chemistry of plant raw material最新文献

{"title":"RIBES FRAGRANS PALLAS: SUPERCRITICAL CO2 EXTRACTION AND TANDEM MASS SPECTROMETRY","authors":"M. Razgonova, Andrey Shamilevich Sabitov, Yulia N Zinchenko, T. Senotrusova, Natalya Gavroshevna Li, Ekaterina Anatolyevna Vitomskova, K. Golokhvast","doi":"10.14258/jcprm.20240113178","DOIUrl":"https://doi.org/10.14258/jcprm.20240113178","url":null,"abstract":"Supercritical fluid technology was used to obtain bioactive substances from leaves of Ribes fragrans Pallas. The supercritical fluid technology proved to be the most effective type of extraction, giving the highest yield of metabolome composition of R. fragrans. Several experimental conditions were investigated in the pressure range 50–300 bar, with the used volume of co-solvent ethanol in the amount of 2.5% in the liquid phase at a temperature in the range of 31–70 °C. The most effective extraction conditions are: pressure 200 Bar and temperature 55 °C for leaves of R. fragrans. The CO2-extract of leaves of R. fragrans contain various polyphenolic compounds and compounds of other chemical groups with valuable biological activity. For the first time, the metabolome of supercritical extracts of R. fragrans leaves was studied in this research. Tandem mass-spectrometry (HPLC-ESI – ion trap) was applied to detect target analytes. The four-stage ion separation mode was implemented 79 different bioactive components have been identified in R. fragrans extracts. Twenty chemical compounds from polyphenol group and twelve chemical compounds from other chemical groups were identified for the first time in genus Ribes.","PeriodicalId":9946,"journal":{"name":"chemistry of plant raw material","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140447220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ECOLOGICAL AND HYGIENIC ASSESSMENT OF THE QUALITY OF BURDOCK ROOTS OF LARGE FLORA OF URBANIZED TERRITORIES OF THE CENTRAL BLACK EARTH REGION","authors":"N. Dyakova","doi":"10.14258/jcprm.20230311743","DOIUrl":"https://doi.org/10.14258/jcprm.20230311743","url":null,"abstract":"The roots of the bladder are mainly used in the form of aqueous extracts, and the pharmacological effect is due to water-soluble compounds based on polysaccharides. The study of the peculiarities of accumulation of this group of compounds is relevant. The aim of this study the relationship between the accumulation of heavy metals and arsenic and biologically active substances in the roots of ordinary burdock, collected on the territory of the Voronezh region in biogeocenoses experiencing various anthropogenic effects. In the Voronezh region, 51 points of harvesting plant raw materials were selected. The study of the content of heavy metals and arsenic in the roots of the bladder, the sum of polysaccharides in terms of fructose and the sum of extractive substances extracted by water was conducted according to pharmacopeic methods. The total amount of gravimetrically precipitated water-soluble polysaccharides was determined by a previously developed and validated patented procedure. Correlation coefficients were analyzed to examine in detail the effects of heavy metals and arsenic on the accumulation of biologically active substances. Of the samples examined, some do not meet the requirements of the regulatory documentation for arsenic content. Significant physiological barriers have been identified to the accumulation of ecotoxicants in the roots of common burdock, which is especially noticeable for elements such as lead, mercury, arsenic, cadmium, cobalt and chromium. The raw material can selectively concentrate copper and zinc. In eight samples prepared under urbocenosis conditions, this indicator was below the minimum numerical value. Low correlation of the content of large sum of gravimetrically determined polysaccharides and extractive substances in samples of burdock roots was revealed. extracted with water, containing heavy metals and arsenic, wherein the numerical value of the sum of the polysaccharides in terms of fructose is largely dependent on the concentration of toxic elements in the plant; which is probably due to the formation of strong metal-monosaccharide complexes, which