Canadian Journal of Diabetes最新文献_第4页

Virtual vs In-person Care in Gestational Diabetes Management: A Retrospective Cohort Analysis 致编辑的信：妊娠糖尿病管理中的虚拟与面对面护理：回顾性队列分析。

IF 2.7 4区医学

Canadian Journal of Diabetes Pub Date : 2026-06-01 Epub Date: 2025-06-13 DOI: 10.1016/j.jcjd.2025.06.003

Shorrem Naeem MBBS Student, Zainab Arif MBBS Student

引用次数: 0

Uptake and Factors Associated with COVID-19 Vaccination Among 3,779,733 Adults Living With and Without Diabetes: A Population Cohort Study in a Universal Health-care Setting 致编辑的信：在3779733名患有和不患有糖尿病的成年人中，与COVID-19疫苗接种相关的摄取和因素：一项全民卫生保健环境中的人群队列研究。

IF 2.7 4区医学

Canadian Journal of Diabetes Pub Date : 2026-06-01 Epub Date: 2025-06-02 DOI: 10.1016/j.jcjd.2025.05.008

Syed Aaraiz Ul Hassan MBBS, Krishna Jaipal Lohana MBBS, Shorrem Naeem MBBS

引用次数: 0

Barriers to Type 2 Diabetes Management in Australian Gay Cisgender Men: First National Study 澳大利亚男同性恋者管理2型糖尿病的障碍：首次全国性研究。

IF 2.7 4区医学

Canadian Journal of Diabetes Pub Date : 2026-06-01 Epub Date: 2026-01-20 DOI: 10.1016/j.jcjd.2026.01.003

Edwin Pascoe PhD, RN CDE, Jo-Anne Rayner PhD, Trish Burton PhD, Margaret Malloch PhD, FRSA, Gabriella Pretto DEdResearch

{"title":"Barriers to Type 2 Diabetes Management in Australian Gay Cisgender Men: First National Study","authors":"Edwin Pascoe PhD, RN CDE, Jo-Anne Rayner PhD, Trish Burton PhD, Margaret Malloch PhD, FRSA, Gabriella Pretto DEdResearch","doi":"10.1016/j.jcjd.2026.01.003","DOIUrl":"10.1016/j.jcjd.2026.01.003","url":null,"abstract":"<div><h3>Objectives</h3><div>The study sought to determine how sexual orientation impacts the experience and management of type 2 diabetes (T2D) because psychosocial factors are known to have a significant impact on clinical outcomes. This was to address the gap in research on how Australian men assigned male at birth who identify as male and gay may influence the management of T2D and improve awareness among health-care providers and gay men living with T2D.</div></div><div><h3>Methods</h3><div>A sequential mixed-methods design was used to explore the experiences of Australian men assigned male at birth, who identify as male and gay with T2D. Two data collection phases started with an electronic survey of 83 gay men with T2D (7 screening questions and 63 questions covering characteristics and where sexuality and diabetes intersect) and 82 without T2D (5 questions covering thoughts on gay men with T2D), to explore community perceptions, followed by a second phase of 12 in-depth interviews with gay men with T2D.</div></div><div><h3>Results</h3><div>Descriptive statistics were used to analyze the survey data, and a reflexive thematic analysis, grounded in constructivist assumptions, was used for interview data. Twenty-one percent of participants had not disclosed their sexual orientation to their doctor, indicating a prevalent barrier. Three themes emerged that reduce the ability of gay men to bring their whole selves into health-care consultations, creating a barrier, including 1) discomfort around sexual orientation and diabetes; 2) navigating uncomfortable patient–provider conversations; and 3) sexuality and diabetes: unrecognized connections in lifestyle factors.</div></div><div><h3>Conclusions</h3><div>These findings underscore the need for tailored interventions by diabetes specialists or educators to address identity-related barriers and potentially reduce diabetes-related complications.</div></div>","PeriodicalId":9565,"journal":{"name":"Canadian Journal of Diabetes","volume":"50 4","pages":"Pages 217-223"},"PeriodicalIF":2.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146031991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Building a Hybrid Future: Health-care Professionals’ Perspectives on Virtual Pediatric Diabetes Care in British Columbia 构建混合未来：不列颠哥伦比亚省医疗保健专业人员对虚拟儿科糖尿病护理的看法。

