Chest最新文献

{"title":"Long-term major respiratory mortality among 5-year survivors of adolescent and young adult cancer.","authors":"Po Hu,Wenping Zhu,Yunwei Chen,Wenxing Mei,Lai Wang","doi":"10.1016/j.chest.2025.10.007","DOIUrl":"https://doi.org/10.1016/j.chest.2025.10.007","url":null,"abstract":"BACKGROUNDAdolescent and young adult (AYA) diagnosed with cancer are at risk of experiencing pulmonary dysfunction even years or decades after completing treatment.RESEARCH QUESTIONIs the risk of major respiratory mortality (MRM) higher in long-term survivors of AYA cancers compared to the general population?STUDY DESIGN AND METHODSStudy analyzed data from the Surveillance, Epidemiology, and End Results (SEER) 8 database, covering 1975-2021. Standardized mortality ratios (SMRs) and absolute excess risks (AERs) were calculated, stratified by demographic and clinical characteristics.RESULTSA total of 125,051 5-year AYA cancer survivors (aged 15-39 years at diagnosis) were included. Overall, 443 MRM occurred, which was 1.1-fold [95% confidence interval (CI) 1.01-1.21] that expected in the general population, corresponding to 0.25 (95% CI 0.01-0.50) excess respiratory deaths per 10,000 person-years. Hodgkin's lymphoma was associated with the highest SMR for pneumonia deaths, while lung cancer had the highest SMR for chronic lower respiratory disease deaths. The AER for pneumonia deaths was more than twice as high in men as in women (0.7 versus 0.3). Additionally, Black survivors faced a 54% increased risk of death from chronic lower respiratory disease.INTERPRETATIONOur investigation highlights the heterogeneity in the risk of mortality due to respiratory diseases among long-term AYA cancer survivors in the United States. This risk varies across different cancer types, age demographics, and ethnicities. These findings provide useful insights for the development of personalized guideline aimed at long-term monitoring of pulmonary dysfunction in this expanding population.","PeriodicalId":9782,"journal":{"name":"Chest","volume":"42 1","pages":""},"PeriodicalIF":9.6,"publicationDate":"2025-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145288217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Targeting TH2 Cytokines and Alarmins in COPD Therapy: A Comprehensive Clinical Trial Landscape Analysis Based on the Trialtrove Database.","authors":"Tingting Xu,Xiangting Ge","doi":"10.1016/j.chest.2025.10.006","DOIUrl":"https://doi.org/10.1016/j.chest.2025.10.006","url":null,"abstract":"","PeriodicalId":9782,"journal":{"name":"Chest","volume":"102 1","pages":""},"PeriodicalIF":9.6,"publicationDate":"2025-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145283523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative outcomes and side effects of immunosuppressants and tumor necrosis factor inhibitors in sarcoidosis: a real-world data analysis.","authors":"Chao Wen-Cheng,Liao Shu-Yi","doi":"10.1016/j.chest.2025.09.130","DOIUrl":"https://doi.org/10.1016/j.chest.2025.09.130","url":null,"abstract":"BACKGROUNDSarcoidosis is a complex systemic granulomatous disease with varying clinical manifestations, and immunosuppressive agents and tumor necrosis factor (TNF) inhibitors have been used in severe and refractory cases. However, the comparison of the serious side effects of these treatments remains poorly understood.RESEARCH QUESTIONIn sarcoidosis, what is the one-year risk of serious side effects among second-line agents (immunosuppressants) and TNF inhibitors?STUDY DESIGN AND METHODSA retrospective analysis of data from the TriNetX Research Network, which includes de-identified medical records of sarcoidosis patients treated with specific immunosuppressive agents or TNF inhibitors between 2012 and 2023 across 82 healthcare organizations. Propensity score matching (PSM) was employed to mitigate confounding effects.RESULTSA total of 13,814 patients receiving immunosuppressive agents were included. We found that patients who received mycophenolate mofetil had higher risks for inpatient hospitalization (HR 2.74, 95% CI: 2.11-3.56), critical care (HR 2.37, 95% CI 1.91-2.94), mechanical ventilation (HR 4.04, 95% CI 2.63-6.21), mortality (HR 2.16, 95% CI 1.70-2.75), and infections compared with those underwent methotrexate. Azathioprine use has increased risks of