Lymphology最新文献

{"title":"Report on the second Indian Congress (Lymphocon) held in Chennai, India 9-10 November 2024.","authors":"S Michelini","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Report on the Second Indian National Congress (Lymhocon) held Novemebr 9 and 10, 2024.</p>","PeriodicalId":94343,"journal":{"name":"Lymphology","volume":"57 4","pages":"219-221"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144056583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter: BioBridge^TM Collagen Matrix for Lymphedema Therapy.","authors":"M Paukshto, G King","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Letter in response to article: Witt, M, A Ring: Handley's Thread Lymphangioplasty Vs. BioBridge^TM Collagen Matrix for Lymphedema Therapy-Old Wine in New Bottles? Lymphology 56 (2023) 110-120.</p>","PeriodicalId":94343,"journal":{"name":"Lymphology","volume":"57 2","pages":"104-106"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142635702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Relationship Between Disease Variables, Pain Coping, and Functional Status of Patients with Lower Extremity Lymphedema.","authors":"L Huseyinli, A B Aydin, D Altug, M A Cakmak, O B Tuncer, Y Tuglu, O Kenis-Coskun, C Sanal-Toprak","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The purpose of this study is to investigate the relationship between reported symptoms, functional outcomes, and pain coping mechanisms in participants with lower limb lymph-edema. This research has been designed as cross-sectional. Participants' age, sex, height, weight, pain, tightness, and stiffness levels reported by the participants were documented with a 10 cm visual analogue scale. The Pain Coping Inventory scale has been used to evaluate coping strategies. Functional status was measured with timed-up-and-go test (TUGT), six-minute walk test (6MWT), and quadriceps muscle strength measurement with a hand-held dynamometer. The functional outcomes were also measured in a healthy control group. The difference in muscle strength in both lower extremities was evaluated using the t-test, and the correlations were assessed using the Spearman correlation test. Twenty-eight participants with lymphedema (PWL) and 23 controls were included in the study. Twenty-three of the PWL were female (82%). The mean age of the PWL was 54.43 ± 14.12, and the mean body mass index was 33.84 ± 6.17. There were no significant differences between the PWL and healthy controls regarding age and sex. The mean muscle strength of the affected lower extremity was 4.21 ± 1.10 kgs and was significantly lower compared to the contralateral lower extremity (6.10 ± 2.98 kgs) and control group (10.92 ± 1.25 kgs) (p<0.05 and p=0.007 respectively). In functional outcomes, TUGT was significantly worse in PWL when compared to the control group (11.17 ± 3.28 seconds vs 9.04 ± 1.33 seconds, p=0.004). A significant correlation was observed between the TUGT result and the level of tightness felt by the PWL (r= 0.43, p=0.02). There were significant correlations between pain coping strategies and patient reported symptoms. No correlations were found between coping strategies and functional measurements. Lymphedema disrupts the functional status of the participants, and these functional disruptions may be related to symptoms reported by the participants. The correlation between pain coping strategies and patient reported tightness may indicate that tightness may be more influential on coping with pain, but further research is needed to determine a cause-and-effect relationship.</p>","PeriodicalId":94343,"journal":{"name":"Lymphology","volume":"57 2","pages":"97-103"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142635705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Returning the Central Lymphatic System to the Center of Lymphology.","authors":"M H Witte","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>After the introduction of conventional oil contrast lymphography and the founding of the discipline of lymphology, great impetus was given to investigating central lymphatic system and its disorders along with lymphatic involvement and specifically lymphostasis in common diseases of major organs such as the liver (cirrhosis) and heart (heart failure). Gradually interest shifted to more peripheral disorders such as limb lymphedema and its treatment by physical and surgical measures. At the same time, basic lymphology turned to the study of isolate-ed ex vivo and in vitro, including lymphatic endothelial models and more recently, molecular lymphology focusing on lymphatic growth and modulating factors, genes and proteins under-lying primary lymphedema, and more potential biomarkers of lymphatic disease have gained prominence. However, it has been advances in lymphatic imaging, namely lymphoscintigraphy with SPECT-CT high resolution 3-D pictures and magnetic resonance imaging (contrast and non-contrast) of the peripheral and particularly central lymphatic system by more invasive means combined with endovascular interventional techniques to treat complex and life-threatening lymphatic disorders that has returned the central lymphatic system to the center of lymphology, where the journey began.</p>","PeriodicalId":94343,"journal":{"name":"Lymphology","volume":"57 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142485058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Added Effect of Artificial Intelligence in CT Assessment of Abdominal Lymphadenopathy.","authors":"R A Meshref, I A Saleem, A A Salama, S H Darwish, S M El-Kholy, E I Mohame","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Lymphadenopathy is associated with lymph node abnormal size or consistency due to many causes. We employed the deep convolutional neural network ResNet-34 to detect and classify CT images from patients with abdominal lymphadenopathy and healthy controls. We created a single database containing 1400 source CT images for patients with abdominal lymphadenopathy (n = 700) and healthy controls (n = 700). To train, test, and cross-validate the ResNet-34 classifier to detect specific lesions, we first resized and normalized all images. Then, we randomly divided the 1400 images into 88 groups of 16, and the classifier was trained to identify and label lesions using automatic volume delineation 3D reconstruction of target areas. The ResNet-34 had a diagnostic accuracy with receiver operating characteristic (ROC) curves of the true-positive rate versus the false-positive rate with the area under the curve (AUC) of 0.9957 and 1.00 for abdominal lymphadenopathy and healthy control CT images, respectively. This accuracy implied identical high sensitivity and specificity values of 99.57 % and 100% for the two groups. The added effect of ResNet-34 is a success rate of 99.57% and 100% for classifying random CT images of the two groups, with an overall accuracy of 99.79% in the testing subset for detecting and classifying lymph node lesions. Based on this high classification precision, we believe the output activation map of the final layer of the ResNet-34 is a powerful tool for the accurate diagnosis of lymph node lesions of abdominal lymphadenopathy from CT images.