IF 2.7 4区医学

Canadian Journal of Diabetes Pub Date : 2026-06-01 Epub Date: 2026-02-16 DOI: 10.1016/j.jcjd.2026.02.004

Aslı E. Özer MA, Sarah Moreheart PhD, Joseph M.W.S. Leung MD, MPH, Devon Greyson PhD, Brenden E. Hursh MD, MHSc, FRCPC

{"title":"Building a Hybrid Future: Health-care Professionals’ Perspectives on Virtual Pediatric Diabetes Care in British Columbia","authors":"Aslı E. Özer MA, Sarah Moreheart PhD, Joseph M.W.S. Leung MD, MPH, Devon Greyson PhD, Brenden E. Hursh MD, MHSc, FRCPC","doi":"10.1016/j.jcjd.2026.02.004","DOIUrl":"10.1016/j.jcjd.2026.02.004","url":null,"abstract":"<div><h3>Objectives</h3><div>Virtual care adoption in pediatric type 1 diabetes (T1D) accelerated during the COVID-19 pandemic, yet little is known about the perspectives of pediatric health-care professionals (HCPs). To identify how HCPs navigate and are impacted by pediatric diabetes virtual care, we explored their experiences with virtual care in British Columbia (BC).</div></div><div><h3>Methods</h3><div>The study team purposively recruited HCPs from across the province. Semistructured interviews were conducted with 32 pediatric HCPs across BC (September 2023 to September 2024). Data were analyzed using inductive thematic analysis informed by the BC Health Quality Matrix.</div></div><div><h3>Results</h3><div>HCPs valued virtual visits for flexibility, safety, accessibility, and efficiency. However, challenges included rapport loss, inability to perform physical assessments, and concerns related to inequities in technology access. Virtual care impacted HCPs' well-being in complex ways, with some reporting benefits but others facing challenges.</div></div><div><h3>Conclusions</h3><div>Pediatric HCPs view virtual care as both beneficial and challenging, recognizing it as a valuable supplement, not a replacement, for in-person visits. As our understanding of these tensions deepens, addressing care gaps and implementing informed strategies will be essential for sustainable, high-quality virtual diabetes care and broader system integration.</div></div>","PeriodicalId":9565,"journal":{"name":"Canadian Journal of Diabetes","volume":"50 4","pages":"Pages 257-265.e4"},"PeriodicalIF":2.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146222094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sexual Quality of Life and Help-seeking Preferences in Adults With Diabetes in Primary Care: A Cross-sectional Study 初级保健中成人糖尿病患者的性生活质量和求助偏好：一项横断面研究

IF 2.7 4区医学

Canadian Journal of Diabetes Pub Date : 2026-06-01 Epub Date: 2026-02-16 DOI: 10.1016/j.jcjd.2026.02.003

