老年受体术后肺移植的考虑。

IF 9.5 1区 医学 Q1 CRITICAL CARE MEDICINE
Chest Pub Date : 2025-04-22 DOI:10.1016/j.chest.2024.10.060
Sandrine Hanna,Kristi Beermann,Deborah J Levine,Gabriel Loor,Jonathan P Singer,Patrick J Smith,Hakim Azfar Ali
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引用次数: 0

摘要

肺移植(LTx)仍然是许多晚期肺部疾病患者的最终治疗方法。尽管由于预后不一,LTx的年龄下限一直存在争议,但近几十年来,65岁及以上患者进行LTx手术的数量显著增加,这反映了人口老龄化的现实。这一趋势强调了这一队列面临的独特管理挑战,并强调了在围手术期和术后护理中解决证据差距的重要性。我们的文献综述强调,尽管存在挑战,但最近的数据表明,65岁及以上的患者接受LTx治疗的结果是有利的。虽然这篇文章的主要重点是术后护理,但它也讨论了一些围手术期的注意事项,包括体外生命支持的使用,以及手术类型的选择和供体的考虑。本综述结合了目前关于早期和晚期术后并发症的知识,包括神经系统、心血管、肾脏等,以及它们的管理策略和当前的实践模式。总结:本综述强调了优化老年LTx受术者护理的必要性。关于这一人群的理想管理实践的证据有限。我们强调制定全面的术后管理指南的必要性,并确定进一步研究的关键领域,为这一不断增长的人口建立循证方案。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Post-Operative Lung Transplant Considerations in the Older Recipient.
TOPIC IMPORTANCE Lung transplantation (LTx) remains the ultimate treatment for many patients with advanced lung disease. While the age cutoffs for LTx have been debated due to variable outcomes, the number of LTx procedures performed on patients aged 65 and older has significantly increased in recent decades, reflecting the realities of an aging demographic. This trend underscores the unique management challenges faced by this cohort and highlights the importance of addressing evidence gaps in their perioperative and postoperative care. REVIEW FINDINGS Our literature review highlights that, despite the challenges, recent data indicate favorable outcomes for patients aged 65 and older undergoing LTx. Although the primary focus of this article is on post-operative care, it also addresses some peri-operative considerations including the use of extra-corporeal life support, as well as the choice of the procedure type and donor considerations. This review incorporates current knowledge about early and late postoperative complications, including neurological, cardiovascular, renal, among others, along with their management strategies and current practice patterns. . SUMMARY In conclusion, this review emphasizes the need to optimize care for older LTx recipients. The evidence regarding ideal management practices for this population is limited. We highlight the necessity for comprehensive postoperative management guidelines and identify key areas for further research to establish evidence-based protocols for this growing demographic.
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来源期刊
Chest
Chest 医学-呼吸系统
CiteScore
13.70
自引率
3.10%
发文量
3369
审稿时长
15 days
期刊介绍: At CHEST, our mission is to revolutionize patient care through the collaboration of multidisciplinary clinicians in the fields of pulmonary, critical care, and sleep medicine. We achieve this by publishing cutting-edge clinical research that addresses current challenges and brings forth future advancements. To enhance understanding in a rapidly evolving field, CHEST also features review articles, commentaries, and facilitates discussions on emerging controversies. We place great emphasis on scientific rigor, employing a rigorous peer review process, and ensuring all accepted content is published online within two weeks.
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