Case Reports in Medicine最新文献

{"title":"Case Report of Unilateral Short-Root Abnormality Disease of Multiple Roots.","authors":"Zhihao Tang, Xiaodan Fang, Yuxin Yang, Xin Liu","doi":"10.1155/carm/1295291","DOIUrl":"10.1155/carm/1295291","url":null,"abstract":"<p><p>Short root anomaly (SRA) is a rare developmental disturbance characterized by markedly shortened and blunted roots with a root-to-crown ratio below 1, while the crown morphology and periodontal structures remain unaffected. Most reported cases show bilateral symmetric involvement of maxillary anterior teeth. This paper presents a unique case of unilateral multiple SRA affecting mandibular canine, premolars, and molars combined with facial asymmetry in a 22-year-old male patient. No active treatment was performed except standardized oral hygiene instructions and regular follow-up. This case expands the phenotypic spectrum of SRA and highlights the importance of comprehensive differential diagnosis.</p>","PeriodicalId":9627,"journal":{"name":"Case Reports in Medicine","volume":"2026 ","pages":"1295291"},"PeriodicalIF":1.0,"publicationDate":"2026-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13519959/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148839206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synchronous Coexistence of JAK2 V617F-Positive Essential Thrombocythemia and IgG Kappa Multiple Myeloma in an Octogenarian Patient: A Case Report.","authors":"Marcel Ribero-Vargas, Fabián Ahumada-Córdoba, Nhora María Silva-Pérez, Daniel Ribero-Vargas","doi":"10.1155/carm/8986847","DOIUrl":"10.1155/carm/8986847","url":null,"abstract":"<p><p>The synchronous coexistence of JAK2 V617F-positive essential thrombocythemia (ET) and IgG kappa multiple myeloma (MM) is exceptionally rare, with fewer than 10 synchronous cases reported in the literature. The present case is unique in that MM was discovered incidentally during systematic bone marrow evaluation for isolated thrombocytosis in an octogenarian with significant comorbidities, requiring the concurrent management of two independent clonal hematological neoplasms. An 81-year-old woman with prior hypertension and cerebrovascular disease was referred for persistent thrombocytosis exceeding 1,000,000 platelets/μL. Systematic bone marrow evaluation led to the incidental identification of a monoclonal kappa plasma cell population, prompting full myeloma workup. JAK2 V617F-positive high-risk ET and IgG kappa MM (ISS Stage II) were diagnosed synchronously. Acquired von Willebrand syndrome was excluded prior to any anticoagulation decision. Treatment included hydroxyurea-subsequently switched to anagrelide due to a national drug supply shortage-for ET cytoreduction, and a bortezomib-dexamethasone-lenalidomide (VRD) regimen for MM. An IMWG partial response was achieved after three cycles, with adequate platelet control at 8 months of follow-up. This case underscores the importance of systematic bone marrow evaluation in myeloproliferative neoplasms, as it may unmask concurrent plasma cell dyscrasias. Several pathophysiological mechanisms-including IL-6-mediated microenvironmental activation, BAFF-driven B-cell proliferation, and a shared inflammatory niche-have been proposed in the literature to explain this co-occurrence; however, these were not directly evaluated in this patient. The regimen chosen was guided by clinical complexity and resource constraints rather than current preferred first-line guidelines, which favor daratumumab-based combinations for transplant-ineligible patients. Early identification of coexisting clonal neoplasms substantially impacts prognosis and therapeutic decision-making.