International journal of medicinal mushrooms最新文献_第9页

Enhanced Yield of Bioactive Compounds and Antioxidant Activities in Four Fermented Beans of Phellinus linteus Strains (Agaricomycetes) by Solid-State Fermentation. 用固态发酵法提高四株黄曲霉发酵豆中生物活性物质的产量和抗氧化活性。

International journal of medicinal mushrooms Pub Date : 2023-01-01 DOI: 10.1615/IntJMedMushrooms.2023049500

Yu-Li Lin, Meng-Yen Lin, Chih-Hung Liang, Chiu-Yeh Wu, Po-Hsien Li, Zeng-Chin Liang

{"title":"Enhanced Yield of Bioactive Compounds and Antioxidant Activities in Four Fermented Beans of Phellinus linteus Strains (Agaricomycetes) by Solid-State Fermentation.","authors":"Yu-Li Lin, Meng-Yen Lin, Chih-Hung Liang, Chiu-Yeh Wu, Po-Hsien Li, Zeng-Chin Liang","doi":"10.1615/IntJMedMushrooms.2023049500","DOIUrl":"10.1615/IntJMedMushrooms.2023049500","url":null,"abstract":"Phellinus linteus is a famous medicinal mushroom which exhibits various biological activities. This study aimed to investigate the effects of solid-state fermentation by Ph. linteus on the yield of bioactive compounds and antioxidant activities of beans. Four bean substrates were prepared and inoculated with inoculum of three strains of Ph. linteus, respectively. During the cultivation, the harvested samples were dried, grounded, extracted, and determined the contents of bioactive compounds and antioxidant activities. The results indicated that the mung bean fermented by Ph. linteus 04 had the highest polysaccharide content (98.8 mg/g). The highest total phenolic and flavonoid contents were in fermented soybeans by Ph. linteus 03 (15.03 mg gallic acid equivalents/g and 63.24 mg rutin equivalents/g, respectively). The 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) radical scavenging activities of hot water extracts were higher than those of ethanolic extracts for fermented beans by three Ph. linteus strains. However, the superoxide anion radical scavenging ability of ethanolic extracts was higher than those of hot water extracts in the fermented beans of the three strains. The ferrous ion (Fe2+)-chelating abilities of hot water extracts were higher than those of ethanolic extracts in fermented beans by Ph. linteus 03 and 04. In contrast, ethanolic extracts were higher than hot water extracts in fermented beans by Ph. linteus 06. Overall, these results indicate that the fermentation by Ph. linteus strains increased the bioactive compounds and antioxidant activities of four beans.","PeriodicalId":94323,"journal":{"name":"International journal of medicinal mushrooms","volume":"25 9","pages":"43-61"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41224767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chaga Medicinal Mushroom, Inonotus obliquus (Agaricomycetes), Polysaccharides Alleviate Photoaging by Regulating Nrf2 Pathway and Autophagy. Chaga药用蘑菇，Inonotus oblitus（蘑菇门），多糖通过调节Nrf2通路和自噬来减缓光老化。

International journal of medicinal mushrooms Pub Date : 2023-01-01 DOI: 10.1615/IntJMedMushrooms.2023049657

