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Radiotherapy for nasopharyngeal cancer: 2025 update 鼻咽癌放疗：2025年更新
IF 1.4 4区 医学
Cancer Radiotherapie Pub Date : 2025-11-01 Epub Date: 2025-08-21 DOI: 10.1016/j.canrad.2025.104711
Rafik Nebbache , Julian Biau , Florence Huguet , Séverine Racadot , Mailys de Meric de Bellefon , Laure Vieillevigne , Yoann Pointreau , Pierre Blanchard
{"title":"Radiotherapy for nasopharyngeal cancer: 2025 update","authors":"Rafik Nebbache ,&nbsp;Julian Biau ,&nbsp;Florence Huguet ,&nbsp;Séverine Racadot ,&nbsp;Mailys de Meric de Bellefon ,&nbsp;Laure Vieillevigne ,&nbsp;Yoann Pointreau ,&nbsp;Pierre Blanchard","doi":"10.1016/j.canrad.2025.104711","DOIUrl":"10.1016/j.canrad.2025.104711","url":null,"abstract":"<div><div>Nasopharyngeal cancers are rare in France but much more common in endemic regions such as Southeast Asia, North Africa, and Alaska. Radiotherapy remains the cornerstone of treatment, combined with chemotherapy for locally advanced cases. The technical aspects of radiotherapy are complex due to the proximity of numerous critical structures. Recent studies have explored the benefits of combining systemic therapies, such as immunotherapy, with radiotherapy, the advantage of de-escalating irradiated lymph node volumes to reduce toxicity while maintaining therapeutic efficacy, and the value of monitoring via Epstein-Barr virus circulating tumour DNA to improve patient follow-up. Here, we present the updated recommendations of the French society of radiation oncology (Société française de radiothérapie oncologique, SFRO) concerning the indications and technical modalities of radiotherapy in nasopharyngeal cancers.</div></div>","PeriodicalId":9504,"journal":{"name":"Cancer Radiotherapie","volume":"29 7","pages":"Article 104711"},"PeriodicalIF":1.4,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144880051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Management of cervical lymphadenopathies of unknown primary cancer 未知原发癌的宫颈淋巴结病的处理。
IF 1.4 4区 医学
Cancer Radiotherapie Pub Date : 2025-11-01 Epub Date: 2025-09-16 DOI: 10.1016/j.canrad.2025.104721
Xavier Musset , Idriss Troussier , Nolwenn Delaby , Pierre Blanchard , Yoann Pointreau , Sébastien Thureau
{"title":"Management of cervical lymphadenopathies of unknown primary cancer","authors":"Xavier Musset ,&nbsp;Idriss Troussier ,&nbsp;Nolwenn Delaby ,&nbsp;Pierre Blanchard ,&nbsp;Yoann Pointreau ,&nbsp;Sébastien Thureau","doi":"10.1016/j.canrad.2025.104721","DOIUrl":"10.1016/j.canrad.2025.104721","url":null,"abstract":"<div><div>Cervical lymphadenopathy of unknown primary tumour is a rare entity. In this situation, exhaustive diagnostic procedures are essential, including a comprehensive clinical examination, complete imaging, multiples biopsies and molecular testing. Localized disease cT0N1/N2a or low volumes N2b negative for Epstein-Barr virus can be treated either by surgery alone or unilateral neck radiation. For tumours N2b or above, either bilateral radiotherapy is proposed or chemoradiotherapy with cisplatin. Intensity-modulated radiotherapy is the standard technique of irradiation for the management of cervical lymphadenopathies of unknown primary origin. Dose regimens for postoperative or exclusive radiotherapy are detailed in this article, as well as the selection of prophylactic tumour and lymph node target volumes.</div></div>","PeriodicalId":9504,"journal":{"name":"Cancer Radiotherapie","volume":"29 7","pages":"Article 104721"},"PeriodicalIF":1.4,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145081802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rectal cancer radiotherapy: 2025 update 直肠癌放疗：2025年更新
IF 1.4 4区 医学