</p>","PeriodicalId":94343,"journal":{"name":"Lymphology","volume":"57 3","pages":"132-141"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143054717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lymphology Milestone Coming in 2025-26: 60-Year Lymphology Trifecta to Commemorate Founding of the Discipline of Lymphology and the International Society of Lymphology.","authors":"M H Witte, M Bernas","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>2025-26 marks 60 years since the founding of the discipline of Lymphology. Landmarks in the history of the discipline are chronicled highlighting seminal contributions of ISL members. As we look back to celebrate and commemorate our history and the explosive growth of the field, a trifecta of international conferences, all significantly contributed to by the ISL, are planned as we simultaneously look forward to the bright future of the ISL and the discipline of Lymphology.</p>","PeriodicalId":94343,"journal":{"name":"Lymphology","volume":"57 4","pages":"180-185"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144061813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In Memoriam: Iwona Swedborg; 1936-2024.","authors":"K Johansson, H Brorson","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In Memoriam for Iwona Swedborg a lymphology pioneer and participant in the founding of the Swedish Society of Lymphology; 1936-2024.</p>","PeriodicalId":94343,"journal":{"name":"Lymphology","volume":"57 3","pages":"171-172"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143054568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validation of a New Measurement Device (Perikit®) For Perimetry and Volumetry of The Lower Limb: Metrological and Intra-Observer Comparative Study.","authors":"M Louys, M Mathieu, S Harnie, N Adriaenssens","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Accurate quantitative assessments are crucial to understanding development of diseases and their effective treatments. Various validated perimetry and volumetry measurement methods for patients with lymphedema exist and each has its own advantages and limitations and choosing the right instrument is essential. PeriKit® (PK) is a new measurement device that requires validation. This single-blind, cross-sectional study compared three assessment methods for perimetry and volumetry of the lower limb: conventional tape measure (CTM); optoelectronic infrared volumeter (Perometer®) (OS) as the gold standard); and PK. Correlation coefficients between measurements were \"strong\" to \"very strong\". The ICC of the lower limb was the highest for PK (0.995), followed by the CTM (0.986) and the OS (0.974). PK had the lowest dispersion of results for all segments. Despite its poor reliability, CTM is widely used because of its low cost and portability. The OS is simple, ergonomic, and doesn't require calibration, but suffers from imperfections such as the absence of distal extremities (i.e. feet, hands, fingers, etc.) as well as cost. PK has succeeded in reducing many of the problems associated with measurement thanks to its standardized methodology which offers high repeatability. PK can replace OS and CTM, but OS or CTM can't replace PeriKit® because they are more dispersed and less accurate.</p>","PeriodicalId":94343,"journal":{"name":"Lymphology","volume":"57 3","pages":"116-131"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143054721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physiology and Functional Pathology of the Lymphatic System with Implications for the Fontan Patient.","authors":"V Hjortdal","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Contractile function of the collecting lymphatic vessels depend on smooth muscle cells, one-way valves, surrounding tissues, and regulation by the autonomic nervous system. The potentially deleterious effects of the Fontan procedure and elevated central venous pressure on lymphatic function leading to life-threatening complications are described. Presented at the 2023 ISL International Congress of Lymphology, Genoa, Italy in a special symposium on central and regional lymphatic system in health and disease.</p>","PeriodicalId":94343,"journal":{"name":"Lymphology","volume":"57 1","pages":"16-18"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142485056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prospective 2 Year Review of Lymphedema Rates in Breast Cancer Patients Following Mastectomy, Axillary Clearance, and Immediate Free Flap Breast Reconstruction.","authors":"M Anderson, D Hamilton, A Munnoch","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The reported incidence of lymphedema varies greatly among women treated for breast cancer, making counselling for surgery challenging. This study assessed the incidence of lymphedema in patients undergoing mastectomy and free flap reconstruction using robust, quantifiable, and replicable diagnostic criteria. Data on limb circumference, limb volume, and reported symptoms was collected prospectively pre-operatively, post operatively, and at 2 years. All patients undergoing skin sparing mastectomy with axillary node clearance and immediate free tissue breast reconstruction between 2009 and 2018 were included. We followed 113 patients to 2-year follow-up. The prevalence of patients meeting two identifying criteria was highest in the immediate post-operative period at 11%, falling to 4% at 2 years. The proportion of patients meeting three criteria remained static from the post-operative period to two years at 7%, though the incidence declined over that period. All the patients with three identifying criteria post-operatively and at two years had received either chemotherapy or chemotherapy and radiotherapy. Clear diagnostic criteria are important for the accurate assessment and study of post operative lymphedema. It is possible that free tissue transfer could reduce the incidence of or delays the onset of lymphedema in patients undergoing mastectomy and axillary clearance.</p>","PeriodicalId":94343,"journal":{"name":"Lymphology","volume":"57 4","pages":"191-197"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144016169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}