Cardiology journal最新文献

{"title":"Randomized comparison of 9-month stent strut coverage of biolimus and everolimus drug-eluting stents assessed by optical coherence tomography in patients with ST-segment elevation myocardial infarction. Long-term (5-years) clinical follow-up (ROBUST trial).","authors":"Martin Jakl, Pavel Cervinka, Jan Kanovsky, Petr Kala, Martin Poloczek, Michaela Cervinkova, Hiram G Bezerra, Zdenek Valenta, Marco Aurelio Costa","doi":"10.5603/CJ.a2023.0013","DOIUrl":"10.5603/CJ.a2023.0013","url":null,"abstract":"<p><strong>Background: </strong>The aim of the study was to compare healing (assessed by optical coherence tomography [OCT]) of biolimus A9 (BES) and everolimus drug-eluting stents (EES) at 9-month follow-up in patients with ST-segment elevation myocardial infarction (STEMI) treated by primary percutaneous coronary intervention (pPCI). Nine-month clinical and angiographic data were also compared in both groups as well as clinical data at 5 years of follow-up.</p><p><strong>Methods: </strong>A total of 201 patients with STEMI were enrolled in the study and randomized either to pPCI with BES or EES implantation. All patients were scheduled for 9 months of angiographic and OCT follow-up.</p><p><strong>Results: </strong>The rate of major adverse cardiovascular events (MACE) was comparable at 9 months in both groups (5% in BES vs. 6% in the EES group; p = 0.87). Angiographic data were also comparable between both groups. The main finding at 9-month OCT analysis was the greatly reduced extent of mean neointimal area at the cost of a higher proportion of uncovered struts in the BES group (1.3 mm² vs. 0.9 mm²; p = 0.0001 and 15.9% vs. 7.0%; p = 0.0001, respectively). At 5 years of clinical follow-up the rate of MACE was comparable between both groups (16.8% vs. 14.0%, p = 0.74).</p><p><strong>Conclusions: </strong>The study demonstrates a very low rate of MACE and good 9-month stent strut coverage of second-generation BES and EES in patients with STEMI. BES showed greatly reduced extent of mean neointimal hyperplasia area at the cost of a higher proportion of uncovered struts when compared to EES. The rate of MACE was low and comparable in both groups at 5 years.</p>","PeriodicalId":9492,"journal":{"name":"Cardiology journal","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2023-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10713210/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9153298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A novel polymer-free everolimus-eluting stent with a nitrogen-doped titanium dioxide film inhibits restenosis and thrombosis in a swine coronary model.","authors":"Dae Young Hyun, Xiongyi Han, Dae Sung Park, Munki Kim, Jun Kyu Park, Kyung Hoon Cho, Doo Sun Sim, Young Joon Hong, Youngkeun Ahn, Myung Ho Jeong","doi":"10.5603/CJ.a2023.0006","DOIUrl":"10.5603/CJ.a2023.0006","url":null,"abstract":"<p><strong>Background: </strong>Short-term outcomes regarding the safety and efficacy of a polymer-free everolimus-eluting stent (EES) with a nitrogen-doped titanium dioxide (N-TiO₂) film in a swine coronary model have been reported. However, the long-term results of the use of this type of stent have not yet been evaluated or compared to those of other polymer-free coronary stents. Therefore, this study aimed to determine the mid- to long-term safety and efficacy of a polymer-free EES with an N-TiO₂ film in a swine coronary model.</p><p><strong>Methods: </strong>Polymer-free EES with N-TiO₂ films (n = 30) and polymer-free sirolimus-eluting stents (SES; n = 30) were implanted in 30 pigs. Quantitative coronary analysis and optical coherence tomography were conducted immediately and at 1 (quantitative coronary analysis only), 3, and 6 months after stenting. Histopathologic examinations were performed at 1, 3, and 6 months after stenting.</p><p><strong>Results: </strong>The polymer-free EES group had a lower percentage of neointimal growth than the polymer-free SES group at 3 months (22.5% ± 11.4% vs. 32.1% ± 12.3%; p < 0.001). The polymer-free EES group had a lower fibrin score than the polymer-free SES group at 1 month (1.9 ± 0.45 vs. 2.5 ± 0.54; p = 0.001). The re-endothelialization rates were similar between groups. The polymer-free EES group had a lower percentage of the area of stenosis than the polymer-free SES group throughout the follow-up period.