Case Reports in Dermatological Medicine最新文献

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A Case Report of Improved Palmoplantar Pustulosis following Periodontal Treatment and Possible Association with Diminished Systemic Subclinical Inflammation. 牙周治疗后掌跖脓疱病改善1例,可能与全身亚临床炎症减轻有关。
Case Reports in Dermatological Medicine Pub Date : 2021-10-19 eCollection Date: 2021-01-01 DOI: 10.1155/2021/5548760
Akiko Yamashita, Tomomi Sano, Misaki Iwashita, Fusanori Nishimura
{"title":"A Case Report of Improved Palmoplantar Pustulosis following Periodontal Treatment and Possible Association with Diminished Systemic Subclinical Inflammation.","authors":"Akiko Yamashita,&nbsp;Tomomi Sano,&nbsp;Misaki Iwashita,&nbsp;Fusanori Nishimura","doi":"10.1155/2021/5548760","DOIUrl":"https://doi.org/10.1155/2021/5548760","url":null,"abstract":"<p><p>Palmoplantar pustulosis (PPP) is a recurrent pustular dermatosis located on the palms and soles. Focal infection may exacerbate the symptoms of PPP, but the etiology is not fully clear. A 56-year-old woman with PPP was diagnosed with severe chronic periodontitis. Initial treatment for periodontitis combined with topical application of antibiotics and surgical treatment was performed. In this case, attention was paid to the relevance of systemic inflammation caused by periodontitis with the clinical symptoms of PPP. With periodontal treatment, the symptoms of PPP and periodontitis, high-sensitivity C-reactive protein (hs-CRP) level, and periodontal inflamed surface area (PISA) improved. This case highlights the importance of comprehensive dental examinations, including those for oral infections, such as periodontitis and other unrecognized sources of infection, and dental treatment in the overall management of PPP.</p>","PeriodicalId":9630,"journal":{"name":"Case Reports in Dermatological Medicine","volume":"2021 ","pages":"5548760"},"PeriodicalIF":0.0,"publicationDate":"2021-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548172/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39660569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lymphocutaneous Sporotrichosis Refractory to First-Line Treatment. 淋巴皮肤孢子菌病对一线治疗难治性。
Case Reports in Dermatological Medicine Pub Date : 2021-10-06 eCollection Date: 2021-01-01 DOI: 10.1155/2021/9453701
Walter Belda, Luiz Felipe Domingues Passero, Ana Thereza Stradioto Casolato
{"title":"Lymphocutaneous Sporotrichosis Refractory to First-Line Treatment.","authors":"Walter Belda,&nbsp;Luiz Felipe Domingues Passero,&nbsp;Ana Thereza Stradioto Casolato","doi":"10.1155/2021/9453701","DOIUrl":"https://doi.org/10.1155/2021/9453701","url":null,"abstract":"<p><p>Sporotrichosis is a fungal infection endemic in Latin America and has been attributed to the thermodimorphic fungus of the genus <i>Sporothrix</i>. Transmission to humans occurs during a traumatic injury with soil or organic material; additionally, lesions caused by infected cats play an important role in the epidemiology of the disease. The classic treatment of sporotrichosis is performed with itraconazole or potassium iodide; second-line medications, such as amphotericin B and terbinafine, can alternatively be used in cases of first-line drug failure. In the present study, a patient with lymphocutaneous sporotrichosis in the right upper limb exhibited intolerance to itraconazole and potassium iodide, additionally during the period of use; these drugs did not control skin lesions. In this patient, amphotericin B deoxycholate and its liposomal version were used in this patient; and complete recovery of the lesions was observed.</p>","PeriodicalId":9630,"journal":{"name":"Case Reports in Dermatological Medicine","volume":"2021 ","pages":"9453701"},"PeriodicalIF":0.0,"publicationDate":"2021-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514908/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39526324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
A Guttate Psoriasis That Tends to Spare Three Tattoos: A Macrophage Liaison. 一种牛皮癣倾向于保留三个纹身:巨噬细胞的联系。
Case Reports in Dermatological Medicine Pub Date : 2021-09-11 eCollection Date: 2021-01-01 DOI: 10.1155/2021/9448636
Panagiota Spyridonos, Vasiliki Zampeli, Sophia-Nefeli Rapti, Ioannis D Bassukas