</p>","PeriodicalId":9627,"journal":{"name":"Case Reports in Medicine","volume":"2026 ","pages":"8986847"},"PeriodicalIF":1.0,"publicationDate":"2026-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13507830/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148825269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Undiagnosed Pheochromocytoma During Pregnancy Presenting Initially With Neurological Manifestations: A Case Report.","authors":"Tahereh Babaei, Seyed Ahmad Hosseini, Hadi Majidi, Somayeh Sheidaei, Nazanin Nosrati, Azadeh Nazari Tileh Noei, Kosar Babaei","doi":"10.1155/carm/5345705","DOIUrl":"10.1155/carm/5345705","url":null,"abstract":"<p><p>A 50-year-old pregnant woman (G3Ab2) who had her fourth IVF procedure during the first trimester of her pregnancy is described in this article as having a rare incidence of acute paraplegia. The patient's early symptoms included headache, sudden lower limb weakness, urine retention, back discomfort, and uncontrolled hypertension. The patient had a history of infertility, thyroidectomy, hypertension, and repeated spontaneous abortions. After transverse myelitis was confirmed by spinal MRI, methylprednisolone pulse therapy and plasmapheresis were started as treatments. Subsequent analysis of CSF fluid showed purulent meningitis. An unexpected abortion occurred 48 h later. She had fast hypotension, confusion, and a hemoglobin drop from 10 to 5 g/dL over 72 h. A tumor in the left adrenal gland and a sizable, active hematoma in the right adrenal gland were discovered by abdominal imaging. After a right adrenalectomy and mass draining were done in an emergency, the pheochromocytoma was finally diagnosed. The patient was briefly stabilized postsurgery but ultimately succumbed. This case is one of the limited instances documented in the scientific literature, when the emergence of neurological symptoms from transverse myelitis serves as the initial manifestation of pheochromocytoma, in conjunction with high-risk pregnancy, IVF, and an aggressive clinical trajectory. Consequently, in instances of unstable or early hypertension in pregnancy with neurological symptoms, differential diagnosis should include neuroendocrine tumors such as pheochromocytoma.</p>","PeriodicalId":9627,"journal":{"name":"Case Reports in Medicine","volume":"2026 ","pages":"5345705"},"PeriodicalIF":1.0,"publicationDate":"2026-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13501165/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148811983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Case of Primary Ciliary Dyskinesia Caused by <i>CFTR</i> Gene and <i>SFTPC</i> Gene Variants.","authors":"Xinhui Yuan, Dan Shao, Yumei Li, Jizu Ling, Yigu Gong","doi":"10.1155/carm/2903077","DOIUrl":"10.1155/carm/2903077","url":null,"abstract":"<p><strong>Introduction: </strong>This study retrospectively analyzed the clinical data of a female child with primary ciliary dyskinesia (PCD) caused by variants in the CFTR (NM_000492.3) and SFTPC (NM_003018.3). All variant descriptions in this report follow the HGVS standardized nomenclature guidelines. These two variants are considered to be potentially associated with pediatric PCD.</p><p><strong>Case presentation: </strong>A 13-year-old Chinese female patient with a history of recurrent respiratory infections was admitted due to intermittent cough and sputum production for one month, exacerbated by fever for five days. Chest CT revealed a lung infection and bronchiectasis. Transmission electron microscopy of ciliary biopsy identified structural abnormalities in bronchial mucosa cilia, including aberrant microtubule arrangements (8 + 2, 9 + 1, and 7 + 2 patterns), and disorganized peripheral microtubules. The whole-exome sequencing (WES) identified a heterozygous variant c.374T > C (p.Ile125Thr) in CFTR (NM_000492.3) and a heterozygous variant c.115G > T (p.Val39Leu) in SFTPC (NM_003018.3), with all nomenclature complying with HGVS recommendations. A comprehensive diagnosis of PCD was confirmed. The patient improved after anti-infective and symptomatic therapy and was discharged.</p><p><strong>Conclusion: </strong>Variants in the CFTR and SFTPC genes may be associated with PCD in children. This case highlights the importance of early genetic variant testing and ciliary ultrastructural analysis (e.g., transmission electron microscopy) in children with recurrent respiratory tract infections, bronchiectasis, or chronic sinusitis, thereby facilitating timely diagnosis and clinical intervention.