</p><p><strong>Conclusions: </strong>The novel polymer-free EES with an N-TiO₂ film has superior safety and efficacy than the polymer-free SES at the 6-month follow-up in a swine model.</p>","PeriodicalId":9492,"journal":{"name":"Cardiology journal","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2023-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10713211/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10716836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Atrial fibrillatory wave amplitude revisited: A predictor of recurrence after catheter ablation independent of the degree of left atrial structural remodeling.","authors":"Shiro Ishihara, Mitsunori Maruyama, Tsuyoshi Nohara, Wataru Shimizu, Kuniya Asai","doi":"10.5603/CJ.a2022.0120","DOIUrl":"10.5603/CJ.a2022.0120","url":null,"abstract":"<p><strong>Background: </strong>The fibrillatory wave amplitude (FWA) during atrial fibrillation (AF) is thought to reflect structural atrial remodeling, but it remains unclear what determines the FWA.</p><p><strong>Methods: </strong>114 consecutive patients were prospectively studied who underwent catheter ablation of AF. The mean FWA was computed by automated surface ECG analyses. The extent of the left atrial (LA) voltage-defined atrial fibrosis and conduction properties were estimated by a three-dimensional high-density electroanatomical mapping system. The LA size was evaluated by transthoracic echocardiography. The study patients were divided into 2 groups according to an FWA in lead V1 above the median value of 46 µV (high FWA group, n=57) or below 46 µV (low FWA group, n=57).</p><p><strong>Results: </strong>There were no differences in the age, gender, CHADS2 score, prevalence of paroxysmal AF, medications, ablation strategy, and LA volume index between the two groups. The LA low voltage areas in the low FWA group were not different from those in the high FWA group. The total LA activation time and local LA conduction velocity did not differ between the two groups. During a median follow-up of 710 days, the recurrence rate after ablation was significantly higher in patients with a low FWA than a high FWA (log-rank P=0.02). In a multivariate analysis, non-paroxysmal AF, the LA volume index, and FWA were independent predictors of recurrence after　ablation.</p><p><strong>Conclusions: </strong>The FWA was not correlated with the markers of atrial structural remodeling. Nevertheless, the FWA could still provide information for predicting the clinical outcome after AF ablation.</p>","PeriodicalId":9492,"journal":{"name":"Cardiology journal","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2023-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10713214/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10826914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Echocardiographic markers of cardiac amyloidosis in patients with heart failure and left ventricular hypertrophy.","authors":"Jorge Melero Polo,&nbsp;Ana Roteta Unceta-Barrenechea,&nbsp;Pablo Revilla Martí,&nbsp;Raquel Pérez-Palacios,&nbsp;Anyuli Gracia Gutiérrez,&nbsp;Esperanza Bueno Juana,&nbsp;Alejandro Andrés Gracia,&nbsp;Saida Atienza Ayala,&nbsp;Miguel Ángel Aibar Arregui","doi":"10.5603/CJ.a2021.0085","DOIUrl":"https://doi.org/10.5603/CJ.a2021.0085","url":null,"abstract":"<p><strong>Background: </strong>Cardiac amyloidosis (CA), following a non-invasive diagnosis, constitutes an increasingly prevalent heart failure (HF) etiology. This study aims to determine which echocardiography findings help to diagnose CA in patients with left ventricular hypertrophy (LVH) admitted for decompensated HF.</p><p><strong>Methods: </strong>The present study is a retrospective observational study on a cohort of 85 LVH patients admitted for HF decompensation, in which 99mTc-DPD scanning was performed to rule out transthyretin CA. The echocardiographic findings obtained were compared between CA and non-CA groups.