Case Reports in Rheumatology最新文献_第5页

Corticosteroids, Plasmapheresis, Argatroban, Rituximab, and Sirolimus Provided Clinical Benefit for Catastrophic Antiphospholipid Syndrome in a Patient with a History of Heparin-Induced Thrombocytopenia. 皮质类固醇、血浆置换、阿加曲班、利妥昔单抗和西罗莫司对有肝素诱导的血小板减少史的灾难性抗磷脂综合征患者有临床疗效。

Case Reports in Rheumatology Pub Date : 2023-01-01 DOI: 10.1155/2023/3226278

Haytham Hasan, Ivana Surjancev, Jon A Arnason, Shivani Garg, William Nicholas Rose

引用次数: 0

Time Course of Antispike Antibody Titer after Administration of BNT162b2 mRNA COVID-19 Vaccine in a Patient with Rheumatoid Arthritis on Methotrexate. 甲氨蝶呤类风湿性关节炎患者BNT162b2 mRNA COVID-19疫苗接种后抗刺突抗体滴度的时间过程

Case Reports in Rheumatology Pub Date : 2023-01-01 DOI: 10.1155/2023/4525249

Satoshi Shinohara, Yasuhiro Hirose

{"title":"Time Course of Antispike Antibody Titer after Administration of BNT162b2 mRNA COVID-19 Vaccine in a Patient with Rheumatoid Arthritis on Methotrexate.","authors":"Satoshi Shinohara, Yasuhiro Hirose","doi":"10.1155/2023/4525249","DOIUrl":"https://doi.org/10.1155/2023/4525249","url":null,"abstract":"Methotrexate, an anchor drug for rheumatoid arthritis, hinders the immunogenicity of mRNA COVID-19 vaccines. Therefore, an optimal vaccine strategy for patients with rheumatoid arthritis receiving methotrexate is vital. We monitored antispike antibody titers after BNT162b2 mRNA COVID-19 vaccination in seven healthcare workers and one methotrexate-treated rheumatoid arthritis patient. The antispike antibody titers of healthcare workers significantly increased immediately after primary vaccination and then continued to decrease, whereas those of the rheumatoid arthritis patient were significantly lower immediately after primary vaccination and then increased. The titers in all participants dramatically increased 1-month postbooster. These changes over time may suggest that in the methotrexate-treated rheumatoid arthritis patient, the generation of short-lived plasma cells was strongly suppressed; in contrast, the generation of long-lived plasma cells and memory B cells was intact. For methotrexate-treated rheumatoid arthritis patients, it is important to complete the primary and booster vaccination series to ensure sufficient immunity against COVID-19.","PeriodicalId":9622,"journal":{"name":"Case Reports in Rheumatology","volume":"2023 ","pages":"4525249"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10132894/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9387112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rare Presentation of Disseminated Gout Nodulosis and Chronic Inflammatory Arthritis. 弥散性痛风结节病和慢性炎性关节炎的罕见表现。

Case Reports in Rheumatology Pub Date : 2023-01-01 DOI: 10.1155/2023/8083212

Faria Sami, Shahzad Ahmed Sami, Shilpa Arora

{"title":"Rare Presentation of Disseminated Gout Nodulosis and Chronic Inflammatory Arthritis.","authors":"Faria Sami, Shahzad Ahmed Sami, Shilpa Arora","doi":"10.1155/2023/8083212","DOIUrl":"https://doi.org/10.1155/2023/8083212","url":null,"abstract":"Background: Gout is an inflammatory arthritis caused by monosodium urate (MSU) deposition. Acute gout is a dramatic painful swelling of the joint; however, MSU can deposit in other tissues as well, including skin, gastrointestinal tract, and bones over time. Disseminated tophi in the skin are a rare presentation of gout known as gout nodulosis. We present a case of gout nodulosis with subcutaneous diffuse miliary nodules in nonarticular areas with concurrent findings suggestive of chronic inflammatory arthritis. Case Presentation. A 39-year-old patient presented with intermittent painful swelling in multiple joints with prolonged morning stiffness. On exam, synovitis was present in multiple proximal interphalangeal joints, wrists, elbows, and knees. Chronic raised pearly nodular rash and swellings on extensor aspects of arms, legs, and anterior abdomen were noticeable. He had negative rheumatoid factor and anti-CCP antibody, C-reactive protein of 0.23 mg/dL, erythrocyte sedimentation rate of 37 mm/hr, and uric acid of 10.6 mg/dL. Hand X-rays revealed severe periarticular osteopenia and joint space narrowing in several joints. Musculoskeletal ultrasound showed a double contour sign at multiple joints and a tophaceous deposit over the olecranon fossa. The biopsy of the nodular rash was consistent with tophi. He was diagnosed with chronic tophaceous gout with skin nodulosis and possible overlap of seronegative rheumatoid arthritis given his X-ray findings.Conclusion: This case discusses one of the rare presentations of gout with disseminated gouty tophi in the skin to raise clinical awareness. The clinical dilemma of the overlap of gout and rheumatoid arthritis posing a diagnostic challenge for clinicians is also highlighted.","PeriodicalId":9622,"journal":{"name":"Case Reports in Rheumatology","volume":"2023 ","pages":"8083212"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10284652/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10070065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Coexistent Relapsing Polychondritis and Clinically Amyopathic Dermatomyositis: A Rare Association of Autoimmune Disorders. 复发性多软骨炎和临床淀粉性皮肌炎共存:一种罕见的自身免疫性疾病关联。

