JEADV clinical practice最新文献

筛选
英文 中文
Itch improvement has a major and comparable effect on the Dermatology Life Quality Index in psoriasis and atopic dermatitis patients 瘙痒的改善对银屑病和特应性皮炎患者的皮肤病生活质量指数具有重要且可比的影响
JEADV clinical practice Pub Date : 2024-08-08 DOI: 10.1002/jvc2.509
Wolf-Henning Boehncke, A. Reich, Sonja Ständer, Julio Hernandez, C. Mert, S. Grond, M. J. Rueda, C. Schuster, Gil Yosipovitch
{"title":"Itch improvement has a major and comparable effect on the Dermatology Life Quality Index in psoriasis and atopic dermatitis patients","authors":"Wolf-Henning Boehncke, A. Reich, Sonja Ständer, Julio Hernandez, C. Mert, S. Grond, M. J. Rueda, C. Schuster, Gil Yosipovitch","doi":"10.1002/jvc2.509","DOIUrl":"https://doi.org/10.1002/jvc2.509","url":null,"abstract":"Itch is known to have a particularly high impact on psoriasis (PsO) and atopic dermatitis (AD) patients' quality of life. Although AD therapies have exhibited a high efficacy when it comes to itch control, itch control with PsO therapies is not as well documented.The aim of this post‐hoc analysis is to better understand the impact of itch on the patients' quality of life in PsO as well as AD by providing a pairwise correlation between itch improvement and patients' quality of life and determine the predictive factors in patients achieving Dermatology Life Quality Index score of 0 or 1 [DLQI (0/1)].Three phase III clinical studies, one in PsO and two in AD, were assessed. Pairwise correlations between objective improvement of visible signs of disease, quality of life, and itch intensity were investigated at 16 weeks of treatment. Predictive analyses methods were applied on the data to assess the impact of clinical and itch improvement on the DLQI improvement.This study shows that change in itch from baseline in AD and PsO patients correlate to change in DLQI from baseline. Change in itch from baseline was found to be the most important factor in predicting DLQI (0/1).These results highlight the necessity to study itch in both PsO and AD clinical trials, and it is recommended that itch may be considered a coprimary or at minimum a secondary efficacy end‐point in all such clinical studies.","PeriodicalId":94325,"journal":{"name":"JEADV clinical practice","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141927095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sjögren syndrome from a dermatological perspective: A retrospective study of 185 SSA‐Ro positive patients 从皮肤科角度看斯约格伦综合征:185 例 SSA-Ro 阳性患者的回顾性研究
JEADV clinical practice Pub Date : 2024-07-19 DOI: 10.1002/jvc2.498
Fiona André, Martha Bujak, Nina Frischhut, Andreas Kronbichler, N. Sepp, G. Ratzinger, Barbara Böckle
{"title":"Sjögren syndrome from a dermatological perspective: A retrospective study of 185 SSA‐Ro positive patients","authors":"Fiona André, Martha Bujak, Nina Frischhut, Andreas Kronbichler, N. Sepp, G. Ratzinger, Barbara Böckle","doi":"10.1002/jvc2.498","DOIUrl":"https://doi.org/10.1002/jvc2.498","url":null,"abstract":"Sjögren syndrome (SS) is a systemic autoimmune disease characterised by oral and ocular mucosal dryness.Our study focused on skin manifestations of SS. The differences between primary SS (pSS) and secondary SS (sSS) were investigated. Furthermore, we elucidated factors predicting internal organ involvement.This was a single centre retrospective cohort study. We analysed clinical and laboratory data from 185 Ro‐SSA positive SS patients between January 2000 and December 2016.Skin manifestations were present in 74.9% (n = 137) of SS patients. Dermatitis and Lupus erythematosus (LE)‐specific skin manifestations were present in 34.1% (n = 63) and 21.6% (n = 40) of SS patients respectively. 65.9% (n = 122) of SS patients had internal organ involvement, with 53% (n = 98) presenting neuropsychiatric manifestations. Several risk factors for internal organ involvement were identified: presence of myalgia/arthralgia (odds ratio [OR] = 3.05, confidence interval [CI] 1.29−7.22), fatigue (OR = 2.53, CI 1.11−5.73) and age older than 50 years (OR = 2.23, CI 1.01−4.93).Internal organ involvement is frequent in SS, however there is no significant difference between pSS and sSS concerning its occurrence.","PeriodicalId":94325,"journal":{"name":"JEADV clinical practice","volume":" August","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141823780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Two pemphigoid cases with mucous membrane involvement successfully treated with baricitinib 巴利替尼成功治疗两例粘膜受累的丘疹性荨麻疹病例
JEADV clinical practice Pub Date : 2024-07-19 DOI: 10.1002/jvc2.511
Tamás Malkovics, Orsolya N. Horváth, Miklós Sárdy
