Case Reports in Endocrinology最新文献_第9页

Be(a)ware of Leukocytosis in Papillary Thyroid Cancer. 他(a)注意甲状腺乳头状癌的白细胞增多。

IF 1.1

Case Reports in Endocrinology Pub Date : 2022-07-16 eCollection Date: 2022-01-01 DOI: 10.1155/2022/5799432

Styliani Laskou, Konstantinos Sapalidis, Christos Topalidis, Triantafyllia Koletsa, Isaak Kesisoglou

引用次数: 0

Adrenal Mass in a 70-Year-Old Woman. 70岁女性肾上腺肿块。

IF 1.1

Case Reports in Endocrinology Pub Date : 2022-07-12 eCollection Date: 2022-01-01 DOI: 10.1155/2022/2736199

Kiana Karimi, Mohsen Nikzad, Sohrab Kulivand, Shiva Borzouei

{"title":"Adrenal Mass in a 70-Year-Old Woman.","authors":"Kiana Karimi, Mohsen Nikzad, Sohrab Kulivand, Shiva Borzouei","doi":"10.1155/2022/2736199","DOIUrl":"https://doi.org/10.1155/2022/2736199","url":null,"abstract":"Introduction: Adrenocortical carcinoma is a rare endocrine malignancy with a bimodal age distribution pattern that affects women more than men. More than half of the patients present with hormone excess manifestations such as Cushing's syndrome and virilization. Non-functional tumors usually are diagnosed incidentally following imaging studies due to a mass effect or metastatic disease. Surgical resection is considered the best curative treatment for these tumors. Case Presentation. A 70-year-old woman presented with a 3-month history of diffuse intermittent abdominal discomfort, weight loss, and additional hair growth. Imaging investigations revealed a large 187 × 85 × 140 mm mass between the liver and upper pole of the right kidney which has displaced the adjacent structures. Hormonal evaluations detected high levels of cortisol and adrenal androgens. She underwent open adrenalectomy and right nephrectomy due to severe adhesion of the mass. Histopathological evaluations revealed adrenocortical carcinoma and the patient received adjuvant radiotherapy.Conclusion: Precise physical examination, hormonal evaluation, and imaging studies play a key role in differentiating malignant adrenal masses in all patients, especially in those with vague symptoms. Radical excision of the mass and appropriate adjuvant chemotherapy or radiotherapy improve the outcome for patients.","PeriodicalId":9621,"journal":{"name":"Case Reports in Endocrinology","volume":" ","pages":"2736199"},"PeriodicalIF":1.1,"publicationDate":"2022-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9296303/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40544654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Challenges of Diagnosing Pseudohypoaldosteronism (PHA) in an Infant. 诊断婴儿假性醛固酮减少症(PHA)的挑战。

IF 1.1

Case Reports in Endocrinology Pub Date : 2022-07-11 eCollection Date: 2022-01-01 DOI: 10.1155/2022/9921003

Ghufran Saeed Babar, Minah Tariq

引用次数: 1

Pregnancy in a Transgender Male: A Case Report and Review of the Literature. 跨性别男性怀孕一例报告及文献回顾。

IF 1.1

Case Reports in Endocrinology Pub Date : 2022-06-29 eCollection Date: 2022-01-01 DOI: 10.1155/2022/6246867

Ayesha Hassan, Jessica Perini, Amna Khan, Apoorva Iyer

{"title":"Pregnancy in a Transgender Male: A Case Report and Review of the Literature.","authors":"Ayesha Hassan, Jessica Perini, Amna Khan, Apoorva Iyer","doi":"10.1155/2022/6246867","DOIUrl":"https://doi.org/10.1155/2022/6246867","url":null,"abstract":"Introduction: Pregnancy in transgender men is an area of increasing study due to data showing that pregnancy can occur in this population despite the reduction in fertility that generally accompanies treatment with gender-affirming hormone therapies.Case: In this case, we describe a healthy 21-year-old transgender man who was able to achieve pregnancy without reproductive assistance after stopping his testosterone therapy for 2 months. Discussion. Our case is important as it highlights how little is known in regards to gender-affirming hormone therapy on fertility. While testosterone is known to reduce fertility by inducing anovulation and altering ovarian histology, its long-term effects on conception rates and pregnancy are largely unknown. Some studies demonstrate that transgender men, treated with gender-affirming hormone therapy (GAHT), including testosterone, have similar oocyte quantity and quality, as well as similar ovarian reserve, when compared to cisgender women, suggesting that resumption of fertility may be possible after cessation of GAHT. Long-term outcomes for the pregnancy and the offspring of those who have been treated with GAHT are unknown.Conclusion: Recent studies have shown that pregnancy is possible for transgender men who desire biological children and have received gender-affirming hormonal therapy without fertility-preserving measures. Further research is needed to help determine rates of fertility, the likelihood of recovery of fertility, conception rates, and long-term pregnancy outcomes. Such information would help guide physicians in providing education and counseling to their transgender patients regarding reproductive options.","PeriodicalId":9621,"journal":{"name":"Case Reports in Endocrinology","volume":" ","pages":"6246867"},"PeriodicalIF":1.1,"publicationDate":"2022-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9259284/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40590820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

