JEADV clinical practice最新文献

{"title":"Incidental pigmented basal cell carcinoma discovered on positron emission tomography (PET)","authors":"Yasaman Jazaeri,&nbsp;Véronique Del Marmol,&nbsp;Mariano Suppa,&nbsp;Nicolas Dumarey","doi":"10.1002/jvc2.434","DOIUrl":"10.1002/jvc2.434","url":null,"abstract":"<p>Basal cell carcinoma (BCC), which frequently occurs in sun-exposed areas of the head and neck region, is the most common cutaneous malignancy but the least studied with radiologic imaging techniques. This article outlines the case of a 65-year-old male with a pigmented BCC of the right shoulder discovered on positron emission tomography-computed tomography (PET/CT). The lesion was initially suspected as a melanoma. However, the histopathological features showed a tumor of basaloid cells. PET/CT is an excellent technique for the detection of hypermetabolic tumors, such as melanoma, squamous cell and Merkel cell carcinomas, in lymph nodes and distant organs. The usefulness of PET is limited for slowly growing tumors, such as BCC. However, PET/CT can be useful for the detection of distant metastasis in locally advanced BCC as well as in the follow-up of locally advanced BCC on Hedgehog inhibitors.</p>","PeriodicalId":94325,"journal":{"name":"JEADV clinical practice","volume":"3 4","pages":"1258-1261"},"PeriodicalIF":0.0,"publicationDate":"2024-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jvc2.434","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140982192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ocular rosacea: The often-overlooked component of rosacea","authors":"Ryan S. Q. Geng,&nbsp;Jacqueline Slomovic,&nbsp;Adrienn N. Bourkas,&nbsp;Allan Slomovic,&nbsp;Ronald G. Sibbald","doi":"10.1002/jvc2.428","DOIUrl":"10.1002/jvc2.428","url":null,"abstract":"<p>Ocular rosacea is a chronic inflammatory condition that affects the eyes and periocular skin as part of the broader cutaneous rosacea skin disease. Cutaneous rosacea is common, affecting approximately 5.5% of the global population, where up to 72% of patients will develop ocular involvement either before or after the cutaneous disease. Clinical features of ocular rosacea include Meibomian gland disease, blepharitis and conjunctivitis. Ocular rosacea reduces quality of life through various potential mechanisms including anxiety, social withdrawal and physical discomfort. If left untreated, ocular rosacea can reduce visual acuity and in severe cases, vision loss. Several topical and systemic treatment options are available, with efficacies based on their anti-inflammatory properties. This review focuses on the clinical features of ocular rosacea, differential diagnoses and treatment options with the aim of aiding clinicians involved in the care of rosacea patients to better identify onset of the ocular manifestations of rosacea and prevent its severe complications.</p>","PeriodicalId":94325,"journal":{"name":"JEADV clinical practice","volume":"3 5","pages":"1349-1363"},"PeriodicalIF":0.0,"publicationDate":"2024-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jvc2.428","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140982885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rapid and sustained improvement of psoriasis with Bimekizumab: A real-world case series","authors":"Sergio Santos-Alarcón,&nbsp;Francisco Javier Mataix-Diaz,&nbsp;Constantin Luca Schneller-Pavelescu Apetrei,&nbsp;Isabel Belinchón-Romero","doi":"10.1002/jvc2.457","DOIUrl":"10.1002/jvc2.457","url":null,"abstract":"<p>This retrospective case series examines the efficacy and safety of Bimekizumab in 22 patients with moderate to severe plaque psoriasis in a real-world clinical setting. The demographic and clinical characteristics of the participants, including a mean age of 43.7 years and a gender distribution of 60% male and 40% female, are summarised. Notably, 70% of the patients had previously received systemic therapy, and 50% had concurrent psoriatic arthritis. The evaluation over a 12-week treatment period revealed a significant reduction in psoriasis area and severity index scores from a baseline mean of 11.5−1.0 at Week 4 and further down to 0.3 by Week 12. Similar improvements were observed in body surface area, physician's global assessment and dermatology life quality index scores. Bimekizumab was well-tolerated with no reported adverse events, leading to no treatment discontinuations. These findings highlight the potential of Bimekizumab to provide rapid and sustained improvements in patients with moderate to severe plaque psoriasis, underlining its value in clinical practice.</p>","PeriodicalId":94325,"journal":{"name":"JEADV clinical practice","volume":"3 4","pages":"1270-1273"},"PeriodicalIF":0.0,"publicationDate":"2024-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jvc2.457","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140986360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Henoch–Schönlein purpura following COVID-19 vaccine","authors":"Nesrine Ben Salah,&nbsp;Maha Lahouel,&nbsp;Lella Douh,&nbsp;Khaoula Trimeche,&nbsp;Amina Aounallah,&nbsp;Amira Atig,&nbsp;Colandane Belajouza,&nbsp;Mohamed Denguesli","doi":"10.1002/jvc2.454","DOIUrl":"10.1002/jvc2.454","url":null,"abstract":"<p>Henoch–Schönlein purpura (HSP) is an immunoglobulin A (IgA)-mediated small-vessel vasculitis mostly observed in children and rarely in adults. It can affect many organs, mainly the skin, kidneys, joints, and gastrointestinal tract. We report a case of HSP occurring after COVID-19 vaccine (Pfizer-BioNTech).