CEN Case Reports最新文献_第10页

Takayasu arteritis-associated refractory hypertension induces nephrotic syndrome through glomerular microangiopathy. 高须动脉炎相关的难治性高血压通过肾小球微血管病变诱发肾病综合征。

IF 1

CEN Case Reports Pub Date : 2024-12-09 DOI: 10.1007/s13730-024-00952-5

Tomoya Nakayamada, Kensei Taguchi, Chikei Natori, Nao Nakamura, Makiko Fujii, Yuya Yamashita, Sakuya Ito, Kei Fukami

引用次数: 0

Ceftriaxone encephalopathy in a very elderly dialysis patient. 头孢曲松脑病在老年透析患者中的应用。

IF 1

CEN Case Reports Pub Date : 2024-12-09 DOI: 10.1007/s13730-024-00953-4

Yumiko Nakamura, Ryo Yamamoto, Yuya Shioda, Takatsugu Iwashita, Taisuke Shimizu, Akito Maeshima, Hajime Hasegawa, Tomonari Ogawa

{"title":"Ceftriaxone encephalopathy in a very elderly dialysis patient.","authors":"Yumiko Nakamura, Ryo Yamamoto, Yuya Shioda, Takatsugu Iwashita, Taisuke Shimizu, Akito Maeshima, Hajime Hasegawa, Tomonari Ogawa","doi":"10.1007/s13730-024-00953-4","DOIUrl":"https://doi.org/10.1007/s13730-024-00953-4","url":null,"abstract":"Ceftriaxone is widely used clinically but it can potentially cause ceftriaxone encephalopathy in individuals who are on dialysis. We describe ceftriaxone encephalopathy in a dialysis patient. The 87-year-old Japanese woman had a 9-year dialysis history. She was admitted to our department with right subcostal pain and lower back pain and was diagnosed with renal cyst hemorrhage and infection. Post-admission, we treated her with ceftriaxone (CTRX) 2 g/day and bed rest, which improved her symptoms. On the 7th hospitalization day, she began to exhibit incoherent speech and unresponsiveness; by day 10, her consciousness level had decreased to grade III and myoclonus appeared. Brain MRI and a cerebrospinal fluid examination ruled out cerebrovascular disease and encephalitis. EEG showed triphasic waves predominantly in the frontal lobe. Suspecting ceftriaxone encephalopathy, we switched the antibiotic to cefazolin 1 g/day. By day 12, the myoclonus decreased and the patient was able to communicate. By day 14, her consciousness level had improved to her admission level. We treated ceftriaxone encephalopathy in a dialysis patient. Although CTRX is generally thought to not require dose reduction in patients with renal failure (due to its hepatic excretion), caution is necessary as overdosage in dialysis patients can lead to myoclonus and encephalopathy.","PeriodicalId":9697,"journal":{"name":"CEN Case Reports","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142799422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The natural history of untreated X-linked nephrogenic diabetes insipidus with mutation in the vasopressin V2 receptor gene. 抗利尿激素V2受体基因突变的未经治疗的x连锁肾源性尿崩症的自然历史。

IF 1

CEN Case Reports Pub Date : 2024-12-07 DOI: 10.1007/s13730-024-00954-3

Giusy Capasso, Stefano Guarino, Anna Di Sessa, Margherita Luciano, Emanuele Miraglia Del Giudice, Francesco Trepiccione, Pierluigi Marzuillo