</p>","PeriodicalId":9627,"journal":{"name":"Case Reports in Medicine","volume":"2026 ","pages":"2903077"},"PeriodicalIF":1.0,"publicationDate":"2026-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13504242/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148817516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Renal Cell Carcinoma With Hemangioblastoma-Like Features, Fibromyomatous Stroma, and TSC1 Mutation.","authors":"Shiyun Yao, Jinghui Huang, Mingfa Wang, Chunji Quan","doi":"10.1155/carm/3548941","DOIUrl":"10.1155/carm/3548941","url":null,"abstract":"<p><p>Renal cell carcinoma (RCC) with fibromyomatous stroma (RCC-FMS) was classified as an \"emerging/provisional\" entity in the 2016 WHO classification of tumors, specifically categorized as RCC with (vascular) fibromyomatous stroma. However, it was not included in the 2022 WHO classification. Renal cell carcinoma with hemangioblastoma (RCC-HB)-like features has also been reported infrequently in recent years. RCC-HB-like features and fibromyomatous stroma is quite rare, with only two reports in the literature. This report describes a rare tumor of RCC-HB-like features and fibromyomatous stroma associated with TSC1 mutations. A female patient was incidentally discovered a right renal mass during a routine physical examination conducted 2 weeks prior. Histology revealed that the tumor consisted of three distinct components: clear cell papillary renal cell tumor (CCPRCT)-like areas, fibromyomatous stroma, and HB-like areas. Immunohistochemical staining showed that the CCPRCT-like components exhibited basolateral, cup-shaped CAIX staining and were diffusely positive for AE1/AE3, CK7, and PAX-8, partially positive for AMACR/P504S, and weakly positive for CD10. The fibromyomatous stroma was positive for H-caldesmon, desmin, and SMA. In the HB-like components, α-inhibin, ERG, CD34, CAIX, and vimentin were all diffusely positive, CD10 was partially positive, and PAX-8 showed scattered, weak positivity. Whether RCC-HB features and fibromyomatous stroma can be regarded as a distinct subtype of RCC remains to be discussed by accumulation of more cases.</p>","PeriodicalId":9627,"journal":{"name":"Case Reports in Medicine","volume":"2026 ","pages":"3548941"},"PeriodicalIF":1.0,"publicationDate":"2026-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13501119/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148811986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vitamin K Antagonist-Induced Calciphylaxis in a Dialysis Patient With Antiphospholipid Syndrome: A Multidisciplinary Case Report.","authors":"Rafat A A Atawneh, Ahmed Algharib, Rüdiger Möller","doi":"10.1155/carm/8244011","DOIUrl":"10.1155/carm/8244011","url":null,"abstract":"<p><p>Calciphylaxis, or calcific uremic arteriolopathy (CUA), is a rare, life-threatening syndrome characterized by microvascular calcification and cutaneous necrosis, predominantly affecting patients with end-stage renal disease (ESRD) on maintenance dialysis, particularly those exposed to vitamin K antagonists (VKAs). We report the complex clinical course of a 35-year-old female patient with chronic kidney failure and triple-positive antiphospholipid syndrome (APS) who presented with severe, painful bilateral thigh ulcerations. The patient had been receiving phenprocoumon for 2 years. Given her high-risk profile for thrombosis, managing cutaneous necrosis while maintaining necessary anticoagulation presented a profound clinical dilemma. Histopathological evaluation confirmed the diagnosis of calciphylaxis. VKA therapy was immediately discontinued and replaced with renal-adjusted apixaban to manage her underlying APS as an individualized rescue strategy. A multimodal, sequential wound care regimen was initiated, incorporating serial surgical debridements, negative pressure wound therapy (NPWT), autologous platelet-rich plasma (PRP) infiltration, and acellular fish skin grafting. Following intensive multidisciplinary intervention involving vascular surgery, nephrology, and dermatology, the progression of the disease was successfully halted. Significant wound contraction, stable granulation, and complete epithelialization were achieved without systemic complications. This case underscores that short-term VKA exposure can act as a critical trigger for calciphylaxis in patients with multifactorial risk profiles and demonstrates that a tailored transition to novel oral anticoagulants combined with advanced wound therapies can achieve favorable outcomes in highly complex, refractory scenarios.