mortality, hematologic toxicity, and infections compared to methotrexate. Among the 3,964 patients with sarcoidosis receiving TNF inhibitors, we found similar rare of serious side effects between infliximab and adalimumab, although a slightly higher risk of anemia (HR 1.81, 95% CI 1.22-2.67), thrombocytopenia (HR 2.67, 95% CI 1.75-4.07) and pneumonia (HR 1.47, 95% CI 1.02-2.10), but lower risk of skin soft tissue infection (HR 0.39, 95% CI 0.17-0.89) in infliximab group.INTERPRETATIONWe used large real-world data with the PSM approach to demonstrate the heightened risk of infection and bone marrow suppression with mycophenolate mofetil compared with the other immunosuppressants, and a similar rate of serious side effects between infliximab and adalimumab.","PeriodicalId":9782,"journal":{"name":"Chest","volume":"102 1","pages":""},"PeriodicalIF":9.6,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145277327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Validation of a Multidimensional Diagnostic Approach for Chronic Obstructive Pulmonary Disease in Chinese.","authors":"Fan Wu,Suyin Huang,Kunning Zhou,Tingting Xia,Qi Wan,Gaoying Tang,Zhishan Deng,Youlan Zheng,Ningning Zhao,Heshen Tian,Cuiqiong Dai,Lifei Lu,Xiaohui Wu,Zihui Wang,Xiaoyan Huang,Xiaohuan Pan,Jian Zhang,Xianliang Zeng,Zhifeng Gao,Changli Yang,Shengtang Chen,Yongqing Huang,Shuqing Yu,Erkang Yi,Yu Deng,Surya P Bhatt,Yumin Zhou,Pixin Ran, ","doi":"10.1016/j.chest.2025.10.002","DOIUrl":"https://doi.org/10.1016/j.chest.2025.10.002","url":null,"abstract":"BACKGROUNDAlthough spirometry is used to diagnose COPD, a new multidimensional diagnostic schema has been recently proposed to diagnose this disease. However, evidence in Chinese individuals and never smokers is limited.RESEARCH QUESTIONIs the new multidimensional diagnostic method for COPD practical in the Chinese population and never smokers?STUDY DESIGN AND METHODSWe analyzed data from a 3-year, prospective, multicenter, community-based cohort study. The previous diagnostic criterion for COPD was postbronchodilator FEV1/FVC<0.70. The new multidimensional diagnostic schema includes the major diagnostic category (presence of the major criterion and at least 1 of 5 minor criteria) and minor diagnostic category (presence of least 3 of 5 minor criteria). The main criterion is postbronchodilator FEV1/FVC<0.70. The minor criteria include emphysema, bronchial wall thickening, dyspnea, poor quality of life, and chronic bronchitis. We conducted subgroup analysis among never smokers.RESULTSAmong participants without airflow obstruction, 4.8% (55/1140) met the multidimensional diagnostic criteria; 5.8% (53/915) of participants with airflow obstruction did not meet these criteria. Participants with airflow obstruction who were excluded using the multidimensional diagnostic schema for COPD had a risk of exacerbations and annual decline in lung function similar to that in participants diagnosed as normal using both criteria. Participants without airflow obstruction reclassified as having COPD had a higher risk of exacerbations compared with those diagnosed as normal using both criteria. Similar results were found in never smokers.INTERPRETATIONThe new multidimensional diagnostic schema for COPD can exclude individuals with airflow obstruction who have a favorable respiratory prognosis and identify those without airflow obstruction who are at higher risk for exacerbations in Chinese and never smokers.","PeriodicalId":9782,"journal":{"name":"Chest","volume":"13 1","pages":""},"PeriodicalIF":9.6,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145277330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research Letter: The Association Between Incident Nontuberculous Mycobacteria Isolation and Antibiotic Exposure in Patients with Bronchiectasis.","authors":"Meghan Marmor,Amanda E Brunton,David Fraulino,Stephen J Ruoss,Emily Henkle,B Shoshana Zha,Mark Metersky,Kevin Winthrop, ","doi":"10.1016/j.chest.2025.09.122","DOIUrl":"https://doi.org/10.1016/j.chest.2025.09.122","url":null,"abstract":"","PeriodicalId":9782,"journal":{"name":"Chest","volume":"86 1","pages":""},"PeriodicalIF":9.6,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145261619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pleural Manometry in Pneumothorax: Evaluating