Asian journal of neurosurgery最新文献

筛选
英文 中文
The Impact of the Pandemic of COVID-19 on the Head Injury Fast-Track System and Surgical Outcome. COVID-19 大流行对头部创伤快速通道系统和手术结果的影响。
Asian journal of neurosurgery Pub Date : 2024-09-30 eCollection Date: 2024-12-01 DOI: 10.1055/s-0044-1791267
Thunya Norasethada, Kriengsak Limpastan, Tanat Vaniyapong, Wanarak Watcharasaksilp, Chumpon Jetjumnong, Chanon Srihagulang, Thanat Kanthawang, Todsapon Praphanuwat, Withawat Vuthiwong, Jirapong Vongsfak
{"title":"The Impact of the Pandemic of COVID-19 on the Head Injury Fast-Track System and Surgical Outcome.","authors":"Thunya Norasethada, Kriengsak Limpastan, Tanat Vaniyapong, Wanarak Watcharasaksilp, Chumpon Jetjumnong, Chanon Srihagulang, Thanat Kanthawang, Todsapon Praphanuwat, Withawat Vuthiwong, Jirapong Vongsfak","doi":"10.1055/s-0044-1791267","DOIUrl":"10.1055/s-0044-1791267","url":null,"abstract":"<p><p><b>Objective</b>  This study aims to evaluate the impact of the coronavirus disease 2019 (COVID-19) pandemic on the head injury fast-track system and surgical treatment outcomes. <b>Materials and Methods</b>  A retrospective review was conducted on patients who underwent emergency neurological procedures according to the head injury fast-track system. Data from April 2018 to April 2020 (pre-COVID) were compared with data from May 2020 to May 2022 (during COVID). <b>Results</b>  The analysis comprised 128 patients in the prepandemic group and 119 patients in the pandemic group, with 5 patients diagnosed with COVID infection during the pandemic. Acute subdural hematoma resulting from motorcycle accidents was the most common diagnosis in both groups (56.3 and 47.5%, respectively). The initial Glasgow coma scale (GCS) score was significantly lower during the pandemic compared to the prepandemic period ( <i>p</i>  = 0.025). Time metrics in the emergency department, including door to computed tomography (CT), emergency room (ER) exit, and incision times, were significantly longer in the pandemic group ( <i>p</i>  < 0.05). However, there were no statistically significant differences in in-hospital mortality rates (25.8 and 17.7%, respectively; <i>p</i>  = 0.12) or the percentage of patients with a favorable functional outcome (Glasgow outcome scale ≥4). At 1 month, a favorable functional outcome was observed in 51.6% of prepandemic patients and 57.1% of pandemic patients ( <i>p</i>  = 0.69), while at 6 months, the percentages were 56.8 and 64.5%, respectively ( <i>p</i>  = 0.23). <b>Conclusions</b>  Our study revealed significant delays in hospital processes for head injuries during the COVID-19 pandemic. However, we found no significant impact on mortality rates or functional outcomes of patients.</p>","PeriodicalId":94300,"journal":{"name":"Asian journal of neurosurgery","volume":"19 4","pages":"753-759"},"PeriodicalIF":0.0,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11588609/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142741954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evolution of Robotics in Neurosurgery. 神经外科机器人技术的发展。
Asian journal of neurosurgery Pub Date : 2024-09-27 eCollection Date: 2024-12-01 DOI: 10.1055/s-0044-1790606
Salman T Shaikh, T A Dwarakanath, Aliasgar V Moiyadi
{"title":"Evolution of Robotics in Neurosurgery.","authors":"Salman T Shaikh, T A Dwarakanath, Aliasgar V Moiyadi","doi":"10.1055/s-0044-1790606","DOIUrl":"10.1055/s-0044-1790606","url":null,"abstract":"<p><p>Technology and neurosurgery have gone hand in hand since a long time. Technological development of robotics in neurosurgery over the last couple of decades has been rapid, yet it still has a long way to go before it becomes a \"routine\" element of the standard neurosurgical procedure. Apart from the obvious advantages they have over humans, that is, precision, consistency, endurance, and reproducibility, robots also provide additional freedom of movement beyond what is anatomically feasible for humans. Since its first practical application in 1985, the promise of robotics has spurred development and design of numerous such devices for application in neurosurgery. In the current era, the role of robots in neurosurgery is limited to programming movements and planning trajectories for deep cranial targets, biopsies, spinal screw placements, deep brain stimulation, and stereotactic radiosurgery. This narrative, nonsystematic review discusses the evolution of various robotic systems, with a focus on their neurosurgical applications.