{"title":"The natural history of untreated X-linked nephrogenic diabetes insipidus with mutation in the vasopressin V2 receptor gene.","authors":"Giusy Capasso, Stefano Guarino, Anna Di Sessa, Margherita Luciano, Emanuele Miraglia Del Giudice, Francesco Trepiccione, Pierluigi Marzuillo","doi":"10.1007/s13730-024-00954-3","DOIUrl":"https://doi.org/10.1007/s13730-024-00954-3","url":null,"abstract":"Nephrogenic diabetes insipidus (NDI) results from the kidneys' inability to concentrate urine. We describe a 6-month-old male with a history of poor weight gain who presented with an incidental finding of hypernatremia (155 mEq/L) during an episode of acute gastroenteritis. The arginine vasopressin (AVP) test, along with molecular analysis revealing the M272R mutation in the AVP receptor 2 (AVPR2) gene, confirmed the diagnosis of congenital NDI. Interestingly, this mutation was also identified in the patient's maternal grandfather, who had never been diagnosed or treated for NDI despite a history of polydipsia, polyuria, and evidence of chronic kidney disease (CKD), severe bilateral hydronephrosis, hypertension, and severe bladder dysfunction. Early intervention with hydrochlorothiazide in the infant resulted in a significant reduction in urinary output and improved growth. The untreated grandfather's case highlights the potential severity of untreated NDI and the benefits of timely therapeutic intervention. This report contributes to the limited long-term data on congenital NDI, emphasizing the critical role of early detection and consistent management in preventing severe complications such as CKD, hydronephrosis, and bladder dysfunction. Regular follow-up, including renal ultrasound and monitoring of renal function, is essential for effectively managing NDI and improving patient outcomes.","PeriodicalId":9697,"journal":{"name":"CEN Case Reports","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142791173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A case of hypertensive emergency with alveolar hemorrhage and thrombotic microangiopathy. 一例伴有肺泡出血和血栓性微血管病的高血压急症。

IF 1

CEN Case Reports Pub Date : 2024-12-01 Epub Date: 2024-03-28 DOI: 10.1007/s13730-024-00863-5

Yoshifumi Ubara, Shigekazu Kurihara, Yoshiki Tsuchiya, Yuki Oba, Daisuke Ikuma, Hiroki Mizuno, Masayuki Yamanouchi, Tatsuya Suwabe, Atsuko Imase, Nobumitsu Shibata, Kei Kono, Keiichi Kinowaki, Kenichi Ohashi, Kentaro Ogata, Naoki Sawa

引用次数: 0

De novo posttransplant membranous nephropathy after COVID-19 vaccination 9 years after renal transplantation in a patient with polycystic kidney disease. 一名多囊肾患者在肾移植 9 年后接种 COVID-19 疫苗后出现移植后膜性肾病。

IF 1

CEN Case Reports Pub Date : 2024-12-01 Epub Date: 2024-03-23 DOI: 10.1007/s13730-024-00864-4

Miruzato Fukuda, Takayoshi Yokoyama, Katsuyuki Miki, Masayuki Yamanouchi, Daisuke Ikuma, Hiroki Mizuno, Yuki Oba, Noriko Inoue, Akinari Sekine, Kiho Tanaka, Eiko Hasegawa, Tatsuya Suwabe, Takehiko Wada, Kei Kono, Keiichi Kinowaki, Kenichi Ohashi, Yutaka Yamaguchi, Yuki Nakamura, Yasuo Ishii, Naoki Sawa, Yoshifumi Ubara

{"title":"De novo posttransplant membranous nephropathy after COVID-19 vaccination 9 years after renal transplantation in a patient with polycystic kidney disease.","authors":"Miruzato Fukuda, Takayoshi Yokoyama, Katsuyuki Miki, Masayuki Yamanouchi, Daisuke Ikuma, Hiroki Mizuno, Yuki Oba, Noriko Inoue, Akinari Sekine, Kiho Tanaka, Eiko Hasegawa, Tatsuya Suwabe, Takehiko Wada, Kei Kono, Keiichi Kinowaki, Kenichi Ohashi, Yutaka Yamaguchi, Yuki Nakamura, Yasuo Ishii, Naoki Sawa, Yoshifumi Ubara","doi":"10.1007/s13730-024-00864-4","DOIUrl":"10.1007/s13730-024-00864-4","url":null,"abstract":"A 63-year-old man with polycystic kidney disease underwent kidney transplantation from his wife. Nine years later, after the first and second doses of the COVID-19 vaccination, he developed proteinuria, hematuria, and elevated C-reactive protein. Kidney biopsy 7 months after the initial appearance of proteinuria showed immunoglobulin (Ig)-G granular stain, predominantly IgG1, and spike formation in the glomerular basement membrane. Electron microscopy revealed mainly subepithelial deposits, which corresponds to membranous nephropathy (MN) stage 3 of the Ehrenreich-Churg classification indicating chronic disease, but it also showed electron-dense deposits and endothelial damage. Because a kidney biopsy was performed 1 h after renal transplantation and a biopsy of the patient's native kidney showed intact glomeruli, atypical de novo posttransplant membranous nephropathy (MN) was diagnosed, and a close relationship with COVID-19 vaccination was assumed. Clinicians should consider the involvement of COVID-19 vaccination in de novo posttransplant MN with unclear pathogenesis.","PeriodicalId":9697,"journal":{"name":"CEN Case Reports","volume":" ","pages":"434-439"},"PeriodicalIF":1.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11608188/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140193478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Acquired Bartter-like syndrome associated with colistin use in an adult patient: a case report. 与一名成年患者使用可乐定有关的获得性巴特样综合征：病例报告。