{"title":"Two pemphigoid cases with mucous membrane involvement successfully treated with baricitinib","authors":"Tamás Malkovics, Orsolya N. Horváth, Miklós Sárdy","doi":"10.1002/jvc2.511","DOIUrl":"https://doi.org/10.1002/jvc2.511","url":null,"abstract":"Both bullous pemphigoid and mucous membrane pemphigoid are autoimmune bullous diseases that can be challenging to treat in individual cases. Janus kinase inhibitors have shown efficacy in several autoimmune and inflammatory diseases, although these drugs are not yet widely used in autoimmune bullous diseases. We report two recalcitrant cases of pemphigoid with mucous membrane involvement which were successfully treated with the JAK 1/2 inhibitor baricitinib after all other feasible therapeutic options had been exhausted.","PeriodicalId":94325,"journal":{"name":"JEADV clinical practice","volume":" February","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141823934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between pemphigus vulgaris and pyoderma gangrenosum 寻常天疱疮与脓皮病之间的联系
JEADV clinical practice Pub Date : 2024-07-08 DOI: 10.1002/jvc2.507
Ana M. Cano, Valentina Burbano, Ricardo A. Rueda
{"title":"Association between pemphigus vulgaris and pyoderma gangrenosum","authors":"Ana M. Cano,&nbsp;Valentina Burbano,&nbsp;Ricardo A. Rueda","doi":"10.1002/jvc2.507","DOIUrl":"10.1002/jvc2.507","url":null,"abstract":"<p>Pyoderma gangrenosum (PG) is a neutrophilic dermatosis associated with certain neoplasms, predominantly of haematological origin, and autoimmune diseases. Pemphigus vulgaris (PV) is a disease in which antibodies target crucial intercellular junction components. A few cases of PG associated with PV have been described. We present a woman with a high phototype presenting this rare association and highlight the diagnostic challenge of diagnosing rare diseases in patients with high phenotypes.</p>","PeriodicalId":94325,"journal":{"name":"JEADV clinical practice","volume":"3 3","pages":"902-905"},"PeriodicalIF":0.0,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jvc2.507","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141667259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Use of miltefosine in the treatment of cutaneous leishmaniasis in French Guiana 在法属圭亚那使用米替福新治疗皮肤利什曼病
JEADV clinical practice Pub Date : 2024-07-05 DOI: 10.1002/jvc2.400
Charlene Oliveira, Kevin Arrivé, Yannick Andro, Celine Michaud, Kinan Drak Alsibai, Pierre Couppie, Magalie Demar, Romain Blaizot
{"title":"Use of miltefosine in the treatment of cutaneous leishmaniasis in French Guiana","authors":"Charlene Oliveira,&nbsp;Kevin Arrivé,&nbsp;Yannick Andro,&nbsp;Celine Michaud,&nbsp;Kinan Drak Alsibai,&nbsp;Pierre Couppie,&nbsp;Magalie Demar,&nbsp;Romain Blaizot","doi":"10.1002/jvc2.400","DOIUrl":"10.1002/jvc2.400","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Nearly half of the cutaneous leishmaniasis (CL) cases in French Guiana occur in remote rainforest areas. The treatment of pentamidine-resistant strains currently requires hospitalisation for intravenous amphotericin, involving significant indirect costs. Miltefosine is currently the only oral drug available but is only used in French Guiana as a third- or fourth-line treatment under a temporary use authorisation.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>The primary objective of this study was to evaluate the effectiveness of miltefosine in French Guiana. Secondary objectives were to evaluate its safety and acceptability, and patient satisfaction.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The study was carried out at the Cayenne Hospital and remote health centres in French Guiana. All patients with proven CL and treated with miltefosine between 1 January 2017 and 1 April 2022 were included. Cure was defined as complete re-epithelisation with no new lesions at 90 days. Adherence (all doses taken) and side effects were routinely evaluated at the end of treatment. Patients were retrospectively called back to evaluate the impact of CL on their life quality before treatment and their satisfaction with miltefosine.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Fifteen patients were included. The main species was <i>Leishmania guyanensis</i> (<i>n</i> = 9; 60%), followed by <i>L. braziliensis</i> (<i>n</i> = 4; 26.7%). Eight patients (53.3%) were cured. Eleven patients (73.3%) presented adverse effects (mainly digestive), with seven of these (46.7%) requiring therapeutic adaptations. Eight patients demonstrated complete adherence; of these, six (75%) were cured, including six cases of <i>L. guyanensis</i>, one case of <i>L. braziliensis</i> and one <i>Leishmania</i> spp. Most patients (88.9%) were satisfied with the treatment and said they preferred oral administration to the parenteral route.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Miltefosine is a valuable treatment option for CL in French Guiana. The side effects can diminish patient adherence, but its oral administration is associated with high patient satisfaction. A regular marketing authorisation would facilitate its prescription and allow for the creation of larger cohorts.</p>\u0000 </section>\u0000 </div>","PeriodicalId":94325,"journal":{"name":"JEADV clinical practice","volume":"3 3","pages":"850-856"},"PeriodicalIF":0.0,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jvc2.400","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141675924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Itchy vesicles on black skin 黑色皮肤上的瘙痒水泡