{"title":"A Guttate Psoriasis That Tends to Spare Three Tattoos: A Macrophage Liaison.","authors":"Panagiota Spyridonos,&nbsp;Vasiliki Zampeli,&nbsp;Sophia-Nefeli Rapti,&nbsp;Ioannis D Bassukas","doi":"10.1155/2021/9448636","DOIUrl":"https://doi.org/10.1155/2021/9448636","url":null,"abstract":"Induction of new psoriasis sites was reported in only a small amount of psoriasis patients undergoing tattooing, despite the intuitive belief that tattoo trauma might awaken the disease due to the isomorphic phenomenon of Koebner. In this case report, we discuss a patient who presented with a remarkable sparing of his three tattoo sites during a guttate psoriasis flare-up that was unrelated to tattooing. The spatial concordance of tattoo and psoriasis lesions was analyzed on clinical pictures of tattoo sites taken during the psoriasis episode. For the quantification of the spatial distribution of the psoriasis lesions, Voronoi diagrams were generated, and coefficients of variation and the two-sample t-test were employed to compare the distributions of Voronoi patch sizes in different settings. Compared to skin areas without tattoos, a tattoo introduced a higher variation in the sizes of the Voronoi patches centered around psoriasis lesions. Based on our findings, we would like to discuss the possible role of macrophages as the key cellular link in the complex pathophysiologic relationship between tattooing/tattoo and psoriasis. Taking into account the relationship of autophagy and psoriasis lesions, we propose the hypothesis that tattoos represent a “psoriasis-hostile” tissue environment pertained by a population of LAP active M2-polarized macrophages. Further clinical studies of the relationship of psoriasis lesions to the tattooed skin are needed and may provide important insights into the role of macrophages in the pathogenesis of psoriasis.","PeriodicalId":9630,"journal":{"name":"Case Reports in Dermatological Medicine","volume":"2021 ","pages":"9448636"},"PeriodicalIF":0.0,"publicationDate":"2021-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8452437/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39440281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Brooke-Spiegler Syndrome: Familial Cylindromatosis, a Rare Variant of a Rare Familial Syndrome. 布鲁克-斯皮格勒综合征:家族性圆筒状病,一种罕见家族综合征的罕见变体。
Case Reports in Dermatological Medicine Pub Date : 2021-06-23 eCollection Date: 2021-01-01 DOI: 10.1155/2021/7118260
Harsh Patel, William Naber, Austin Cusick, Craig Oser
{"title":"Brooke-Spiegler Syndrome: Familial Cylindromatosis, a Rare Variant of a Rare Familial Syndrome.","authors":"Harsh Patel,&nbsp;William Naber,&nbsp;Austin Cusick,&nbsp;Craig Oser","doi":"10.1155/2021/7118260","DOIUrl":"https://doi.org/10.1155/2021/7118260","url":null,"abstract":"<p><p>Brooke-Spiegler Syndrome (BSS) is a rare autosomal dominant familial disorder resulting in dermatologic neoplasms of copious nodular appendages. Here, we report a case of Familial Cylindromatosis (FC), a subtype of BSS, in a patient with the largest cylindroma of 7.4 × 5.6 × 3.8 cm on the scalp. The patient had undiagnosed cylindromas growing for 36 years at presentation; however, he did not seek out healthcare evaluation. Excision and pathologic investigation of three large masses from different body sites determined a shared phenotype of cylindromas. Subsequent evaluation of the patient's son separately, after primary patient excision, confirmed cylindroma development as well. The pathologic evidence of cylindromas in the patient with a new history of family incidence confirmed the diagnosis of the FC variant of BSS.</p>","PeriodicalId":9630,"journal":{"name":"Case Reports in Dermatological Medicine","volume":"2021 ","pages":"7118260"},"PeriodicalIF":0.0,"publicationDate":"2021-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245218/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39180731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Erythema Multiforme Induced by a "Milker's Nodule" Pseudocowpox Infection: A Case Report and Review of Literature. “牛奶结节”性假牛痘感染致多形性红斑1例并文献复习。
Case Reports in Dermatological Medicine Pub Date : 2021-06-17 eCollection Date: 2021-01-01 DOI: 10.1155/2021/5584773
Kyle Wu, Sara de Menezes, Aaron Robinson
{"title":"Erythema Multiforme Induced by a \"Milker's Nodule\" Pseudocowpox Infection: A Case Report and Review of Literature.","authors":"Kyle Wu,&nbsp;Sara de Menezes,&nbsp;Aaron Robinson","doi":"10.1155/2021/5584773","DOIUrl":"https://doi.org/10.1155/2021/5584773","url":null,"abstract":"<p><p>Milker's nodule is caused by the pseudocowpox virus following inoculation from infected cattle. We report the case of erythema multiforme induced by pseudocowpox infection in an 18-year-old female from regional Australia. While erythema multiforme has been described as a complication of orf, it is rare as a sequela of pseudocowpox infection. Greater clinical knowledge of this disease and potential complications aid in guiding appropriate management of this phenomenon.</p>","PeriodicalId":9630,"journal":{"name":"Case Reports in Dermatological Medicine","volume":"2021 ","pages":"5584773"},"PeriodicalIF":0.0,"publicationDate":"2021-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233095/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39166301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Oral Isotretinoin Therapy in Recalcitrant Molluscum Contagiosum in an Immunocompromised Patient. 口服异维甲酸治疗免疫功能低下患者的顽固性传染性软疣。