Cancer Radiotherapie Pub Date : 2025-11-01 Epub Date: 2025-09-10 DOI: 10.1016/j.canrad.2025.104722
Alice Blache , Marina Jolnerowski , Jérome Durand-Labrunie , Nicolas Meillan , Igor Bessières , Benjamin Schipman , Florence Huguet , Véronique Vendrely
{"title":"Rectal cancer radiotherapy: 2025 update","authors":"Alice Blache ,&nbsp;Marina Jolnerowski ,&nbsp;Jérome Durand-Labrunie ,&nbsp;Nicolas Meillan ,&nbsp;Igor Bessières ,&nbsp;Benjamin Schipman ,&nbsp;Florence Huguet ,&nbsp;Véronique Vendrely","doi":"10.1016/j.canrad.2025.104722","DOIUrl":"10.1016/j.canrad.2025.104722","url":null,"abstract":"<div><div>We present the updated recommendations of the Société française de radiothérapie oncologique (SFRO, the French society for oncological radiotherapy) for rectal cancer radiotherapy. The standard treatment for locally advanced rectal cancer consists in chemoradiotherapy followed by radical surgery with total mesorectal resection and adjuvant chemotherapy according to nodal status. Although this strategy efficiently reduced local recurrences rates below 5 % in expert centres, functional sequelae could not be avoided resulting in 20 to 30 % morbidity rates. The early introduction of neoadjuvant chemotherapy followed by chemoradiation has proven to be beneficial in recent trials, in terms of recurrence-free and metastasis-free survivals becoming the new standard treatment strategy. Complete pathological responses were obtained in 15 % of tumours treated by chemoradiotherapy, even reaching up to 30 % of tumours when neoadjuvant chemotherapy is associated to chemoradiotherapy. These good results question the relevance of systematic radical surgery in good responders. Personalized therapeutic strategies are now possible by improved imaging modalities with circumferential margin assessed by magnetic resonance imaging, by intensity-modulated radiotherapy and by refining surgical techniques, and contribute to morbidity reduction. Keeping the same objectives, ongoing trials are now evaluating therapeutic de-escalation strategies, in particular rectal preservation for good responders after neoadjuvant treatment or radiotherapy omission in selected cases.</div></div>","PeriodicalId":9504,"journal":{"name":"Cancer Radiotherapie","volume":"29 7","pages":"Article 104722"},"PeriodicalIF":1.4,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145026259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Radiotherapy of benign intracranial tumours: 2025 update 良性颅内肿瘤放疗：2025年更新
IF 1.4 4区 医学
Cancer Radiotherapie Pub Date : 2025-11-01 Epub Date: 2025-11-21 DOI: 10.1016/j.canrad.2025.104775
Kévin Quintin , Stéphanie Josset , Igor Latorzeff , Yoann Pointreau , Julian Biau , Delphine Antoni , Emmanuel Mesny
{"title":"Radiotherapy of benign intracranial tumours: 2025 update","authors":"Kévin Quintin ,&nbsp;Stéphanie Josset ,&nbsp;Igor Latorzeff ,&nbsp;Yoann Pointreau ,&nbsp;Julian Biau ,&nbsp;Delphine Antoni ,&nbsp;Emmanuel Mesny","doi":"10.1016/j.canrad.2025.104775","DOIUrl":"10.1016/j.canrad.2025.104775","url":null,"abstract":"<div><div>We present the updated recommendations of the Société française de radiothérapie oncologique (the French society for radiation oncology) on benign intracranial tumours. Most of them are meningiomas, vestibular schwannomas, pituitary adenomas, craniopharyngiomas, and glomus tumours. Some grow very slowly, and can be observed without specific treatment, especially if they are asymptomatic. Symptomatic or growing tumours are treated by surgery, which is the reference treatment. When surgery is not possible, due to the location of the lesion, or general conditions, radiotherapy can be applied, as it is if there is a postoperative growing residual tumour, or a local relapse. Indications must be discussed at a multidisciplinary panel, with precise evaluation of the benefit and risks of the treatments. The techniques to be used are the most modern ones, as multimodal imaging and image-guided radiation therapy. Stereotactic treatments, using fractionated or single (radiosurgery) doses depending on the size or the location of the tumours, are commonly realized, to avoid as much a possible the occurrence of late side effects.