Ceylon Medical Journal最新文献_第9页

GAMBARAN EPIDEMIOLOGI DAN STIGMA SOSIAL TERKAIT PANDEMI COVID-19 DI KOTA TANGERANG SELATAN TAHUN 2020 2020年新冠肺炎世界北部城镇就业和社会服务

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Ceylon Medical Journal Pub Date : 2021-02-07 DOI: 10.36341/CMJ.V3I3.1506

Astri Kurnia Sari, Thresya Febrianti

{"title":"GAMBARAN EPIDEMIOLOGI DAN STIGMA SOSIAL TERKAIT PANDEMI COVID-19 DI KOTA TANGERANG SELATAN TAHUN 2020","authors":"Astri Kurnia Sari, Thresya Febrianti","doi":"10.36341/CMJ.V3I3.1506","DOIUrl":"https://doi.org/10.36341/CMJ.V3I3.1506","url":null,"abstract":"In December 2019, a case of peneumonia of unknown etiology was found in Wuhan, Hubei, China with clinical symptoms that closely resemble pneumonia, which is named COVID-19. The COVID-19 pandemic can cause feelings of fear of infection, anxiety, stigma, prejudice and marginalization of disease in patients, people at risk and healthy people to health workers. This study aims to describe the epidemiology and social stigma associated with the COVID-19 pandemic in South Tangerang City in 2020. This research is a type of quantitative research with a descriptive method with a cross sectional approach. The study was conducted in July 2020. The population in this study were the people of South Tangerang City. The sample used was 107 respondents with purposive sampling technique. Retrieval of data using a questionnaire via google form. Based on the results of the study, 73.8% of the respondents were 17-25 years old, 70.1% of the respondents were female. , the occupational status of the respondents is mostly students as much as 60.7% and the sub-districts where the respondents are mostly residing in Pamulang is 29.0%. People who do not have a stigma on COVID-19 patients are 56.1%. It is hoped that the public will remain vigilant and carry out health protocols during the COVID-19 pandemic and avoid stigmatizing COVID-19 patients in order to avoid someone hiding their health status.","PeriodicalId":9777,"journal":{"name":"Ceylon Medical Journal","volume":"3 1","pages":"104-109"},"PeriodicalIF":0.4,"publicationDate":"2021-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47344886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Brugada phenocopy unmasked during a febrile illness. 在发热性疾病期间发现的布鲁加达表型。

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Ceylon Medical Journal Pub Date : 2020-12-31 DOI: 10.4038/cmj.v65i4.9284

Devasmitha Wijesundara, Keshinie Samarasekara, Thashi Chang

引用次数: 0

Clinicopathological patterns and outcomes of urothelial bladder malignancies in Sri Lankan patients. 斯里兰卡患者尿路上皮膀胱恶性肿瘤的临床病理模式和结果。

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Ceylon Medical Journal Pub Date : 2020-12-31 DOI: 10.4038/cmj.v65i4.9281

Umesh Jayarajah, Hilary Fernando, Kasun Herath, Sanka Kuruppu, Uditha Wickramanayaka, Indika Fernando, Chandu De Silva, Serozsha Goonewardena