</p>","PeriodicalId":94325,"journal":{"name":"JEADV clinical practice","volume":"3 4","pages":"1212-1214"},"PeriodicalIF":0.0,"publicationDate":"2024-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jvc2.454","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140986809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cutaneous manifestations of anti-synthetase syndrome: Case series and literature review","authors":"Airiss R. Chan,&nbsp;Mohamed Osman,&nbsp;Elaine Yacyshyn,&nbsp;Robert Gniadecki","doi":"10.1002/jvc2.443","DOIUrl":"10.1002/jvc2.443","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Anti-synthetase syndrome (ASyS) is a rare inflammatory myopathy associated with anti-aminoacyl transfer RNA synthetase antibodies, and is characterized by a triad of interstitial lung disease, arthritis, and myopathy. ASyS has been considered to represent a subtype of dermatomyositis (DM), however it is not clear whether cutaneous findings overlap in both diseases.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>We aimed to characterize mucocutaneous features which should raise suspicion of ASyS and prompt early diagnostic testing.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We reviewed 28 cases of ASyS in our institution, and retrieved data from 43 articles reporting clinical features of ASyS in the literature.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Dermatologic manifestations of ASyS can be categorized as: specific cutaneous signs strongly associated with ASyS (‘Mechanic's hands’, ‘Hiker's feet’); mucocutaneous signs overlapping with other collagenoses; nailfold changes (resembling those of DM and systemic sclerosis); and mucocutaneous signs of undetermined significance. Only 20% had pathognomonic DM signs.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Dermatologic manifestations of ASyS are heterogeneous and do not always reproduce the pattern seen in DM. Presence of palmar hyperkeratosis (‘Mechanic's hands’), cuticular overgrowth, skin ulcerations and nailfold capillary changes should prompt further diagnostic workup of ASyS. Limitations of our study include inconsistent reporting of dermatologic findings within our series between virtual and in-person visits. Not all patients were seen in dermatology consultation.</p>\u0000 </section>\u0000 </div>","PeriodicalId":94325,"journal":{"name":"JEADV clinical practice","volume":"3 4","pages":"1148-1156"},"PeriodicalIF":0.0,"publicationDate":"2024-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jvc2.443","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140994550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk of adverse events in patients with bullous pemphigoid treated with oral corticosteroids in the United States","authors":"Jonathan I. Silverberg,&nbsp;Feifei Yang,&nbsp;Evo Alemao,&nbsp;Jing Zhao,&nbsp;Concetta Crivera,&nbsp;Hetal V. Patel,&nbsp;Iris Lin,&nbsp;Aaron R. Mangold","doi":"10.1002/jvc2.444","DOIUrl":"10.1002/jvc2.444","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>The potential association of long-term oral corticosteroid (OCS) use with adverse events (AEs) in patients with bullous pemphigoid (BP) is not well characterized in a real-world setting.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To evaluate the effect of OCS use and treatment duration on the incident AEs in patients with BP.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This retrospective cohort study used medical and pharmacy claims and patient enrollment data from IQVIA PharMetrics® Plus from 2006−2021. Eligible patients had a diagnosis of BP between 1 January 2006 and 30 June 2020 (≥2 claims for BP ≥ 30 days apart). Patients in the OCS cohort also had a claim for OCS use, ≥7.5 mg daily dose of prednisone or equivalent, and no claims for a nonoral systemic corticosteroid (CS) at any time during the study period. A control cohort of patients with BP not using OCS was also selected. Relative risk ratios were estimated between the incidence of AEs in OCS users with different exposure durations (short-term, &lt;30 days; medium-term, 30−90 days; long-term, &gt;90 days) and nonusers by Poisson regression, after adjusting for age, sex, prior drug use, and baseline Charlson Comorbidity Index score within the follow-up period.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>At the 1-year follow-up, long-term OCS users had a higher incidence of infections, cataract, osteoporosis, heart failure, depression or anxiety, and diabetes compared with OCS nonusers (<i>p</i> &lt; 0.05). Furthermore, compared with nonusers, long-term users had increased 1-year risks (risk ratio; 95% confidence interval) for heart failure (2.27; 1.50−3.44), diabetes (2.05; 1.30−3.24), osteoporosis (1.72; 1.23−2.41), and infection (1.50; 1.13−1.99). Long-term OCS users also had increased 1-year risks for heart failure (2.00; 1.21−3.28) and osteoporosis (1.70; 1.16−2.50) compared with short-term OCS users.