JEADV clinical practice Pub Date : 2024-07-05 DOI: 10.1002/jvc2.485
Thomas Akel Oberpaur, Tania M. Capusan, Ana R. Gamero Rodríguez, Iván Rodrigo Díaz, Javier Alcántara González, Marta Ruano Del Salado, Cristian Perna, Carla Rodríguez Naranjo, María Elena Sánchez-Largo Uceda
{"title":"Itchy vesicles on black skin","authors":"Thomas Akel Oberpaur,&nbsp;Tania M. Capusan,&nbsp;Ana R. Gamero Rodríguez,&nbsp;Iván Rodrigo Díaz,&nbsp;Javier Alcántara González,&nbsp;Marta Ruano Del Salado,&nbsp;Cristian Perna,&nbsp;Carla Rodríguez Naranjo,&nbsp;María Elena Sánchez-Largo Uceda","doi":"10.1002/jvc2.485","DOIUrl":"10.1002/jvc2.485","url":null,"abstract":"<p>A 60-year-old black woman from Ghana, who had been residing in Spain for over 20 years, was referred to our clinic after presenting progressively itchy lesions following a unilateral knee replacement surgery 4 months ago. Her medical background was notable for obesity, osteoarthritis, hypertension and hypothyroidism. The patient noted the onset of her symptoms once the postoperative pain had subsided. At first, pruritus and dark macules around the scars were believed to be normal but then continued to develop scaly, and itchy plaques predominantly on the extensor surfaces of both her lower limbs. These plaques gradually progressed to cover her back and trunk, sparing the face and mucous membranes. Her condition had not improved with empiric topical corticosteroids before our evaluation.</p><p>Upon dermatological examination, she exhibited multiple clear vesicles on erosive, pruritic, lichenified and hyperpigmented plaques (Figure 1). These vesicles were noteworthy for not being fragile or entirely flaccid. Certain blood tests were ordered and an intact vesicle and surrounding skin were excised for microscopic investigation (Figure 2).</p><p>PF is a rare subtype of pemphigus, much less frequently encountered than pemphigus vulgaris (PV). It is uncommon globally, with a higher prevalence in endemic areas like Brazil and Africa, more related to geographic and socioeconomic factors rather than ethnicity, age or gender.<span><sup>1</sup></span> The literature on PF cases in individuals from Africa is limited, though there is a noted higher incidence in South Africa<span><sup>2</sup></span> and endemic occurrences in the northern African countries and the Kilimanjaro region<span><sup>3</sup></span> (namely Kenya and Tanzania). Our case exemplifies a sporadic (nonendemic) occurrence of PF, with no related geographical, travel or medication history. Even though triggers are not usually identified, this case seems to have been triggered by the surgery, which has been reported in some other publications.</p><p>PF's typical presentation involves painful scaly, erythematous erosions in seborrheic areas, with intact vesicles being a rare find.<span><sup>4, 5</sup></span> Our case diverges from the norm, as the patient has never noted pain regarding this condition, seborrheic areas are spared at every flare-up and vesicles remain intact for several days. The presence of circulating antibodies targeting Dsg-1, a necessary adhesion molecule in the outer layers of cutaneos epidermis but not indispensable in mucosas, along with preservation of Dsg-3, reflect the physiopathology of this disease and the differences with PV.<span><sup>5</sup></span> Although we cannot establish why the distribution or the symptoms in our case differs from the classic presentation, we can at least hypothesize that the vesicles are less fragile owing to the more compact corneal layer found in black skin.<span><sup>6</sup></span> Interestingly, the notorious postinflammatory hyperpig","PeriodicalId":94325,"journal":{"name":"JEADV clinical practice","volume":"3 3","pages":"934-937"},"PeriodicalIF":0.0,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jvc2.485","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141674064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cutaneous body image in patients with lichen planus: A cross‐sectional study 扁平苔藓患者的皮肤身体形象:横断面研究
JEADV clinical practice Pub Date : 2024-07-02 DOI: 10.1002/jvc2.505
D. Koumaki, S. Gregoriou, Aikaterini Chatziperrou, Georgios Evangelou, Aikaterini Doxastaki, Konstantinos Krasagakis
{"title":"Cutaneous body image in patients with lichen planus: A cross‐sectional study","authors":"D. Koumaki, S. Gregoriou, Aikaterini Chatziperrou, Georgios Evangelou, Aikaterini Doxastaki, Konstantinos Krasagakis","doi":"10.1002/jvc2.505","DOIUrl":"https://doi.org/10.1002/jvc2.505","url":null,"abstract":"","PeriodicalId":94325,"journal":{"name":"JEADV clinical practice","volume":"52 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141838113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Skin diversity and skin of colour 皮肤多样性和有色皮肤
