Case Reports in Endocrinology最新文献_第8页

Overcoming Barriers to Diabetes Technology in Youth with Type 1 Diabetes and Public Insurance: Cases and Call to Action 克服青少年1型糖尿病技术障碍和公共保险:案例和行动呼吁

IF 1.1

Case Reports in Endocrinology Pub Date : 2022-03-01 DOI: 10.1155/2022/9911736

Ming Yeh Lee, M. Tanenbaum, D. Maahs, P. Prahalad

{"title":"Overcoming Barriers to Diabetes Technology in Youth with Type 1 Diabetes and Public Insurance: Cases and Call to Action","authors":"Ming Yeh Lee, M. Tanenbaum, D. Maahs, P. Prahalad","doi":"10.1155/2022/9911736","DOIUrl":"https://doi.org/10.1155/2022/9911736","url":null,"abstract":"Advancements in diabetes technology such as continuous glucose monitoring (CGM), insulin pumps, and automated insulin delivery provide opportunities to improve glycemic control for youth with type 1 diabetes (T1D). However, diabetes technology use is lower in youth on public insurance, and this technology use gap is widening in the US. There is a significant need to develop effective interventions and policies to promote equitable care. The dual purpose of this case series is as follows: (1) describe success stories of the CGM Time in Range Program (CGM TIPs), which removed barriers for initiating CGM and provided asynchronous remote glucose monitoring for youth on public insurance, and (2) advocate for improving CGM coverage by public insurance. We describe a series of six youths with T1D and public insurance who obtained and sustained use of CGM with assistance from the program. Three youths had improved engagement with the care team while on CGM and the remote monitoring protocol, and three youths were able to leverage sustained CGM wear to obtain insurance coverage for automated insulin delivery systems. CGM TIPs helped these youths achieve lower hemoglobin A1c and improved time in range (TIR). Despite the successes, expansion of CGM TIPs is limited by stringent barriers for CGM approval and difficult postapproval patient workflows to receive shipments. These cases highlight the potential for combining diabetes technology and asynchronous remote monitoring to support continued use and provide education to improve glycemic control for youth with T1D on public insurance and the need to reduce barriers for obtaining CGM coverage by public insurance.","PeriodicalId":9621,"journal":{"name":"Case Reports in Endocrinology","volume":"38 1","pages":""},"PeriodicalIF":1.1,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89115132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

An Infant with Asymptomatic Vitamin D Intoxication: A Prolonged and Sustainable Recovery 婴儿无症状维生素D中毒:一个长期和可持续的恢复

IF 1.1

Case Reports in Endocrinology Pub Date : 2022-02-27 DOI: 10.1155/2022/7072815

I. Al Alwan, Nouf Al Issa, Yousef Al Anazi, Khalid Al Noaim, M. Z. Mughal, A. Babiker

引用次数: 1

Retracted: A Newborn with Genital Ambiguity, 45,X/46,XY Mosaicism, a Jumping Chromosome Y, and Congenital Adrenal Hyperplasia 缩回:新生儿生殖器模糊，45,X/46,XY嵌合，Y染色体跳跃和先天性肾上腺增生

IF 1.1

Case Reports in Endocrinology Pub Date : 2022-02-22 DOI: 10.1155/2022/9808430

Case Reports in Endocrinology

引用次数: 0

A Tale of Two Hypersecreting Adrenal Neoplasms in the Heartland of COVID-19 Pandemic, Lombardy, Italy 在意大利伦巴第，COVID-19大流行的中心地带，两个高分泌肾上腺肿瘤的故事

IF 1.1

Case Reports in Endocrinology Pub Date : 2022-02-18 DOI: 10.1155/2022/1539203

B. Zampetti, R. Attanasio, E. Carioni, D. Dallabonzana, I. Pauna, M. Boniardi, R. Cozzi

引用次数: 1

Development and Resolution of Secondary Adrenal Insufficiency after an Intra-Articular Steroid Injection. 关节内类固醇注射后继发性肾上腺功能不全的发展和解决。