</div></div>","PeriodicalId":9504,"journal":{"name":"Cancer Radiotherapie","volume":"29 7","pages":"Article 104775"},"PeriodicalIF":1.4,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145575967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Radiotherapy and pregnancy: 2025 update 放疗与妊娠：2025年更新
IF 1.4 4区 医学
Cancer Radiotherapie Pub Date : 2025-11-01 Epub Date: 2025-09-10 DOI: 10.1016/j.canrad.2025.104719
Anna Gueiderikh , Morgan Michalet , Catherine Dejean , Ulrike Schick , Catherine Durdux , Alain Fourquet , Youlia Kirova
{"title":"Radiotherapy and pregnancy: 2025 update","authors":"Anna Gueiderikh ,&nbsp;Morgan Michalet ,&nbsp;Catherine Dejean ,&nbsp;Ulrike Schick ,&nbsp;Catherine Durdux ,&nbsp;Alain Fourquet ,&nbsp;Youlia Kirova","doi":"10.1016/j.canrad.2025.104719","DOIUrl":"10.1016/j.canrad.2025.104719","url":null,"abstract":"<div><div>We present the updated recommendations of the Société française de radiothérapie oncologique (SFRO, the French society for radiation oncology) on radiotherapy and pregnancy. The occurrence of cancer during pregnancy is a rare event (approximately 1 in 1000 pregnancies). The risks for the embryo or the foetus depend on the gestational age at the time of irradiation. The main risks are malformations with microcephaly and mental retardation. There is also a risk of radiation-induced cancer in the unborn child. In the case of only supradiaphragmatic irradiation, radiotherapy can be performed most often in pregnant women without risk to the foetus. On the other hand, in the case of an indication for subdiaphragmatic irradiation, therapeutic termination of the pregnancy should be proposed. In all cases, when radiotherapy is chosen, a phantom estimation of the dose delivered to the foetus, confirmed by in vivo measurement, is recommended. Conformational radiotherapy is the preferred technique because of the lower dose delivered to the foetus (except for tumour locations where other techniques such as intensity-modulated radiotherapy are recommended).</div></div>","PeriodicalId":9504,"journal":{"name":"Cancer Radiotherapie","volume":"29 7","pages":"Article 104719"},"PeriodicalIF":1.4,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145027041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Management of metallic implants in radiotherapy: 2025 update 放射治疗中金属植入物的管理：2025年更新
IF 1.4 4区 医学
Cancer Radiotherapie Pub Date : 2025-11-01 Epub Date: 2025-09-10 DOI: 10.1016/j.canrad.2025.104723
Adnan Shrebati , Clara Le Fèvre , Thomas Lacornerie , Georges Noël , Delphine Antoni , Pierre Loap , Youlia Kirova
{"title":"Management of metallic implants in radiotherapy: 2025 update","authors":"Adnan Shrebati ,&nbsp;Clara Le Fèvre ,&nbsp;Thomas Lacornerie ,&nbsp;Georges Noël ,&nbsp;Delphine Antoni ,&nbsp;Pierre Loap ,&nbsp;Youlia Kirova","doi":"10.1016/j.canrad.2025.104723","DOIUrl":"10.1016/j.canrad.2025.104723","url":null,"abstract":"<div><div>The number of patients receiving radiotherapy while having metallic implants is steadily increasing. These implants degrade the quality of computed tomography images used throughout the radiotherapy process, including delineation, dosimetry, and dose delivery. This document presents the updated recommendations from the Société française de radiothérapie oncologique (SFRO; i.e., the French society for radiation oncology), outlining the advantages and limitations of various existing and emerging methods designed to reduce the impact of metallic implants on radiotherapy quality and safety.