Case Reports in Dermatology最新文献_第9页

Treatment of Condylomata Acuminata Using a New Non-Vapor-Generating Focused Ultrasound Method following Imiquimod 5% Cream. 5%咪喹莫特乳膏后无蒸汽聚焦超声治疗尖锐湿疣。

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Case Reports in Dermatology Pub Date : 2022-09-01 DOI: 10.1159/000525896

Jacek Calik, Tomasz Zawada, Torsten Bove

{"title":"Treatment of Condylomata Acuminata Using a New Non-Vapor-Generating Focused Ultrasound Method following Imiquimod 5% Cream.","authors":"Jacek Calik, Tomasz Zawada, Torsten Bove","doi":"10.1159/000525896","DOIUrl":"https://doi.org/10.1159/000525896","url":null,"abstract":"Condylomata acuminata is the most common sexually transmitted disease in the world. Physical treatments include excision, cryotherapy, electrocautery and ablative CO2, and Nd:YAG laser ablation, while topical treatments include imiquimod immunotherapy and antimitotic podophyllotoxin or sinecatechins. Efficacies of all methods are low, and recurrences are very common. A new combined method is presented as a single case in a 25-year-old male patient diagnosed with numerous condylomas on the penis, scrotum, and lower abdomen. The treatment consisted of a 7-week topical monotherapy using 5% imiquimod cream followed by local treatment with 20 MHz high-intensity focused ultrasound on remaining recalcitrant lesions. Results showed resolution of approximately 70% of the condylomas after imiquimod treatment, and full resolution of all recalcitrant condylomas treated subsequently with high-intensity focused ultrasound. The method is concluded to be safe and effective and, furthermore, presents a new physical method that does not generate airborne infectious human papillomavirus particles that pose a health risk for the medical team performing therapy. Further studies in larger populations are recommended to confirm the combined efficacy of the proposed method.","PeriodicalId":9619,"journal":{"name":"Case Reports in Dermatology","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a4/d6/cde-0014-0275.PMC9941760.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10830856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

A Report of Unusual Case of Acquired Dermal Melanocytosis on the Scalp of a Caucasian Man with a Literature Review. 一名白人男性头皮罕见获得性皮肤黑色素细胞增多症病例报告并文献复习。

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Case Reports in Dermatology Pub Date : 2022-09-01 DOI: 10.1159/000528353

Fatemeh Mohaghegh, Parvin Rajabi, Samin Nabavinejad, Elham Tavousi Tabatabaei

引用次数: 0

Successful Novel Treatment of Nonuremic Calciphylaxis with Sodium Thiosulfate and Iloprost: A Case Report. 用硫代硫酸钠和依洛前列素成功治疗非尿毒症性钙化:一例报告。

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Case Reports in Dermatology Pub Date : 2022-09-01 DOI: 10.1159/000525712

Lisa Wiltfang, Nina Booken, Stefan W Schneider

引用次数: 0

Acute Disseminated Panniculitis Associated with Alpha-1 Antitrypsin Deficiency. 急性播散性胰膜炎与α -1抗胰蛋白酶缺乏相关。

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Case Reports in Dermatology Pub Date : 2022-09-01 DOI: 10.1159/000526156

António Guilherme Murinello, Helena Sá Damásio, Pedro Guedes, António Manuel de Figueiredo, Adriana Santos, Ana Serrano

引用次数: 0

Epidermolysis Bullosa and Rickets in a 21-Year-Old Female: A Case Report. 21岁女性大疱性表皮松解症合并佝偻病1例。

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Case Reports in Dermatology Pub Date : 2022-09-01 DOI: 10.1159/000525068

Renni Yuniati, Rakhma Yanti Hellmi, Gema Citra Dwijayanti, Meira Dewi Kusuma Astuti, Gerard Pals, Dimitra Micha, Sultana Mh Faradz

