Case Reports in Oncological Medicine最新文献_第8页

Thoracodorsal Artery Perforator Flap for Chronic Radiation-Induced Ulcer of the Axilla in Vietnam. 越南胸背动脉穿支皮瓣治疗慢性放射性腋窝溃疡。

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Case Reports in Oncological Medicine Pub Date : 2021-10-06 eCollection Date: 2021-01-01 DOI: 10.1155/2021/8478006

Hong Quang Le, Anh Dung Hoang

引用次数: 2

Sporadic Burkitt Lymphoma Presenting with Middle Cranial Fossa Masses with Sphenoid Bony Invasion and Acute Pancreatitis in a Child. 儿童散发性伯基特淋巴瘤表现为颅中窝肿块伴蝶骨侵犯并急性胰腺炎。

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Case Reports in Oncological Medicine Pub Date : 2021-09-14 eCollection Date: 2021-01-01 DOI: 10.1155/2021/6610666

Tal Dror, Virginia Donovan, Naomi Strubel, Sucharita Bhaumik

{"title":"Sporadic Burkitt Lymphoma Presenting with Middle Cranial Fossa Masses with Sphenoid Bony Invasion and Acute Pancreatitis in a Child.","authors":"Tal Dror, Virginia Donovan, Naomi Strubel, Sucharita Bhaumik","doi":"10.1155/2021/6610666","DOIUrl":"https://doi.org/10.1155/2021/6610666","url":null,"abstract":"Acute pancreatitis in children is usually due to infection, trauma, or anatomical abnormalities and is rarely due to obstruction from malignancy. Sporadic Burkitt lymphoma (BL) is an aggressive non-Hodgkin B-cell lymphoma that usually involves the bowel or pelvis, with isolated cases presenting as acute pancreatitis. We report a case of BL in a 12-year-old male presenting as acute pancreatitis with obstructive jaundice and a right middle cranial fossa mass invading the sphenoid bone. The common bile duct in this case was dilated to 21 mm in diameter on abdominal ultrasound and to 26 mm on magnetic resonance cholangiopancreatography (MRCP), significantly greater than any value reported in the literature for BL. Given the rapidly progressing nature of BL, we emphasize the importance of recognizing heterogeneous presentations of this disease to improve patient survival. We also conclude that it is important to consider malignancy in a child with acute pancreatitis, particularly in the presence of obstructive jaundice or multisystem involvement. Other Presentations. This case report has no prior publications apart from the abstract being accepted to the 2020 SIOP (International Society of Pediatric Oncology) meeting and 2020 ASPHO conference (canceled due to the COVID-19 pandemic) and subsequently published as an abstract only in Pediatric Blood and Cancer. We have also presented the abstract as a poster presentation at our institution's (NYU Langone Hospital-Long Island, previously known as NYU Winthrop) annual research day conference in 2020.","PeriodicalId":9636,"journal":{"name":"Case Reports in Oncological Medicine","volume":"2021 ","pages":"6610666"},"PeriodicalIF":0.9,"publicationDate":"2021-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457982/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39475408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pancreatic Neuroendocrine Tumor with Benign Serous Cystadenoma: A Rare Entity. 胰腺神经内分泌肿瘤合并良性浆液性囊腺瘤:罕见病例。

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Case Reports in Oncological Medicine Pub Date : 2021-08-04 eCollection Date: 2021-01-01 DOI: 10.1155/2021/9979998

Randhir Sagar Yadav, Ashik Pokharel, Shumneva Shrestha, Ashbita Pokharel, Deepshikha Gaire, Sumita Pradhan, Prasan Bir Singh Kansakar

