Serkan Aslan, Gamze Babur Guler, Ahmet Arif Yalcin, Mehmet Erturk
{"title":"Successful Management of an Atrial Embolized Valve During Transcatheter Tricuspid Valve-in-Ring Implantation With a Novel Technique: A Case Report.","authors":"Serkan Aslan, Gamze Babur Guler, Ahmet Arif Yalcin, Mehmet Erturk","doi":"10.1002/ccd.31602","DOIUrl":"https://doi.org/10.1002/ccd.31602","url":null,"abstract":"<p><p>Transcatheter tricuspid valve-in-ring implantation (TVIRI) has emerged as a viable therapy for high-risk patients with symptomatic severe tricuspid regurgitation after failure of tricuspid annuloplasty. However, there are potential complications associated with this minimally invasive procedure, including the rare but life-threatening occurrence of valve embolization during TVIRI. This report describes a rare case of atrial embolization of a balloon-expandable valve during TVIRI in a 67-year-old female patient. The embolized valve was successfully retrieved and repositioned with a balloon catheter, avoiding emergent surgery. This case illustrates a novel management strategy for valve embolization and provides valuable insight into the expanding field of structural heart interventions.</p>","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144092281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Selina Vlieger, Jin M Cheng, Filippo Luca Gurgoglione, Tay M Heang, Alexander J J Ijsselmuiden, Alfonso Ielasi, Eric Boersma, Lee C Yan, Alessandro Sciahbasi, Ramesh Singh, George Karavolias, Dario Gattuso, Rohit M Oemrawsingh, Bernardo Cortese
{"title":"Comparison of Sirolimus-Versus Paclitaxel-Coated Balloons in Coronary Artery Disease: One-Year Results of Two Real-World Prospective Registries.","authors":"Selina Vlieger, Jin M Cheng, Filippo Luca Gurgoglione, Tay M Heang, Alexander J J Ijsselmuiden, Alfonso Ielasi, Eric Boersma, Lee C Yan, Alessandro Sciahbasi, Ramesh Singh, George Karavolias, Dario Gattuso, Rohit M Oemrawsingh, Bernardo Cortese","doi":"10.1002/ccd.31587","DOIUrl":"https://doi.org/10.1002/ccd.31587","url":null,"abstract":"<p><strong>Background: </strong>Paclitaxel-(PCB) and sirolimus-coated balloons (SCB) are used for treatment of in-stent restenosis (ISR) and de novo (DN) lesions. Studies comparing major adverse cardiac events (MACE) after PCB versus SCB are limited.</p><p><strong>Aims: </strong>This study aims to contribute to this knowledge gap and enhance the understanding of optimal strategies for treating ISR and DN lesions.</p><p><strong>Methods: </strong>EASTBOURNE and PEARL are large-scale, prospective clinical registries, evaluating the performance of drug-coated balloons. PEARL included patients who underwent percutaneous coronary intervention using Protege PCB and EASTBOURNE included patients treated with MagicTouch SCB in study centers in Europe and Asia. We combined these registries and used logistic regression analysis to assess the association between SCB/PCB and the likelihood of experiencing MACE, a composite of all-cause mortality, myocardial infarction (MI) and target-lesion revascularisation (TLR) at 1-year follow-up.</p><p><strong>Results: </strong>Out of 2596 patients, MACE was observed more frequently in ISR lesions (n = 1292 patients, SCB:17.8% vs. PCB:14.1%, p = 0.12) versus DN lesions (n = 1304 patients, SCB:6.4% vs. PCB:6.1%, p = 1.00). The adjusted hazards ratio (HR) for MACE was 1.17 (95% CI: 0.59-1.23, p = 0.40). As regards DN lesions, no significant difference was found in MACE (SCB: 6.4% vs. PCB 6.1%, p = 1.00). The adjusted HR for MACE was 1.24 (95% CI: 0.20-2.01, p = 0.13). There were no differences in the individual components of the primary endpoint.</p><p><strong>Conclusions: </strong>This real-world comparison demonstrated comparable outcomes between new-generation PCB and SCB in terms of MACE at 1-year follow-up, across different lesion settings.</p>","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144092028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Small Balloon Low-Pressure Pullback Technique: A Novel Approach for Managing Coronary Intramural Hematoma During Percutaneous Coronary Intervention.","authors":"Chen Chen, Yaoxue Zang, Ziyi Ni, Yinuo Lin","doi":"10.1002/ccd.31597","DOIUrl":"https://doi.org/10.1002/ccd.31597","url":null,"abstract":"<p><p>A coronary intramural hematoma (CIMH) is a potentially life-threatening complication of percutaneous coronary intervention (PCI), often resulting in compromised distal blood flow. Traditional management strategies, including additional stenting, cutting balloon angioplasty, and conservative treatment, have shown inconsistent efficacy and may even exacerbate the condition. We present the small balloon low-pressure pullback (SBLP) technique, a novel approach designed for hematoma evacuation, involving gently