A Dramatic Response of a Thyroid Lymphoma to R-CHOP Chemotherapy Reversing Mechanical Airway Obstruction and Respiratory Failure. 甲状腺淋巴瘤对R-CHOP化疗逆转机械性气道阻塞和呼吸衰竭的显著反应。

IF 1.1

Case Reports in Endocrinology Pub Date : 2022-06-27 eCollection Date: 2022-01-01 DOI: 10.1155/2022/3719320

Zeinab Alnahas, Mohamad H Horani

{"title":"A Dramatic Response of a Thyroid Lymphoma to R-CHOP Chemotherapy Reversing Mechanical Airway Obstruction and Respiratory Failure.","authors":"Zeinab Alnahas, Mohamad H Horani","doi":"10.1155/2022/3719320","DOIUrl":"https://doi.org/10.1155/2022/3719320","url":null,"abstract":"Primary thyroid lymphoma is an extremely rare thyroid malignancy that usually occurs in patients with preexisting Hashimoto thyroiditis and commonly presents in older women. The most common type is non-Hodgkin's lymphoma of B-cell origin, particularly diffuse large B-cell lymphoma (DLBCL), which is primarily treated with chemotherapy and radiotherapy. We reported an 83-year-old woman with a past medical history of hypothyroidism who suffered dysphagia and dyspnea secondary to a large thyroid mass. Her CT neck scan showed an enlarged thyroid mass with pathological cervical lymphadenopathy and marked tracheal narrowing. The ultrasound-guided biopsy confirmed the diagnosis of DLBCL of the thyroid. A few days later, she experienced respiratory distress and failure that required endotracheal intubation and mechanical ventilation. She was not considered for tracheostomy or surgical interventions, and after discussion with her family, the decision was made to start R-CHOP therapy (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone) which resulted in a marked reduction of the thyroid size and reversal of the mechanical airway obstruction, enabling her extubation. This case report demonstrated the dramatic response of a large thyroid lymphoma to R-CHOP therapy, reducing the thyroid size and its fatal obstructive complications, including mechanical airway obstruction, within a few days of the initiation of R-CHOP therapy.","PeriodicalId":9621,"journal":{"name":"Case Reports in Endocrinology","volume":" ","pages":"3719320"},"PeriodicalIF":1.1,"publicationDate":"2022-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9252716/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40566095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Case of Gitelman Syndrome with Hypercalcemia Secondary to Primary Hyperparathyroidism. Gitelman综合征伴原发性甲状旁腺功能亢进继发高钙血症1例。

IF 1.1

Case Reports in Endocrinology Pub Date : 2022-06-25 eCollection Date: 2022-01-01 DOI: 10.1155/2022/1098222

Zeinab Alnahas, Marko Markov, Mohamad H Horani

引用次数: 0

First Case Report of Arrhythmogenic Right Ventricular Cardiomyopathy Showing Refractory Ventricular Tachycardia Induced by Thyroid Storm due to Graves' Disease. 格雷夫斯病甲状腺风暴致顽固性室性心动过速致心律失常右室心肌病1例报告。

IF 1.1

Case Reports in Endocrinology Pub Date : 2022-06-23 eCollection Date: 2022-01-01 DOI: 10.1155/2022/6078148

Masaki Matsubara, Tomohiro Tanaka, Akinori Wakamiya, Tamiko Tamanaha, Hisashi Makino, Tomonori Tanei, Takeshi Aiba, Kengo Kusano, Kiminori Hosoda