{"title":"Pancreatic Neuroendocrine Tumor with Benign Serous Cystadenoma: A Rare Entity.","authors":"Randhir Sagar Yadav, Ashik Pokharel, Shumneva Shrestha, Ashbita Pokharel, Deepshikha Gaire, Sumita Pradhan, Prasan Bir Singh Kansakar","doi":"10.1155/2021/9979998","DOIUrl":"https://doi.org/10.1155/2021/9979998","url":null,"abstract":"Mixed serous-neuroendocrine neoplasm constitutes pancreatic serous cystic neoplasms and pancreatic neuroendocrine tumor, two tumor components with different underlying pathologies. The differentiation of these tumors is important as the management and prognosis depend on the pancreatic neuroendocrine tumor component. We report a case of mixed serous-neuroendocrine neoplasm in a 47-year-old female who presented with epigastric pain abdomen for two years. Imaging studies, tumor markers, thorough systemic evaluation, surgical resection, histopathological examination, and timely follow-up constituted our management approach. A 4 cm × 4 cm mass in the distal pancreas with multiple cysts in the pancreatic parenchyma containing serous fluid on distal pancreatectomy and splenectomy was found. The histopathological examination revealed combined benign serous cystadenoma and neuroendocrine tumor. She did not have any recurrence or metastasis by four years of follow-up.","PeriodicalId":9636,"journal":{"name":"Case Reports in Oncological Medicine","volume":"2021 ","pages":"9979998"},"PeriodicalIF":0.9,"publicationDate":"2021-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360748/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39313529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Metastatic Lesion of the Tibia from Renal Cell Carcinoma. 肾细胞癌引起的胫骨转移灶。

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Case Reports in Oncological Medicine Pub Date : 2021-07-30 eCollection Date: 2021-01-01 DOI: 10.1155/2021/2428820

Piotr Młodożeniec, Krzysztof Balawender, Mateusz Zasadny

{"title":"Metastatic Lesion of the Tibia from Renal Cell Carcinoma.","authors":"Piotr Młodożeniec, Krzysztof Balawender, Mateusz Zasadny","doi":"10.1155/2021/2428820","DOIUrl":"https://doi.org/10.1155/2021/2428820","url":null,"abstract":"Introduction: Renal cell carcinoma is responsible for 3% of all cancers, with the highest incidence occurring in Western countries. Additionally, in patients with osseous metastasis, only 3% occur within the tibia. Rarely, a patient presents with a primary complaint of lower limb pain in advanced metastatic renal cell carcinoma. Case Presentation. The patient arrived at the emergency department with a primary complaint of left ankle pain. Ankle X-rays demonstrated a lytic lesion involving the medial malleolus with possible metastatic disease. CT scan confirmed a tumor within the right kidney. The patient was treated with a laparoscopic radical nephrectomy with histopathologic confirmation of clear cell renal cell carcinoma. Biopsy was then performed of the tibial lesion, confirming metastatic clear cell renal cell carcinoma. The tibial lesion was treated with local radiotherapy, and because of the progression of the tibia lesion, a decision was made to amputate the leg. Additionally, the patient was enrolled to sunitinib treatment and was disease free at one year of follow-up. 13 months after diagnosis of cancer, she was suffering a major stroke of the brain that caused her to die.Conclusion: The treatment of patients with osseous metastases of renal cell cancer depends on the number of metastases, location of metastases, and overall health of the patient. We performed an overview of available literature and provided a summary regarding the use of cytoreductive nephrectomy, local therapy, target therapy, and bone-targeting agents in the treatment of metastatic renal cell cancer.","PeriodicalId":9636,"journal":{"name":"Case Reports in Oncological Medicine","volume":"2021 ","pages":"2428820"},"PeriodicalIF":0.9,"publicationDate":"2021-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8349284/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39296362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Case of Retroperitoneal Synovial Sarcoma in Pregnancy Treated with Antepartum Doxorubicin plus Ifosfamide Chemotherapy. 一例妊娠期腹膜后滑膜肉瘤患者接受产前多柔比星加伊佛酰胺化疗的病例

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Case Reports in Oncological Medicine Pub Date : 2021-07-16 eCollection Date: 2021-01-01 DOI: 10.1155/2021/9982171

Bradley H Sipe, Sarah G Običan, Evita Henderson-Jackson, Nicole D Riddle, Rikesh Makanji, Ricardo J Gonzalez, Andrew S Brohl

引用次数: 0

A Rare Presentation of Checkpoint Inhibitor Induced Distal RTA. 检查点抑制剂诱导远端RTA的罕见表现。

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Case Reports in Oncological Medicine Pub Date : 2021-07-15 eCollection Date: 2021-01-01 DOI: 10.1155/2021/7406911

Andrew V Doodnauth, Miriam M Klar, Zohra R Malik, Krunal H Patel, Samy I McFarlane