make it difficult to obtain colored complexes of monomer sugars with a complexing agent during spectrophotometric determination.","PeriodicalId":9946,"journal":{"name":"chemistry of plant raw material","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140451904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"FEATURES OF MANIFESTATION OF ANTIOXIDANT PROPERTIES OF HYDROLYSIS LIGNIN IN POLYETHYLENE FILMS, ANTAGONISM OF LIGNIN AND LICHEN EXTRACTS","authors":"Elena Valerievna Vorobyova","doi":"10.14258/jcprm.20240112005","DOIUrl":"https://doi.org/10.14258/jcprm.20240112005","url":null,"abstract":"The work experimentally studied the antioxidant properties of hydrolyzed lignin powder in the composition of polyethylene films, showing the possibility of increasing the antioxidant capacity of lignin powder in the polymer matrix due to the adsorption of compounds with antioxidant properties on its surface. \u0000Samples of polyethylene films with a lignin content of 1–7% wt. obtained by thermal pressing. Thermal-oxidative testing of polymer films was carried out at a temperature of 150 °C. Monitoring of the oxidation process was carried out by IR spectroscopy, using the absorption band at 1720 cm-1, which corresponds to carbonyl groups. \u0000Experiments on adsorption of ascorbic acid and resorcinol (weak antioxidants) on the surface of lignin particles were carried out. An increase in the antioxidant properties of modified lignin in the composition of polyethylene films was noted. \u0000Lignin modification with Evernia prunastri lichen extracts; Parmelia sulcata; Hypogymnia physodes led to antagonism (negative synergism) of antioxidant properties in the polymer composition: the thermal-oxidative stability of the experimental polymer films turned out to be extremely low. At the same time, the extracts of the lichens Evernia prunastri, Parmelia sulcata, Hypogymnia physodes themselves exhibit high antioxidant activity in the composition of polyethylene films. The ATR spectra of lignin powders and UV/VIS spectra of lichen extracts were studied before and after mutual contacting. Analysis of the spectra indicates a decrease in the number of oxygen-containing groups of lignin, which determine its antioxidant capacity.","PeriodicalId":9946,"journal":{"name":"chemistry of plant raw material","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140450479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"COMPARATIVE CHARACTERISTICS OF THE LOW MOLECULAR WEIGHT METABOLOME OF MACROPHYTES IN DIFFERENT WATER BODIES IN THE WATER AREA OF THE KANDALAKSHA BAY OF THE WHITE SEA","authors":"E. Yavid, V. Khodonovich, Y. Krylova, Evgeniy Kurashov, Roman Evgenievich Smagin","doi":"10.14258/jcprm.20240113005","DOIUrl":"https://doi.org/10.14258/jcprm.20240113005","url":null,"abstract":"The Kandalaksha Bay of the White Sea underwent a first-of-its-kind comparative examination of the composition of essential oils of structure-forming macrophytes growing in freshwater and saltwater habitats. The essential oils of the aquatic macrophytes Nuphar lutea (L.) Sm., Ruppia maritima L., Zostera marina L., Fucus vesiculosus L., and Ascophyllum nodosum (L.) Le Jolis were obtained by steam hydrodistillation using the Clevenger apparatus from dried plants. Gas chromatography-mass spectrometry (GC/MS complex SHIMADZU GCMS-QP2010 Ultra) was used to analyze the qualitative and quantitative composition of LMWOCs (low molecular weight organic compounds). The component composition of the low molecular weight metabolome (LM) of macrophytes was shown to depend on both plant species specificity and plant habitat conditions (hydrological features, trophic state). More LMWOCs are found in plants from freshwater habitats than from marine ones. The investigated plants had only a few major compounds, ranging in number from 4 to 14. They accounted for between 70 and 83% of the overall concentration of all compounds in freshwater N. lutea and between 82 and 95% of the total concentration of LMWOCs in marine macrophytes. The most significant (% of the total essential oil) main components in macrophytes were carboxylic acids, specifically hexadecanoic, tetradecanoic, linoleic, and linolenic. The