IF 1

CEN Case Reports Pub Date : 2024-12-01 Epub Date: 2024-05-21 DOI: 10.1007/s13730-024-00891-1

Ameneh Sari, Mohammadreza Fadavipour, Samaneh Hashemi

{"title":"Acquired Bartter-like syndrome associated with colistin use in an adult patient: a case report.","authors":"Ameneh Sari, Mohammadreza Fadavipour, Samaneh Hashemi","doi":"10.1007/s13730-024-00891-1","DOIUrl":"10.1007/s13730-024-00891-1","url":null,"abstract":"Colistin is an effective antibiotic utilized for the treatment of Gram-negative bacterial infections with coverage against a broad spectrum of bacteria. Despite the broad antibacterial coverage, this antibiotic can have serious complications such as acute kidney injury. Colistin also can have a toxic effect on the loop of Henle, causing tubulopathy, electrolyte imbalances, and the occurrence of Bartter-like syndrome (BLS) which is characterized by magnesium and calcium disturbances, polyuria, and metabolic alkalosis. We here report a 32-year-old male with a history of multiple trauma due to an accident that received colistin therapy for Pseudomonas isolation from wound culture on the 5th day of hospitalization. Polyuria, hypokalemic metabolic alkalosis, hypomagnesemia, and hypocalcemia were developed on the first week of colistin administration. The patient received colistin until the 21st day of hospitalization. Serum calcium and magnesium levels became normal 1 day after stopping colistin, while urine volume and metabolic alkalosis resolved 6 days after colistin discontinuing. Therefore, it is crucial to adjust the dose of colistin to minimize its toxicity.","PeriodicalId":9697,"journal":{"name":"CEN Case Reports","volume":" ","pages":"557-560"},"PeriodicalIF":1.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11608191/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141069631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Widespread form of Majocchi's granuloma in a kidney transplant recipient. 肾移植受者身上广泛分布的马约奇肉芽肿。

IF 1

CEN Case Reports Pub Date : 2024-12-01 Epub Date: 2024-05-20 DOI: 10.1007/s13730-024-00883-1

