Bulletin of the Institute for Chemical Research, Kyoto University最新文献

{"title":"Solvent Extraction of Beryllium as Acetylacetonate","authors":"M. Tabushi","doi":"10.1246/NIKKASHI1948.80.2_159","DOIUrl":"https://doi.org/10.1246/NIKKASHI1948.80.2_159","url":null,"abstract":"アセチルアセトン塩としてベリリウムをクロロホルムで抽出する際の条件につき検討した。抽出率などをもとめるに際しベリリウムの定量をエリオクロムシァニンR法によって行うため,ベリリウムの比色定量条件についても検討を加えた。ベリリウムはpH6～9の溶液からアセチルアセトン塩としてクロロホルムに完全に抽出せられ,エリオクロムシァニンRで比色定量できる。他金属と分離するためエチレンジァミンテトラ酢酸を加えて隠蔽すると,ベリリウムの抽出率は低下し,塩類の添加で抽出率を上げることができるが,完全に抽出することは困難である。核分裂生成物とベリリウムの分離をエチレンジアミンテトラ酢酸の存在で行ったが抽出率は約95%,抽出したベリリウム申には放射能はほとんど認められず,分離が完全であることがわかった。","PeriodicalId":9502,"journal":{"name":"Bulletin of the Institute for Chemical Research, Kyoto University","volume":"102 1","pages":"156-162"},"PeriodicalIF":0.0,"publicationDate":"1958-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91458922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Studies on the Antimetabolites of Amino Acids. (VIII) : Formation of Arginosuccinic Acid and Canavanosuccinic : Acid in Microorganisms","authors":"Tomoji Suzuki, S. Muraoka, T. Makino","doi":"10.1248/YAKUSHI1947.77.3_282","DOIUrl":"https://doi.org/10.1248/YAKUSHI1947.77.3_282","url":null,"abstract":"S Studies on the Antimetabolites of Amino Acids. (VIII) Formation of Arginosuccinic Acid and Canavanosuccinic Acid in Microorganisms Tomoji SUZUKI, Saburo MUPAOKA and Teruo MAKINO (Suzuki Laboratory) Journal of the Pharmaceutical Society of Japan (Yakugaku Zasshi), 77, 282 (1957) Acetone-dried cells of Escherichia coli and Lactobacillus arabinosus were prepared and the formation of arginosuccinic acid (ASA) and canavanosuccinic acid (CSA) from arginine or canavanine and fumarate was followed by paper electrophoresis and paper chromatography. ASA was found to be formed by the parent strain of E. coli but it was not detected with its arginine-requiring mutant (cannot be compensated with ornithine or citrulline). Even with the parent strain, its culture in a medium containing arginine causes disappearance of arginosuccinase activity and ASA formation does not take place. The formation of CSA was identical with the case of ASA. With Lact. arabinosus ASA was formed from citrulline and aspartic acid, as well as from arginine and fumarate. CSA itself inhibits proliferation of Lact. arabinosus and this inhibition is easily recoverd with arginine. Considerations were made on the action mechanism of canavanine from these experimental results. Studies on the Antimetabolites of Amino Acids. (IX) Biological Activity of Aspartic Acid Monoand Dihydrazide Tomoji SUZUKI and Fumihiko TANAKA (Suzuki Laboratory) Journal of the Pharmaceutical Society of Japan (Yakugaku Zasshi), 77, 1218 (1957) As partic acid monoand dihydrazides, and 3-hydroxyaspartic acid were synthesized and their action in inhibiting the growth of Leuconostoc mesenteroides P-60 and Escherichia coli No. 1 was examined. In the presence of aspartic acid, growth of Leuc. mesenteroides was completely inhibited by 100 r/cc. of monohydrazide, 500 r/cc. of 3-hydroxyaspartic acid, and 2000 r/cc. of dihydrazide. So far as Leuc. mesenteroides is concened, therefore, the growthinhibitory action of monohydrazide is stronger than that of dihydrazide. On the contrary, the growth of E. coli No. 1, which requires no aspartic acid for growth, was more strongly inhibited by the dihydrazide, the effective concentration for 50 9 inhibition being 55 r/cc. of the monohydrazide and 33 r/cc. of (118)","PeriodicalId":9502,"journal":{"name":"Bulletin of the Institute for Chemical Research, Kyoto University","volume":"26 1","pages":"118-118"},"PeriodicalIF":0.0,"publicationDate":"1958-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84890447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Studies on the Second-Order Transition Temperature of Polyvinyl Alcohol. (II) : Influence of Rate of Heating and Degrees of P olymerization on the Second-Order Transition Temperature of Polyvinyl Alcohol","authors":"Y. Sone, I. Sakurada","doi":"10.1295/KORON1944.14.574","DOIUrl":"https://doi.org/10.1295/KORON1944.14.574","url":null,"abstract":"ポリビニルアルコール (PVA) フィラメントの風乾物およびPVA皮膜の絶乾物を試料として, 2次転移温度に及ぼす加熱速度の影響を検討した。