</p>","PeriodicalId":94300,"journal":{"name":"Asian journal of neurosurgery","volume":"19 4","pages":"598-609"},"PeriodicalIF":0.0,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11588608/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142741995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy of Ketamine as an Adjuvant to Scalp Block for Hemodynamic Stability in Patients Undergoing Elective Craniotomy for Supratentorial Glioma: A Prospective Randomized Controlled Trial. 氯胺酮作为头皮阻滞的辅助药物对稳定因脑室上胶质瘤而接受开颅手术的患者血流动力学的效果:前瞻性随机对照试验》。
Asian journal of neurosurgery Pub Date : 2024-09-27 eCollection Date: 2024-12-01 DOI: 10.1055/s-0044-1791269
Ashutosh Kaushal, Sharmishtha Pathak, Priyanka Gupta, Praveen Talwar, Anuj Jain, Sunaina Tejpal Karna
{"title":"Efficacy of Ketamine as an Adjuvant to Scalp Block for Hemodynamic Stability in Patients Undergoing Elective Craniotomy for Supratentorial Glioma: A Prospective Randomized Controlled Trial.","authors":"Ashutosh Kaushal, Sharmishtha Pathak, Priyanka Gupta, Praveen Talwar, Anuj Jain, Sunaina Tejpal Karna","doi":"10.1055/s-0044-1791269","DOIUrl":"10.1055/s-0044-1791269","url":null,"abstract":"<p><p><b>Introduction</b>  Scalp nerve block (SNB) attenuates the hemodynamic response to pin insertion and delivers excellent postoperative analgesia. This study aimed to evaluate the efficacy of SNB using ketamine as an adjuvant to bupivacaine on perioperative hemodynamic responses and postoperative pain in patients undergoing craniotomy for supratentorial glioma. <b>Materials and Methods</b>  Sixty patients were randomized into two groups. They were given scalp nerve block either with bupivacaine and saline (group S) or bupivacaine and ketamine (group K). Primary outcome was to compare the change in mean arterial pressure (MAP) and heart rate (HR) at defined time points from baseline. Secondary outcomes included time to request for first analgesia, total analgesic consumption in intraoperative and postoperative periods till 24 hours, and numeric rating scale pain score at various time points in postoperative period till 24 hours. <b>Results</b>  Fifty-seven patients were included in analysis. HR and MAP were comparable intraoperatively till closure. As soon as closure began, a significant increase in HR (group K vs. group S, 69.76 ± 9.03 vs. 93.96 ± 9.98, <i>p</i> -value = < 0.0001) and MAP (group K vs. group S, 79.4 ± 4.12 vs. 87.17 ± 12.67, <i>p</i> -value = 0.002) was noted in group S patients. This increase persisted in the postoperative period as well. The median total opioid consumed during intraoperative period in group K was 200 mcg versus 300 mcg in group S, <i>p</i> -value < 0.0001. <b>Conclusion</b>  Adding ketamine as an adjuvant to bupivacaine for SNB not only provides significant hemodynamic stability but also reduces both intra- and postoperative analgesic consumption.</p>","PeriodicalId":94300,"journal":{"name":"Asian journal of neurosurgery","volume":"19 4","pages":"760-766"},"PeriodicalIF":0.0,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11588621/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142741955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Successful Microsurgical Clipping under Extracorporeal Membrane Oxygenation Treatment for a Poor-Grade Subarachnoid Hemorrhage Patient with Severe Pulmonary Neurogenic Lung. 体外膜氧合治疗下的显微外科夹闭手术成功救治一名重度肺神经源性蛛网膜下腔出血患者
Asian journal of neurosurgery Pub Date : 2024-09-19 eCollection Date: 2024-12-01 DOI: 10.1055/s-0044-1791189
Katsuya Saito, Shoko Ito, Takahiro Miyata, Keita Mayanagi, Joji Inamasu, Masashi Nakatsukasa