Case Reports in Rheumatology Pub Date : 2023-01-01 DOI: 10.1155/2023/3719502

Rafael A Ríos-Rivera, Luis M Vilá

{"title":"Coexistent Relapsing Polychondritis and Clinically Amyopathic Dermatomyositis: A Rare Association of Autoimmune Disorders.","authors":"Rafael A Ríos-Rivera, Luis M Vilá","doi":"10.1155/2023/3719502","DOIUrl":"https://doi.org/10.1155/2023/3719502","url":null,"abstract":"Relapsing polychondritis (RPC) is an uncommon autoimmune systemic disease characterized by recurrent inflammation of the cartilage tissue. It can occur alone or in association with other autoimmune diseases, vasculitis, or hematologic disorders. However, the association of RPC with dermatomyositis is extremely rare. Herein, we present a case of a 38-year-old man who developed concurrent RPC and clinically amyopathic dermatomyositis (CADM) manifested by auricular chondritis, nasal chondritis, polyarthritis, gottron papules, fingertip papules, skin biopsy consistent with dermatomyositis, and positive antimelanoma differentiation-associated gene 5 (MDA5) antibodies. RPC features resolved with corticosteroids, but CADM manifestations were resistant to corticosteroids, cyclophosphamide, azathioprine, and hydroxychloroquine. Subsequent therapy with rituximab was effective to control CADM manifestations. This case highlights the importance of recognizing CADM as part of the autoimmune diseases linked with RPC and maintaining a high level of awareness to initiate effective therapy to avoid the long-term complications associated with these conditions.","PeriodicalId":9622,"journal":{"name":"Case Reports in Rheumatology","volume":"2023 ","pages":"3719502"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113061/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9386237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Case Report of Pericardial Effusion with False-Positive Mesothelioma and Adenocarcinoma Markers as the Initial Presentation of Systemic Lupus Erythematous. 心包积液伴假阳性间皮瘤和腺癌标记物为系统性红斑狼疮的首发表现1例报告。

Case Reports in Rheumatology Pub Date : 2022-11-03 eCollection Date: 2022-01-01 DOI: 10.1155/2022/8081055

Gita Bhattacharya, Pritha P Gupta

引用次数: 1

Aftermath of Apixaban: Atypical Anticoagulation Aftereffect. 阿哌沙班后:非典型抗凝后效应。

Case Reports in Rheumatology Pub Date : 2022-10-22 eCollection Date: 2022-01-01 DOI: 10.1155/2022/6221640

Bhesh Karki, Louis Costanzo, Sameer Joshi, Aleksey Fiksman

引用次数: 0

Glomerulonephritis and Interstitial Nephritis Originating from Vasculitis of the Interlobular Arteries of the Kidney in a Patient with Eosinophilic Granulomatosis with Polyangiitis. 嗜酸性肉芽肿病合并多血管炎患者起源于肾脏小叶间动脉血管炎的肾小球肾炎和间质性肾炎。

Case Reports in Rheumatology Pub Date : 2022-09-28 eCollection Date: 2022-01-01 DOI: 10.1155/2022/9606981

Takashi Nawata, Masaki Shibuya, Yukio Takeshita, Makoto Kubo, Noriko Uesugi, Masafumi Yano

引用次数: 1

Rapid Onset and Resolution of Hydroxychloroquine Cardiomyopathy: A Case Report. 羟氯喹心肌病的快速发病和消退:1例报告。

Case Reports in Rheumatology Pub Date : 2022-09-26 eCollection Date: 2022-01-01 DOI: 10.1155/2022/6503453

Ahmad Ramahi, Amer Heider, J Michelle Kahlenberg

引用次数: 0

Nephrotic Syndrome as an Extramuscular Manifestation of Anti-EJ Antibody-Positive Dermatomyositis: A Case Report and Review of the Literature. 肾病综合征作为抗ej抗体阳性皮肌炎的肌外表现:1例报告及文献复习。

Case Reports in Rheumatology Pub Date : 2022-09-20 eCollection Date: 2022-01-01 DOI: 10.1155/2022/1233522

Syoko Tsubouchi, Takahiro Mizuuchi, Yusuke Yamamoto, Daiki Fujimori, Kayo Ishii, Mayu Tago, Eri Kato, Hiroaki Mori, Haeru Hayashi, Koichiro Tahara, Tetsuji Sawada

引用次数: 0

Severe Anti-HMG-CoAR Necrotizing Autoimmune Myopathy Secondary to Statin Use. 他汀类药物继发的严重抗hmg - coar坏死性自身免疫性肌病

Case Reports in Rheumatology Pub Date : 2022-09-16 eCollection Date: 2022-01-01 DOI: 10.1155/2022/6120424

Priyanjali Pulipati, Jayakar Kamantha Reddy, Syed Ali Husain

引用次数: 1