</p>","PeriodicalId":9627,"journal":{"name":"Case Reports in Medicine","volume":"2026 ","pages":"8244011"},"PeriodicalIF":1.0,"publicationDate":"2026-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13478789/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148788734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Case Report: A Rare Case of Thrombocytopenia in Pregnancy, due to Suspected Acquired Amegakaryocytic Thrombocytopenia.","authors":"Nuong Truong, Layan Alrahmani, Kristen Krum, Kevin Barton, Phillip J DeChirstopher, Ameet Kini, Samreen Fathima, Namisha Dhillon, Nicole Sprawka, Joana Lopes Perdigao, Srichandhana Rajamouli, Stephanie Rodriguez, Kalee Ahlin, Ann Lal","doi":"10.1155/carm/6644995","DOIUrl":"10.1155/carm/6644995","url":null,"abstract":"<p><p>Acquired amegakaryocytic thrombocytopenia (AAT) in pregnancy is rare, with only one case report previously published on this condition. Our case is a 33-year-old G3P2002 female with severe thrombocytopenia, suspected to be due to AAT, who was managed with eltrombopag, prednisone, and cyclosporine A. The patient delivered at 32 weeks due to preeclampsia with severe features. She had an uncomplicated postpartum course, and the neonate did not have thrombocytopenia. With a multidisciplinary approach to care, our management approach to a patient with severe thrombocytopenia in pregnancy resulted in an uncomplicated delivery, without maternal or fetal complications.</p>","PeriodicalId":9627,"journal":{"name":"Case Reports in Medicine","volume":"2026 ","pages":"6644995"},"PeriodicalIF":1.0,"publicationDate":"2026-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13478910/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148788806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute Inflammatory Demyelinating Polyradiculoneuropathy Presenting With Multiple Cranial Nerve Palsies and Total Ophthalmoplegia: The Importance of Accurate Diagnosis and Timely Immunotherapy.","authors":"Niswah Silmi Fatimah, Abdulloh Machin","doi":"10.1155/carm/3658834","DOIUrl":"10.1155/carm/3658834","url":null,"abstract":"<p><p>Guillain-Barré syndrome (GBS) is an immune-mediated disorder of the peripheral nervous system characterized by progressive weakness and often triggered by infections. GBS has an estimated mortality rate of approximately 5%, with a worldwide incidence of 0.81-1.91 cases per 1,00,000 person-years. This case reported a 23-year-old man presented with progressive weakness in all four extremities. An initial neurological examination revealed bilateral total ophthalmoplegia, ptosis on both eyes, bilateral facial palsy lower motor neuron (LMN) type, dysarthria, dysphagia, flaccid tetra-paresis, gloves, and stocking paresthesia. Lumbar puncture showed cytoalbumin dissociation. Nerve conduction studies showed a demyelinating sensorimotor polyradiculoneuropathy lesion. The patient received intravenous immunoglobulin (IVIG) treatment 0.4 g/kg/day for 5 days, physical rehabilitation therapy, nutritional support, multidisciplinary care involving anesthesiology and intensive care teams, and other symptomatic treatments. At five-month follow-up, the patient demonstrated complete recovery. GBS typically presents as an acute ascending sensorimotor neuropathy; however, atypical presentations may occur. Extensive cranial nerve involvement-including complete ophthalmoplegia, bilateral facial palsy, and bulbar dysfunction-in AIDP is uncommon and may mimic other GBS spectrum disorders. Early recognition, prompt immunotherapy, and careful electrophysiological evaluation are essential for optimizing patient outcomes. Because electrodiagnostic classification of GBS may evolve over time, serial nerve conduction studies should be considered whenever feasible to improve subtype classification and diagnostic confidence.