Case Reports in Dermatological Medicine Pub Date : 2021-06-14 eCollection Date: 2021-01-01 DOI: 10.1155/2021/5529382
Vikash Paudel, Deepa Chudal
{"title":"Oral Isotretinoin Therapy in Recalcitrant Molluscum Contagiosum in an Immunocompromised Patient.","authors":"Vikash Paudel,&nbsp;Deepa Chudal","doi":"10.1155/2021/5529382","DOIUrl":"https://doi.org/10.1155/2021/5529382","url":null,"abstract":"<p><p>Molluscum contagiosum is a viral infection caused by the Poxvirus characterized by multiple umbilicated papules. It is common in children and can be present at any body site. Severe molluscum is common in immunocompromised patients. We report a 20-year-old HIV-positive individual with widespread molluscum contagiosum, recalcitrant to topical therapy, under antiretroviral therapy, who was treated with oral isotretinoin and had a dramatic outcome. Although studies are needed to confirm the effectiveness of oral isotretinoin therapy in molluscum contagiosum, its easy availability, cost, and excellent safety profile appear to offer a promising therapeutic option.</p>","PeriodicalId":9630,"journal":{"name":"Case Reports in Dermatological Medicine","volume":"2021 ","pages":"5529382"},"PeriodicalIF":0.0,"publicationDate":"2021-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8216825/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39162942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
New-Onset Bullous Pemphigoid in a COVID-19 Patient. 新发大疱性类天疱疮1例。
Case Reports in Dermatological Medicine Pub Date : 2021-06-07 eCollection Date: 2021-01-01 DOI: 10.1155/2021/5575111
Natalie Olson, David Eckhardt, Angela Delano
{"title":"New-Onset Bullous Pemphigoid in a COVID-19 Patient.","authors":"Natalie Olson,&nbsp;David Eckhardt,&nbsp;Angela Delano","doi":"10.1155/2021/5575111","DOIUrl":"https://doi.org/10.1155/2021/5575111","url":null,"abstract":"<p><p>This manuscript presents a report of bullous pemphigoid rash associated with COVID-19 for the first time. The objective of this manuscript is to present a unique dermatological case in the setting of a COVID-19-positive infection to further recognize the virus symptomatology. A 37-year-old female with a past medical history of class III obesity, type II diabetes mellitus, and hypertension presented to the emergency department in September 2020 with inpatient and outpatient follow-up through to November 2020. The patient denied any personal or family history of skin disorders. The patient tested positive for COVID-19 prior to hospitalization and presented to the hospital with severe, persistent, pruritic rash meeting dermatopathological, serologic, and clinical criteria for bullous pemphigoid diagnosis. Histopathology H&E punch biopsy from her left flexor wrist demonstrated epidermal keratinocyte necrosis, subepidermal vesiculation with eosinophils, gossamer stranding of the papillary dermis, and subepidermal edema. Direct immunofluorescence punch biopsy from her left flexor wrist demonstrated strong linear IgG staining at the dermoepidermal junction, with weaker and focal linear C3 staining. Antigen-specific serology was consistent with bullous pemphigoid. There was no previously reported cutaneous association of COVID-19 infection with bullous pemphigoid making this case an important addition to the body of evidence helping to identify bullous pemphigoid in the setting of viral infection.</p>","PeriodicalId":9630,"journal":{"name":"Case Reports in Dermatological Medicine","volume":"2021 ","pages":"5575111"},"PeriodicalIF":0.0,"publicationDate":"2021-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8187076/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39139899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 20
Acquired Acrodermatitis Enteropathica in a 28-Year-Old Male with Type 1 Diabetes. 28岁男性1型糖尿病后天性肢端皮炎肠病。
Case Reports in Dermatological Medicine Pub Date : 2021-05-25 eCollection Date: 2021-01-01 DOI: 10.1155/2021/5572583
Owen Ngalamika, Wencilaus M P Selvaraj, Fatima K Yikona, Chibamba Mumba