{"title":"A Rare Presentation of Checkpoint Inhibitor Induced Distal RTA.","authors":"Andrew V Doodnauth, Miriam M Klar, Zohra R Malik, Krunal H Patel, Samy I McFarlane","doi":"10.1155/2021/7406911","DOIUrl":"https://doi.org/10.1155/2021/7406911","url":null,"abstract":"Immune checkpoint inhibitors have opened a new era in treating advanced malignancies, resulting in a rapid increase in utilization, given the remarkable clinical outcomes. The incidence of immune-related adverse events increased due to the immunologic effects of these therapeutic agents. However, immune-related renal adverse events remain low, representing only a small incidence of reported cases. Common renal toxicity described includes acute interstitial nephritis, minimal change disease, and immune complex glomerulonephritis. Renal tubular acidosis has occasionally been reported but is highly uncommon. This report presents a case of a 68-year-old woman with a known history of metastatic melanoma undergoing treatment with ipilimumab+nivolumab, who developed distal renal tubular acidosis requiring stress dose steroids and sodium bicarbonate for treatment. We describe the clinical characteristics, potential mechanisms, and management of this case, highlighting the need among clinicians utilizing immune check inhibitors to be aware of this immune-related disease entity.","PeriodicalId":9636,"journal":{"name":"Case Reports in Oncological Medicine","volume":"2021 ","pages":"7406911"},"PeriodicalIF":0.9,"publicationDate":"2021-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8310435/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39258526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Primary Cecal Squamous Cell Carcinoma: A Case Report of a Rare Tumor with Poor Prognosis. 原发性盲肠鳞状细胞癌:1例罕见的预后不良肿瘤。

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Case Reports in Oncological Medicine Pub Date : 2021-07-14 eCollection Date: 2021-01-01 DOI: 10.1155/2021/6680702

Mohamed Bouzroud, Mustapha Azzakhmam, Aboulfeth El Mehdi, Bouchentouf Sidi Mohammed, El Kaoui Hakim, Oukabli Mohaned, Bounaim Ahmed

引用次数: 1

Management of Intracranial Metastases in EGFR-Mutated NSCLC: A Review of Literature following an Unusual Case Report. egfr突变的非小细胞肺癌颅内转移的治疗:一个罕见病例报告后的文献回顾。

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Case Reports in Oncological Medicine Pub Date : 2021-07-02 eCollection Date: 2021-01-01 DOI: 10.1155/2021/5526809

Víctor Albarrán, Javier Pozas, Juan José Soto, Jorge Esteban, Elena Corral, Yolanda Lage, Pablo Gajate, Pilar Garrido

{"title":"Management of Intracranial Metastases in EGFR-Mutated NSCLC: A Review of Literature following an Unusual Case Report.","authors":"Víctor Albarrán, Javier Pozas, Juan José Soto, Jorge Esteban, Elena Corral, Yolanda Lage, Pablo Gajate, Pilar Garrido","doi":"10.1155/2021/5526809","DOIUrl":"https://doi.org/10.1155/2021/5526809","url":null,"abstract":"The arrival of subsequent generations of tyrosine-kinase inhibitors (TKIs) has significantly broaden the EGFR-mutated lung cancer therapeutic landscape. Results from the FLAURA clinical trial have pushed osimertinib to the first-line treatment for patients with advanced-stage disease, showing outstanding control rates of intracranial metastases, considerably higher than those of the first and second-generation EGFR TKIs. A progressively better knowledge of short and long-term neurocognitive side effects of radiotherapy, as well as the lack of evidence about the benefit of its combination with TKIs, has opened a debate about its indication at diagnosis of intracranial disease, at least before the response to targeted therapy has been evaluated. However, there is a small percentage of primarily resistant cases to osimertinib, mainly due to histologic transformation, acquired EGFR mutations and off-target genetic resistances that lead to a scenery of poor clinical prognosis in which radiotherapy may have a higher relevance for the management of brain metastases. We offer a review of the current recommendations for the management of intracranial metastases in EGFR-mutated NSCLC and the resistance mechanisms to third-generation TKIs, following the report of an unusual clinical case with a rapid progression to osimertinib.","PeriodicalId":9636,"journal":{"name":"Case Reports in Oncological Medicine","volume":"2021 ","pages":"5526809"},"PeriodicalIF":0.9,"publicationDate":"2021-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8272655/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39220372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Angiosarcoma of the Face: A Case Study and Literature Review of Local and Metastatic Angiosarcoma. 面部血管肉瘤：关于局部和转移性血管肉瘤的病例研究和文献综述。