引用次数: 2

A Case of Subacute Thyroiditis following COVID-19 Infection COVID-19感染后亚急性甲状腺炎1例

IF 1.1

Case Reports in Endocrinology Pub Date : 2022-05-31 DOI: 10.1155/2022/2211061

Sameh Samir Elawady, Diwakar Phuyal, R. Shah, L. Mirza

{"title":"A Case of Subacute Thyroiditis following COVID-19 Infection","authors":"Sameh Samir Elawady, Diwakar Phuyal, R. Shah, L. Mirza","doi":"10.1155/2022/2211061","DOIUrl":"https://doi.org/10.1155/2022/2211061","url":null,"abstract":"Background/Objective. Since the start of the pandemic, COVID-19 has been associated with several postinfection complications. Subacute thyroiditis (SAT) is an inflammatory disorder of the thyroid that has been reported in the literature following COVID-19 infection. We report a case of SAT following COVID-19 infection. Case Report. A 33-year-old female presented with neck pain two weeks after resolution of COVID-19 infection. Her thyroid function tests together with ultrasonographic pictures were consistent with SAT. She was treated with three rounds of medrol dose pack without relief. She then required oral prednisone 40 mg per day and ibuprofen 800 mg once daily for another several weeks that eventually resulted in improvement of her symptoms. Discussion. SAT most commonly occurs in females during or after viral infection. The usual course of the disease is hyperthyroidism then hypothyroidism followed by resolution. SAT is clinically diagnosed by lab findings of decreased TSH in the setting of negative thyroid-stimulating and thyroid peroxidase antibodies. All these data are consistent with our case. Conclusion. SAT following COVID-19 infection presents with a similar clinical presentation and course as the classic form of SAT, but we should consider the fact that a high-dose corticosteroid treatment might be necessary for such patients.","PeriodicalId":9621,"journal":{"name":"Case Reports in Endocrinology","volume":"4 1","pages":""},"PeriodicalIF":1.1,"publicationDate":"2022-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89492327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

Primary Hypothyroidism with Pituitary Hyperplasia in an Omani Girl 阿曼女孩原发性甲状腺功能减退伴垂体增生1例

IF 1.1

Case Reports in Endocrinology Pub Date : 2022-05-29 DOI: 10.1155/2022/3382612

Wafa Abdallah Fadle, Ali Al Reesi, Saud Al-Shabibi, Maryam Khamis Al-Badi

引用次数: 0

Central Diabetes Insipidus Induced by Acute Myeloid Leukemia with DNMT3A Mutation 急性髓系白血病伴DNMT3A突变致中枢性尿崩症

IF 1.1

Case Reports in Endocrinology Pub Date : 2022-05-23 DOI: 10.1155/2022/2750146

P. Lakshmanan, Heena Asnani, David Knorr

{"title":"Central Diabetes Insipidus Induced by Acute Myeloid Leukemia with DNMT3A Mutation","authors":"P. Lakshmanan, Heena Asnani, David Knorr","doi":"10.1155/2022/2750146","DOIUrl":"https://doi.org/10.1155/2022/2750146","url":null,"abstract":"Central diabetes insipidus (CDI) is an uncommon complication of acute myeloid leukemia (AML). Patients present with polyuria either preceding or at the time of diagnosis of AML. We describe the case of a 36-year-old male who presented with a subacute onset of polyuria, polydipsia, nocturia, and fatigue. After an extensive workup, he was diagnosed with AML/CMML (chronic myelomonocytic leukemia) with a normal karyotype with DNMT3A, CBFB, and PTPN11 mutations. Further workup of the polyuria with a water deprivation test helped confirm the diagnosis of CDI along with MRI findings suggestive of hypophysitis. In this report, we analyze the clinical workup for AML and CDI and report the possibility of extramedullary leukemic infiltration associated with DNMT3A mutation, which has been reported as one of the mechanisms in the existing literature. We also discuss other theories hypothesized to cause CDI in AML patients with abnormal karyotypes. Our patient progressed to AML from CMML-2 after a cycle of decitabine, with confirmed gingival and presumed central nervous system (CNS) involvement. He is in minimal residual disease (MRD)-negative complete remission after induction with a CNS-active acute lymphoblastic leukemia-2 regimen. He also received double umbilical cord blood transplantation, conditioned with cyclophosphamide, fludarabine, thiotepa, and total body irradiation (TBI) of 4 Gy. This was complicated by engraftment syndrome for which he is currently being managed. CDI of the patient was corrected by desmopressin administration.","PeriodicalId":9621,"journal":{"name":"Case Reports in Endocrinology","volume":"13 1","pages":""},"PeriodicalIF":1.1,"publicationDate":"2022-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78498028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1