{"title":"Acquired Acrodermatitis Enteropathica in a 28-Year-Old Male with Type 1 Diabetes.","authors":"Owen Ngalamika,&nbsp;Wencilaus M P Selvaraj,&nbsp;Fatima K Yikona,&nbsp;Chibamba Mumba","doi":"10.1155/2021/5572583","DOIUrl":"https://doi.org/10.1155/2021/5572583","url":null,"abstract":"<p><p>Acrodermatitis enteropathica (AE) is a rare disorder arising from inherited or acquired zinc deficiency. It is mainly characterized by acral dermatitis, periorificial dermatitis, alopecia, and gastrointestinal symptoms in the form of diarrhea. There are many complications of AE including local and systemic infections that may develop as a result of untreated AE. In addition, due to the role of zinc in glucose metabolism, chronic zinc deficiency may pose a challenge in the control of blood glucose levels in diabetics. We report the case of a 28-year-old male with type 1 diabetes who presented with signs and symptoms of AE.</p>","PeriodicalId":9630,"journal":{"name":"Case Reports in Dermatological Medicine","volume":"2021 ","pages":"5572583"},"PeriodicalIF":0.0,"publicationDate":"2021-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8169277/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39089185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Use of Reflectance Confocal Microscopy for Hidrocystomas: An Emerging, Cost-Effective, and Powerful Tool. 使用反射共聚焦显微镜对汗液囊肿:一个新兴的,具有成本效益的,强大的工具。
Case Reports in Dermatological Medicine Pub Date : 2021-04-09 eCollection Date: 2021-01-01 DOI: 10.1155/2021/5543803
Amanda Walker, Vikram Nath Sahni, Dev Ram Sahni, Julia Curtis
{"title":"Use of Reflectance Confocal Microscopy for Hidrocystomas: An Emerging, Cost-Effective, and Powerful Tool.","authors":"Amanda Walker,&nbsp;Vikram Nath Sahni,&nbsp;Dev Ram Sahni,&nbsp;Julia Curtis","doi":"10.1155/2021/5543803","DOIUrl":"https://doi.org/10.1155/2021/5543803","url":null,"abstract":"<p><p>Reflectance confocal microscopy (RCM) is an emerging and noninvasive imaging tool in dermatological practice. Benefits of this modality include differentiation between benign and malignant skin lesions, prevention of unnecessary biopsies, and cost effectiveness. However, RCM findings for benign lesions are rarely reported in the literature. We describe a case of reflectance confocal microscopy findings of a hidrocystoma and review potential applications of this imaging technique in everyday clinical practice.</p>","PeriodicalId":9630,"journal":{"name":"Case Reports in Dermatological Medicine","volume":"2021 ","pages":"5543803"},"PeriodicalIF":0.0,"publicationDate":"2021-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8052164/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38907843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Halo Nevi Are Not Trivial: About 2 Young Patients of Regressed Primary Melanoma That Simulates Halo Nevi. 光环痣不是微不足道的:关于两个年轻的退化原发性黑色素瘤患者,模拟光环痣。
Case Reports in Dermatological Medicine Pub Date : 2021-03-22 eCollection Date: 2021-01-01 DOI: 10.1155/2021/6672528
S De Schrijver, I Theate, O Vanhooteghem
{"title":"Halo Nevi Are Not Trivial: About 2 Young Patients of Regressed Primary Melanoma That Simulates Halo Nevi.","authors":"S De Schrijver,&nbsp;I Theate,&nbsp;O Vanhooteghem","doi":"10.1155/2021/6672528","DOIUrl":"https://doi.org/10.1155/2021/6672528","url":null,"abstract":"<p><strong>Background: </strong>Halo nevi are often considered benign, and the possibility of malignancy is not always clear to practitioners. We present two case reports suggesting that a halo nevus appearance can be seen in melanoma, even in young adults. A literature search for halo nevi revealing melanoma shows that this is a very rare condition. <i>Case presentation</i>. This report of two young patients indicates the importance of obtaining a detailed history to detect warning signs such as itching, pain, spontaneous bleeding, and previous alterations according to the patient, including a previously totally black colour in an already fully regressed melanoma.</p><p><strong>Conclusions: </strong>The risk of a halo nevus being malignant is higher if there is only one unique halo nevus and no personal or familial history of vitiligo. We postulate that a regressing atypical nevus or a regressing melanoma may be induced by an immunologic reaction as halo nevus type of clinical picture.</p>","PeriodicalId":9630,"journal":{"name":"Case Reports in Dermatological Medicine","volume":"2021 ","pages":"6672528"},"PeriodicalIF":0.0,"publicationDate":"2021-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009706/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38878263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
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