Jun Lin, Yin-Ying Lu, Hong-Yu Shi, Pei Lin

{"title":"Chaga Medicinal Mushroom, Inonotus obliquus (Agaricomycetes), Polysaccharides Alleviate Photoaging by Regulating Nrf2 Pathway and Autophagy.","authors":"Jun Lin, Yin-Ying Lu, Hong-Yu Shi, Pei Lin","doi":"10.1615/IntJMedMushrooms.2023049657","DOIUrl":"10.1615/IntJMedMushrooms.2023049657","url":null,"abstract":"Inonotus obliquus is a medicinal mushroom that contains the valuable I. obliquus polysaccharides (IOP), which is known for its bioactive properties. Studies have shown that IOP could inhibit oxidative stress induced premature aging and DNA damage, and delay body aging. However, the molecular mechanism of IOP in improving skin photoaging remains unclear, which prevents the development and utilization of I. obliquus in the field of skin care. In this study, ultraviolet B (UVB) induced human immortalized keratinocyte (HaCaT) cell photoaging model was used to explore the mechanism of IOP in relieving skin photoaging. Results showed that IOP inhibited cell senescence and apoptosis by reducing the protein expressions of p16, p21, and p53. IOP increased HO-1, SOD, and CAT expressions to achieve Nrf2/HO-1 pathway, thus improving antioxidant effects and preventing ROS generation. Furthermore, IOP enhanced the expression levels of p-AMPK, LC3B, and Beclin-1 to alleviate the autophagy inhibition in UVB-induced HaCaT cells. Based on these findings, our data suggested that IOP may be used to develop effective natural anti-photoaging ingredients to promote skin health.","PeriodicalId":94323,"journal":{"name":"International journal of medicinal mushrooms","volume":"25 10","pages":"49-64"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41224780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Oral Lingzhi or Reishi Medicinal Mushroom Ganoderma lucidum (Agaricomycetes) Spore Powder Ameliorates Murine Colitis by Inhibiting Key Kinases Phosphorylation in MAPK Pathway. 口服灵芝或灵芝药用蘑菇灵芝孢子粉通过抑制MAPK途径中的关键激酶磷酸化来改善小鼠结肠炎。

International journal of medicinal mushrooms Pub Date : 2023-01-01 DOI: 10.1615/IntJMedMushrooms.2023049699

Yingying Zhao, Liangchen Zhu

{"title":"Oral Lingzhi or Reishi Medicinal Mushroom Ganoderma lucidum (Agaricomycetes) Spore Powder Ameliorates Murine Colitis by Inhibiting Key Kinases Phosphorylation in MAPK Pathway.","authors":"Yingying Zhao, Liangchen Zhu","doi":"10.1615/IntJMedMushrooms.2023049699","DOIUrl":"10.1615/IntJMedMushrooms.2023049699","url":null,"abstract":"The compound ganoderma lucidum spore powder (GLSP) has emerged as an anti-inflammatory and anti-oxidative regulator. In this study, we explored the roles of GLSP against dextran sulfate sodium (DSS)-induced mouse colitis that can mimic human inflammatory bowel disease (IBD). GLSP was administered by oral gavage at a dosage of 150 mg/kg/day to the acute colitis mice induced by DSS. The DSS-induced mouse weight loss, colonic shortening, diarrhea and bloody stool were observably alleviated after GLSP treatment. The lesion of macroscopic and microscopic signs of the disease was reduced significantly and DSS-induced gut barrier dysfunction was restored via increasing the level of claudin-1, ZO1, Occu, and ZO2 with GLSP. Meanwhile, the levels of IL-6, TNF-α, IL-1β, and IL-18 in the colon were reduced in the GLSP-treated groups. In addition, phosphorylation of the MAPKs ERK1/2, p38, and AKT was suppressed after GLSP treatment. All these results demonstrated that GLSP owned a protective effect on DSS-induced colitis by inhibition of MAPK pathway, which provides a promising therapeutic approach for the treatment of colitis.","PeriodicalId":94323,"journal":{"name":"International journal of medicinal mushrooms","volume":"25 10","pages":"39-48"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41224782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Brown Slime Cap Mushroom (Chroogomphus rutilus, Agaricomycetes) Polysaccharide Resists Motion Sickness by Inhibiting the Activity of the Serotonin System in Mice. 褐藻多糖通过抑制小鼠血清素系统的活性来抵抗运动病。

International journal of medicinal mushrooms Pub Date : 2023-01-01 DOI: 10.1615/IntJMedMushrooms.2023050471