{"title":"Clinicopathological patterns and outcomes of urothelial bladder malignancies in Sri Lankan patients.","authors":"Umesh Jayarajah, Hilary Fernando, Kasun Herath, Sanka Kuruppu, Uditha Wickramanayaka, Indika Fernando, Chandu De Silva, Serozsha Goonewardena","doi":"10.4038/cmj.v65i4.9281","DOIUrl":"https://doi.org/10.4038/cmj.v65i4.9281","url":null,"abstract":"Introduction: Studies on bladder cancer in Sri Lanka have shown varying results in relation to clinicopathological characteristics and data on outcomes is limited. This study was aimed to describe the clinicopathological characteristics and outcomes of histologically confirmed urothelial bladder malignancies and to compare with previous studies.Methods: A retrospective analysis of prospectively collected data of 314 newly diagnosed primary bladder malignancies between January-2007 and January-2017, was performed. After excluding the non-urothelial cancers, 289(92%) urothelial cancers (males=245, 84.8%, mean age = 65.4±SD10.9 years) were analysed. Data on clinical presentation, cystoscopic findings, histopathology and outcomes were studied.Results: The majority (87.9%, n=254) presented with haematuria with a median duration of symptoms of 1 month. Non-muscle invasive cancers were seen among 64.4% (pTa:n=87(30.1%),pT1:n=99(34.3%)). The pT1 high grade (pT1-HG) tumours were seen in 17.5%. Muscle invasive bladder cancer (MIBC) were seen in 35.6%(n=103). The majority were high grade tumours (n=156,54%). Urothelial MIBC were significantly associated with solid tumours (p<0.001), high grade (p<0.001) and size>3cm (p<0.001). Comparison with previous studies showed a decline in the proportion of MIBC while the pT1-HG tumours are on the rise. Of those followed up, 52.5% developed recurrences with a median duration of 4 months (interquartile range (IQR): 3-12 months). Eighteen (9%) progressed to a higher stage with a median duration of 17 months (IQR:3.75-41.75).Conclusions: Urothelial cancer in the study population was 92%. Higher proportion of MIBC, high grade tumours and pT1-HG tumours were noted. The recurrence rate was high. Future studies should focus on the causative factors for this trend.","PeriodicalId":9777,"journal":{"name":"Ceylon Medical Journal","volume":"65 4","pages":"105-111"},"PeriodicalIF":0.4,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39657143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Screening for performance enhancing substances and quantification of ethanol in different Arishta manufactured in Sri Lanka. 斯里兰卡产阿利什塔中性能增强物质的筛选及乙醇的定量分析。

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Ceylon Medical Journal Pub Date : 2020-12-31 DOI: 10.4038/cmj.v65i4.9282

Nilu Fernando, Shehani Pigera, Nimesha Rashani, Ravindra Fernando, Pabasara Weerasinghe, Deepal Godakumbura, Madunil Niriella, Seevali Jayawickreme, Arjuna De Silva

{"title":"Screening for performance enhancing substances and quantification of ethanol in different Arishta manufactured in Sri Lanka.","authors":"Nilu Fernando, Shehani Pigera, Nimesha Rashani, Ravindra Fernando, Pabasara Weerasinghe, Deepal Godakumbura, Madunil Niriella, Seevali Jayawickreme, Arjuna De Silva","doi":"10.4038/cmj.v65i4.9282","DOIUrl":"https://doi.org/10.4038/cmj.v65i4.9282","url":null,"abstract":"Background: Arishta have been used in Ayurveda medicine for over thousands of years in Sri Lanka to treat various diseases. Ashwagandharishta, Balarishta and Dashamoolarishta are usually prescribed to obtain an anabolic effect, and Ashwagandharishta and Dashamoolarishta for androgenic effect in males. Thus, these arishta have been shown to have similar effect as anabolic androgenic steroids and stimulants in Western medicine. Therefore, arishta could potentially be used by athletes to improve their performance in sports leading to unintentional doping. Additionally, ethanol develops in-source during arista fermentation, which can affect athletes health.Objective: The aim of this study is to investigate whether the anabolic androgenic steroids or stimulants banned by World Anti-Doping Agency are present in these arishta, and to determine their ethanol content.Methods: Methanol extractions of Ashwagandarishta, Balarishta, Dashamoolarishta from four different manufacturers were screened for 21 stimulant and 22 anabolic androgenic steroids banned by World Anti-Doping Agency, using Gas Chromatography Mass Spectrometer. Ethanol content of the twelve Arishta samples were also measured.Results: Anabolic androgenic steroids or stimulants were not present in the tested Arishta samples, and percentage volume / volume ethanol content of all Arishta was between (5.80-8.35) ±0.5.Conclusion: The tested brands of Ashwagandharishta, Balarishta and Dashamoolarishta did not contain stimulants or anabolic androgenic steroids banned by World Anti-Doping Agency.","PeriodicalId":9777,"journal":{"name":"Ceylon Medical Journal","volume":"65 4","pages":"112-117"},"PeriodicalIF":0.4,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39928043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sleep quality assessment among college students using Pittsburgh Sleep Quality Index in a municipal corporation area of Uttarakhand, India. 利用匹兹堡睡眠质量指数对印度北阿坎德邦某市政企业地区大学生的睡眠质量进行评估。