{"title":"Successful Microsurgical Clipping under Extracorporeal Membrane Oxygenation Treatment for a Poor-Grade Subarachnoid Hemorrhage Patient with Severe Pulmonary Neurogenic Lung.","authors":"Katsuya Saito, Shoko Ito, Takahiro Miyata, Keita Mayanagi, Joji Inamasu, Masashi Nakatsukasa","doi":"10.1055/s-0044-1791189","DOIUrl":"10.1055/s-0044-1791189","url":null,"abstract":"<p><p>Hemorrhagic strokes are considered as contraindications of extracorporeal membrane oxygenation (ECMO) therapy because of anticoagulant administration and ECMO-associated coagulopathy. We present a rare case of successful microsurgical clipping under ECMO for a poor-grade subarachnoid hemorrhage (SAH) patient with severe neurogenic pulmonary edema (NPE). A 50-year-old man presenting with the sudden loss of consciousness was diagnosed with poor-grade SAH with severe NPE, and was intubated. Because of severe hypoxemia refractory to conventional treatment, venovenous ECMO was used 6 hours after admission. To avoid thrombosis inside the ECMO circuit despite no anticoagulants, a heparin-bonded ECMO was maintained at a comparatively high blood flow rate. Subsequently, the patient underwent a microsurgical clipping under ECMO. Intraoperatively we had difficulty in bleeding control, and therefore the multiple transfusions were necessary to correct anemia and ECMO-associated coagulopathy. The aneurysmal clipping was accomplished without hemorrhagic intracranial complications. After 2 years from onset, his activities of daily life were independent. To our knowledge, this is the first report of successful microsurgical clipping for poor-grade SAH under ECMO without any anticoagulants. The use of a heparin-bonded ECMO tubing, maintenance of a slightly higher ECMO pump speed, and multiple transfusions to correct ECMO-associated coagulopathy could make the micro-neurosurgical procedures under ECMO possible. This report demonstrated the possibility to extend the range of application of microsurgical clipping for poor-grade SAH patients requiring ECMO treatment.</p>","PeriodicalId":94300,"journal":{"name":"Asian journal of neurosurgery","volume":"19 4","pages":"812-815"},"PeriodicalIF":0.0,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11588602/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142741947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sheep Head Cadaveric Model for the Transmeatal Extensions of the Retrosigmoid Approach. 羊头尸体模型用于经阴道延伸的后穹隆入路。
Asian journal of neurosurgery Pub Date : 2024-09-17 eCollection Date: 2024-12-01 DOI: 10.1055/s-0044-1790517
Dmitriy Sergeyevich Korotkov, Alexander Feliciano Paitán, Arevik Abramyan, Feres Eduardo Aparecido Chaddad Neto
{"title":"Sheep Head Cadaveric Model for the Transmeatal Extensions of the Retrosigmoid Approach.","authors":"Dmitriy Sergeyevich Korotkov, Alexander Feliciano Paitán, Arevik Abramyan, Feres Eduardo Aparecido Chaddad Neto","doi":"10.1055/s-0044-1790517","DOIUrl":"10.1055/s-0044-1790517","url":null,"abstract":"<p><p>The transmeatal extension of the retrosigmoid approach is an important procedure used in the treatment of various pathologies affecting the posterior fossa, petroclival region, and jugular foramen. Mastering this technique requires a high level of manual skill, particularly in temporal bone drilling. The objective of this study was to describe an easily accessible and cost-effective model of the transmeatal extension of the retrosigmoid approach using cadaveric sheep heads. Five cadaveric sheep heads, fixed in alcohol and formalin with intravascular-colored silicone injection, were prepared for this study. Two heads (four sides) were designated for illustrative anatomical specimens, while three heads (six sides) were used for surgical simulation. Additionally, one head was used to prepare and dissect a dry skull. All critical steps of the transmeatal approach, including both supra- and inframeatal extensions, were successfully replicated on the model. A comparative anatomical analysis was conducted, focusing on the technical nuances of the model. The cadaveric sheep head serves as an effective model for the retrosigmoid approach with transmeatal extensions, primarily for training manual haptic skills. While the sheep model cannot precisely replicate human anatomy, it still offers valuable training opportunities for neurosurgeons, particularly when human cadaveric specimens are unavailable.</p>","PeriodicalId":94300,"journal":{"name":"Asian journal of neurosurgery","volume":"19 4","pages":"791-804"},"PeriodicalIF":0.0,"publicationDate":"2024-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11588626/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142741944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perioperative Complications of Oblique Lumbar Interbody Fusion (OLIF): 5 Years of Experience with OLIF. 斜行腰椎椎间融合术(OLIF)围手术期并发症:5年的OLIF经验。