</p><p><strong>Results: </strong>From a total number of 85 patients, 49 (57.6%) met the CA criteria and 36 (42.3%) were ruled out for the disease. Interventricular septum thickness (16 ± 3 mm vs. 14 ± 3 mm), left ventricular posterior wall thickness (14 ± 3 mm vs. 11 ± 2 mm), left ventricular mass (259 ± 76 g vs. 224 ± 53 g), left ventricular end-diastolic diameter (48 ± 7 mm vs. 53 ± 6 mm), left ventricular end-diastolic indexed volume (51 ± 18 cm3/m2 vs. 59 ± 16 cm3/m2), tricuspid annular plane systolic excursion (16 ± 5 mm vs. 20 ± 4 mm), right atrial area (27.4 ± 8.4 cm2 vs. 22.2 ± 5.7 cm2) and strain relative apical sparing (2.2 ± 0.9 vs. 1.03 ± 0.4; p = 0.04) were significantly associated with the diagnosis of CA.</p><p><strong>Conclusions: </strong>In patients with LVH admitted for HF decompensation, there are several echocardiographic features (LVH, reduced left ventricular cavity size, strain relative apical sparing, right atrial dilation, and altered right ventricular function) that are associated with the diagnosis of cardiac amyloidosis.</p>","PeriodicalId":9492,"journal":{"name":"Cardiology journal","volume":"30 2","pages":"266-275"},"PeriodicalIF":2.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/34/52/cardj-30-2-266.PMC10129250.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9400083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hydropneumopericardium after pericardiocentesis in a transplant patient.","authors":"Arnaud Planchat,&nbsp;Florian Stierlin,&nbsp;Alix Juillet de Saint-Lager-Lucas,&nbsp;Andrea Peloso,&nbsp;Sarah Mauler-Wittwer,&nbsp;Stephane Noble","doi":"10.5603/CJ.2023.0024","DOIUrl":"https://doi.org/10.5603/CJ.2023.0024","url":null,"abstract":"","PeriodicalId":9492,"journal":{"name":"Cardiology journal","volume":"30 2","pages":"335-336"},"PeriodicalIF":2.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ee/d3/cardj-30-2-335.PMC10129258.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9403596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impella-rota-shock percutaneous coronary intervention: Three weapons, one last remaining vessel.","authors":"Alexandra Briosa,&nbsp;Ana Rita Pereira,&nbsp;Mariana Martinho,&nbsp;Rita Calé,&nbsp;Hélder Pereira","doi":"10.5603/CJ.2023.0011","DOIUrl":"https://doi.org/10.5603/CJ.2023.0011","url":null,"abstract":",","PeriodicalId":9492,"journal":{"name":"Cardiology journal","volume":"30 1","pages":"159-160"},"PeriodicalIF":2.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d4/17/cardj-30-1-159.PMC9987545.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9407503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early and late asystole after loop recorder implantation: Misdiagnoses and unexpected diagnostic opportunities.","authors":"Giulia Domenichini,&nbsp;Patrice Carroz,&nbsp;Etienne Pruvot,&nbsp;Patrizio Pascale","doi":"10.5603/CJ.2023.0012","DOIUrl":"https://doi.org/10.5603/CJ.2023.0012","url":null,"abstract":"An 84-year-old (case 1) and a 79-year-old patient (case 2) were implanted with a Medtronic Reveal LINQ™ in the context of an unexplained syncope of suspected arrhythmic origin.","PeriodicalId":9492,"journal":{"name":"Cardiology journal","volume":"30 1","pages":"161-162"},"PeriodicalIF":2.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e9/72/cardj-30-1-161.PMC9987536.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9407507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inside Cardiology Journal: After Journal Citation Reports 2022 have been published.","authors":"Łukasz Stolarczyk,&nbsp;Natasza Gilis-Malinowska,&nbsp;Milosz J Jaguszewski,&nbsp;Juan Luis Gutiérrez-Chico","doi":"10.5603/cj.97141","DOIUrl":"10.5603/cj.97141","url":null,"abstract":"","PeriodicalId":9492,"journal":{"name":"Cardiology journal","volume":"30 4","pages":"499-501"},"PeriodicalIF":2.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/56/3d/cardj-30-4-499.PMC10508082.