{"title":"Epidermolysis Bullosa and Rickets in a 21-Year-Old Female: A Case Report.","authors":"Renni Yuniati, Rakhma Yanti Hellmi, Gema Citra Dwijayanti, Meira Dewi Kusuma Astuti, Gerard Pals, Dimitra Micha, Sultana Mh Faradz","doi":"10.1159/000525068","DOIUrl":"https://doi.org/10.1159/000525068","url":null,"abstract":"Epidermolysis bullosa (EB) is a group of rare genetic diseases that exhibit mechanical fragility of the skin. This condition will result in the occurrence of skin blisters, skin erosions, and skin ulcerations when the skin is subjected to trauma. In this case report, we present a case of EB and multiple skeletal deformities in a 21-year-old female. She came to our clinic with recurrent skin exfoliations and blisters that occurred since she was 4 years old and multiple bones bowing since she was 9 years old. On physical examinations, we found generalized hypopigmentation macule with erythematous skin. There were numerous bullae and crusted lesions, with erosion and excoriations on the lesions. Laboratory examinations identified low vitamin D 25-OH (8.6 ng/mL). Bone densitometry measurement found low bone density, and X-ray examination found osteopenia and bone bowing. Using whole-exome sequencing, no causative pathogenic sequence or copy number variants in the genes associated with Mendelian inherited disorders were detected. The low levels of vitamin D 25-OH may most likely be the main reason for the occurrence of rickets in this patient aside from the genetic disorder.","PeriodicalId":9619,"journal":{"name":"Case Reports in Dermatology","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/30/96/cde-0014-0291.PMC9941763.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10772785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Inflammation of Actinic Keratoses Induced by Combination of Carboplatin and Paclitaxel: Two Case Reports. 卡铂联合紫杉醇致光化性角化病炎症2例。

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Case Reports in Dermatology Pub Date : 2022-09-01 DOI: 10.1159/000528128

Špela Šuler Baglama, Anja Trajber Horvat, Irena Peteln, Gregor Borut Ernst Jemec

引用次数: 0

Dupilumab-Induced Lichen Planus: A Case with Oral and Cutaneous Eruptions. 杜匹单抗诱导的扁平苔藓:1例口腔和皮肤皮疹。

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Case Reports in Dermatology Pub Date : 2022-09-01 DOI: 10.1159/000527918

Laura Kern, Luisa Kleinheinrich, Robert Feldmann, Paul Sator, Alexander Stella, Friedrich Breier

{"title":"Dupilumab-Induced Lichen Planus: A Case with Oral and Cutaneous Eruptions.","authors":"Laura Kern, Luisa Kleinheinrich, Robert Feldmann, Paul Sator, Alexander Stella, Friedrich Breier","doi":"10.1159/000527918","DOIUrl":"https://doi.org/10.1159/000527918","url":null,"abstract":"Lichen planus is a chronic, inflammatory, immune-mediated dermatosis affecting the patient’s skin, scalp, mucous membranes, and nails. Drug-induced lichen planus is described after the administration of antimalarials, ß-blockers, methyldopa, NSAIDs, penicillamines, and sodium aurothiomalate. The use of biologicals such as adalimumab, etanercept, and infliximab has also been linked with the appearance of lichenoid eruptions in the recent past. In this case, we report on a patient developing oral and cutaneous lichen planus after the administration of dupilumab. The lichenoid lesions occurred after 11 months of the drug’s administration and involved the buccal walls, trunk, and extremities. Dupilumab had been administered in an effort to counter severe atopic dermatitis exacerbations. Dupilumab is associated with a downregulation of T-helper 2 cell activation by blocking the Interleukin-4/Interleukin-13 pathway, so leading to a TH1/TH2 imbalance. This imbalance may cause a shift toward a TH1-mediated immune response and be an explanation for the drug-induced lichen planus. Dupilumab was discontinued, and the patient was treated with oral corticosteroids and UVB phototherapy, leading to a significant improvement in the lichen planus lesions.","PeriodicalId":9619,"journal":{"name":"Case Reports in Dermatology","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d9/00/cde-0014-0356.PMC9841792.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10548421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Acoustic Wave Therapy for the Treatment of Extensive Scar Fields: A Case Report. 声波疗法治疗大面积瘢痕:1例报告。

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Case Reports in Dermatology Pub Date : 2022-09-01 DOI: 10.1159/000525070