Tao Zhang, Tianyuan Guan, Hui Yao, Li-An Wang, Yanqin Wang, Zhenlong Guan

{"title":"Brown Slime Cap Mushroom (Chroogomphus rutilus, Agaricomycetes) Polysaccharide Resists Motion Sickness by Inhibiting the Activity of the Serotonin System in Mice.","authors":"Tao Zhang, Tianyuan Guan, Hui Yao, Li-An Wang, Yanqin Wang, Zhenlong Guan","doi":"10.1615/IntJMedMushrooms.2023050471","DOIUrl":"10.1615/IntJMedMushrooms.2023050471","url":null,"abstract":"Motion sickness (MS) is a disorder of the autonomic nervous system caused by abnormal exercise with symptoms such as nausea, vomiting and drowsiness. More than 90% of the human population has experienced different degrees of MS. At present, anticholinergics, antihistamines, and sympathomimetic drugs are used for treating MS, but these drugs generally have some adverse reactions and are not suitable for all people. Therefore, it is necessary to develop anti-MS drugs that have high efficiency and no adverse effects. Previous studies have found that Chroogomphus rutilus polysaccharide (CRP) is effective at preventing and treating MS in rats and mice. However, its mechanism of action is not clear. To clarify whether the CRP has anti-MS effects in mice, and to clarify its mechanism, we performed behavioral, biochemical, and morphological tests in a Kunming mouse model. Our results indicate that CRPs can significantly relieve the symptoms of MS, and their effect is equivalent to that of scopolamine, a commonly used anti-MS medicine. Our results indicate that CRPs may directly act on the gastrointestinal chromaffin cells to inhibit the synthesis and release of serotonin (5-hydroxytryptamine, or 5-HT) and thus reduce the signal from the gastrointestinal tract.","PeriodicalId":94323,"journal":{"name":"International journal of medicinal mushrooms","volume":"25 12","pages":"1-13"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72016570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Polyacetylene Derivatives from the Polypore Fungus (Fistulina hepatica, Agaricomycetes) and Their Antimicrobial Activity. 多孔菌（Fistulina hepatica，Agariicomyces）的聚乙炔衍生物及其抗菌活性。

International journal of medicinal mushrooms Pub Date : 2023-01-01 DOI: 10.1615/IntJMedMushrooms.2023050525

Anastasiia O Whaley, Andrei K Whaley, Anastasia A Orlova, Sergey V Volobuev, Natalia V Shakhova, Sergey N Smirnov, Natalia V Pustovit, Liudmila A Kraeva

引用次数: 0

Antioxidative and Antibacterial Hydro-Ethanolic Fraction from an Asian Edible Mushroom Lentinus sajor-caju (Agaricomycetes) Suppresses Inflammatory Responses by Downregulating COX-2 and iNOS Expression 亚洲食用菌香菇的抗氧化和抗菌水解乙醇组分通过下调COX-2和iNOS的表达抑制炎症反应

International journal of medicinal mushrooms Pub Date : 2023-01-01 DOI: 10.1615/intjmedmushrooms.2023051138

Arghya Naskar, Adhiraj Dasgupta, Gouri Basak, KRISHNENDU ACHARYA

{"title":"Antioxidative and Antibacterial Hydro-Ethanolic Fraction from an Asian Edible Mushroom Lentinus sajor-caju (Agaricomycetes) Suppresses Inflammatory Responses by Downregulating COX-2 and iNOS Expression","authors":"Arghya Naskar, Adhiraj Dasgupta, Gouri Basak, KRISHNENDU ACHARYA","doi":"10.1615/intjmedmushrooms.2023051138","DOIUrl":"https://doi.org/10.1615/intjmedmushrooms.2023051138","url":null,"abstract":"Mushrooms are prevalently important sources of pharmaceutically active metabolites. Various mushroom species belonging to the Lentinus genus are recognized for their nutritional and therapeutic properties. One such species is L. sajor-caju, which is renowned in Southeast Asian nations for its culinary value. The primary goal of this study is to investigate the potential medicinal properties of L. sajor-caju, specifically its antioxidant, antibacterial, and anti-inflammatory effects. A hydroethanolic extract was formulated using dried basidiocarps, which exhibited a high phenolic content of approximately 14 % and a flavonoid content of approximately 2.7 %. The extract demonstrated significant antioxidant potential in in-vitro reactions. The extract is sufficiently capable of scavenging free radicals (DPPH and ABTS) and chelate Fe2+ with EC50 values spanning from 186 to 390 μg/mL. Besides, considerable antimicrobial activity against tested pathogenic microorganisms was observed, as indicated by low MIC50 values (256-358 μg/ml). Moreover, the fraction was found to prevent heat-induced protein denaturation which signifies its anti-inflammatory potential. When tested on the RAW 264.7 cell line, reduction in the nitrite production, and downregulation of COX-2 and iNOS mRNA expression was observed which are the key regulator of inflammatory signalling systems. The study, therefore, recommends the use of L. sajor-caju in the medical and pharmaceutical industries for the benefit of humanity.","PeriodicalId":94323,"journal":{"name":"International journal of medicinal mushrooms","volume":"364 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136209812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antimicrobial Activities of Ganoderma mbrekobenum Strain EGDA (Agaricomycetes) from Egypt. 埃及伞状灵芝菌株EGDA的抗菌活性。