IF 1.1

Case Reports in Endocrinology Pub Date : 2022-01-01 DOI: 10.1155/2022/4798466

Jia Wei Tan, Sachin K Majumdar

{"title":"Development and Resolution of Secondary Adrenal Insufficiency after an Intra-Articular Steroid Injection.","authors":"Jia Wei Tan, Sachin K Majumdar","doi":"10.1155/2022/4798466","DOIUrl":"https://doi.org/10.1155/2022/4798466","url":null,"abstract":"Corticosteroid injections are commonly indicated in inflammatory conditions involving the soft tissues, tendon sheaths, bursae, and joints. Local corticosteroids carry a lower risk of complications than systemic corticosteroid but may be systemically absorbed and subsequently suppress the hypothalamic-pituitary-adrenal (HPA) axis. This can cause secondary adrenal insufficiency (SAI) as well as iatrogenic Cushing's syndrome. We report a 78-year-old female who presented with nonspecific gastrointestinal symptoms after a recent intra-articular steroid injection in her shoulder. She had hyponatremia, low morning cortisol, and failed to respond to high-dose cosyntropin. Further workup revealed the underlying cause to be SAI. Follow-up testing revealed a recovery of HPA responsiveness within 2 weeks of her initial diagnosis. Conclusion. Our case highlights how the hypothalamic-pituitary axis (HPA) can be suppressed with intra-articular steroids. The threshold to test corticosteroid users for adrenal insufficiency should be low in clinical practice, especially for those patients with nonspecific symptoms after steroid injections. Once diagnosed, temporary treatment with steroids may be required.","PeriodicalId":9621,"journal":{"name":"Case Reports in Endocrinology","volume":"2022 ","pages":"4798466"},"PeriodicalIF":1.1,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800097/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10466575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

BYPASS-OMA: Hypoglycemic Hyperinsulinemic Nesidioblastosis after Gastric Bypass Surgery-A Case Report and Review of the Literature. 胃旁路手术后低血糖性高胰岛素性肾母细胞病1例报告及文献复习。

IF 1.1

Case Reports in Endocrinology Pub Date : 2022-01-01 DOI: 10.1155/2022/5472304

Jessica Cao, Cindy Kim, Thatcher Huynh, Amanda Frugoli, Heidi Henson, Vera Valdez, Tricia Westhoff-Pankratz

{"title":"BYPASS-OMA: Hypoglycemic Hyperinsulinemic Nesidioblastosis after Gastric Bypass Surgery-A Case Report and Review of the Literature.","authors":"Jessica Cao, Cindy Kim, Thatcher Huynh, Amanda Frugoli, Heidi Henson, Vera Valdez, Tricia Westhoff-Pankratz","doi":"10.1155/2022/5472304","DOIUrl":"https://doi.org/10.1155/2022/5472304","url":null,"abstract":"This rare case vignette describes hypoglycemic, hyperinsulinemic nesidioblastosis in a female patient with prior Roux-en-Y gastric bypass. The patient presented with severe symptomatic hypoglycemia resistant to IV dextrose and diazoxide, requiring surgical resection. Traditional imaging found nonspecific findings, and biochemical analysis was inconsistent with insulinoma. A gallium-68 dotatate PET scan was utilized to successfully localize the tumor in the distal pancreas. She underwent laparoscopic resection of the distal pancreatic lesion with resolution of her symptoms and return to euglycemia. The histological evaluation confirmed the diagnosis of nesidioblastosis. Nesidioblastosis is a rare complication of bariatric surgery that may be more clinically relevant with rising prevalence of obesity. Diagnosis with conventional imaging modalities may be challenging; however, the dotatate PET scan may have high utility in detecting lesions. It is essential for clinicians to consider nesidioblastosis in the differential diagnosis of hyperinsulinemic hypoglycemic conditions and recognize there may be a link with increasing rates of bariatric surgery.","PeriodicalId":9621,"journal":{"name":"Case Reports in Endocrinology","volume":"2022 ","pages":"5472304"},"PeriodicalIF":1.1,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800099/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10466576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Spontaneous Adrenal Hemorrhage with Mild Hypoadrenalism in a Patient Anticoagulated with Apixaban for Antiphospholipid Syndrome: A Case Report and Literature Review. 阿哌沙班抗凝治疗抗磷脂综合征患者自发性肾上腺出血伴轻度肾上腺功能减退:1例报告及文献复习。