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Ceylon Medical Journal Pub Date : 2020-12-31 DOI: 10.4038/cmj.v65i4.9279

Ranjeeta Kumari, Kapil Jain, Bhola Nath

{"title":"Sleep quality assessment among college students using Pittsburgh Sleep Quality Index in a municipal corporation area of Uttarakhand, India.","authors":"Ranjeeta Kumari, Kapil Jain, Bhola Nath","doi":"10.4038/cmj.v65i4.9279","DOIUrl":"https://doi.org/10.4038/cmj.v65i4.9279","url":null,"abstract":"Introduction: Poor sleep quality have been reported among adults in most countries and are increasingly been reported in their predecessors, the college students. The present study aimed to assess sleep patterns and determine its association with various correlates amongst college students for effective and timely interventions in the habit-forming years of the life.Methodology: This was a cross sectional study done among college students enrolled in different courses, in Rishikesh municipal corporation area, in Dehradun district of Uttarakhand, India. Sleep Quality was assessed using a validated Pittsburgh Sleep Quality Index (PSQI), which has seven components while Perceived Stress Scale-10 assessed Stress.Results: Poor sleep quality was reported among 66% of respondents. Mean sleep latency among respondents was 27.2 minutes (SD 20.75 min), with a median and mode of 20 minutes and 60 minutes respectively.On logistic regression analysis, yoga/ meditation, which have been recognized as effective relaxation techniques since ages, were found to have a positive association with better sleep quality (OR 0.47, 95% CI (0.26 - 0.84). Stress (OR 4.10, 95% CI 1.71- 9.83) and mobile use before bedtime (OR 1.956, 95% CI: 1.02- 3.75) were also significant predictors of poor sleep quality.Conclusions and recommendations: The prevalence of poor sleep quality was quite high. Relaxation techniques such as yoga/ meditation and stress relieving workshops may pay rich dividends. Use of electronic devices before bedtime need to be restricted for better sleep quality.","PeriodicalId":9777,"journal":{"name":"Ceylon Medical Journal","volume":"65 4","pages":"86-94"},"PeriodicalIF":0.4,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39657141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Complete primary pachydermoperiostosis. 完全性原发性厚皮积膜病。

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Ceylon Medical Journal Pub Date : 2020-12-31 DOI: 10.4038/cmj.v65i4.9283

Nilusha Weerasooriya, Amanda Amarasinghe, Lakshmina Punniyamoorthy, Harindra Karunatilake, Ananda Jayanaga

引用次数: 2

Association of Staphylococcus aureus nasal colonisation and mobile phone contamination in a Sri Lankan hospital. 斯里兰卡一家医院中金黄色葡萄球菌鼻腔定植与手机污染的关系。

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Ceylon Medical Journal Pub Date : 2020-12-31 DOI: 10.4038/cmj.v65i4.9285

Ishara Karunarathna, Nethmini Wedage, Shamini Wickrama, Chamara Senaratna, Kamani Gunasekera

引用次数: 1

Clinical management of dengue infection in pregnancy. 妊娠期登革热感染的临床管理。

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Ceylon Medical Journal Pub Date : 2020-12-31 DOI: 10.4038/cmj.v65i4.9275

Hasitha Tissera, Ananda Wijewickrama, Jayantha Weeraman, Azhar Ghouse, Athula Kaluarachchi, LakKumar Fernando, Anula Wijesundere

引用次数: 2

Comparison of glycaemic control and anthropometric parameters before and after Ramadan fasting in a selected cohort of patients with type 2 diabetes mellitus in Sri Lanka. 斯里兰卡2型糖尿病患者斋月禁食前后血糖控制和人体测量参数的比较

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Ceylon Medical Journal Pub Date : 2020-12-31 DOI: 10.4038/cmj.v65i4.9276

Mohamed Shafras, Lakshika Monaragala, Isha Samarakkody, Rafeek Ahamed, Lakshika Nawarathna, Mohamed Sanas, Charles Antonypillai

