A Rare Cutaneous Manifestation: Leukocytoclastic Vasculitis after Pfizer-BioNTech COVID-19 Vaccination.

Q3 Medicine
Yaritza Serrano Gomez, Brittney Grella, Hongbei Wang
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引用次数: 1

Abstract

There is growing evidence that vaccines against SARS-CoV-2 can cause various skin reactions, many of which have autoimmune origins. These specific vaccine-induced autoimmune conditions with cutaneous manifestations include lupus erythematosus, bullous pemphigoid, vitiligo, alopecia areata, and leukocytoclastic vasculitis (LCV). In particular, LCV, which is also called hypersensitivity vasculitis, is an inflammation of small blood vessels. We present a case of an 81-year-old male evaluated in the emergency department for a bilateral purpuric non-blanching rash that appeared ten days after receiving the Pfizer-BioNTech booster vaccine against SARS-CoV-2. Results of a skin biopsy indicated LCV, and the rash completely resolved three weeks after clinical presentation.

Abstract Image

Abstract Image

一种罕见的皮肤表现:辉瑞- biontech COVID-19疫苗接种后的白细胞分裂性血管炎。
越来越多的证据表明,针对SARS-CoV-2的疫苗可引起各种皮肤反应,其中许多反应源于自身免疫。这些具有皮肤表现的特异性疫苗诱导的自身免疫性疾病包括红斑狼疮、大疱性类天疱疮、白癜风、斑秃和白细胞破壁性血管炎(LCV)。特别是LCV,也称为超敏性血管炎,是一种小血管的炎症。我们报告了一例81岁男性患者,在接受了针对SARS-CoV-2的辉瑞- biontech加强疫苗10天后出现双侧紫癜性非漂白皮疹,在急诊科接受了评估。皮肤活检结果提示LCV,皮疹在临床表现后三周完全消退。
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来源期刊
CiteScore
1.50
自引率
0.00%
发文量
24
审稿时长
15 weeks
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