風乾フィラメントについては加熱速度を0.066℃/minから1.0℃/minまで変化したが2次転移温度は66℃ である。また絶乾皮膜については加熱速度を0.2℃/minおよび20℃/minにして実験したが, 2次転移温度は73℃ であって, いずれの際にも加熱速度の影響は認められない。また平均重合度140, 441, 1071, 3820, 46355個の完全ケン化分別PVAからつくった皮膜の絶乾物について, 2次転移温度を測定したが, いずれの重合度の試料についても72±1℃ であって, 平均重合度の影響もまた認められない。","PeriodicalId":9502,"journal":{"name":"Bulletin of the Institute for Chemical Research, Kyoto University","volume":"28 1","pages":"107-108"},"PeriodicalIF":0.0,"publicationDate":"1958-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87266648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis of Acetic Acid from Met h anol and Carbon Monoxide under High Pressure","authors":"Y. Takezaki, Nobuya Okamoto, T. Miyazaki, Sachio Yuasa","doi":"10.1246/NIKKASHI1898.60.1038","DOIUrl":"https://doi.org/10.1246/NIKKASHI1898.60.1038","url":null,"abstract":"高温高圧下において一酸化炭素とCH3OH・BF3とより酢酸を合成する実験を行い,その結果CH3OH・BF3はCH3OCH3・BF3およびH2O・BF3を生じ,これらと平衡を保ちつつ一酸化炭素と反応することを明らかにした。酢酸の生成速度はCH3OH・BF3の平衡濃度および一酸化炭素のフガシテイーの1次に比例し,その速度定数は200℃においてk=1.7×10-5 atm-1・min-1であり,活性化エネルギーは約15kcal/molである。反応温度が210℃以上となるとタール状物質生成の副反応のために酢酸の最終収率は低下する。酢酸合成の条件としては,H2O・BF3とCH3OH・BF3のモル比1.5,反応温度200℃,一酸化炭素圧力1000atmが適当であり,この条件の場合反応時間2時間で酢酸収率92mol%をえた。","PeriodicalId":9502,"journal":{"name":"Bulletin of the Institute for Chemical Research, Kyoto University","volume":"10 1","pages":"105-105"},"PeriodicalIF":0.0,"publicationDate":"1958-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87689305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microbiological Assay of Vitamins and Amino : Acids by One-dimentional Diffusion Method","authors":"Tomoji Suzuki, F. Tanaka","doi":"10.1248/YAKUSHI1947.77.10_1159","DOIUrl":"https://doi.org/10.1248/YAKUSHI1947.77.10_1159","url":null,"abstract":"S On the Transglycosidation relating to Riboflavinn by Escherichia coli. (I) • Formation of Riboflavinyl Glucoside Hideo KATAGIRI, Hideaki YAMADA and Kazutami IMAI (Katagiri Laboratory) The Journal of Vitaminology, 3, 264 (1957) Riboflavinyl glucoside has been isolated from reaction mixture composed of riboflavin, maltose and the cell suspension of Esherichia coli. The suitable conditions and the effects of several substances on the formation of riboflavinyl glucoside were studied, and it is ascertained that riboflavin plays the role of specific acceptor of transglycosidation, and concluded that the interaction of the enzyme on isoalloxazine ring of riboflavin molecule would take place in the first step of the reaction. Thus the authors suggest that riboflavin reveals a new biochemical significance in carbohydrate metabolism. Microbiological Assay of Vitamins and Amino Acids by One-dimentional Diffusion Method Tomoji SUZUKI and Fumihiko TANAKA (Suzuki Laboratory) Journal of the Pharmaceutical Society of Japan (Yakugaku Zasshi), 77, 1159 (1957) We designed the one-dimentional diffusion method for microbiological assay of vitamins and amino acids. The agar synthetic medium containing triphenyltetrazoliumchloride (TTC) (50mg/100cc. of medium) and test organisms for example, Lactobacillus arabinosus 17-5 is poured into the test tube which is 75 mm in hight and 5 mm in diameter. After the medium solidified, about 0.1 ml of sample were over it. Following incubation about 12 hours, red zone of reduced TTC were observed. This red zone is proportional to logarithms of concentration of amino acids and