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Long-term OCS use (≥7.5 mg) in patients with BP was associated with an increased risk of AEs. Study findings demonstrate a need for steroid-sparing options with an improved safety profile.</p>\u0000 </section>\u0000 </div>","PeriodicalId":94325,"journal":{"name":"JEADV clinical practice","volume":"3 4","pages":"1206-1211"},"PeriodicalIF":0.0,"publicationDate":"2024-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jvc2.444","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140995444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The doctors' perception of skin diseases in general practice in Denmark, with emphasis on atopic dermatitis: A descriptive study","authors":"Anne Sofie Froelunde,&nbsp;Mette Deleuran,&nbsp;Janus L. Thomsen,&nbsp;Christian Vestergaard","doi":"10.1002/jvc2.426","DOIUrl":"10.1002/jvc2.426","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Skin symptoms are a common reason for consulting a medical doctor, for example a general practitioner (GP) in countries where GPs function as gatekeepers. Despite this, GPs have very sparse dermatological training in their Residency programme.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To investigate management and challenges of skin diseases, in particular atopic dermatitis (AD), in general practice from the GPs' point of view.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A survey was sent out to all 298 GPs in the North Region of Denmark on 5 April 2022 and data collection continued until 8 June 2022. The survey contained three sections; demographic information about the GP, patients with dermatological problems in general practice, and lastly load, management, and perception of AD in general practice.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 94 GPs (31.5%) responded to the survey. Sixty-four percent of the GPs reported that 5%–10% of their consultations concerned dermatology, and 25% reported that in more than 10% of their consultations, patients have a secondary skin problem. Top three most frequent skin diagnoses were rated to be seborrhoeic keratoses, children with AD, and acne.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Consultations for skin diseases are very common in general practice, and very often, patients bring up their skin issue secondary to another problem. Forty-three percent of GPs in our study had taken postgraduate training in dermatology, which underlines the need for more dermatological education in the GPs' residency programme. Patients with AD are treated according to guidelines, and GPs find consultations with patients with AD complex. Lastly, there is a high rate of reconsultations for patients with AD.</p>\u0000 </section>\u0000 </div>","PeriodicalId":94325,"journal":{"name":"JEADV clinical practice","volume":"3 4","pages":"1095-1101"},"PeriodicalIF":0.0,"publicationDate":"2024-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jvc2.426","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140996509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Local procedures for axillary hyperhidrosis and osmidrosis: A systematic review of prospective and controlled clinical trials","authors":"Gabriela L. Grove,&nbsp;Mattias A. S. Henning,&nbsp;Katrine Togsverd-Bo,&nbsp;Catherine M. DiGiorgio,&nbsp;Mathew M. Avram,&nbsp;Merete Haedersdal","doi":"10.1002/jvc2.415","DOIUrl":"10.1002/jvc2.415","url":null,"abstract":"<p>Axillary hyperhidrosis and osmidrosis are challenging to treat, and neither topical nor systemic drugs have provided optimal treatment outcomes. In the past decades, treatment with botulinum toxin (BTX) has gained status as the gold standard, but it has its limitations both in regard to duration as well as indication for osmidrosis, specifically. A variety of local interventions have been explored in both the surgical field and within energy-based devices (EBDs) for alternative in-office treatments, but a collective overview is lacking. This study sought to investigate and assess the evidence on and effect of current local procedures for axillary hyperhidrosis and osmidrosis. A systematic search for prospective and controlled clinical trials in the databases PubMed, Embase and Cochrane Library until 31 December 2023 was executed. Relevant literature was identified independently by two authors according to predefined inclusion and exclusion criteria. Fifty-nine studies met the criteria for final inclusion, of which 46 studies were randomized controlled trials and 13 were nonrandomized trials. The included studies were classified by procedure type. Individually, a total of 28 studies investigated BTXs, 11 studies explored EBDs, while six studies reported on surgical interventions. Additionally, 14 studies evaluated alternative procedures or investigated combinations and side-by-side comparisons of the different procedure types. The dominant evidence on efficacy and safety was of BTX A. EBDs are increasingly being investigated with microwave thermolysis appearing to be the singular most established and scientifically well-founded method. In the surgical field, less-invasive methods are gaining ground. To meet the increasing demand for individualized treatment, additional high-quality comparative studies are required for the establishment of a future variety of standard treatments.