Cihan Uysal, Hanife Oguz, Hasan Cifci, Ismail Kocyigit

{"title":"Widespread form of Majocchi's granuloma in a kidney transplant recipient.","authors":"Cihan Uysal, Hanife Oguz, Hasan Cifci, Ismail Kocyigit","doi":"10.1007/s13730-024-00883-1","DOIUrl":"10.1007/s13730-024-00883-1","url":null,"abstract":"Kidney transplantation is the encouraged kidney replacement therapy due to providing more prolonged survival with a better quality of life. Unfortunately, kidney transplant recipients are susceptible to infections because of long-term utilization of immunosuppression. Despite dermatophyte infections are generally not life-threatening, the clinical significance has been recently enhanced by an increasing number of immunocompromised patients. We have presented a rare dermatophytosis course, Majocchi's granuloma, that spreads to all extremities during the early post-transplant period. A young kidney transplant recipient was exposed to intensive immunosuppression therapy due to acute rejection in the early period of post-transplantation. After four months, numerous nodular skin lesions were raised on various body parts. An invasive fungal infection was identified in the skin biopsy. Also, Trichophyton rubrum was isolated in the tissue cultures. Consequently, the patient was diagnosed with Majocchi's granuloma. An effectual treatment was attained with an oral terbinafine tablet. Majocchi's granuloma is a distinct form of dermatophytosis characterized by the spreading of infection into the dermis. In this unexpected case, we alerted physicians to opportunistic infections in the kidney transplant recipient.","PeriodicalId":9697,"journal":{"name":"CEN Case Reports","volume":" ","pages":"552-556"},"PeriodicalIF":1.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11608206/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141065244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Positive response of a hemodialysis patient with pure red cell aplasia on recombinant human erythropoietin therapy to cyclosporine and Roxadustat. 一名纯红细胞再生不良的血液透析患者在接受重组人促红细胞生成素治疗后，对环孢素和罗沙司他产生了积极反应。

IF 1

CEN Case Reports Pub Date : 2024-12-01 Epub Date: 2024-03-25 DOI: 10.1007/s13730-024-00865-3

Xuejuan Ma, Pearl Pai, Wenjuan Zhu, Xiaowei Chen, Liwen Cui

{"title":"Positive response of a hemodialysis patient with pure red cell aplasia on recombinant human erythropoietin therapy to cyclosporine and Roxadustat.","authors":"Xuejuan Ma, Pearl Pai, Wenjuan Zhu, Xiaowei Chen, Liwen Cui","doi":"10.1007/s13730-024-00865-3","DOIUrl":"10.1007/s13730-024-00865-3","url":null,"abstract":"Recombinant human erythropoietin (rHuEPO) is commonly used to treat anemia associated with chronic kidney disease (CKD). EPO-induced Pure Red Cell Aplasia (PRCA) is a rare condition of profound anemia with EPO treatment. Upon finding the development of EPO-induced PRCA, the treatment requires immediate withdrawal of EPO therapy and initiate new treatments with immunosuppression or renal transplantation. Anti-EPO antibody assay is not always positive in EPO-induced PRCA. Here, we report a case on the sudden development of PRCA in a hemodialysis patient receiving EPO and how we treated the condition successfully with cyclosporine and subsequently maintained the hemoglobin with Roxadustat, a hypoxia-inducible factor prolyl hydroxylase inhibitor (HIF-PHI). Even though the anti-EPO antibody was negative by Enzyme Linked Immunosorbent Assay (ELISA) in our case, the clinical course, the markedly reduced reticulocyte count < 10,000/μL, the bone marrow (BM) biopsy revealing reduced erythroblasts, and its subsequent response to cyclosporine, were similar to EPO-induced PRCA. The clinical picture of EPO-induced PRCA, the limitation of the EPO-neutralizing antibody (Ab) assay, and treatment strategies were discussed.","PeriodicalId":9697,"journal":{"name":"CEN Case Reports","volume":" ","pages":"445-449"},"PeriodicalIF":1.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11608189/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140287065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Transcatheter renal arterial embolization for intractable urinary fistula occurring after robot-assisted partial nephrectomy: a case report. 经导管肾动脉栓塞治疗机器人辅助肾部分切除术后发生的顽固性尿瘘：病例报告。

IF 1

CEN Case Reports Pub Date : 2024-12-01 Epub Date: 2024-03-19 DOI: 10.1007/s13730-024-00866-2

Yoshiaki Kawamura, Takato Uchida, Tatsuo Kano, Tatsuya Umemoto, Nobuyuki Nakajima, Masahiro Nitta, Masanori Hasegawa, Sunao Shoji, Akira Miyajima