JEADV clinical practice Pub Date : 2024-06-25 DOI: 10.1002/jvc2.496
Nicolas Kluger
{"title":"Skin diversity and skin of colour","authors":"Nicolas Kluger","doi":"10.1002/jvc2.496","DOIUrl":"https://doi.org/10.1002/jvc2.496","url":null,"abstract":"<p><i>Diversity</i> can be defined as ‘all characteristics and experiences that define each of us as individuals’. A common misconception about diversity is that it would only apply to certain persons or groups, while it is the exact opposite. Diversity includes the entire spectrum of primary dimensions of an individual, including ethnicity, gender, age, religion, disability, and sexual orientation. Secondary dimensions commonly include communication style, work style, organizational role/level, economic status, and geographic origin.<span><sup>1</sup></span> How to define <i>skin diversity</i> in this case? It refers to a wide range of variations in human skin, including differences in colour, textures, tones, and so on, considering genetic factors, environmental exposures, and cultural practices. Understanding skin diversity is crucial for fostering inclusivity and providing effective care tailored to the unique needs of individuals.</p><p>For this current special issue on skin diversity of the JEADV Clinical practice, we chose to highlight various aspect around skin of colour (SoC).</p><p>The presentation of many skin diseases on SoC may be different from that seen on light skin. An inexperienced practitioner can quickly be in a situation of failure in consultation. The very first step is to sensitize medical students early in their curriculum to SoC.<span><sup>2, 3</sup></span> Trained residents and graduated practitioners can benefit from university training courses,<span><sup>4</sup></span> lectures, or workshops in meetings or congresses. The increase of specific iconography featuring SoC in medical atlases is warranted.<span><sup>5</sup></span> Proper training will help prevent intellectual biases that are not rare in our experience with patients with SoC.<span><sup>6</sup></span></p><p>The proper knowledge of the basic epidemiology of skin diseases among SoC is also crucial. The pattern of skin diseases a dermatologist encounters is way different whether he is an office-based dermatologist in a capital of a Western country, a practitioner working closely with immigrants or refugees that have recently arrived in the country<span><sup>7</sup></span> or directly in Africa<span><sup>8</sup></span> or South America.<span><sup>9</sup></span></p><p>A review by Nadège Cordel summarizes the clinical presentation of systemic diseases in Afro-Caribbean patients,<span><sup>10</sup></span> while several case reports illustrate some conditions that are specific for SoC.<span><sup>11, 12</sup></span></p><p>Lastly, the review by Schuster et al. about the efficacy of of Isobutylamido-Thiazolyl-Resorcinol on hyperpigmentation of the skin<span><sup>13</sup></span> reminds us that postinflammatory pigmentation and hyperpigmentation in general are frequent and disabling symptoms in persons of colour.</p><p>The wide spectrum of topics covered in this special issue of the JEADV clinical practice illustrates how vast the field of skin of colour dermatology is.<","PeriodicalId":94325,"journal":{"name":"JEADV clinical practice","volume":"3 3","pages":"793-794"},"PeriodicalIF":0.0,"publicationDate":"2024-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jvc2.496","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141730361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Photoprotective behaviours amongst persons with albinism in Uyo, Nigeria 尼日利亚乌约白化病患者的防晒行为
JEADV clinical practice Pub Date : 2024-06-14 DOI: 10.1002/jvc2.482
Edesiri E. Ighorodje, Charles N. Nga, Chinyere C. Atansi, Omolara Y. Ukpong, Morolayo O. Fabiyi, Udeme-Abasi U. Nelson
{"title":"Photoprotective behaviours amongst persons with albinism in Uyo, Nigeria","authors":"Edesiri E. Ighorodje,&nbsp;Charles N. Nga,&nbsp;Chinyere C. Atansi,&nbsp;Omolara Y. Ukpong,&nbsp;Morolayo O. Fabiyi,&nbsp;Udeme-Abasi U. Nelson","doi":"10.1002/jvc2.482","DOIUrl":"10.1002/jvc2.482","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Strict photoprotection is crucial for persons living with albinism (PWAs), especially in Nigeria where the level of solar ultraviolet radiation is particularly high, which further increases the susceptibility of this population to develop photodermatoses and, ultimately, skin cancer.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>This study aimed to assess the knowledge and attitude towards photoprotection among PWAs in Uyo, Akwa Ibom, Nigeria.