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10239588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ticagrelor effectively inhibits platelet aggregation in comatose survivors of cardiac arrest undergoing primary percutaneous coronary intervention treated with mild therapeutic hypothermia.","authors":"Marek T Tomala,&nbsp;Aleksander Trąbka-Zawicki,&nbsp;Andrzej Machnik,&nbsp;Bartłomiej A Nawrotek,&nbsp;Wojciech Zajdel,&nbsp;Ewa Ł Stępień,&nbsp;Jacek Legutko,&nbsp;Krzysztof Żmudka","doi":"10.5603/CJ.a2021.0064","DOIUrl":"10.5603/CJ.a2021.0064","url":null,"abstract":"<p><strong>Background: </strong>Mild therapeutic hypothermia (MTH) is believed to reduce the effectiveness of antiplatelet drugs. Effective dual-antiplatelet therapy after percutaneous coronary intervention (PCI) is mandatory to avoid acute stent thrombosis. The effectiveness of ticagrelor in MTH-treated out-of-hospital cardiac arrest (OHCA) survivors is still a matter of debate. The aim of the study was to evaluate the impact of MTH on the platelet-inhibitory effect of ticagrelor in comatose survivors of OHCA treated with primary PCI.</p><p><strong>Methods: </strong>Eighteen comatose survivors of OHCA with acute coronary syndrome undergoing immediate PCI treated with MTH were compared with 14 patients with uncomplicated primary myocardial infarction after PCI, matched for gender and age, in a prospective, single-center, observational study. Platelet aggregation was evaluated using VerifyNow P₂Y₁₂ point-of-care testing at 3 time points: admission (T₀), during MTH (T₁), and 48-72 h after rewarming (T₂).</p><p><strong>Results: </strong>Ticagrelor effectively inhibits platelet aggregation in OHCA patients subjected to MTH and in all patients in the control group. The effectiveness of ticagrelor did not differ between the MTH group and the control group (p = 0.581). In 2 cases in the MTH population, the platelet response to ticagrelor was inadequate, and in one of them it remained insufficient during the re-warming phase. There was no stent thrombosis in these patients.</p><p><strong>Conclusions: </strong>The present study confirmed the effectiveness of ticagrelor to inhibit platelets in myocardial infarction patients after OHCA treated with primary PCI undergoing hypothermia. The use of cooling was not associated with an increased risk of stent thrombosis.</p>","PeriodicalId":9492,"journal":{"name":"Cardiology journal","volume":"30 4","pages":"636-645"},"PeriodicalIF":2.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/6d/96/cardj-30-4-636.PMC10508063.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10259292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coffee and cardiac arrhythmias: Up-date review of the literature and clinical studies.","authors":"Stanisław Surma,&nbsp;Monika Romańczyk,&nbsp;Krzysztof J Filipiak,&nbsp;Gregory Y H Lip","doi":"10.5603/CJ.a2022.0068","DOIUrl":"10.5603/CJ.a2022.0068","url":null,"abstract":"Coffee, next to water, is the most consumed drink in the world. Coffee contains over 1000 chemical compounds, the most popular of which are caffeine, chlorogenic acid, kahweol, cafestol and trigonelline. Numerous studies have shown the beneficial effects of coffee on the cardiovascular system, nervous system, digestive system and kidneys. Due to the high incidence of cardiac arrhythmias, especially atrial fibrillation, the influence of coffee consumption on arrhythmogenesis remains a controversial and clinically important issue. Many mechanisms by which coffee can increase and decrease the risk of arrhythmias have been described. Habitual consumption of moderate amounts of coffee seems to lead to less arrhythmias, which is reflected in the results of many clinical trials and meta-analyzes. This review summarizes the mechanisms of coffee action on the heart muscle and the results of the most recent important clinical trials assessing the impact of coffee consumption on the risk of various cardiac arrhythmias.","PeriodicalId":9492,"journal":{"name":"Cardiology journal","volume":"30 4","pages":"654-667"},"PeriodicalIF":2.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f2/be/cardj-30-4-654.PMC10508080.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10572656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}