Eda Orhan MD, Oğulcan Çöme MD, Gizem Limnili MD, Dilek Guldal MD

{"title":"Sexual Quality of Life and Help-seeking Preferences in Adults With Diabetes in Primary Care: A Cross-sectional Study","authors":"Eda Orhan MD, Oğulcan Çöme MD, Gizem Limnili MD, Dilek Guldal MD","doi":"10.1016/j.jcjd.2026.02.003","DOIUrl":"10.1016/j.jcjd.2026.02.003","url":null,"abstract":"<div><h3>Objectives</h3><div>Diabetes mellitus (DM) can negatively affect sexual health through vascular, neurologic, hormonal, and psychosocial pathways. Despite the high burden of diabetes-related sexual problems, patients’ needs are often overlooked in primary care due to stigma and communication barriers. Understanding determinants of sexual quality of life and patient perspectives may support better integration of sexual health care into diabetes management. Thus, our aim in this study was to assess the sexual quality of life (SQoL) among adults with DM and examine its associations with sociodemographic and clinical factors, as well as attitudes, and expectations regarding sexual health discussions in primary care.</div></div><div><h3>Methods</h3><div>This analytical cross-sectional study included 326 sexually active adults with DM recruited from primary care clinics in Izmir, Türkiye. Data were collected through interviewer-administered questionnaires that captured demographic/clinical characteristics, SQoL (SQoL-F/SQoL-M), and patients’ attitudes and expectations regarding sexual health communication. Statistical analyses included group comparisons, correlations, and multiple linear regression.</div></div><div><h3>Results</h3><div>Older age and longer diabetes duration were independently associated with lower SQoL scores. More favourable attitudes toward discussing sexual health were linked to being male, younger, and more educated. Preference for clinician-initiated communication was greater among women, more educated individuals, and those with longer disease duration. SQoL correlated moderately with attitude scores but not expectation scores.</div></div><div><h3>Conclusions</h3><div>Sexual well-being in diabetes is shaped by age, disease course, and communication-related beliefs. Routine, proactive inquiry by family physicians, supported by culturally sensitive communication, may reduce barriers and improve sexual health outcomes in diabetes care.</div></div>","PeriodicalId":9565,"journal":{"name":"Canadian Journal of Diabetes","volume":"50 4","pages":"Pages 250-256.e1"},"PeriodicalIF":2.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146222360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Peroxisome Proliferator-activated Receptors in Diabetic Retinopathy: Pathophysiologic Insights and Emerging Pharmacologic Strategies 糖尿病视网膜病变中的ppar：病理生理学见解和新兴药理策略。

IF 2.6 4区医学

Canadian Journal of Diabetes Pub Date : 2026-04-01 Epub Date: 2026-02-06 DOI: 10.1016/j.jcjd.2026.01.007

Lorena Mandujano-Ferrer MSc , Diana Alemán-González-Duhart PhD

{"title":"Peroxisome Proliferator-activated Receptors in Diabetic Retinopathy: Pathophysiologic Insights and Emerging Pharmacologic Strategies","authors":"Lorena Mandujano-Ferrer MSc , Diana Alemán-González-Duhart PhD","doi":"10.1016/j.jcjd.2026.01.007","DOIUrl":"10.1016/j.jcjd.2026.01.007","url":null,"abstract":"<div><div>Diabetic retinopathy (DR) is a leading cause of vision loss among working-age adults and one of the most frequent complications of diabetes mellitus. Current therapies, including laser photocoagulation and intravitreal anti–vascular endothelial growth factor (anti-VEGF) agents, are effective only in advanced disease and remain invasive and palliative. The multifactorial pathogenesis of DR involves hyperglycemia-driven oxidative stress, chronic inflammation, dyslipidemia, and disruption of the blood–retinal barrier. Peroxisome proliferator-activated receptors (PPARs) have emerged as key regulators of metabolic and inflammatory signalling in the retina. PPAR-alpha agonists, such as fenofibrate and pemafibrate, exert antioxidant, anti-inflammatory, and vasoprotective effects, whereas PPAR-gamma agonists (e.g. pioglitazone) improve insulin sensitivity and attenuate oxidative damage, albeit with safety concerns such as fluid retention. Dual PPARα/γ agonists, including saroglitazar, provide synergistic benefits by reducing leukostasis, neovascularization, and inflammatory signalling, whereas PPAR-β/δ is gaining attention for its role in retinal energy metabolism. In parallel, non-PPAR targets, such as the advanced glycation end product–receptor for advanced glycation end product (AGE-RAGE) axis, VEGF signalling, aldose reductase, and adenosine monophosphate-activated protein kinase pathways, represent complementary mechanisms. Natural compounds (e.g. curcumin, resveratrol), statins, and metabolic modulators have demonstrated promising preclinical efficacy. Targeting both PPAR and non-PPAR pathways may enable preventive and multimodal management of DR. Future efforts should prioritize early-stage interventions, combination strategies, and innovative ocular drug-delivery systems to overcome current therapeutic limitations and shift from reactive to preventive care.</div></div>","PeriodicalId":9565,"journal":{"name":"Canadian Journal of Diabetes","volume":"50 3","pages":"Pages 183-190"},"PeriodicalIF":2.6,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146144388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diabetes Risk Is Increased in First Nations and Non–First Nations Offspring of Mothers With Diabetes and Worsened Among Those Large for Gestational Age: Results From the DIP: ORRIIGENSS Project 来自DIP: origin项目的结果：第一民族和非第一民族的糖尿病母亲的后代患糖尿病的风险增加，而孕龄较大的后代患糖尿病的风险更大。