C Bettina Rümmelein, Ikonija Koceva

引用次数: 0

Tocilizumab-Induced Erythema Annulare Centrifugum. tocilizumab诱导的离心环形红斑。

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Case Reports in Dermatology Pub Date : 2022-09-01 DOI: 10.1159/000526938

Ana Luísa João, Tomás Pessoa E Costa, Paulo Barreto, André Lencastre

{"title":"Tocilizumab-Induced Erythema Annulare Centrifugum.","authors":"Ana Luísa João, Tomás Pessoa E Costa, Paulo Barreto, André Lencastre","doi":"10.1159/000526938","DOIUrl":"https://doi.org/10.1159/000526938","url":null,"abstract":"We report the case of a 42-year-old woman with rheumatoid arthritis undergoing treatment with subcutaneous tocilizumab for the past 6 months. Three days after the administration, an asymptomatic inflammatory annular plaque of 4 cm with discrete whitish scales at the inner border margin developed at the injection site in the left iliac fossa. A smaller plaque in the left groin appeared soon after. The mycological exam was negative. Histology showed a lymphoplasmacytic superficial and deep perivascular, and periadnexal, dermal infiltrate, without epidermal changes. Lesions spontaneously regressed in 4 months. The diagnosis was clinically and histologically consistent with erythema annulare centrifugum, following the exclusion of other differential diagnoses. Erythema annulare centrifugum represents a delayed-type hypersensitivity reaction generally considered idiopathic or otherwise related to numerous triggers, including drugs such as biologics. We describe the first reported case of tocilizumab-induced erythema annulare centrifugum. This case should alert dermatologists to this relatively rare and complex entity and should raise awareness to cutaneous biologic drug reactions.","PeriodicalId":9619,"journal":{"name":"Case Reports in Dermatology","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/53/eb/cde-0014-0302.PMC9941759.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10830858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Six Cases of Erythrodermic Pemphigus Foliaceus: A Case Report. 红皮病性天疱疮6例报告。

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Case Reports in Dermatology Pub Date : 2022-09-01 DOI: 10.1159/000525382

Natsumi Norikawa, Shohei Igari, Masato Ishikawa, Tatsuhiko Mori, Tomoko Hiraiwa, Nobuyuki Kikuchi, Yuka Hanami, Toshiyuki Yamamoto

{"title":"Six Cases of Erythrodermic Pemphigus Foliaceus: A Case Report.","authors":"Natsumi Norikawa, Shohei Igari, Masato Ishikawa, Tatsuhiko Mori, Tomoko Hiraiwa, Nobuyuki Kikuchi, Yuka Hanami, Toshiyuki Yamamoto","doi":"10.1159/000525382","DOIUrl":"https://doi.org/10.1159/000525382","url":null,"abstract":"Pemphigus foliaceus (PF) is one of the causes of erythroderma; however, to date, there have been relatively few reported cases. We herein describe 6 cases of erythrodermic PF. In all 6 cases, PF was a direct cause of erythroderma because the patients had not undergone any medical treatments and neither had any other skin diseases nor were taking any drugs that typically cause erythroderma. Serum levels of IgE and thymus and activation-regulated chemokine were elevated in 5 of the 6 cases, whereas soluble interleukin-2 receptor and squamous cell carcinoma-related antigen were markedly increased in all cases, suggesting that those markers are strong indicators of skin surface damage. All patients were treated with predonisolon (PSL), of which PSL pulse was added in 4 patients and intravenous immunoglobulin was added in 4 patients. Furthermore, all patients except for one were older adults, among whom 2 cases developed Kaposi's varicelliform eruption, and died, and another 2 patients, respectively, died of gastrointestinal bleeding and sepsis. Kaposi's varicelliform eruption is a complication of erythrodermic PF associated with poor prognosis, and thus caution is necessary when considering the diagnosis. Furthermore, elderly people are more likely to have complications due to PSL, which may result in death. Inappropriate treatment and delay in treatment may cause erythroderma, so early diagnosis and treatment are necessary.","PeriodicalId":9619,"journal":{"name":"Case Reports in Dermatology","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/23/83/cde-0014-0258.PMC9947519.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10794221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1