</div></div>","PeriodicalId":9504,"journal":{"name":"Cancer Radiotherapie","volume":"29 7","pages":"Article 104723"},"PeriodicalIF":1.4,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145027039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Radiotherapy for patients with pacemakers and implantable cardioverter defibrillators: A review of the recommendations and practical application 心脏起搏器和植入式心律转复除颤器患者的放疗：建议和实际应用综述。
IF 1.4 4区 医学
Cancer Radiotherapie Pub Date : 2025-11-01 Epub Date: 2025-09-16 DOI: 10.1016/j.canrad.2025.104717
Sofiane Allali , Pierre Loap , Adnan Shrebati , Thomas Lacornerie , Youlia Kirova , Frédéric Sebag , Kim-I. Cao
{"title":"Radiotherapy for patients with pacemakers and implantable cardioverter defibrillators: A review of the recommendations and practical application","authors":"Sofiane Allali ,&nbsp;Pierre Loap ,&nbsp;Adnan Shrebati ,&nbsp;Thomas Lacornerie ,&nbsp;Youlia Kirova ,&nbsp;Frédéric Sebag ,&nbsp;Kim-I. Cao","doi":"10.1016/j.canrad.2025.104717","DOIUrl":"10.1016/j.canrad.2025.104717","url":null,"abstract":"<div><div>Radiotherapy is a common treatment in the oncological management of patients. Each year, approximately 98,000 patients receive an implanted cardiac device. The integrity and safety of this device must be considered during radiotherapy. Recommendations established by scientific societies have been implemented, particularly to assess the risk of damage to pacemakers or defibrillators based on the dependency on the implanted cardiac device, the energy, and the type of irradiation used. In this article, we review the main recommendations, establish a procedure, and provide guidelines for the management and monitoring of these patients during radiotherapy. The aim is to offer a clear and practical framework for the management of implanted cardiac devices within a radiotherapy department.</div></div>","PeriodicalId":9504,"journal":{"name":"Cancer Radiotherapie","volume":"29 7","pages":"Article 104717"},"PeriodicalIF":1.4,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145081829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reirradiation of lung, breast and bone tumours, suggestions from the Recommendations Commission of the Société française de radiothérapie oncologique 肺、乳腺和骨肿瘤的再照射，来自放射肿瘤学会建议委员会的建议
IF 1.4 4区 医学
Cancer Radiotherapie Pub Date : 2025-11-01 Epub Date: 2025-11-28 DOI: 10.1016/j.canrad.2025.104780
Yuedan Zhou , Alexandre Escande , Arnaud Beddok , Cyrus Chargari , Marie-Pierre Sunyach , Myriam Ayadi , Jonathan Khalifa , Delphine Antoni , Kim Cao , David Pasquier , Jean-Michel Hannoun-Lévi , Martin Langé , Jean-Christophe Faivre , Sébastien Thureau , Stéphane Supiot
{"title":"Reirradiation of lung, breast and bone tumours, suggestions from the Recommendations Commission of the Société française de radiothérapie oncologique","authors":"Yuedan Zhou ,&nbsp;Alexandre Escande ,&nbsp;Arnaud Beddok ,&nbsp;Cyrus Chargari ,&nbsp;Marie-Pierre Sunyach ,&nbsp;Myriam Ayadi ,&nbsp;Jonathan Khalifa ,&nbsp;Delphine Antoni ,&nbsp;Kim Cao ,&nbsp;David Pasquier ,&nbsp;Jean-Michel Hannoun-Lévi ,&nbsp;Martin Langé ,&nbsp;Jean-Christophe Faivre ,&nbsp;Sébastien Thureau ,&nbsp;Stéphane Supiot","doi":"10.1016/j.canrad.2025.104780","DOIUrl":"10.1016/j.canrad.2025.104780","url":null,"abstract":"<div><div>The process of reirradiation in oncology presents a distinctive set of