Sandrine Hanna,Kristi Beermann,Deborah J Levine,Gabriel Loor,Jonathan P Singer,Patrick J Smith,Hakim Azfar Ali
{"title":"老年受体术后肺移植的考虑。","authors":"Sandrine Hanna,Kristi Beermann,Deborah J Levine,Gabriel Loor,Jonathan P Singer,Patrick J Smith,Hakim Azfar Ali","doi":"10.1016/j.chest.2024.10.060","DOIUrl":null,"url":null,"abstract":"TOPIC IMPORTANCE\r\nLung transplantation (LTx) remains the ultimate treatment for many patients with advanced lung disease. While the age cutoffs for LTx have been debated due to variable outcomes, the number of LTx procedures performed on patients aged 65 and older has significantly increased in recent decades, reflecting the realities of an aging demographic. This trend underscores the unique management challenges faced by this cohort and highlights the importance of addressing evidence gaps in their perioperative and postoperative care.\r\n\r\nREVIEW FINDINGS\r\nOur literature review highlights that, despite the challenges, recent data indicate favorable outcomes for patients aged 65 and older undergoing LTx. Although the primary focus of this article is on post-operative care, it also addresses some peri-operative considerations including the use of extra-corporeal life support, as well as the choice of the procedure type and donor considerations. This review incorporates current knowledge about early and late postoperative complications, including neurological, cardiovascular, renal, among others, along with their management strategies and current practice patterns. .\r\n\r\nSUMMARY\r\nIn conclusion, this review emphasizes the need to optimize care for older LTx recipients. The evidence regarding ideal management practices for this population is limited. We highlight the necessity for comprehensive postoperative management guidelines and identify key areas for further research to establish evidence-based protocols for this growing demographic.","PeriodicalId":9782,"journal":{"name":"Chest","volume":"3 1","pages":""},"PeriodicalIF":9.5000,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Post-Operative Lung Transplant Considerations in the Older Recipient.\",\"authors\":\"Sandrine Hanna,Kristi Beermann,Deborah J Levine,Gabriel Loor,Jonathan P Singer,Patrick J Smith,Hakim Azfar Ali\",\"doi\":\"10.1016/j.chest.2024.10.060\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"TOPIC IMPORTANCE\\r\\nLung transplantation (LTx) remains the ultimate treatment for many patients with advanced lung disease. While the age cutoffs for LTx have been debated due to variable outcomes, the number of LTx procedures performed on patients aged 65 and older has significantly increased in recent decades, reflecting the realities of an aging demographic. This trend underscores the unique management challenges faced by this cohort and highlights the importance of addressing evidence gaps in their perioperative and postoperative care.\\r\\n\\r\\nREVIEW FINDINGS\\r\\nOur literature review highlights that, despite the challenges, recent data indicate favorable outcomes for patients aged 65 and older undergoing LTx. Although the primary focus of this article is on post-operative care, it also addresses some peri-operative considerations including the use of extra-corporeal life support, as well as the choice of the procedure type and donor considerations. This review incorporates current knowledge about early and late postoperative complications, including neurological, cardiovascular, renal, among others, along with their management strategies and current practice patterns. .\\r\\n\\r\\nSUMMARY\\r\\nIn conclusion, this review emphasizes the need to optimize care for older LTx recipients. The evidence regarding ideal management practices for this population is limited. We highlight the necessity for comprehensive postoperative management guidelines and identify key areas for further research to establish evidence-based protocols for this growing demographic.\",\"PeriodicalId\":9782,\"journal\":{\"name\":\"Chest\",\"volume\":\"3 1\",\"pages\":\"\"},\"PeriodicalIF\":9.5000,\"publicationDate\":\"2025-04-22\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Chest\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1016/j.chest.2024.10.060\",\"RegionNum\":1,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CRITICAL CARE MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chest","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.chest.2024.10.060","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CRITICAL CARE MEDICINE","Score":null,"Total":0}
Post-Operative Lung Transplant Considerations in the Older Recipient.
TOPIC IMPORTANCE
Lung transplantation (LTx) remains the ultimate treatment for many patients with advanced lung disease. While the age cutoffs for LTx have been debated due to variable outcomes, the number of LTx procedures performed on patients aged 65 and older has significantly increased in recent decades, reflecting the realities of an aging demographic. This trend underscores the unique management challenges faced by this cohort and highlights the importance of addressing evidence gaps in their perioperative and postoperative care.
REVIEW FINDINGS
Our literature review highlights that, despite the challenges, recent data indicate favorable outcomes for patients aged 65 and older undergoing LTx. Although the primary focus of this article is on post-operative care, it also addresses some peri-operative considerations including the use of extra-corporeal life support, as well as the choice of the procedure type and donor considerations. This review incorporates current knowledge about early and late postoperative complications, including neurological, cardiovascular, renal, among others, along with their management strategies and current practice patterns. .
SUMMARY
In conclusion, this review emphasizes the need to optimize care for older LTx recipients. The evidence regarding ideal management practices for this population is limited. We highlight the necessity for comprehensive postoperative management guidelines and identify key areas for further research to establish evidence-based protocols for this growing demographic.
期刊介绍:
At CHEST, our mission is to revolutionize patient care through the collaboration of multidisciplinary clinicians in the fields of pulmonary, critical care, and sleep medicine. We achieve this by publishing cutting-edge clinical research that addresses current challenges and brings forth future advancements. To enhance understanding in a rapidly evolving field, CHEST also features review articles, commentaries, and facilitates discussions on emerging controversies. We place great emphasis on scientific rigor, employing a rigorous peer review process, and ensuring all accepted content is published online within two weeks.