</p>","PeriodicalId":9627,"journal":{"name":"Case Reports in Medicine","volume":"2026 ","pages":"3658834"},"PeriodicalIF":1.0,"publicationDate":"2026-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13470610/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148759139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electroclinical Dissociation in Generalized Epilepsy: A Video-EEG Case From Sub-Saharan Africa.","authors":"Yihealem Yabebal Ayele","doi":"10.1155/carm/5593355","DOIUrl":"10.1155/carm/5593355","url":null,"abstract":"<p><strong>Introduction: </strong>Functional neurological symptoms, specifically functional dissociative seizures (FDS), frequently coexist with epilepsy and pose severe diagnostic challenges, particularly in resource-limited settings where video-electroencephalography (video-EEG) access is scarce. Overreliance on interictal or noncausal epileptiform EEG abnormalities without rigorous electroclinical correlation risks misdiagnosis and hazardous escalation of antiseizure medications (ASMs).</p><p><strong>Case presentation: </strong>We report a 17-year-old male from rural Ethiopia with a 4-year history of genetic generalized epilepsy (GGE) and mild intellectual impairment who presented with persistent, variable left lower limb jerking following a road traffic accident involving the same limb. Video-EEG captured the jerking episodes and demonstrated generalized spike-wave and polyspike-wave discharges (3-4 Hz) that coincided temporally with clinical jerks but lacked electrographic evolution, focal cortical origin, or muscle phase-locking on surface recording. The events occurred exclusively during wakefulness with preserved awareness, no autonomic instability, and no postictal state. Sequential ASM trials (levetiracetam, valproate, clonazepam, and phenobarbital) failed to modulate the jerks. The electroclinical presentation was interpreted as electroclinical dissociation, confirming coexisting generalized epilepsy and FDS. The patient had also undergone posterior fossa decompression for Chiari I malformation 9 days prior, which was excluded as a cause for the motor events based on clinical and radiological stability.</p><p><strong>Conclusion: </strong>Diagnostic evaluation of FDS should rely on a positive \"rule-in\" framework as recommended by international guidelines. Even when epileptiform discharges appear on EEG during clinical events, a lack of physiological congruence between electrographic patterns and semiology confirms electroclinical dissociation.</p>","PeriodicalId":9627,"journal":{"name":"Case Reports in Medicine","volume":"2026 ","pages":"5593355"},"PeriodicalIF":1.0,"publicationDate":"2026-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13463240/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148721393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Collapsing Glomerulopathy in a Patient With Malaria and Multiple Myeloma: A Case Report.","authors":"Moritz Harenberg, Kerstin Amann, Daniel Zickler","doi":"10.1155/carm/9149610","DOIUrl":"10.1155/carm/9149610","url":null,"abstract":"<p><p>Collapsing glomerulopathy is a severe form of focal segmental glomerulosclerosis (FSGS) that can occur as a primary or secondary condition, often in the context of infections such as HIV. Multiple myeloma can cause kidney injury through mechanisms such as cast nephropathy, while malaria-associated kidney injury is most often due to acute tubular necrosis. We present the case of a 47-year-old male of African descent with well-controlled HIV infection who became critically ill with severe AKI requiring intensive care and renal replacement therapy. A blood smear confirmed <i>Plasmodium falciparum</i> infection, and the clinical course was further complicated by a previously undiagnosed multiple myeloma. Given the multiple potential etiologies, a kidney biopsy was performed, which ruled out myeloma-associated kidney injury and revealed collapsing glomerulopathy. The temporal association with the malaria infection, together with the well-controlled HIV status, pointed to malaria-associated collapsing glomerulopathy as the most likely diagnosis. This case highlights the diagnostic challenges of AKI in critically ill patients with overlapping comorbidities and underscores the value of kidney biopsy in guiding the differential diagnosis.</p>","PeriodicalId":9627,"journal":{"name":"Case Reports in Medicine","volume":"2026 ","pages":"9149610"},"PeriodicalIF":1.0,"publicationDate":"2026-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13458019/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148711517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}