Tension Physiology and Predicting Outcomes.","authors":"Ardian Latifi,Dylan Wang,Elliot D Backer,Nagendra Madisi,Amit Chopra,Christopher M Kapp,Max Wayne,John Howe,Cheryl Pai,Lonny Yarmus,David Feller-Kopman,Jeffrey Thiboutot","doi":"10.1016/j.chest.2025.09.121","DOIUrl":"https://doi.org/10.1016/j.chest.2025.09.121","url":null,"abstract":"BACKGROUNDTension pneumothorax is traditionally defined as when pleural pressure (PPl) exceeds atmospheric pressure, which reduces venous return and leads to hemodynamic collapse. However, PPl has yet to have been directly measured in tension pneumothorax due to technical limitations, nor has it been studied in predicting outcomes for pneumothorax.RESEARCH QUESTIONDo increased pleural pressures increase the risk of tension pneumothorax, and are they associated with pleurodesis or death?STUDY DESIGNand methods: In this multi-center, prospective observational study, participants with newly diagnosed pneumothorax (tension and nontension) were recruited. PPl throughout the respiratory cycle was measured at the time of chest thoracostomy and patients were followed for outcomes of pleurodesis and death during hospitalization.RESULTSAt five centers, 37 patients presenting with a pneumothorax (9 tension, 28 non-tension) were enrolled. 73% of recruited patients had an iatrogenic pneumothorax. Both increased inspiratory (OR 1.40, 95% CI 1.10-1.76) and expiratory PPl (OR 1.22, 95% CI 1.05-1.42) were associated with increased risk of tension. A subset of patients without tension were found to have supraatmospheric PPl. Lower inspiratory PPl was also associated with an increased risk for pleurodesis (OR 0.66, 95% CI 0.45, 0.96).INTERPRETATIONMeasurement of PPl in tension pneumothorax is feasible. Elevated PPl alone may not dictate the development of tension pneumothorax. In this small study, with a majority of iatrogenic pneumothorax, there is an association between PPl and need for pleurodesis which may be a useful predictive tool to guide earlier definitive management. These findings should be further explored in other causes of pneumothorax as well.","PeriodicalId":9782,"journal":{"name":"Chest","volume":"86 1","pages":""},"PeriodicalIF":9.6,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145261612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gastroesophageal Balloon Tamponade Simulation-based Mastery Learning Curriculum for Critical Care Fellows.","authors":"Christopher J Mowry,Michael Kriss,Maria Moreira,Anna Neumeier","doi":"10.1016/j.chest.2025.09.120","DOIUrl":"https://doi.org/10.1016/j.chest.2025.09.120","url":null,"abstract":"BACKGROUNDGastroesophageal balloon tamponade (GEBT) tube placement is a life-saving measure used as a bridge to definitive therapy in patients with variceal hemorrhage refractory to medical and endoscopic therapy. As a high-acuity, low-occurrence (HALO) procedure, proficiency may not be achieved through clinical experience alone.RESEARCH QUESTIONCan a simulation-based mastery learning (SBML) curriculum improve competence with GEBT among pulmonary and critical care medicine (PCCM) fellows?STUDY DESIGN AND METHODSNeeds assessments were completed locally by University of Colorado PCCM fellows and nationally by PCCM and critical care medicine (CCM) program directors to guide curriculum development, which resulted in a procedural training video, large group didactic, and small group deliberate practice skills session using 3-D printed gastroesophageal models. A simulation assessment checklist was developed using a Delphi process and a minimum passing standard (MPS) was derived using the modified Angoff method. PCCM fellows participated in the curriculum and a pretest-posttest design was utilized to evaluate the curricular impact on participant confidence, knowledge, and procedural skill. A subgroup of participants was reassessed at varying time intervals to explore skill deterioration with time.RESULTSA 23-item simulation assessment checklist with an MPS of 16/23 items correct was developed. 