outcomes gained proved that the presence of carboxylic acids is a sign of a healthy macrophyte environment. The composition of LM of plants from northern habitats (marine and freshwater) contains high total concentrations of LMWOCs (including valuable ones from the perspective of economic use), making it possible to consider them as a valuable natural renewable resource for obtaining raw materials for various economic uses.","PeriodicalId":9946,"journal":{"name":"chemistry of plant raw material","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139960404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"BIOCHEMICAL AND MACROELEMENT COMPOSITION OF CHINESE LEYMUS (LEYMUS CHINENSIS (TRIN.) TZVEL.) IN THE UDA RIVER VALLEY (WESTERN TRANSBAIKALIA)","authors":"Lyudmila Nikolaevna Boloneva, M. Merkusheva, Natalya Karlovna Badmaeva, I. N. Lavrentieva","doi":"10.14258/jcprm.20240112864","DOIUrl":"https://doi.org/10.14258/jcprm.20240112864","url":null,"abstract":"Leymus chinensis in the valley of the middle reaches of the Uda River forms significant areas of forage lands, being a valuable resource species. Its production, the number of vegetative and generative shoots, their height, and spike length varied significantly. For the first time, the biochemical and mineral composition, nutritive and energy values of this species were determined for the northeast of the Western Transbaikalia and their compliance with the standards of plant fodder was established mainly except for the increased content of crude fiber. Protein ratio, as an indicator of feed digestibility, had medium (1 : 6/8–7.7) and wide (1 : 8.7–9.1) levels. The sum of digestible nutrients, total and metabolizable energy content of the forage were relatively constant, which is due to the short growing season in the sharply continental climate of the region. It was shown for the first time that the chemical composition of morphological components (leaves, stems, ears) of L. chinensis growing in floodplain steppe meadows changed little and had a set of elements-dominants: ears – N>K>P, leaves – N>K>Ca, stems – N>K>S(P). Because of the high concentration of sulfur in the ears of plants on saline soil, the elements were arranged as follows: N>S>K. It was found that the difference in the content of carbon and macroelements in the plants of the species growing in similar conditions of the steppe floodplain was insignificant and differed significantly in salinity. The peculiarity of the mineral composition of the above-ground phytomass was the high amount of S as well as a very wide K/Na ratio (38–65). The evaluation of the current state of productivity and quality of this species as a valuable resource cereal was given.","PeriodicalId":9946,"journal":{"name":"chemistry of plant raw material","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139960149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"COMPARATIVE CONTENT OF ASCORBIC ACID, TANNINS, TOTAL ASH IN ABOVEGROUND AND UNDERGROUND ORGANS OF REPRESENTATIVES OF THE GENUS HOSTA TRATT.","authors":"L. Sedelnikova, O. Tsandekova","doi":"10.14258/jcprm.20240112471","DOIUrl":"https://doi.org/10.14258/jcprm.20240112471","url":null,"abstract":"The content of phenolic compounds (tannins), ascorbic acid, ash substances in leaves, flowers, roots of Hosta decorata, H. sieboldiana, H. lancifolia, H. crispula, H. undulata and two varieties: Stiletto, Night before Cristmas cultivated in the forest-steppe zone of Western Siberia was analyzed. Stable indicators were found in ascorbic acid leaves in the range of 11.01–11.90 mg/100 g. The content of tannins (2.01–2.24%) in the leaves of H. undulata, H. ventricosa, cultivar Stiletto is 2 times higher than that of H. decorata, H. sieboldiana, H. lancifolia, H. crispula, cultivar Night before Cristmas. It was established for the first time that in the flowers of H. sieboldiana and the Night before Cristmas variety, the content of ash substances, ascorbic acid, tannins is 1.5–2 times higher than H. crispula, H. undulata, H. ventricosa, H. decorata and Stiletto varieties. It was found that in the underground organs of H. decorata the concentration of tannins, ascorbic acid and ash substances is 1.5–2 times