International journal of medicinal mushrooms Pub Date : 2023-01-01 DOI: 10.1615/IntJMedMushrooms.2023049502

Mahmoud M Nour El-Dein, Amira A El-Fallal, Ahmed K A El-Sayed, Shimaa R El-Esseily

引用次数: 0

Bioactivities and Medicinal Value of the Fruiting Bodies Extracts of Laetiporus sulphureus and Meripilus giganteus Polypore Mushrooms (Agaricomycetes) 硫酸松菇和巨穗多孔菇子实体提取物的生物活性及药用价值

International journal of medicinal mushrooms Pub Date : 2023-01-01 DOI: 10.1615/intjmedmushrooms.2023051297

Marijana Kosanić, Nevena Petrovic, Dragana Šeklić, Marko Živanović, Mihajlo Kokanović

引用次数: 0

Advances in Mechanism and Application of Molecular Breeding of Medicinal Mushrooms: A Review. 药用蘑菇分子育种机理及应用研究进展。

International journal of medicinal mushrooms Pub Date : 2023-01-01 DOI: 10.1615/IntJMedMushrooms.2023050122

Wenming Jiang, Jing Wang, Hongyu Pan, Rui Yang, Feifei Ma, Jiahao Luo, Chunchao Han

引用次数: 0

Interactive Effects of Selenium, Zinc, and Iron on the Uptake of Selenium in Mycelia of the Culinary-Medicinal Winter Mushroom Flammulina velutipes (Agaricomycetes). 硒、锌、铁对冬菇菌丝体硒吸收的交互作用。

International journal of medicinal mushrooms Pub Date : 2023-01-01 DOI: 10.1615/IntJMedMushrooms.2023050153

Rezvan Ramezannejad, Hamid R Pourianfar, Sharareh Rezaeian

{"title":"Interactive Effects of Selenium, Zinc, and Iron on the Uptake of Selenium in Mycelia of the Culinary-Medicinal Winter Mushroom Flammulina velutipes (Agaricomycetes).","authors":"Rezvan Ramezannejad, Hamid R Pourianfar, Sharareh Rezaeian","doi":"10.1615/IntJMedMushrooms.2023050153","DOIUrl":"10.1615/IntJMedMushrooms.2023050153","url":null,"abstract":"The present study for the first time addressed whether the simultaneous presence of selenium, zinc and iron may have effects on the selenium uptake in the mycelia of the winter mushroom (also known as enoki), Flammulina velutipes. Response surface methodology was used to optimize concentrations of selenium, zinc and iron in the range of 0 to 120 mg L-1. The findings showed that application of selenium, zinc and iron (singly, in pairs, or triads) significantly enhanced the selenium accumulation in the mycelia. The highest amount of the selenium accumulation was observed when selenium (60 mg L-1) and zinc (120 mg L-1) were applied into submerged culture media, concurrently, leading to an 85-fold and 88-fold increase in the selenium content of the mycelia compared to that of the mycelia treated with selenium only and untreated mycelia, respectively. In addition, accumulation of selenium into the mycelia had no deteriorative effects on the mycelial biomass. The findings presented in this study may have implications for daily nutrition and industrial bioproduction of mushroom mycelia enriched with selenium.","PeriodicalId":94323,"journal":{"name":"International journal of medicinal mushrooms","volume":"25 11","pages":"75-87"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41224774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0