vitamins. Using Lactobacillus arabinosus 175, the assay range is as following : biotin 1-100 mr/cc., pantothenic acid and nicotinic acid 0.1-100r/cc., DL-phenylalanine and DL-methionine 15-1000r/cc., L-leucine 60---1000r/cc. This method is distinguished with large range of determination and small amount of medium, still more convenient for routine assay (117 )","PeriodicalId":9502,"journal":{"name":"Bulletin of the Institute for Chemical Research, Kyoto University","volume":"57 1","pages":"117-118"},"PeriodicalIF":0.0,"publicationDate":"1958-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75304196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Dimorphism and t h e Crystal Habits of Copper-Oxinate Precipitates","authors":"E. Suito, Eiji Sekido","doi":"10.2183/PJAB1945.33.196","DOIUrl":"https://doi.org/10.2183/PJAB1945.33.196","url":null,"abstract":"","PeriodicalId":9502,"journal":{"name":"Bulletin of the Institute for Chemical Research, Kyoto University","volume":"100 1","pages":"153-154"},"PeriodicalIF":0.0,"publicationDate":"1958-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77670805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Specimen Preparation Technique for the Crystal Habit","authors":"E. Suito, Natsu Uyda, Kazuyoshi Takiya","doi":"10.1093/OXFORDJOURNALS.JMICRO.A051232","DOIUrl":"https://doi.org/10.1093/OXFORDJOURNALS.JMICRO.A051232","url":null,"abstract":"","PeriodicalId":9502,"journal":{"name":"Bulletin of the Institute for Chemical Research, Kyoto University","volume":"19 1","pages":"150-152"},"PeriodicalIF":0.0,"publicationDate":"1958-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83695001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis of an Anion-Excha n g e Resin from Methylvinylketone","authors":"H. Suda, Susumu Inoue, R. Oda","doi":"10.1246/nikkashi1898.60.508","DOIUrl":"https://doi.org/10.1246/nikkashi1898.60.508","url":null,"abstract":"S and the average polymerization degree is 19. The polymer is soluble in the most solvents, but insoluble in petroleum ether and water. It is easily decomposed by acid, and yields acetaldehyde. This fact points out that the polymer is a polyacetal. Synthesis of an Anion-Exchange Resin from Methylvinylketone Hiroshi SUDA, Susumu INouE and Ryohei ODA (Oda Laboratory) J. Chem. Soc. Japan, hid. Chem. Sec. (Ka gyo Kagaku Zasshi ), 60, 508 (1957) Polymethylvinylketone has the active methylene and methyl groups adjacent to its carbonyl groups. Paying attention to these groups, the authors attempted the synthesis of an anion-exchange resin by the Mannich reaction on methylvinylketone-divinylbenzene copolymer. The starting copolymer was prepared by the bulk polymerization of methyl vinyl ketone and divinylbenzene (molar ratio 95 : 5) using azobisisobutyronitrile as initiator. The above polymer was suspended in dioxane, formaldehyde and dimethylamine were added, and the mixture was refluxed for ca. 25 hrs. The structure of the obtained resin could be written as follows. —CH—CH2---CH --CH3—CH—CH2 ICH2 —N(CI I;,)_ CO °\" COI III ! ; CHsO I NH(CIIs)3---C—Ci-I2—CH----CH_—CH-CH, _._ CII3 CH31 CO // CO --CH--CH_--1 I 11 1 CH3 / CH2 --CH— CH2---CH3—N(CH8) 2 The nitrogen content of this resin was found as 8.24%, i.e., the degree of aminomethylation was 62%. The ionexchage capacity was measured by the usual method. It was 5.66 m. eq./g. of dried resin, while the theoretical value calculated from the nitrogen content was 5.88 in. eq./g. In order to quarternize the amino group, the aminated resin was treated with dimethyl sulfate or methyl iodide in dioxane for ca. 12 hrs. at 40-50°C and then allowed to stand room temperature for 50 hrs. Only 23% of total amino groups was quarternized. The ability of decomposing neutral salt was 1.15 m. eq./g. The