Chonnam medical journalPub Date : 2023-09-01Epub Date: 2023-09-25DOI: 10.4068/cmj.2023.59.3.207
Yisik Kim, Sun Hwa Lee
{"title":"Eggshell Calcification in Progressive Constrictive Pericarditis.","authors":"Yisik Kim, Sun Hwa Lee","doi":"10.4068/cmj.2023.59.3.207","DOIUrl":"10.4068/cmj.2023.59.3.207","url":null,"abstract":"","PeriodicalId":94372,"journal":{"name":"Chonnam medical journal","volume":"59 3","pages":"207-208"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/11/6d/cmj-59-207.PMC10570861.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41242952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chonnam medical journalPub Date : 2023-09-01Epub Date: 2023-09-25DOI: 10.4068/cmj.2023.59.3.174
Young Kwon Koh, Han Gil Kang, Young Kuk Cho
{"title":"Effects of Dextrose Supplementation on Chloral Hydrate Sedation: A Double-Blinded, Randomized, Prospective Study.","authors":"Young Kwon Koh, Han Gil Kang, Young Kuk Cho","doi":"10.4068/cmj.2023.59.3.174","DOIUrl":"10.4068/cmj.2023.59.3.174","url":null,"abstract":"<p><p>Sedation plays a crucial role in successful pediatric imaging, and chloral hydrate is commonly used for this purpose. However, the challenges associated with chloral hydrate administration, such as its unpleasant taste and potential induction of vomiting, remain a concern. Sweet oral solutions have emerged as potential solutions for reducing distress and providing analgesia. This study compared the efficacy of dextrose combined with chloral hydrate with that of conventional sedation methods. This prospective, double-blind, randomized controlled clinical study enrolled 160 pediatric outpatients scheduled for echocardiography. Chloral hydrate syrup (100 mg/mL) was supplemented with a dextrose solution (dextrose group) or distilled water (control group) in a 1:10 volume ratio. The sedation achievement time, Skeie scale score, revised Face, Legs, Activity, Cry, and Consolability (FLACC) score, and side effects (nausea, vomiting, hypoxia, and respiratory depression) were assessed. No significant difference in average time to achieve sedation was observed between the dextrose and control groups (24.4±17.8 vs. 24.7±17.1 min, p=0.92). Both groups demonstrated similar levels of sedation according to the Skeie scale and mean revised FLACC score. Although the occurrence rates of nausea and vomiting had no significant differences, the dextrose group had no cases of vomiting in children aged >24 months compared to the control group, which had three cases (30%). In conclusion, the addition of dextrose to chloral hydrate did not significantly affect sedation time, anxiety, pain reduction, or occurrence of gastrointestinal complications during sedation.</p>","PeriodicalId":94372,"journal":{"name":"Chonnam medical journal","volume":"59 3","pages":"174-179"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/07/74/cmj-59-174.PMC10570855.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41242951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"<i>Helicobacter pylori</i> Eradication-Related Development of Multiple White and Flat Elevated Lesions in the Stomach.","authors":"Akira Hokama, Mayumi Shiroma, Mami Tomiyama, Yuko Tasato, Maki Setake","doi":"10.4068/cmj.2023.59.3.203","DOIUrl":"10.4068/cmj.2023.59.3.203","url":null,"abstract":"","PeriodicalId":94372,"journal":{"name":"Chonnam medical journal","volume":"59 3","pages":"203-204"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/36/ca/cmj-59-203.PMC10570868.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41242925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chonnam medical journalPub Date : 2023-09-01Epub Date: 2023-09-25DOI: 10.4068/cmj.2023.59.3.209
Hyun Kuk Kim, Sung Soo Kim, In Young Choi, Young Jae Ki, Dong Hyun Choi, Keun Ho Park
{"title":"A Successful Case of Radiofrequency Ablation of Multiple Accessory Pathways in Ebstein's Anomaly Using Intracardiac Echocardiography.","authors":"Hyun Kuk Kim, Sung Soo Kim, In Young Choi, Young Jae Ki, Dong Hyun Choi, Keun Ho Park","doi":"10.4068/cmj.2023.59.3.209","DOIUrl":"10.4068/cmj.2023.59.3.209","url":null,"abstract":"","PeriodicalId":94372,"journal":{"name":"Chonnam medical journal","volume":"59 3","pages":"209-210"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/40/da/cmj-59-209.PMC10570854.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41242926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chonnam medical journalPub Date : 2023-09-01Epub Date: 2023-09-25DOI: 10.4068/cmj.2023.59.3.200
Keizo Tanitame
{"title":"Pancreaticoduodenal Artery Aneurysm due to Median Arcuate Ligament Compression of the Celiac Artery.","authors":"Keizo Tanitame","doi":"10.4068/cmj.2023.59.3.200","DOIUrl":"10.4068/cmj.2023.59.3.200","url":null,"abstract":"","PeriodicalId":94372,"journal":{"name":"Chonnam medical journal","volume":"59 3","pages":"200-201"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/9f/68/cmj-59-200.PMC10570860.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41242957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chonnam medical journalPub Date : 2023-09-01Epub Date: 2023-09-25DOI: 10.4068/cmj.2023.59.3.196
Preet Mukesh Shah, Robert D Murray
{"title":"Rivaroxaban: A Rare Cause of Spontaneous Bilateral Adrenal Haematomas.","authors":"Preet Mukesh Shah, Robert D Murray","doi":"10.4068/cmj.2023.59.3.196","DOIUrl":"10.4068/cmj.2023.59.3.196","url":null,"abstract":"","PeriodicalId":94372,"journal":{"name":"Chonnam medical journal","volume":"59 3","pages":"196-197"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/3c/8b/cmj-59-196.PMC10570862.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41242959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chonnam medical journalPub Date : 2023-09-01Epub Date: 2023-09-25DOI: 10.4068/cmj.2023.59.3.143