</p>","PeriodicalId":94325,"journal":{"name":"JEADV clinical practice","volume":"3 4","pages":"972-1004"},"PeriodicalIF":0.0,"publicationDate":"2024-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jvc2.415","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140997911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tucumã tree thorn granuloma","authors":"Carolina Viza Amorim,&nbsp;Icléia Siqueira Barreto,&nbsp;Jéssica Barbosa Camargos Dias,&nbsp;Mirella Pinotti,&nbsp;Vitória Jugni,&nbsp;Fernanda Oliveira Camargo Herreros","doi":"10.1002/jvc2.440","DOIUrl":"10.1002/jvc2.440","url":null,"abstract":"&lt;p&gt;Barco da Saúde (Health Boat) is a project of the University of São Leopoldo Mandic that aims to bring voluntary medical and dental care to communities bordering the Tapajós River, in the state of Pará, Brazil. In its 4th edition in 2023, 134 dermatological treatments were carried out, most of them inside the hospital boat. Many patients were farmers and fishermen, exposed to the occupational risks inherent to these activities in the Brazilian Amazon region. Of the work carried out by riverside dwellers, we highlight the harvest of tucumã, the fruit of the tucumã tree, which is a typical palm tree from the Amazon region that belongs to the genus &lt;i&gt;Astrocaryum&lt;/i&gt;. Its striking feature is the presence of black, flexible thorns in almost all parts of the plant,&lt;span&gt;&lt;sup&gt;1&lt;/sup&gt;&lt;/span&gt; which can reach 15 cm in length. Its fruit is of great socioeconomic importance for the Amazon population. Several families survive thanks to the extraction of this fruit. Tucumã, in addition to being used in oil extraction, is highly appreciated in local cuisine and can be consumed fresh. It is rich in beta-carotene and flavonoids and Brazilian cosmetics companies are adding tucumã to their products for its alleged antioxidant capacity.&lt;span&gt;&lt;sup&gt;2&lt;/sup&gt;&lt;/span&gt;&lt;/p&gt;&lt;p&gt;We describe the case of a 34-year-old male patient who is a black farmer from the Açaiatuba Community in Pará, Brazil. The patient reported that 3 years earlier he had fallen on a tucumã tree and that several thorns had injured his arms. He extracted the thorns from the skin manually but after a few months he noticed a nodule on his left forearm. Physical examination revealed a nodule measuring approximately 3 × 2 cm, normochromic, moveable, not deeply attached and slightly painful on palpation on the extensor surface of the left forearm. Suspecting a foreign body granuloma (FBG), a surgical approach was chosen. Macroscopic analysis of the surgical specimen revealed material with a pointed shape and a blackish colour. On microscopic analysis, histological sections stained with hematoxylin-eosin revealed chronic inflammation with eosinophils, associated with a focus of necrosis and the presence of plant cells (Figure 1), confirming the diagnosis of FBG added to allergic reaction.&lt;/p&gt;&lt;p&gt;FBG, also called non-immunological granuloma, is a tissue reaction that develops due to the penetration of substances through the skin accidentally or on purpose.&lt;span&gt;&lt;sup&gt;3&lt;/sup&gt;&lt;/span&gt; FBG is caused by substances that are unable to elicit a specialised immune response (mediated by T lymphocytes). On histopathological examination, FBG is characterised by the presence of identifiable foreign material, surrounded by histiocytes, multinucleated giant cells and a variable number of other inflammatory cells.&lt;span&gt;&lt;sup&gt;4&lt;/sup&gt;&lt;/span&gt; Some authors propose that plant induced injuries, particularly cactus spines, can additionally induce an allergic reaction to vegetal antigens, because not every patient develops granulomatous ","PeriodicalId":94325,"journal":{"name":"JEADV clinical practice","volume":"3 4","pages":"1301-1302"},"PeriodicalIF":0.0,"publicationDate":"2024-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jvc2.440","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141004757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Immunotherapy associated Sweet syndrome in a patient with metastatic melanoma: A case report","authors":"Rory Barry,&nbsp;Gregg Murray,&nbsp;Sally McGrath,&nbsp;Clive Kilgallen,&nbsp;Karen Eustace","doi":"10.1002/jvc2.445","DOIUrl":"10.1002/jvc2.445","url":null,"abstract":"<p>Immunotherapy agents are now widely used in the treatment of metastatic melanoma. Immune-related adverse events (irAEs) may occur, including cutaneous pathologies in 50% of patients. We report a case of Sweet syndrome (SS) in a patient who was prescribed ipilimumab and nivolumab for metastatic melanoma.</p>","PeriodicalId":94325,"journal":{"name":"JEADV clinical practice","volume":"3 4","pages":"1267-1269"},"PeriodicalIF":0.0,"publicationDate":"2024-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jvc2.445","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141010905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}