difficulty in quarternization may be due to the deamination and intraor inter-molecular recombination.","PeriodicalId":9502,"journal":{"name":"Bulletin of the Institute for Chemical Research, Kyoto University","volume":"10 1","pages":"160-160"},"PeriodicalIF":0.0,"publicationDate":"1958-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85374553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reaction of n-Hexyl Bromide with Potassium Fluoride in Several Glycols","authors":"H. Kitano, K. Fukui","doi":"10.1246/NIKKASHI1898.60.272","DOIUrl":"https://doi.org/10.1246/NIKKASHI1898.60.272","url":null,"abstract":"","PeriodicalId":9502,"journal":{"name":"Bulletin of the Institute for Chemical Research, Kyoto University","volume":"198 1","pages":"155-155"},"PeriodicalIF":0.0,"publicationDate":"1958-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80009003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Resolution of (±)-trans-3-(trans-2'-Carboxypropenyl)-2,2-dimethylcyclopropane-1-carboxylic Acid","authors":"Y. Inouye, M. Ohno","doi":"10.1271/BBB1924.21.265","DOIUrl":"https://doi.org/10.1271/BBB1924.21.265","url":null,"abstract":"Studies on Synthetic Pyrethroid. (XI) Another Evidence for the trans-Configuration of a,o-Dimethylsorbic Acid Yuzo INOUYE, Toshio SUGITA and Minoru OuNo (Ohno Laboratory) Bull. Agr. Chem. Soc.Japan, 21, 222 (1957) (English edition) Bolyu-Kagaku, 22, 227 (1957) (Japanese edition) Methyl a,o-dimethylsorbate(I) gave methyl r,o-epoxy-a,o-dimethyl-Ja-hexenoate (II), bp. 91-2°/6 mm., nl' 1.4672, by the epoxydation with perbenzoic acid. II was easily effected by treatment with dil. sulphuric acid and gave r, o-dihydroxy-ad-dimethyl-da-hexenoate (III), mp. 50-1°. Lead tetracetate cleaved the glycolic carbon-carbon linkage of III and gave j3-monomethyl mesaconaldehydate (IV), bp. 76-8°/12mm., n; 1.4680. 3, 4-Dinitrophenylhydrazone of IV, mp. 204-4.5° IV was then oxidized with peracetic acid to j3-monomethyl mesaconate (V), mp. 82-3°, diamide, mp. 117° these were completely consistent with the literature. Cold saponification of V gave mesaconic acid (VI) mp. 202-3°, not depressed by the mixed mp. comparison with an authentic specimen. Di-p-phenylphenacyl ester of VI, mp. 204-5°. Since the oxidation sequence involves no process likely to invert the geometrical configuration of double bond, the retention of the configuration in the parent compound can reasonably be concluded. Thus, the final formation of mesaconic acid of the well-established trans-configuration unambiguously shows the transcofiguration of the a, (3-double bond of the parent methyl a, 8-dimethylsorbate (I). Direct peroxidation of a,o-dimethylsorbic acid also gave mesaconic acid in an inferior yield. Resolution of (± )-trans-3-(trans-2'-Carboxypropenyl)-2, 2-dimethylcyclopropane-l-carboxylic Acid Yuzo INOUYE and Minoru OxNo (Ohno Laboratory) Bull. Agr. Chem. Soc. Japan, 21, 265(1957) (English edition) The partial resolution of (±)-trans-3-(trans-2'-carboxypropenyl)-2, 2-dimethylcyclopropane-1-carboxylic acid by means of a synthetic optical active (—)-aphenylethylamine to give the dextrorotatory acid, which was completely indentical with the naturally derived acid, has already been described by the authors, and here, the complete resolution was achieved by obtaining the enantiomorphic laevorotatory acid with the results summarized below (rotations in ethanol). m.p. CaTi (+)-acid 163-4° (±)-acid 206-8° 0 (— )-acid 163-4° — 70.5° (158)","PeriodicalId":9502,"journal":{"name":"Bulletin of the Institute for Chemical Research, Kyoto University","volume":"23 1","pages":"158-158"},"PeriodicalIF":0.0,"publicationDate":"1956-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81572878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}