Mohammad Amin Amini, Ashkan Karbasi, Mohammad Vahabirad, Masoud Khanaghaei, Aida Alizamir
{"title":"Mechanistic Insight into Age-Related Macular Degeneration (AMD): Anatomy, Epidemiology, Genetics, Pathogenesis, Prevention, Implications, and Treatment Strategies to Pace AMD Management.","authors":"Mohammad Amin Amini, Ashkan Karbasi, Mohammad Vahabirad, Masoud Khanaghaei, Aida Alizamir","doi":"10.4068/cmj.2023.59.3.143","DOIUrl":"10.4068/cmj.2023.59.3.143","url":null,"abstract":"<p><p>One of the most complicated eye disorders is age-related macular degeneration (AMD) which is the leading cause of irremediable blindness all over the world in the elderly. AMD is classified as early stage to late stage (advanced AMD), in which this stage is divided into the exudative or neovascular form (wet AMD) and the nonexudative or atrophic form (dry AMD). Clinically, AMD primarily influences the central area of retina known as the macula. Importantly, the wet form is generally associated with more severe vision loss. AMD has a systemic component, where many factors, like aging, genetic, environment, autoimmune and non-autoimmune disorders are associated with this disease. Additionally, healthy lifestyles, regular exercise, maintaining a normal lipid profile and weight are crucial to decreasing the risk of AMD. Furthermore, therapeutic strategies for limiting AMD should encompass a variety of factors to avoid and improve drug interventions, and also need to take into account personalized genetic information. In conclusion, with the development of technology and research progress, visual impairment and legal blindness from AMD have been substantially reduced in incidence. This review article is focused on identifying and developing the knowledge about the association between genetics, and etiology with AMD. We hope that this review will encourage researchers and lecturers, open new discussions, and contribute to a better understanding of AMD that improves patients' visual acuity, and upgrades the quality of life of AMD patients.</p>","PeriodicalId":94372,"journal":{"name":"Chonnam medical journal","volume":"59 3","pages":"143-159"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/39/9a/cmj-59-143.PMC10570864.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41242955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chonnam medical journalPub Date : 2023-09-01Epub Date: 2023-09-25DOI: 10.4068/cmj.2023.59.3.205
Keizo Tanitame, Hayato Araki
{"title":"Diffusion Weighted Imaging in a Patient with Transient Global Amnesia.","authors":"Keizo Tanitame, Hayato Araki","doi":"10.4068/cmj.2023.59.3.205","DOIUrl":"10.4068/cmj.2023.59.3.205","url":null,"abstract":"","PeriodicalId":94372,"journal":{"name":"Chonnam medical journal","volume":"59 3","pages":"205-206"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c9/44/cmj-59-205.PMC10570866.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41242929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chonnam medical journalPub Date : 2023-09-01Epub Date: 2023-09-25DOI: 10.4068/cmj.2023.59.3.160
Thuy Thi Nguyen, Hien Duong Thanh, Manh-Hung Do, Chaeyong Jung
{"title":"Complement Regulatory Protein CD46 Manifests a Unique Role in Promoting the Migration of Bladder Cancer Cells.","authors":"Thuy Thi Nguyen, Hien Duong Thanh, Manh-Hung Do, Chaeyong Jung","doi":"10.4068/cmj.2023.59.3.160","DOIUrl":"10.4068/cmj.2023.59.3.160","url":null,"abstract":"<p><p>CD46 is a membrane-bound complement regulatory protein (mCRP) possessing a regulatory role with the complement system. CD46 protects the host cells from damage by complement. Expression of CD46 is also highly maintained in many cancers, including bladder cancers, and thus functions as a receptor for many cancer therapeutic viruses. In this study we report a unique role of CD46 as a progression factor of cancer cells in bladder cancers. Resulting data from a DNA microarray using CD46-altered HT1376 bladder cancers demonstrated a pool of target genes, including complement C3 α chain (C3α), matrix Gla protein (MGP), AFAP-AS1, follicular dendritic cell secreted protein (FDCSP), MAM domain containing 2 (MAMDC2), gamma-aminobutyric acid A receptor pi (GABRP), transforming growth factor, beta-induced (TGFBI), a family of cytochrome P450 (CYP24A1), sialic acid binding Ig-like lectin 6 (SIGLEC6), metallothionein 1E (MT1E), and several members of cytokeratins. Subsequent studies using quantitative RT-PCR and Western blot analyses confirmed CD46-mediated regulation of C3α, MGP, and keratin 13 (KRT13). MGP and KRT13 are known to be involved in cell migration and cancer cell metastasis. A cell migration assay demonstrated that CD46 enhanced migratory potential of bladder cancer cells. Taken all together, this report demonstrated that CD46 is generally overexpressed in bladder cancers and plays a unique role in the promotion of cancer cell migration. Further detailed studies are needed to be performed to clarify the action mechanism of CD46 and its application to cancer therapeutics.</p>","PeriodicalId":94372,"journal":{"name":"Chonnam medical journal","volume":"59 3","pages":"160-166"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/cc/7e/cmj-59-160.PMC10570858.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41242928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}