IF 2.6 4区医学

Canadian Journal of Diabetes Pub Date : 2026-04-01 Epub Date: 2025-12-31 DOI: 10.1016/j.jcjd.2025.12.012

Roland F. Dyck MD , Chandima Karunanayake PhD , Punam Pahwa PhD , Nathaniel D. Osgood PhD

{"title":"Diabetes Risk Is Increased in First Nations and Non–First Nations Offspring of Mothers With Diabetes and Worsened Among Those Large for Gestational Age: Results From the DIP: ORRIIGENSS Project","authors":"Roland F. Dyck MD , Chandima Karunanayake PhD , Punam Pahwa PhD , Nathaniel D. Osgood PhD","doi":"10.1016/j.jcjd.2025.12.012","DOIUrl":"10.1016/j.jcjd.2025.12.012","url":null,"abstract":"<div><h3>Objectives</h3><div>Our aim in this study was to determine how birthweight and exposure to diabetes in pregnancy (DIP) contribute to early-onset diabetes mellitus (DM) in Saskatchewan First Nations (FN) and non-FN offspring.</div></div><div><h3>Methods</h3><div>Using Ministry of Health administrative databases, we conducted a retrospective cohort study of FN and non-FN children born between 1980 and 2009 and followed to March 31, 2013. Using Cox regression models and cumulative survival analysis, we determined DM risk by birthweight (small [SGA], normal [NGA], or large for gestational age [LGA]), maternal diabetes in pregnancy (DIP) (gestational diabetes [GDM], pre-existing diabetes [pre-Gest/DM], or no DIP), and ethnicity.</div></div><div><h3>Results</h3><div>Among 360,508 offspring, 763 of 52,818 (1.4%) FN and 2,143 of 307,696 (0.7%) non-FN developed DM. FN people were over twice as likely as non-FN to develop DM, but the strongest DM predictor in both populations was DIP exposure (hazard ratios [HRs] 4.1 for FN and 4.9 for non-FN exposed to pre-Gest/DM; HRs 3.1 and 1.6 for FN and non-FN exposed to GDM). SGA and LGA were independent DM predictors in the total population, but only LGA interacted with DIP exposure to amplify DM risk in offspring. By 34 years, 38% of LGA FN (9% of non-FN) people exposed to pre-Gest/DM and 22% of LGA FN (4% of non-FN) people exposed to GDM developed DM.</div></div><div><h3>Conclusions</h3><div>GDM is a key to the epidemic of T2DM among Indigenous peoples. It is the strongest predictor of T2DM among younger FN women and a precursor to their high rates of pre-Gest/DM. Offspring exposed to GDM and especially pre-Gest/DM are at high risk for early-onset T2DM, further worsened by being LGA.</div></div>","PeriodicalId":9565,"journal":{"name":"Canadian Journal of Diabetes","volume":"50 3","pages":"Pages 153-161.e2"},"PeriodicalIF":2.6,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145893501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cannabis Hyperemesis Syndrome Can Mimic Diabetic Gastroparesis in Cannabis Users With Type 1 Diabetes 致编辑的信：大麻呕吐综合征可以模仿1型糖尿病大麻使用者的糖尿病胃轻瘫。

IF 2.6 4区医学

Canadian Journal of Diabetes Pub Date : 2026-04-01 Epub Date: 2025-05-24 DOI: 10.1016/j.jcjd.2025.05.004