Asian journal of neurosurgery Pub Date : 2024-09-11 eCollection Date: 2024-12-01 DOI: 10.1055/s-0044-1790515
Alex T Johnson, Ganesh Kumar, Bibhudendu Mohapatra, Rajat Mahajan
{"title":"Perioperative Complications of Oblique Lumbar Interbody Fusion (OLIF): 5 Years of Experience with OLIF.","authors":"Alex T Johnson, Ganesh Kumar, Bibhudendu Mohapatra, Rajat Mahajan","doi":"10.1055/s-0044-1790515","DOIUrl":"10.1055/s-0044-1790515","url":null,"abstract":"<p><p><b>Objective</b>  The objective of this study was to share our early experience with oblique lumbar interbody fusion (OLIF), with emphasis on the perioperative complications and determine clinical outcomes following OLIF. <b>Materials and Methods</b>  It was a retrospective prospective study performed at a single institute from March 2019 to August 2023. A total of 56 consecutive patients who had undergone OLIF for degenerative spine disorders were enrolled in the study. Pre-, intra-, and postoperative data on these patients were collected. All the patients were followed up at regular intervals with an evaluation of Visual Analog Scale (VAS), Oswestry Disability Index (ODI), neurological parameters, and X-rays to look for fusion, screw loosening, pseudoarthrosis, and cage slippage. Statistical analysis was done with the odds ratio, chi-square test, and Student's <i>t</i> -test. A <i>p-</i> value of < 0.05 was considered significant. <b>Results</b>  The overall incidence of complications was 25%, with no mortality. Intraoperative complications were noted in 10.7% of cases. This included endplate fractures ( <i>n</i>  = 3), peritoneal lacerations ( <i>n</i>  = 2), and ureteric injury ( <i>n</i>  = 1). The most common early postoperative complications were postoperative ileus ( <i>n</i>  = 6), followed by anterior thigh or groin numbness ( <i>n</i>  = 3), ipsilateral psoas weakness ( <i>n</i>  = 2), and superficial surgical site infection ( <i>n</i>  = 2). Of the late postoperative complications, cage subsidence was the most common, which occurred in 4 patients, followed by adjacent segment degeneration ( <i>n</i>  = 2) and loss of indirect decompression ( <i>n</i>  = 1). The mean ODI and VAS scores showed significant improvement ( <i>p</i>  < 0.05) at the final follow-up. <b>Conclusion</b>  OLIF is a promising surgical technique with the potential to treat a variety of degenerative conditions of the lumbar spine with a good clinical outcome. Despite its various benefits, OLIF can lead to complications in rare instances, which every spine surgeon should be aware of.</p>","PeriodicalId":94300,"journal":{"name":"Asian journal of neurosurgery","volume":"19 4","pages":"721-727"},"PeriodicalIF":0.0,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11588599/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142741659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Superior Cerebellar Artery Aneurysm in a Case of Moyamoya Disease: A Rare Entity. 莫亚莫亚氏病病例中的小脑上动脉瘤:罕见病例。
Asian journal of neurosurgery Pub Date : 2024-09-10 eCollection Date: 2024-12-01 DOI: 10.1055/s-0044-1790518
Krushikumar B Soladhra, Arvindkumar Verma, Varshesh K Shah, Dharmikkumar K Velani, Jaimin Modh
{"title":"Superior Cerebellar Artery Aneurysm in a Case of Moyamoya Disease: A Rare Entity.","authors":"Krushikumar B Soladhra, Arvindkumar Verma, Varshesh K Shah, Dharmikkumar K Velani, Jaimin Modh","doi":"10.1055/s-0044-1790518","DOIUrl":"10.1055/s-0044-1790518","url":null,"abstract":"<p><p>Moyamoya disease is a rare condition characterized by progressive narrowing and occlusion of internal carotid artery and other major arteries of the brain with formation of multiple collaterals. The incidence of aneurysm in moyamoya disease is higher than normal population. Treating the simultaneous pathology of aneurysm and moyamoya disease in an individual is a rare entity. A 35-year-old male presented