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Case Reports in Oncological Medicine Pub Date : 2021-07-01 eCollection Date: 2021-01-01 DOI: 10.1155/2021/8823585

Hugo Lara-Martinez, Molly Weinberg, Praneeth Baratam, Jeffrey Horn, Kristine Ward, Michael Styler

{"title":"Angiosarcoma of the Face: A Case Study and Literature Review of Local and Metastatic Angiosarcoma.","authors":"Hugo Lara-Martinez, Molly Weinberg, Praneeth Baratam, Jeffrey Horn, Kristine Ward, Michael Styler","doi":"10.1155/2021/8823585","DOIUrl":"10.1155/2021/8823585","url":null,"abstract":"Angiosarcomas are vascular malignancies with a tendency to spread extensively both locally and systemically. We report a case of cutaneous angiosarcoma of the face in a 53-year-old man that was originally misdiagnosed as an abscess. Initially small, the lesion enlarged over a four-to-six-month period and began to bleed. Two shave biopsies were performed that returned a diagnosis of angiosarcoma. The patient underwent radical resection and lymph node dissection, which revealed positive margins and ten of forty-six positive lymph nodes. The patient was treated with paclitaxel and concurrent radiation therapy (RT). Restaging scans showed a new sclerotic lesion of the T10 vertebra, three hepatic lesions, and an adrenal lesion, all concerning for metastasis. Biopsy of one of the hepatic lesions was consistent with metastatic angiosarcoma. In this review, we discuss the presentation of cutaneous angiosarcoma, the importance of early diagnosis, and the treatment options available for metastatic disease that has failed first-line chemotherapy.","PeriodicalId":9636,"journal":{"name":"Case Reports in Oncological Medicine","volume":"2021 ","pages":"8823585"},"PeriodicalIF":0.6,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8270714/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39220373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Breast Cancer Metastasis in a Renal Carcinoma Pulmonary Metastasis: A Rare Example of Tumor-to-Tumor Metastasis. 乳腺癌合并肾癌肺转移:一个罕见的肿瘤间转移病例。

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Case Reports in Oncological Medicine Pub Date : 2021-06-23 eCollection Date: 2021-01-01 DOI: 10.1155/2021/3054232

Áurea Lima, Isa Peixoto, Susana Sarandão, Daniel Melo, Ângelo Rodrigues, Helena Pereira

{"title":"Breast Cancer Metastasis in a Renal Carcinoma Pulmonary Metastasis: A Rare Example of Tumor-to-Tumor Metastasis.","authors":"Áurea Lima, Isa Peixoto, Susana Sarandão, Daniel Melo, Ângelo Rodrigues, Helena Pereira","doi":"10.1155/2021/3054232","DOIUrl":"https://doi.org/10.1155/2021/3054232","url":null,"abstract":"The tumor-to-tumor metastasis phenomenon remains fairly uncommon, with fewer than 100 cases described to present time. Virtually any tumor can be a donor or a recipient neoplasm. Nevertheless, renal carcinomas have been implicated as the most common malignant tumors to harbor metastasis, while lung and breast tumors are the most frequent donors. This article reports an extremely rare case of a breast cancer metastasis in a lung metastasis of clear cell type renal cell carcinoma that met all Campbell and coworkers' tumor-to-tumor metastasis criteria. Additionally, we present the literature case reports of breast cancer metastasis in renal cell carcinomas and try to discuss the mechanisms underlying its occurrence. Since this phenomenon identification will impact the therapeutic strategy and it is not easily detected by image, the anatomopathological study of any and all suspicious lesions is of crucial importance. To the best of our knowledge, this is the first report of a metastasis inside a metastasis.","PeriodicalId":9636,"journal":{"name":"Case Reports in Oncological Medicine","volume":"2021 ","pages":"3054232"},"PeriodicalIF":0.9,"publicationDate":"2021-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8257392/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39183099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2