IF 1.1

Case Reports in Endocrinology Pub Date : 2022-01-01 DOI: 10.1155/2022/6538800

Jia Wei Tan, Anant Shukla, Jiun-Ruey Hu, Sachin K Majumdar

{"title":"Spontaneous Adrenal Hemorrhage with Mild Hypoadrenalism in a Patient Anticoagulated with Apixaban for Antiphospholipid Syndrome: A Case Report and Literature Review.","authors":"Jia Wei Tan, Anant Shukla, Jiun-Ruey Hu, Sachin K Majumdar","doi":"10.1155/2022/6538800","DOIUrl":"https://doi.org/10.1155/2022/6538800","url":null,"abstract":"Background: Adrenal hemorrhage (AH) is a serious endocrine complication of antiphospholipid syndrome (APLS). Case Presentation. We report a 45-year-old man who presented with several deep venous thromboses and was initially treated with apixaban, who later developed bilateral AH. Laboratory findings were consistent with cortisol deficiency yet preserved aldosterone physiology. He was diagnosed with APLS and treated with warfarin. After 8 months of follow-up, he remained on cortisol replacement with no evidence of recovery. We reviewed PubMed/MEDLINE indexed articles from 1950 to 2022 for cases of AH in APLS patients on anticoagulation. Six cases of patients on direct oral anticoagulants (DOACs) were reported. Discussion. The unique vasculature of the adrenal glands creates a \"functional vascular dam\" in the zona reticularis, which is susceptible to thrombosis in situ and hemorrhage. DOACs may further increase the risk of AH.Conclusion: Depending on the degree of adrenal involvement in AH, patients can present with partial or complete primary adrenal insufficiency. More data are needed to characterize adrenal function after AH, and the safety of DOAC versus warfarin in patients with APLS warrants further studies.","PeriodicalId":9621,"journal":{"name":"Case Reports in Endocrinology","volume":"2022 ","pages":"6538800"},"PeriodicalIF":1.1,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9729038/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10331324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Multifocal Multisystem Langerhans Cell Histiocytosis Involving Pituitary Masquerading as Crohn's Disease: A Case Report and Review of the Literature. 垂体多病灶多系统朗格汉斯细胞组织细胞增多症伪装成克罗恩病:1例报告及文献复习。

IF 1.1

Case Reports in Endocrinology Pub Date : 2022-01-01 DOI: 10.1155/2022/4672473

Mohd Ashraf Ganie, Bhanu Malhotra, Manpreet Saini, Arshiya Dutta, Atul Sharma, Kim Vaiphie, Pinaki Dutta

{"title":"Multifocal Multisystem Langerhans Cell Histiocytosis Involving Pituitary Masquerading as Crohn's Disease: A Case Report and Review of the Literature.","authors":"Mohd Ashraf Ganie, Bhanu Malhotra, Manpreet Saini, Arshiya Dutta, Atul Sharma, Kim Vaiphie, Pinaki Dutta","doi":"10.1155/2022/4672473","DOIUrl":"https://doi.org/10.1155/2022/4672473","url":null,"abstract":"Background/Objective. We present a case of Langerhans cell histiocytosis (LCH) with gastrointestinal involvement masquerading as inflammatory bowel disease (IBD) in a patient who initially had features of central diabetes insipidus (CDI). Case Report. A 19-year-old male presented at 14 years of age with central diabetes insipidus. He subsequently developed panhypopituitarism and sellar-suprasellar mass, the biopsy of which was inconclusive. Secondary causes for hypophysitis were ruled out. Five years later, he developed perianal pus discharging sinuses, positive ASCA, and sacroiliitis. Rectal ulcer biopsy showed nonspecific inflammation and necrosis. Hence, he was managed as inflammatory bowel disease (IBD). Due to nonresponsiveness of symptoms, doubt about diagnosis was invoked and rectal ulcer biopsy was repeated, which then showed infiltration by Langerhans cells. Hence, he was diagnosed with LCH and showed resolution of symptoms on initiating steroids and vinblastine. Discussion. Gastrointestinal involvement by LCH is unusual and only rarely has represented a prominent clinical manifestation. In most cases, such involvement suggests widespread multisystem disease. Its distinctive morphologic and immunohistochemical features allow LCH to be distinguished from other inflammatory infiltrations found in mucosal biopsy specimens. Conclusion. Preceding CDI and hypopituitarism may predict LCH in patients with IBD-like diseases.","PeriodicalId":9621,"journal":{"name":"Case Reports in Endocrinology","volume":"2022 ","pages":"4672473"},"PeriodicalIF":1.1,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744597/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10362496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neonatal Cholestasis: A Rare and Unusual Presentation of Pituitary Stalk Interruption Syndrome. 新生儿胆汁淤积症：新生儿胆汁淤积症：垂体茎突中断综合征罕见而不寻常的表现形式