26 PCCM fellows participated in the curriculum with significant improvement in confidence comparing pre- versus post-testing (median 4 vs 1; P < 0.01; 5-point Likert scale, 1 [not at all confident] to 5 [completely confident]). Fellows demonstrated significant improvement in knowledge (82% vs 44% items correct; P < 0.01) on a 16-item questionnaire and on simulation assessment (20.4 vs 8.6 correct steps; P < 0.01). All participants achieved the MPS on post-testing. Follow-up assessments demonstrated skill deterioration as more than 50% of participants no longer achieved the MPS at 6 months.INTERPRETATIONThis SBML curriculum improved learner confidence, knowledge, and procedural competence with GEBT and provides a curricular model for other HALO procedures. Skill deterioration was demonstrated after completing the curriculum and methods to slow deterioration and reinforce proficiency warrant further investigation.","PeriodicalId":9782,"journal":{"name":"Chest","volume":"24 1","pages":""},"PeriodicalIF":9.6,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145261615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inspiratory effort and dynamic transpulmonary driving pressure in extremely preterm infants.","authors":"Daniele De Luca,Sofia De La Rubia,Francesca Miselli,Guillaume Emeriaud,Barbara Loi,Marco Piastra,Giorgio Conti,Massimo Antonelli,Domenico Luca Grieco","doi":"10.1016/j.chest.2025.09.119","DOIUrl":"https://doi.org/10.1016/j.chest.2025.09.119","url":null,"abstract":"BACKGROUNDIn preterm infants receiving noninvasive ventilation, data about inspiratory effort (ΔPes) and transpulmonary driving pressure (ΔPL) are scarce. Electrical activity of the diaphragm (EAdi) can estimate ΔPes and ΔPL when patient size precludes more accurate measurements. This estimation may reveal new insights into respiratory pathophysiology and potential risk of self-inflicted lung injury in neonates on noninvasive support.RESEARCH QUESTIONWhat are the characteristics of ΔPes and ΔPL in extremely preterm infants undergoing noninvasive ventilation?STUDY DESIGN AND METHODSProspective, observational pilot cohort study, in which EAdi was recorded in neonates receiving noninvasive ventilation during recovery from respiratory distress syndrome (RDS), in those with evolving bronchopulmonary dysplasia (BPD), and in term controls. EAdi was used to estimate ΔPes and ΔPL. In a subset of RDS and BPD patients, diaphragmatic thickening fraction (TF) and SpO2/FiO2 were recorded.RESULTSTen patients with RDS, 25 patients with evolving BPD and 5 control term neonates were studied. Average EAdi, ΔPes, ΔPL, and TF were similar between controls, RDS and BPD patients. Inter-patient variability of ΔPes (RDS: 24 (9)%, BPD: 28 (9)%, controls: 10 (6)%, p<0.001) and ΔPL (RDS: 25 (7)%, BPD: 27 (9)%, controls: 17 (7)%, p=0.05) was higher in patients than in controls. Breaths with ΔPes>10 cmH2O occurred more often in BPD than in RDS patients (p=0.035) and controls (p=0.006). Breaths with ΔPL>20 cmH2O occurred similarly in patients with BPD or RDS and more frequently than in controls (p<0.001). EAdi-based estimations correlated with TF, and ΔPL had an inverse correlation with SpO2/FiO2 (ρ= -0.64,p=0.018).INTERPRETATIONΔPes and ΔPL show relevant variability in preterm infants. High ΔPes is more common in BPD patients than in those with RDS or controls. High ΔPL was observed in patients with BPD and RDS, occurred more often than in controls, and correlated with the degree of oxygenation impairment.","PeriodicalId":9782,"journal":{"name":"Chest","volume":"86 1","pages":""},"PeriodicalIF":9.6,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145261616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Positive Airway Pressure Therapy on Healthcare Resource Use in Patients with Obstructive Sleep Apnea and Coronary Artery Disease.","authors":"Peter A Cistulli,Anita S Malik,Adam V Benjafield,Naomi Alpert,Caleb Woodford,Jean-Louis Pepin,Kimberly L Sterling,Kate V Cole,Atul Malhotra,Ann Cameron,Gemma Figtree, ","doi":"10.1016/j.chest.2025.09.117","DOIUrl":"https://doi.org/10.1016/j.chest.2025.09.117","url":null,"abstract":"BACKGROUNDObstructive sleep apnea (OSA) is associated with coronary artery disease (CAD) risk. This study examined the impact of positive airway pressure (PAP) therapy adherence on healthcare resource use (HCRU) in patients with CAD and newly diagnosed OSA.RESEARCH QUESTIONIs adherence to PAP therapy associated with reduced HCRU in patients with CAD and OSA?STUDY DESIGN AND METHODSThis retrospective analysis linked administrative claims to objective PAP use data (ResMed