squeezing and pulling the hematoma back toward the proximal segment, thereby restoring distal flow. In this case series, we report the successful application of the SBLP technique in four patients with CIMH during PCI. The Thrombolysis in Myocardial Infarction (TIMI) flow grade was used to determine the efficacy of the procedure. All four patients had TIMI III flow after the procedure, indicating complete restoration of distal blood flow. Our findings suggest that the SBLP technique is a promising, minimally invasive approach for managing CIMH, as it restores blood flow with minimal risk of iatrogenic injury. This technique may be an effective alternative to conventional management methods for CIMH. However, further research, including randomized controlled trials, is warranted to validate these results and establish the long-term efficacy and safety of the SBLP technique.</p>","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144092317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correction to \"12-Month Outcomes of Transcatheter Tricuspid Valve Repair With the Pascal System for Severe Tricuspid Regurgitation\".","authors":"","doi":"10.1002/ccd.31575","DOIUrl":"https://doi.org/10.1002/ccd.31575","url":null,"abstract":"","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Farhan Naeem, Shehroze Tabassum, Muhammad Burhan, Usama Qamar, M Chadi Alraies, Dmitry Abramov
{"title":"Dual ProGlide Versus ProGlide and Angio-Seal for Femoral Access Hemostasias in Transcatheter Aortic Valve Replacement: A Meta-Analysis of Up-to-Date Evidence.","authors":"Farhan Naeem, Shehroze Tabassum, Muhammad Burhan, Usama Qamar, M Chadi Alraies, Dmitry Abramov","doi":"10.1002/ccd.31577","DOIUrl":"https://doi.org/10.1002/ccd.31577","url":null,"abstract":"","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Deniz Mutlu, Pedro E P Carvalho, Ozgur Selim Ser, Dimitrios Strepkos, Michaella Alexandrou, Barkin Kultursay, Ali Karagoz, Oleg Krestyaninov, Dmitrii Khelimskii, Mahmut Uluganyan, Korhan Soylu, Ufuk Yildirim, Seda Tanyeri Uzel, Mehmet Semih Belpinar, Olga Mastrodemos, Bavana V Rangan, Sandeep Jalli, Jas D Sara, Konstantinos Voudris, Yader Sandoval, M Nicholas Burke, Emmanouil S Brilakis
{"title":"Impact of Isolated Side Branch Lesions on Procedural Techniques and Outcomes of Bifurcation Percutaneous Coronary Intervention.","authors":"Deniz Mutlu, Pedro E P Carvalho, Ozgur Selim Ser, Dimitrios Strepkos, Michaella Alexandrou, Barkin Kultursay, Ali Karagoz, Oleg Krestyaninov, Dmitrii Khelimskii, Mahmut Uluganyan, Korhan Soylu, Ufuk Yildirim, Seda Tanyeri Uzel, Mehmet Semih Belpinar, Olga Mastrodemos, Bavana V Rangan, Sandeep Jalli, Jas D Sara, Konstantinos Voudris, Yader Sandoval, M Nicholas Burke, Emmanouil S Brilakis","doi":"10.1002/ccd.31601","DOIUrl":"https://doi.org/10.1002/ccd.31601","url":null,"abstract":"<p><strong>Background: </strong>There is limited information on the impact of the isolated side branch lesions (ISBL) on the procedural techniques and outcomes of bifurcation percutaneous coronary intervention (PCI).</p><p><strong>Aims: </strong>To examine the clinical, procedural and long-term outcomes of ISBL.</p><p><strong>Methods: </strong>We examined the clinical, angiographic characteristics, and procedural outcomes of 1719 bifurcation PCIs in 1501 patients between 2014 and 2023 from the PROGRESS-BIFURCATION registry. A propensity score matched (PSM) Cox proportional hazards model was used to assess long-term outcomes.</p><p><strong>Results: </strong>ISBL (Medina class 0,0,1) was present in 80 patients (5.3%). ISBL patients had similar baseline characteristics to the remaining patients, except for hypertension (90.0% vs. 79.2%, p = 0.020), prior PCI (66.3% vs. 44.5%, p < 0.001), and prior MI (50.6% vs. 35.2%, p = 0.006) that were more common in ISBL patients. ISBL had a median side branch diameter of 2.5 mm (interquartile range [IQR] 2.5-3.0), a median length of 10 mm (IQR 5-12), and a median side branch stenosis of 90% (IQR 80-95). The most common stenting strategies were side branch stenting (41.8%) and inverted provisional (25.5%). Technical and procedural success and in-hospital major adverse cardiovascular events (MACE) were similar in patients with and without ISBL. At 3-year follow-up, the incidence of MACE was higher in ISBL patients (36.3% vs. 26.4%, p = 0.043), driven by higher repeat target vessel PCI (26.8% vs. 12.0%; p = 0.003). On PSM adjusted Cox analysis, ISBL were independently associated with higher follow-up MACE (hazard ratio 1.58, 95% confidence intervals 1.13-2.20, p = 0.008).</p><p><strong>Conclusions: </strong>PCI of ISBL was infrequent and was associated with similar technical and procedural success with non-ISBL but higher long-term MACE driven by higher TVR.