with headache, loss of consciousness, and generalized tonic-clonic seizure with subarachnoid hemorrhage. Digital Subtraction angiography showed moyamoya disease with left superior cerebellar artery aneurysm. Rupture of aneurysm was suspected to be the source of subarachnoid hemorrhage. Patient underwent clipping of the left superior cerebellar artery aneurysm with encephalo-duro-arterio-myo-synangiosis. Patient survived the procedures. All patients with subarachnoid hemorrhage in moyamoya disease should undergo angiogram and aneurysm should be looked for carefully. The site of aneurysm and the risk for damaging the collaterals should be kept in mind while planning the surgery in such cases.</p>","PeriodicalId":94300,"journal":{"name":"Asian journal of neurosurgery","volume":"19 4","pages":"808-811"},"PeriodicalIF":0.0,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11588598/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142741950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multiple Shunt Catheter Tips Migration into an Inguinal Hernia in an Adult. 成人腹股沟疝中的多个分流导管尖端移位。
Asian journal of neurosurgery Pub Date : 2024-09-10 eCollection Date: 2024-12-01 DOI: 10.1055/s-0044-1790291
Zuhdy Alsheik, Emil Margolin, Sharif Robin, Daniel Dykman, Haim Ezer
{"title":"Multiple Shunt Catheter Tips Migration into an Inguinal Hernia in an Adult.","authors":"Zuhdy Alsheik, Emil Margolin, Sharif Robin, Daniel Dykman, Haim Ezer","doi":"10.1055/s-0044-1790291","DOIUrl":"10.1055/s-0044-1790291","url":null,"abstract":"<p><p>Although ventriculoperitoneal shunt tip migration into an inguinal hernia is considered common in children, while in adults it is quite rare. In fact, only a handful of cases have been reported in the literature. We report a rare case whereby two catheter tips (one from a lateral ventricle shunt and a second from a 4th ventricular shunt) migrated into an inguinal hernia. This migration caused distal shunt malfunction, and only distal catheter shortening and suturing to the abdominal wall caused the two shunts to function again.</p>","PeriodicalId":94300,"journal":{"name":"Asian journal of neurosurgery","volume":"19 4","pages":"805-807"},"PeriodicalIF":0.0,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11588593/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142741100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of Effectiveness of Brivaracetam and Levetiracetam for Prophylaxis of Early Post-Traumatic Seizures: A Prospective Comparative Interventional Study. 比较 Brivaracetam 和 Levetiracetam 对创伤后早期癫痫发作的预防效果:前瞻性比较干预研究》。
Asian journal of neurosurgery Pub Date : 2024-09-10 eCollection Date: 2024-12-01 DOI: 10.1055/s-0044-1790516
Rajan Pandya, Ponraj Kamatchi Sundaram, Shashank Singh Baghel
{"title":"Comparison of Effectiveness of Brivaracetam and Levetiracetam for Prophylaxis of Early Post-Traumatic Seizures: A Prospective Comparative Interventional Study.","authors":"Rajan Pandya, Ponraj Kamatchi Sundaram, Shashank Singh Baghel","doi":"10.1055/s-0044-1790516","DOIUrl":"10.1055/s-0044-1790516","url":null,"abstract":"<p><p><b>Introduction</b>  Early posttraumatic seizures (EPTS) are a major complication after a head injury, defined as seizures developing within the first 7 days of trauma. Levetiracetam has become a popular drug for the prevention of posttraumatic seizures in institutions worldwide. However, it has been reportedly associated with adverse effects like behavioral changes and somnolence. This study aimed to compare the efficacy of a newer drug, brivaracetam, which is reported to have a better pharmacokinetic profile. These findings may be significant in providing a safer yet efficacious alternative to levetiracetam. <b>Objective</b>  The aim of this study was to evaluate the efficacy of brivaracetam for prophylaxis of EPTS and to compare it with levetiracetam. <b>Materials and Methods</b>  A prospective, single-blind, parallel-group (alternate allocation) controlled trial over 100 patients admitted with traumatic brain injury in the Department of Neurosurgery, Goa Medical College, Panaji, Goa, India. The data was analyzed using IBM SPSS Statistics 29.0. <b>Results</b>  Twenty patients developed EPTS in the study group: 8 from the group receiving brivaracetam and 12 from the group receiving levetiracetam. Although the brivaracetam group had a lower incidence of EPTS, the difference was not statistically significant. Eleven patients from the levetiracetam group developed side effects, while six patients from the brivaracetam group had side effects. There was no significant difference in the incidence of side effects. <b>Conclusion</b>  Brivaracetam has efficacy equal to that of levetiracetam for prophylaxis of EPTS.