Syeda Kashaf Batool MBBS, Fatima Asif MBBS, Muhammad Owais MBBS

引用次数: 0

A Retrospective Analysis of Postpartum Glucose Testing Incidence by Prenatal Care Provider Specialty in a Canadian Gestational Diabetes Cohort “致编辑：加拿大妊娠糖尿病队列中产前护理人员专业对产后血糖检测发生率的回顾性分析。”

IF 2.6 4区医学

Canadian Journal of Diabetes Pub Date : 2026-04-01 Epub Date: 2025-05-26 DOI: 10.1016/j.jcjd.2025.05.003

Syed Aaraiz Ul Hassan MBBS, Noor Ul Huda MBBS, Noor Un Nisa MBBS

引用次数: 0

Validation of the Canadian Diabetes Risk Questionnaire Tool Among Young African, Caribbean, and Black Adults Living in Canada 加拿大糖尿病风险问卷（CANRISK）工具在居住在加拿大的年轻非洲、加勒比和黑人（ACB）成年人中的验证。

IF 2.6 4区医学

Canadian Journal of Diabetes Pub Date : 2026-04-01 Epub Date: 2025-12-08 DOI: 10.1016/j.jcjd.2025.11.003

Susanna Abraham Cottagiri MSc , Sebastian Srugo MSc , Stephanie Cerutti MA , Akm Alamgir PhD , Victor Adarquah PhD , Devi Raghunauth MScPH, MBBS , Amna Iqbal MPK , Rojiemiahd Edjoc PhD , Ying Jiang MD, MSc

{"title":"Validation of the Canadian Diabetes Risk Questionnaire Tool Among Young African, Caribbean, and Black Adults Living in Canada","authors":"Susanna Abraham Cottagiri MSc , Sebastian Srugo MSc , Stephanie Cerutti MA , Akm Alamgir PhD , Victor Adarquah PhD , Devi Raghunauth MScPH, MBBS , Amna Iqbal MPK , Rojiemiahd Edjoc PhD , Ying Jiang MD, MSc","doi":"10.1016/j.jcjd.2025.11.003","DOIUrl":"10.1016/j.jcjd.2025.11.003","url":null,"abstract":"<div><h3>Objectives</h3><div>The prevalence of type 2 diabetes (T2D) has increased substantially over the last decade among young populations living in Canada, with certain ethnic groups, such as African, Caribbean, and Black (ACB), being disproportionately affected. However, little is known about the suitability of the widely adopted T2D risk assessment tool, Canadian Diabetes Risk Questionnaire (CANRISK), for this population.</div></div><div><h3>Methods</h3><div>Two analytical samples of individuals aged 18 to 39 years were identified from 3 phases of CANRISK validation data collection: 1) young individuals from ACB ethnicities; and 2) all young individuals. Descriptive analyses were conducted for all predictors from the CANRISK and for prevalent dysglycemia (assessed by oral glucose tolerance test). The discriminatory ability of the CANRISK model was assessed by generating the area under the curve (AUC) and other model metrics. In addition, we assessed several cut points for the ACB subgroup to identify the optimal threshold.</div></div><div><h3>Results</h3><div>The prevalence of dysglycemia was higher among the ACB subgroup (n=715) than the overall young sample (n=3,960) (8.4% vs 7.7%). The CANRISK model performance was comparable for both groups, but slightly more accurate in the ACB subgroup (AUC 71.9% vs AUC 71.5%). The optimal cutoff for young ACB individuals was the same optimal cutoff of 19 as for the general Canadian youth population.</div></div><div><h3>Conclusions</h3><div>Our findings indicate that the CANRISK tool, with a modified cutoff point, is a suitable tool to identify T2D risk among young adults from ACB ethnicities. Future studies could explore the tool’s predictive ability via longitudinal studies to assess long-term diabetes risk.</div></div>","PeriodicalId":9565,"journal":{"name":"Canadian Journal of Diabetes","volume":"50 3","pages":"Pages 137-145.e1"},"PeriodicalIF":2.6,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145727602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0