higher. In general, the adaptive ability of introduced species and varieties is manifested in the individual content of secondary metabolites and ash substances in vegetative and generative organs during the period of mass flowering of plants.","PeriodicalId":9946,"journal":{"name":"chemistry of plant raw material","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139960459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"COMPARATIVE CHARACTERISTICS OF THE CONTENT OF A NUMBER OF BIOLOGICALLY ACTIVE SUBSTANCES IN KIWI FRUITS","authors":"Lesik Yankovic Aiba, Natalia Borisovna Platonova, O. Belous","doi":"10.14258/jcprm.20240112514","DOIUrl":"https://doi.org/10.14258/jcprm.20240112514","url":null,"abstract":"The content of biologically active substances in new promising varieties of kiwi breeding of the Research Institute of Agriculture of the Academy of Sciences of Abkhazia is considered. A spectrophotometric method for determining biologically active substances (anthocyanins, photosynthetic pigments, polyphenols) was used, which is based on determining the optical density of the solution of the analyzed substances at certain wavelengths. The aim is to analyze the varietal specification of kiwi fruits for the accumulation of biologically active substances such as pigments (anthocyanins, chlorophyll and carotenoids) and polyphenols in them. Five main groups of anthocyanins were quantified in fruits, and a significant excess of the amounts of this class of pigments was noted in the cv. Pobeditel (the amount of anthocyanins was 375.46 mg/100 g at 122.85–170.01 mg/100 g in the remaining varieties; LSD05 = 9.34). The predominant group of anthocyanin pigments in kiwi fruits is pelargonidin-3-glucoside, the content of which in varieties is in the range of 26.43 mg/100 g (cv. Slava) – 79.00 mg/100 g (cv. Pobeditel). The content of chlorophylls and carotenoids was determined, the greater amount of which accumulates in the fruits of the cv. Otkhara (1.58 mg/100 g of chlorophyll and 0.37 mg/100 g of carotenoids) and cv. Gulripshsky (1.58 and 0.23 mg/100 g, respectively). The amount of polyphenols synthesized in fruits has been established. The cv. Pobeditel and cv. Gulripshsky are the most rich in phenolic components (1576.5–1582.6 mg/100 g). The data of biochemical analyses showed the prospects of three new golden varieties without pubescence: Pobeditel, Gulripshsky and Otkhara. The results obtained will be used in further breeding work to obtain varieties that are the richest in biologically active substances of an antioxidant nature, and are of undoubted interest to the consumer.","PeriodicalId":9946,"journal":{"name":"chemistry of plant raw material","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139963000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PHYTOCHEMICAL COMPOSITION OF RAW MATERIALS OF BUPLEURUM LONGIFOLIUM SSP. AUREUM L. (FISCH. EX HOFFM.) SOO) ON THE BORDER OF THE RANGE OF THE TATARSTAN REPUBLIC","authors":"S. A. Dubrovnaya, Landysh Zavdetovna Khusnetdinova, A. Akulov, Lyudmila Valerianovna Ryzhova, Olga Arnoldovna Тimofeeva","doi":"10.14258/jcprm.20240112925","DOIUrl":"https://doi.org/10.14258/jcprm.20240112925","url":null,"abstract":"B. longifolium ssp. aureum cenopopulations were detected in forest phytocenoses of the coniferous-broad-leaved forests and the forest-steppe zones of the Republic of Tatarstan. In each habitat, the concentration of phenolic compounds, flavonoids, proanthocyanidins, and photosynthetic pigments was determined in 20 collected plants of the middle age ontogenetic state. Chromatographic analysis of phenolic compounds of the raw materials of each cenopopulation was carried out. \u0000It was found that the content of rutin and ferulic acid of plants in the zone of coniferous-broadleaf forests was higher than in the forest-steppe zone. However, there was a more diverse spectrum of phenolic compounds. The chlorogenic and benzoic acids, quercetin and kaempferol were detected. In all communities, high intra-population variation in the concentration of biologically active substances was revealed. This fact should be taken into account during plantation creations and raw materials