{"title":"Transcatheter renal arterial embolization for intractable urinary fistula occurring after robot-assisted partial nephrectomy: a case report.","authors":"Yoshiaki Kawamura, Takato Uchida, Tatsuo Kano, Tatsuya Umemoto, Nobuyuki Nakajima, Masahiro Nitta, Masanori Hasegawa, Sunao Shoji, Akira Miyajima","doi":"10.1007/s13730-024-00866-2","DOIUrl":"10.1007/s13730-024-00866-2","url":null,"abstract":"Partial nephrectomy is the standard surgical procedure for small renal tumors. Since the advent of robot-assisted partial nephrectomy (RAPN), the number of cases of renal tumors undergoing the procedure has increased exponentially. Urinary fistula is a complication of partial nephrectomy. Conservative management using ureteral stents is useful in most cases of urinary fistulas. However, some patients develop intractable urinary fistulas. Herein, we report a case in which vascular embolization was useful for treating an infected and intractable urinary fistula that developed after RAPN. A 59-year-old man was accidentally found to have a right renal tumor (approximately 3 cm in diameter) during a physical examination. Pathology was clear cell carcinoma. RAPN was performed owing to the small size of the renal tumor; however, postoperatively, an intractable urinary fistula with an isolated calyx developed, which was successfully treated with transcatheter renal arterial embolization (TAE). We encountered a rare case of infected refractory urinary fistula with an isolated calyx in which TAE was successful. TAE seems useful in treating intractable urinary fistulas with an isolated calyx occurring after RAPN.","PeriodicalId":9697,"journal":{"name":"CEN Case Reports","volume":" ","pages":"425-428"},"PeriodicalIF":1.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11608192/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140173783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Urinary liver-type fatty acid-binding protein level as a prognostic indicator of acute kidney injury secondary to severe falciparum malaria. 尿液肝T型脂肪酸结合蛋白水平作为严重恶性疟原虫疟疾继发急性肾损伤的预后指标。

IF 1

CEN Case Reports Pub Date : 2024-12-01 Epub Date: 2024-05-10 DOI: 10.1007/s13730-024-00886-y

Yuri Katayama, Keiki Shimada, Daisuke Katagiri, Kanako Terakawa, Emi Sakamoto, Takahito Niikura, Minami Suzuki, Yuki Yoshizaki, Lubna Sato, Gen Yamada, Yutaro Akiyama, Sekiko Taneda, Hideki Takano

{"title":"Urinary liver-type fatty acid-binding protein level as a prognostic indicator of acute kidney injury secondary to severe falciparum malaria.","authors":"Yuri Katayama, Keiki Shimada, Daisuke Katagiri, Kanako Terakawa, Emi Sakamoto, Takahito Niikura, Minami Suzuki, Yuki Yoshizaki, Lubna Sato, Gen Yamada, Yutaro Akiyama, Sekiko Taneda, Hideki Takano","doi":"10.1007/s13730-024-00886-y","DOIUrl":"10.1007/s13730-024-00886-y","url":null,"abstract":"Acute kidney injury (AKI) secondary to severe falciparum malaria possesses a high mortality rate; however, a prognostic marker of renal dysfunction has not yet been identified. Thus, we reported a case of a patient with AKI secondary to falciparum malaria who underwent hemodialysis and a renal biopsy due to prolonged renal dysfunction. The male patient, in his 50 s, presented to our hospital with vomiting, diarrhea, fever, and decreased level of consciousness. The Giemsa-stained peripheral blood film revealed approximately 5% parasitemia, and a rapid diagnostic test was positive for Plasmodium falciparum. He was diagnosed with severe falciparum malaria and was started on quinine hydrochloride. Hemodialysis was initiated due to the decreased urine output and fluid retention. Subsequently, he was weaned off hemodialysis. The histopathological analysis of a renal biopsy revealed interstitial fibrosis, tubular atrophy, and chronic inflammatory cell infiltration; thus, malarial nephropathy was diagnosed. Thereafter, his renal function stabilized, and he was discharged from the hospital. The urinary liver-type fatty acid-binding protein (L-FABP) level decreased before renal function improved. Our report highlighted that long-term follow-up is essential for severe AKI secondary to malaria. The urinary L-FABP level may be a useful prognostic indicator of AKI secondary to severe falciparum malaria.","PeriodicalId":9697,"journal":{"name":"CEN Case Reports","volume":" ","pages":"522-527"},"PeriodicalIF":1.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11608179/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140897461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0