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A descriptive cross-sectional study involving consenting 50 participants with oculocutaneous albinism was recruited through interviewer-administered questionnaires. Data analysis utilised SPSS 26.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The use of sun-protective clothing was the predominant photoprotective measure (62%) with an overall low sun-protection strategy usage of 5% and 10% knowledge rate, despite 80% acknowledging the daily use of various forms of photoprotection. Cost was cited as the commonest deterrent to poor use of sunscreen (47.8%).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Poor awareness and photoprotection usage amongst persons with albinism in Uyo are discouragingly below standard increasing their risk of developing photodermatoses which adversely affects their quality of life. Therefore, dermatologists should improve collaborative efforts at addressing barriers such as cost and enhancing knowledge about effective photoprotection strategies.</p>\u0000 </section>\u0000 </div>","PeriodicalId":94325,"journal":{"name":"JEADV clinical practice","volume":"3 3","pages":"876-881"},"PeriodicalIF":0.0,"publicationDate":"2024-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jvc2.482","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141343668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An insight into racial bias in dermoscopy repositories: A HAM10000 data set analysis 洞察皮肤镜资料库中的种族偏见:HAM10000 数据集分析
JEADV clinical practice Pub Date : 2024-06-14 DOI: 10.1002/jvc2.477
Andres Morales-Forero, Lili Rueda Jaime, Sebastian Ramiro Gil-Quiñones, Marlon Y. Barrera Montañez, Samuel Bassetto, Eric Coatanea
{"title":"An insight into racial bias in dermoscopy repositories: A HAM10000 data set analysis","authors":"Andres Morales-Forero,&nbsp;Lili Rueda Jaime,&nbsp;Sebastian Ramiro Gil-Quiñones,&nbsp;Marlon Y. Barrera Montañez,&nbsp;Samuel Bassetto,&nbsp;Eric Coatanea","doi":"10.1002/jvc2.477","DOIUrl":"10.1002/jvc2.477","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Studies have revealed a lack of representation of skin of colour patients in academic sources of dermatologic diseases, including databases. This visual racism has consequently generated less comfort and confidence among the specialists in the care and attention of this ethnic group, including the opportunity of being correctly diagnosed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To investigate and uncover potential racial biases in the HAM10000 data set through an exploratory analysis of the dark skin tones representation, the identification of inaccuracies in its documentation, the recognition of relevant skin conditions absent for darker skin and the lack of ethnic diversity variables crucial for validating diagnosis across different skin tones.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>An exploratory examination was conducted to investigate the occurrence of dark skin within the HAM10000 database (housed in a Harvard Dataverse repository), consisting of 10,015 dermoscopic images of skin lesions. A visual depiction encompassing the whole skin tones was generated by sampling four crucial data points from each image and applying the Gray World Algorithm for colour normalization. To confirm the accuracy of the graphical representation, dermatologists validated the pixel sampling process by analysing a randomly selected 10% of the images for each type of skin lesion. This visual representation was produced for the entire data set as well as for each skin lesion type. The study was further enhanced by comparing the skin lesion representation within the HAM10000 data set against documented prevalences of relevant conditions affecting dark skin.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Less than 5% of the images came from dark-skinned patients. Nevertheless, in about 4.9% of cases, our pixel sampling method might inadvertently capture shadows or dark spots resulting from the imaging device or the lesion itself rather than the individual's actual skin tone. In addition, there are inaccuracies in the data set's claims of diversity and comprehensive coverage, notably the underrepresentation of conditions prevalent in darker skin and the absence of ethnic diversity variables.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Visual racism is an issue that needs to be addressed in medical sources of information and education. Image databases and artificial intelligence models need to be nourished with ","PeriodicalId":94325,"journal":{"name":"JEADV clinical practice","volume":"3 3","pages":"836-843"},"PeriodicalIF":0.0,"publicationDate":"2024-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jvc2.477","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141343382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信