</p>","PeriodicalId":94300,"journal":{"name":"Asian journal of neurosurgery","volume":"19 4","pages":"728-734"},"PeriodicalIF":0.0,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11588607/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142741953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hematologic Indices and Chronic Subdural Hematoma: A Single-Center Cohort Study. 血液指标与慢性硬膜下血肿:单中心队列研究
Asian journal of neurosurgery Pub Date : 2024-09-10 eCollection Date: 2024-12-01 DOI: 10.1055/s-0044-1790237
Hrvoje Barić, Sara Komljenović, Katarina Bilić, William Migo, Julius Mautin Vitowanu, Andrej Desnica, Goran Mrak
{"title":"Hematologic Indices and Chronic Subdural Hematoma: A Single-Center Cohort Study.","authors":"Hrvoje Barić, Sara Komljenović, Katarina Bilić, William Migo, Julius Mautin Vitowanu, Andrej Desnica, Goran Mrak","doi":"10.1055/s-0044-1790237","DOIUrl":"10.1055/s-0044-1790237","url":null,"abstract":"<p><p><b>Objective</b>  Chronic subdural hematoma (cSDH) is common, predominantly affects the elderly, often recurs after treatment, and can have serious complications, including death. Inflammation plays an important role in cSDH and it has been previously shown that some laboratory indices are useful as prognostic markers. The aim was to research the role of hematologic and inflammatory markers in cSDH. <b>Materials and Methods</b>  A single-center archival database review to retrieve data on cSDH cases operated on between 2018 and 2020, including: (1) sociodemography (age, gender), (2) clinics (Glasgow Coma Score [GCS], anticoagulants, chronic conditions), (3) laboratory (leukocyte, neutrophil, platelet, C-reactive protein, hemoglobin, red cell distribution width [RDW], neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio [PLR], systemic immune-inflammatory index [SII]), (4) cSDH (size, location, midline shift), and (5) treatment (craniotomy/craniostomy, drainage). Primary outcome was Glasgow Outcome Score (GOS) at discharge and at 1 year, and secondary outcomes were 1 year mortality, resurgery, and recurrence. Hematological and inflammatory indices were compared across two cSDH thickness groups. <b>Results</b>  Seventy-two patients were included, 25 women and 47 men, median age 77 years. Seventeen (23.6%) patients had chronic anticoagulant treatment. The majority had a chronic comorbidity: 19 (26.4%) diabetes, 48 (66.7%) hypertension, and 56 (77.8%) other chronic diseases. Median preoperative GCS was 15. Median cSDH thickness was 22.9 mm, sidedness was equally distributed, and midline shift occurred in 60 (83.3 %) patients, with median midline shift of 8.4 mm. The majority of patients underwent a single craniostomy ( <i>n</i>  = 44, 61.1%), and in all patients a subdural drainage was placed. Median GOS at discharge and at 1 year postoperatively was 5. Mortality was 11.1%, and 16.7% of patients were lost to follow-up. Within the 1-year follow-up, 27.8% of patients had disease recurrence, 25% underwent a repeat surgery. In the \"above\" versus \"below\" 15 mm cSDH thickness group there were significant differences in P count (211.5 vs. 279.5 × 10 <sup>9</sup> /L, <i>p</i>  = 0.009), RDW (13.3 vs. 12.6, <i>p</i>  = 0.031), SII (1782 vs. 2653, <i>p</i>  = 0.025), and PLR (26.2 vs. 36.7, <i>p</i>  = 0.042). <b>Conclusion</b>  Hematological indices bear a diagnostic and prognostic potential in cSDH management.</p>","PeriodicalId":94300,"journal":{"name":"Asian journal of neurosurgery","volume":"19 4","pages":"735-740"},"PeriodicalIF":0.0,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11588605/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142741999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信