{"title":"Comparison of glycaemic control and anthropometric parameters before and after Ramadan fasting in a selected cohort of patients with type 2 diabetes mellitus in Sri Lanka.","authors":"Mohamed Shafras, Lakshika Monaragala, Isha Samarakkody, Rafeek Ahamed, Lakshika Nawarathna, Mohamed Sanas, Charles Antonypillai","doi":"10.4038/cmj.v65i4.9276","DOIUrl":"https://doi.org/10.4038/cmj.v65i4.9276","url":null,"abstract":"Introduction: The majority of Sri Lankan Moors fast during Ramadan. This may have an effect on their glycaemic control and anthropometric parameters. However, limited information exists about the impact of Ramadan fasting on diabetes in Sri Lanka.Objectives: The main objective of this study was to investigate the effect of Ramadan fasting on glycaemic control and anthropometric parameters in patients with type 2 diabetes mellitus (T2DM). Patients were also observed for symptoms of hypoglycaemia, timing and association with different antidiabetic agents.Methods: One hundred and twenty Sri Lankan Moors with T2DM were recruited for this study. Biochemical investigations and anthropometric parameters were done before and after Ramadan fasting. The statistical analysis was done with paired t test to compare glycaemic control and anthropometric parameters before and after Ramadan.Results: There was a significant decrease in body weight (mean body weight 66.17 to 65.52 kg; p= < 0.001) and waist circumference (93.84 to 92.16cm; p= < 0.001). However, the glycaemic control worsened in all patients during Ramadan with rise in mean fructosamine value of 354.1 to 996.9µmol/L. Out of 104 participants 43 participants experienced symptoms of hypoglycaemia.Conclusions: The current study showed an improvement in the body weight and waist circumference during Ramadan fasting, however the glycaemic control has been worsened. More follow-up studies are warranted in order to draw a conclusion on the effect of Ramadan fasting in glycaemic control and anthropometric parameters in diabetes patients.","PeriodicalId":9777,"journal":{"name":"Ceylon Medical Journal","volume":"65 4","pages":"79-85"},"PeriodicalIF":0.4,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39657140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Analysis of common genetic mutations in a cohort of children with salt wasting form of Congenital Adrenal Hyperplasia. 盐消耗型先天性肾上腺增生儿童队列常见基因突变分析。

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Ceylon Medical Journal Pub Date : 2020-12-31 DOI: 10.4038/cmj.v65i4.9280

Praveenan Somasundaram, Sudeshini Hewage, Harshini De Silva

{"title":"Analysis of common genetic mutations in a cohort of children with salt wasting form of Congenital Adrenal Hyperplasia.","authors":"Praveenan Somasundaram, Sudeshini Hewage, Harshini De Silva","doi":"10.4038/cmj.v65i4.9280","DOIUrl":"https://doi.org/10.4038/cmj.v65i4.9280","url":null,"abstract":"Introduction: Steroid hydroxylase deficiency due to CYP21A2 gene mutation is the most common cause of Congenital Adrenal Hyperplasia (CAH). Mutation spectrum in Sri Lankan CAH patients has not been investigated adequately.Objectives: This study attempted to study the spectrum of mutations in CYP21A2 gene in 30 patients with salt wasting form of CAH in Sri Lanka.Methods: Allele specific polymerase chain reaction was carried out using mutation site specific primers for eight mutations (P30L, I2G, 8bp deletion, I172N, E6 cluster, V281L, Q318X and R356W) reported as frequently occurring in other populations.Results: Fourteen patients had homozygous mutations; six patients were compound heterozygotes as determined by investigating parents of the patients, one patient had a large gene deletion which was previously reported and the remaining patients had at least one heterozygous mutation. The following allele frequencies were observed for each mutation P30L-10%, I2G- 40%, 8bp-18.33%, I172N-3.33%, E6 cluster- 5%, Q318X-40% and R356W-3.33%. V281L mutation was not observed in the study cohort. DNA sequencing revealed a novel mutation G292S in one patient.Conclusion: This is the first report describing a broad spectrum of mutations in CYP21A2 gene in Sri Lankan patients with CAH. Mutation frequencies did not vary from other ethnic groups reported around the world.","PeriodicalId":9777,"journal":{"name":"Ceylon Medical Journal","volume":"65 4","pages":"95-104"},"PeriodicalIF":0.4,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39657142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0