collection.","PeriodicalId":9946,"journal":{"name":"chemistry of plant raw material","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139834977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"COMPLEXES OF WATER-SOLUBLE LOCAL PLANT POLYPHENOL DERIVATIVES AND THEIR BIOLOGICAL ACTIVITY","authors":"K. Rezhepov, Shiyrin Bekniyaz kizi Alimbayeva","doi":"10.14258/jcprm.20240112023","DOIUrl":"https://doi.org/10.14258/jcprm.20240112023","url":null,"abstract":"The article is devoted to obtaining water-soluble complexes of iminoazo derivatives of gossypol, studying their physicochemical properties and biological activity. Aromatic, heterocyclic amines and sulfanilamide preparations were used as amine components in obtaining iminoazo derivatives of gossypol and their water-soluble complexes. The maximum values of wavelengths and the corresponding optical densities were determined in the UV spectra of compounds in acetone solvent. In order to determine the structure of the compounds, the infrared spectrum was taken and analyzed: the shift of the fundamental vibrational frequencies up to 31 cm-1 showed that the water-poly-N-vinylpyrrolidone in the compound is connected to a lesser extent as a result of hydrogen bonding. Obtaining complexes of azoderivatives of gossypol imines with poly-N-vinylpyrrolidone is related to the multi-functionality of the reactive groups of the ligand compound; formed hydrogen bonds due to the oxygen of the cycloamide group. For the first time, six new water-soluble complexes iminoazo derivatives of gossypol with poly-N-vinylpyrrolidone were obtained. The results of determination of interferon-inducing activity of compounds were analyzed. The activity was compared with the effectiveness of azo-, iminoazo derivatives of gossypol. According to the obtained results, it was shown that the effectiveness of water-soluble complexes iminoazo derivatives of gossypol.","PeriodicalId":9946,"journal":{"name":"chemistry of plant raw material","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139962466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CHROMATOGRAPHIC AND SPECTRAL STUDY OF ARCTIUM LAPPA AND ARCTIUM TOMENTOSUM FRUCTUS CULTIVATED IN ALTAI","authors":"Natalia Eduardovna Kolomiets, Roman Sergeevich Boev, Ludmila Vladimirovna Zhalnina, Abdujalil Kaid Hasan Ali","doi":"10.14258/jcprm.20240112476","DOIUrl":"https://doi.org/10.14258/jcprm.20240112476","url":null,"abstract":"Burdock is an ingredient of official and traditional medicines in different countries, its roots are used for food, biologically active additives, functional nutrition products, fertilizers, etc. A great demand led to the situation when many countries including Russia began the plant’s cultivation. Despite that, the aboveground parts of the plant including its fructus still remain expendable. At the moment, burdock fructus are officially used only in China and Japan. In Russia they are not used and studies of their chemical composition and pharmacological properties are scarce. \u0000The research showed that fructus of Arctium lappa and A. tomentosum cultivated in Altai using by traditional way of growing, and new of agrotechnics of cultivation contain lignans, hydroxycinamic acid, fatty acids and their derivatives, polysaccharides and anthocyanin’s. The use of a new cultivation technology increased the content of lignans and other BAS by 10–25%. Hydroxycinamic acid is one of the dominant substances in fructus by content, therefore it is possible to standardize raw material according to this parameter. The presence of methyl cis-9, cis-15-octadecadienoate and 11-Eicosenoic acid methyl ester in fructushas been discovered for the first time. Ethyl linoleate and methylfolate or methyl cis-9-octadecenoate are found to be dominant components of fatty acids and their derivatives. \u0000Additional studies of chemical composition, pharmacological properties, clinical approbation are needed to obtain evidence of the efficiency of burdock fructus utilization for clinical purposes and prevention.","PeriodicalId":9946,"journal":{"name":"chemistry of plant raw material","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139836147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}