</p>","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143953758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Concerns Regarding Procedural and Safety Data in Immediate Versus Staged Revascularization Meta-Analysis.","authors":"Abdur Rehman","doi":"10.1002/ccd.31603","DOIUrl":"https://doi.org/10.1002/ccd.31603","url":null,"abstract":"","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Transcatheter Aortic Valve Replacement for Structural Valve Deterioration After Aortic Valve Neocuspidization.","authors":"Natsuko Satomi, Masaki Miyasaka, Yusuke Enta, Yoshiko Munehisa, Yusuke Toki, Masaki Nakashima, Makoto Saigan, Yuta Kobayashi, Yun Teng, Manabu Maeda, Momo Kosuga, Kazuo Abe, Masataka Taguri, Yukihiro Hayatsu, Masaki Hata, Norio Tada","doi":"10.1002/ccd.31583","DOIUrl":"https://doi.org/10.1002/ccd.31583","url":null,"abstract":"<p><strong>Background: </strong>Evidence on structural valve deterioration (SVD) after aortic valve neocuspidization (AVNeo) remains limited. While transcatheter aortic valve replacement (TAVR) offers a less invasive option, its feasibility is unclear. This study aimed to characterize SVD patients post-AVNeo and to assess TAVR feasibility.</p><p><strong>Methods: </strong>This retrospective study included 11 patients who underwent TAVR for SVD after AVNeo in Sendai Kousei Hospital between June 2017 and August 2024. Four patients with aortic stenosis (AS) and seven with aortic regurgitation (AR) due to SVD were included.</p><p><strong>Results: </strong>AS-SVD group showed shorter time interval from AVNeo to TAVR (50.5 [28.3-98.3] vs. 107.0 [97.0-131.0] months, p = 0.04) and smaller aortic annulus area (316.5 [259.8-375.0] vs. 538.0 [440.0-582.0] mm<sup>2</sup>, p = 0.005) than AR-SVD group. In TAVR, technical success was achieved in 91% of cases. Although coronary obstruction is a concern due to the long leaflet, no case occurred. Misidentification of the basal ring plane caused by the slack cusp resulted in second valve implantation (one case) and new conduction disturbance (two cases) due to deep implantation, and aortic contained rupture (one case) for oversized valve selection.</p><p><strong>Conclusions: </strong>Rapid AS-SVD progression and AR-SVD occurring later than previously reported were observed, highlighting the need for further studies on AVNeo durability. TAVR after AVNeo was feasible. Special precautions for coronary obstruction may be unnecessary. Careful hinge point placement at the boundary between pericardial cusps and the annulus was a key to CT-based basal ring determination in patients after AVNeo.</p>","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Antibiotic-Induced Gut Microbiome Dysbiosis Aggravates Cerebral Injury During Extracorporeal Membrane Oxygenation.","authors":"Kangmei Shao, Jian Li, Xueyang Shen, Mingming Li, Shilin Wei, Xiangyang Wu, Yongnan Li, Zhaoming Ge","doi":"10.1002/ccd.31589","DOIUrl":"https://doi.org/10.1002/ccd.31589","url":null,"abstract":"<p><strong>Background: </strong>Extracorporeal membrane oxygenation (ECMO) is an effective treatment for cardiopulmonary failure. However, it is associated with severe complications, including cerebral injury, which contribute to elevated mortality and disability rates. The administration of antibiotics may lead to gut microbiome dysbiosis among critically ill patients.</p><p><strong>Aims: </strong>This study aims to investigate the association between antibiotic-induced gut microbiome dysbiosis and cerebral injury during ECMO treatment.</p><p><strong>Methods: </strong>The compositional changes in the gut microbiome induced by antibiotic (ABX) treatment were analyzed using microbiome analysis techniques. ECMO treatment models were established by using rat. Brain tissue pathology was assessed using H&E and Nissl staining. Serum concentrations of S100β and NSE were quantified using ELISA. Pro-inflammatory factors in the brain and serum were analyzed, and microglial activation was evaluated via immunofluorescence.</p><p><strong>Results: </strong>Gut microbiome dysbiosis induced by ABX treatment. Compared to the sham group, significant cerebral injury was observed in both the ECMO and ECMO-ABX groups. The expression levels of S100β and NSE were significantly elevated in the ECMO-ABX group. Additionally, parameters of microglial activation, such as cell body area, total branch length, mean length of branches, and number of branch points, were significantly increased in the ECMO-ABX group compared to the ECMO group.</p><p><strong>Conclusions: </strong>This study demonstrates that cerebral injury occurs during ECMO treatment, and antibiotic-induced gut microbiome dysbiosis may exacerbate this cerebral injury.</p>","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143973585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}