challenges, wherein clinical decision-making is predicated on a delicate balancing act between the efficacy of the treatment and the risk of severe toxicity. Despite the paucity of randomised and prospective data, there is an increasing number of data encouraging its consideration for patients with local or metastatic recurrence. While awaiting dedicated guidance from international scientific societies, this publication is based on multicentre reflections of the “Recommendations Commission” of the Société française de radiothérapie oncologique (the French society for radiation oncology). It addresses key questions related to reirradiation, with a particular focus on lung, breast and bone tumours.</div></div>","PeriodicalId":9504,"journal":{"name":"Cancer Radiotherapie","volume":"29 7","pages":"Article 104780"},"PeriodicalIF":1.4,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145614827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Radiotherapy for haematological malignancies: Current best practices and advancements 恶性血液病的放射治疗：目前的最佳实践和进展。
IF 1.4 4区 医学
Cancer Radiotherapie Pub Date : 2025-11-01 Epub Date: 2025-10-16 DOI: 10.1016/j.canrad.2025.104754
Fatima Zahra Bellefkih , Benjamin Vandendorpe , Kamel Debbi , Gabriele Coraggio , Nhu Hanh To , Luc Simon , Luc Ollivier , Youlia Kirova , Yazid Belkacémi
{"title":"Radiotherapy for haematological malignancies: Current best practices and advancements","authors":"Fatima Zahra Bellefkih ,&nbsp;Benjamin Vandendorpe ,&nbsp;Kamel Debbi ,&nbsp;Gabriele Coraggio ,&nbsp;Nhu Hanh To ,&nbsp;Luc Simon ,&nbsp;Luc Ollivier ,&nbsp;Youlia Kirova ,&nbsp;Yazid Belkacémi","doi":"10.1016/j.canrad.2025.104754","DOIUrl":"10.1016/j.canrad.2025.104754","url":null,"abstract":"<div><div>Haematological malignancies include a broad spectrum of diseases. The substantial progress made in systemic treatment over the last 20<!--> <!-->years is reshaping the role of radiotherapy. Recent technological progress in imaging and radiotherapy has led to significant refinements in targets definition, sparing of organ at risk to reduce toxicity, thus ensuring that radiotherapy remains the cornerstone for several indications. We present the recommendations of the Société française de radiothérapie oncologique for radiotherapy of haematological malignancies, which continues to evolve rapidly in terms of therapeutic strategy.</div></div>","PeriodicalId":9504,"journal":{"name":"Cancer Radiotherapie","volume":"29 7","pages":"Article 104754"},"PeriodicalIF":1.4,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145314249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
External irradiation treatment process: 2025 update 外照射治疗工艺：2025年更新
IF 1.4 4区 医学
Cancer Radiotherapie Pub Date : 2025-11-01 Epub Date: 2025-11-28 DOI: 10.1016/j.canrad.2025.104773
Quentin Duhoux , Vincent Marchesi , Fabrice Lorchel , David Azria , Ulrike Schick , Isabelle Barillot
{"title":"External irradiation treatment process: 2025 update","authors":"Quentin Duhoux ,&nbsp;Vincent Marchesi ,&nbsp;Fabrice Lorchel ,&nbsp;David Azria ,&nbsp;Ulrike Schick ,&nbsp;Isabelle Barillot","doi":"10.1016/j.canrad.2025.104773","DOIUrl":"10.1016/j.canrad.2025.104773","url":null,"abstract":"<div><div>The purpose of this article is to describe the external irradiation process and updated recommendations of the Société française de radiothérapie oncologique for patient follow-up.</div></div>","PeriodicalId":9504,"journal":{"name":"Cancer Radiotherapie","volume":"29 7","pages":"Article 104773"},"PeriodicalIF":1.4,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145614825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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