AirView™) for adults (≥18 years) with CAD, newly diagnosed with OSA. 2-year adherence was defined by the number of 90-day timeframes in which adherence criteria were met. Inverse probability of treatment weighting was applied to assess primary outcomes of emergency room (ER) visits and hospitalizations 1- and 2-years post index.RESULTS32,911 patients were included (34.9% female, mean age 60.9 years). Compared to adherent patients, non-adherent patients were slightly younger, more commonly female, and had higher prevalence of severe obesity and comorbidities. Compared to non-adherent patients, adherent patients had significantly fewer ER visits (-26% and -24%, p<0.001) and all-cause hospitalizations (-35% and -39%, p<0.001) in years 1 and 2, respectively. HCRU for intermediately adherent patients fell between that of adherent and non-adherent patients. After risk adjustment, the threshold for minimum nightly PAP usage to derive a significant HCRU benefit was less than 3 hours per night (h/night) for all outcomes and time periods. There was a 4.7-5.9% reduction in HCRU rates with each additional h/night of PAP usage.INTERPRETATIONIn real-world patients with CAD and newly diagnosed OSA, PAP therapy adherence was associated with lower HCRU. These findings strongly support the importance of diagnosing and treating OSA these patients.","PeriodicalId":9782,"journal":{"name":"Chest","volume":"154 1","pages":""},"PeriodicalIF":9.6,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145261614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Post Intensive Care Syndrome Awareness and Communication: Surveys of ICU Providers and Patients.","authors":"Mark L Rolfsen,Matthew F Mart,Hannah Kieffer,David Krasinski,Timothy D Girard,Lauren E Ferrante,Robert L Owens,Ana Lucia Fuentes,Nathan Brummel,Carla M Sevin,John P Kress,Jaspal Singh,Sukhvinder Nagi,Kevin Shaw,Edward Qian,James C Jackson,Christopher G Hughes,Pratik Pandharipande,Mayur Patel,Tom Elasy,E Wesley Ely","doi":"10.1016/j.chest.2025.08.048","DOIUrl":"https://doi.org/10.1016/j.chest.2025.08.048","url":null,"abstract":"BACKGROUNDSurvivors of critical illness often experience new or worsening impairments in various domains of health following discharge, collectively referred to as the Post Intensive Care Syndrome (PICS). While this condition is common, it remains unclear whether providers are routinely communicating about survivorship and PICS to patients and families, and whether patients are remembering these conversations.RESEARCH QUESTIONHow often do Intensive Care Unit (ICU) providers discuss the concept of PICS with at-risk patients or families, and how often do patients remember being told about the concept of PICS?STUDY DESIGN AND METHODSWe distributed online surveys to ICU healthcare providers at nine U.S. institutions and to patients who survived critical illness in the preceding year at a single site.RESULTSWe collected a convenience sample of 382 provider responses and 148 patient responses. The providers were registered nurses (53.7%), physician fellows or attendings (33%), and advanced practice providers (13.4%). Patients had predominantly been admitted to surgical (41.1%), cardiovascular (41.1%), and medical (14.4%) ICUs. We found that 73.8% of providers reported having previously heard the term \"Post Intensive Care Syndrome.\" In comparison, only 16.6% of patients remembered ever being told the term. When asked how often they would discuss with patients or families the possibility of any new or worsening impairments following critical illness, less than a third (29.9%) of providers said they do so at least half the time. Only about a third (35.6%) of patients remembered such conversations.INTERPRETATIONAwareness of PICS is inconsistent among providers and low among patients. Few ICU team members report routinely talking to patients or families about the common, disabling impairments that often occur following critical illness. Few patients remember being told about the possibility of PICS. Further investigation is needed to determine how best to improve this communication gap.","PeriodicalId":9782,"journal":{"name":"Chest","volume":"105 2 1","pages":""},"PeriodicalIF":9.6,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145261611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}