IF 1.1

Case Reports in Endocrinology Pub Date : 2021-05-22 eCollection Date: 2021-01-01 DOI: 10.1155/2021/6161508

R El Qadiry, A Ouayad, H Nassih, A Bourrahouat, I Ait Sab

{"title":"Neonatal Cholestasis: A Rare and Unusual Presentation of Pituitary Stalk Interruption Syndrome.","authors":"R El Qadiry, A Ouayad, H Nassih, A Bourrahouat, I Ait Sab","doi":"10.1155/2021/6161508","DOIUrl":"10.1155/2021/6161508","url":null,"abstract":"Pituitary stalk interruption syndrome (PSIS) is a very rare entity, and the clinical manifestations are nonspecific. Neonatal cholestasis due to endocrine disorders is rare and poorly recognized. Our case report describes a case of PSIS in a Moroccan infant revealed by isolated neonatal cholestasis, which is an unusual presentation in children. Case report. A 40-day-old girl was admitted to our department for progressive cholestatic jaundice appeared on the third day of life. She was born from a non-consanguineous marriage, and her prenatal and perinatal history went without incident. Physical examination showed icteric skin and sclera, without hepatomegaly. Analysis of pituitary hormones revealed panhypopituitarism. On brain magnetic resonance imaging (MRI), the pituitary stalk was absent, the posterior pituitary was ectopic, and the anterior pituitary was hypoplastic. The patient was diagnosed with interrupted pituitary stalk syndrome. The treatment consisted of hormone replacement with rapid improvement of her clinical condition. Conclusion. Panhypopituitarism, a consequence of PSIS, is a rare cause of neonatal cholestasis. However, pediatricians should keep this syndrome in mind for patients who present with neonatal cholestasis.","PeriodicalId":9621,"journal":{"name":"Case Reports in Endocrinology","volume":"2021 ","pages":"6161508"},"PeriodicalIF":1.1,"publicationDate":"2021-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166483/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10593370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Thyrotoxic Periodic Paralysis Causing Back Pain and Leg Weakness: An Unusual Presentation of Hyperthyroidism. 甲状腺毒性周期性麻痹引起背部疼痛和腿部无力:甲亢的一种不寻常的表现。

IF 1.1

Case Reports in Endocrinology Pub Date : 2021-01-01 DOI: 10.1155/2021/6622658

Henrik Elenius, Marie Cesa, Corina C Nava Suarez, Abhishek Nimkar, Prasanta Basak, Nandita Sinha

{"title":"Thyrotoxic Periodic Paralysis Causing Back Pain and Leg Weakness: An Unusual Presentation of Hyperthyroidism.","authors":"Henrik Elenius, Marie Cesa, Corina C Nava Suarez, Abhishek Nimkar, Prasanta Basak, Nandita Sinha","doi":"10.1155/2021/6622658","DOIUrl":"https://doi.org/10.1155/2021/6622658","url":null,"abstract":"Thyrotoxic periodic paralysis (TPP) is a rare muscular disorder, characterized by muscle weakness and hypokalemia triggered by thyrotoxicosis. In Asian populations, 2% of patients with thyrotoxicosis are affected, compared to only 0.1-0.2% of non-Asians. The vast majority of patients are male. Muscle weakness ranges in severity from very mild to life-threatening, due to respiratory compromise. We present a case of a previously healthy 39-year-old Hispanic male who presented with sudden quadriparesis and quickly recovered after being treated for hypokalemia and thyrotoxicosis. TPP, although unusual, is important to recognize as it is a potentially fatal condition that requires close monitoring and is readily reversible with appropriate therapy. Any cause of thyroid hormone excess can cause TPP, with Graves' disease being the most common etiology. Acute treatment includes potassium repletion, while long-term management focuses on determining and treating the cause of thyrotoxicosis, since maintaining a euthyroid state will prevent further episodes of TPP.","PeriodicalId":9621,"journal":{"name":"Case Reports in Endocrinology","volume":"2021 ","pages":"6622658"},"PeriodicalIF":1.1,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435310/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10424322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1