid could treat psoriasis through coordinated disruption of the inflammatory cascade, potentially offering a highly effective platform for various chronic inflammatory disorders.","PeriodicalId":5,"journal":{"name":"ACS Applied Materials & Interfaces","volume":"18 41","pages":"55976–55987"},"PeriodicalIF":7.8,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149147395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Trace Bifunctional Diboron Additive Enables Robust CEI/SEI Interphases for Long-Cycling 4.5 V Li||NCM811 Batteries 微量双功能双硼添加剂可为长循环4.5 V Li||NCM811电池提供稳健的CEI/SEI界面

IF 7.8 2区材料科学

ACS Applied Materials & Interfaces Pub Date : 2026-10-21 Epub Date: 2026-10-10 DOI: 10.1021/acsami.6c15184

Yahui Zhang, Detian Ma, Yebo Song, Yueyang Gao, Yunfei Bai, Dawei Yu, Jincai Wu, Xiaobo Pan

{"title":"Trace Bifunctional Diboron Additive Enables Robust CEI/SEI Interphases for Long-Cycling 4.5 V Li||NCM811 Batteries","authors":"Yahui Zhang, Detian Ma, Yebo Song, Yueyang Gao, Yunfei Bai, Dawei Yu, Jincai Wu, Xiaobo Pan","doi":"10.1021/acsami.6c15184","DOIUrl":"10.1021/acsami.6c15184","url":null,"abstract":"Developing efficient, low-cost, multifunctional additives that require small amounts and can simultaneously protect both the cathode and anode remains a major challenge for the practical application of lithium batteries. Herein, bis(2,4-dimethylpentane-2,4-glycolato)diboron (B2hmp2) was introduced to construct a greatly Li+-conductive cathode electrolyte interphases (CEIs) at the LiNi0.8Co0.1Mn0.1O2 (NCM811) surface together with robust solid electrolyte interphases (SEIs). Using a common electrolyte with 0.2 wt % B2hmp2, the Li||Li cells deliver markedly enhanced long-cycling stability, sustaining stable operation for 500 h at 0.5 mA cm–2. Furthermore, following 350 cycles at 0.5 C, the capacity retention of 4.5 V Li||NCM811 cells was elevated from 57.2 to 83.6%. Experimental results reveal that the thin, uniform, boron-rich CEI generated by B2hmp2 effectively mitigates particle microcracking and restrains the dissolution of transition metal ions. Interface analysis reveals that the modified SEI film enriched with B–O species and LiF facilitates uniform Li plating/stripping without dendrite formation and reduces the continuous parasitic decomposition of electrolyte solvents. This article highlights the value of trace diboron for forming desirable electrolyte interphases to obtain the wonderful long-term cycle performance and rate performance of Li||NCM811 cells.","PeriodicalId":5,"journal":{"name":"ACS Applied Materials & Interfaces","volume":"18 41","pages":"56157–56168"},"PeriodicalIF":7.8,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149151216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ultrastable Cycling of Sodium Metal Battery at Rates Exceeding 20 C Achieved with a NaB3H8-SiO2 Composite Solid Electrolyte 使用NaB3H8-SiO2复合固体电解质实现钠金属电池在超过20℃下的超稳定循环

IF 7.8 2区材料科学

ACS Applied Materials & Interfaces Pub Date : 2026-10-21 Epub Date: 2026-10-12 DOI: 10.1021/acsami.6c10920

Anqi Zhu, Pengtao Qiu, Yang Luo, Ning Feng, Guang-Jing Feng, Shujun Li, Liqing He, Yiying Wu, Xuenian Chen

{"title":"Ultrastable Cycling of Sodium Metal Battery at Rates Exceeding 20 C Achieved with a NaB3H8-SiO2 Composite Solid Electrolyte","authors":"Anqi Zhu, Pengtao Qiu, Yang Luo, Ning Feng, Guang-Jing Feng, Shujun Li, Liqing He, Yiying Wu, Xuenian Chen","doi":"10.1021/acsami.6c10920","DOIUrl":"10.1021/acsami.6c10920","url":null,"abstract":"Solid-state sodium metal batteries are promising candidates for grid-scale energy storage due to their inherent safety and low cost. However, the development of solid electrolytes that support high-rate (>20 C) cycling for fast-charging applications remains a major challenge. Herein, we explore how adding SiO2 affects the ionic conductivity and dendrite suppression of NaB3H8, to develop superior solid electrolytes for high-rate batteries. The composites featuring an amorphous passivating layer with B–O bonds were fabricated via ball milling. Among them, NaB3H8-40%SiO2 exhibits the best conductivity, reaching 0.62 mS cm–1 at 25 °C, 2 orders of magnitude higher than that of pristine NaB3H8. Crucially, by reducing electronic conductivity and enhancing mechanical strength, it possesses a high critical current density of up to 6.5 mA cm–2, significantly higher than that of other reported hydridoborates. The Na/NaB3H8-40%SiO2/TiS2 batteries exhibit superior rate capability (216.4 mAh g–1 at 1 C and 143.1 mAh g–1 at 20 C) and long-term cycling stability (nearly 100.0% capacity retention after 2000 cycles at 20 C) at 30 °C. This work offers a promising approach for the development of innovative solid electrolytes in fast-charging or high-power-density sodium metal batteries.","PeriodicalId":5,"journal":{"name":"ACS Applied Materials & Interfaces","volume":"18 41","pages":"56048–56058"},"PeriodicalIF":7.8,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149151928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0