{"title":"Adverse side effects, including agranulocytosis and anemia, from methimazole treatment of a hyperthyroid cat.","authors":"Cristian Mastrangelo","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A 13-year-old spayed female domestic shorthair cat was brought to a veterinary clinic because of lethargy and anorexia. The cat had a history of hyperthyroidism and had been treated with methimazole for 40 d before the appointment. Hematologic examination revealed a severe non-regenerative anemia and leukopenia characterized by severe neutropenia along with low basophil and eosinophil numbers. Discontinuation of methimazole resulted in the complete return to normal values of the white blood cell numbers and a marked increase in red blood cell numbers. This case demonstrated the need for follow-up veterinary examinations after prescription of methimazole treatment.</p>","PeriodicalId":9429,"journal":{"name":"Canadian Veterinary Journal-revue Veterinaire Canadienne","volume":"66 2","pages":"206-209"},"PeriodicalIF":0.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11770607/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143078338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ulrika Maire, Martin Genton, Amelie Vitte-Rossignol
{"title":"Iatrogenic cecal perforation after abdominal drain placement on a horse.","authors":"Ulrika Maire, Martin Genton, Amelie Vitte-Rossignol","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A 16-year-old, French saddlebred horse was referred for examination because of colic signs, diagnosed with incarceration of the jejunum in a mesoduodenic rent, and subsequently treated surgically (with an end-to-end anastomosis of the jejunum and an enterotomy of the pelvic flexure). The horse initially recovered without complications; however, on the following day, it exhibited moderate signs of endotoxemia and severe serosanguineous discharge from the abdominal wound. Abdominal ultrasonography revealed substantial peritoneal effusion, necessitating the placement of an abdominal drain. The blind drain insertion resulted in the drainage of a brown, malodorous liquid, identified as enteral fluid. Subsequently, the drain inadvertently penetrated the viscera, prompting immediate surgery. An embolectomy catheter was placed in the drain before induction, and the Fogarty catheter cuff was inflated as the horse was induced. The drain was carefully removed from the viscera, maintaining traction on the embolectomy catheter until a repeat laparotomy was done. Moderate contamination of the abdominal cavity occurred during the iatrogenic perforation of the cecum. The balloon catheter effectively sealed the breach in the cecum, demonstrating sufficient strength to pull on the viscera without causing tears. The abdominal cavity was lavaged with 80 L of Ringer's lactate, and another abdominal drain was placed. The horse recovered without further complications throughout the remainder of its hospitalization and returned to its intended use within 6 mo. Key clinical message: Abdominal drain placement carries the risk of complications, including enteric misplacement. Temporary occlusion of the defect is achievable using an embolectomy catheter pending surgery. Swift action in response to complications can help limit contamination of the abdominal cavity.</p>","PeriodicalId":9429,"journal":{"name":"Canadian Veterinary Journal-revue Veterinaire Canadienne","volume":"66 2","pages":"138-142"},"PeriodicalIF":0.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11770612/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143078536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Melania Dallago, Clarissa Dallago, Bruno Peirone, Alessandro Boero Baroncelli, Tommaso Nicetto, Piero Costa, Evelien De Bakker
{"title":"Assessment of 3 detorsional planning techniques for distal femoral osteotomy to the distal femoral metaphysis in 3 dog breeds.","authors":"Melania Dallago, Clarissa Dallago, Bruno Peirone, Alessandro Boero Baroncelli, Tommaso Nicetto, Piero Costa, Evelien De Bakker","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the shape of the distal femoral metaphysis in various dog breeds and apply femoral detorsional techniques.</p><p><strong>Animals and procedure: </strong>Computed tomographic scans of 6 right femurs of dogs from 3 breeds, Chihuahua, border collie, and rottweiler, designated Groups 1, 2, and 3, respectively. On the distal femoral metaphysis axial image, just proximal to the femoral trochlea, femoral craniocaudal and mediolateral diameters were measured and their ratio (R) was calculated. The circumference technique (CiT), cortical arch length method (CAL), and geometric method (GM) were applied to these images to simulate 15° of detorsion. For each technique, the detorsion amount and the resulting detorsion angle (α) were calculated and reported.</p><p><strong>Results: </strong>Means and standard deviations of R were 0.59 ± 0.10, 0.81 ± 0.05, and 0.87 ± 0.08 for Groups 1, 2, and 3, respectively. In Group 1, due to the femoral flattened shape, the techniques were not reliable. In Groups 2 and 3, the correction was acceptable.</p><p><strong>Conclusion and clinical relevance: </strong>The distal femoral metaphyseal axial section shape in Group 1 was comparable to an ellipse. Therefore, the tested techniques were not reliable in chondrodystrophic dogs.</p>","PeriodicalId":9429,"journal":{"name":"Canadian Veterinary Journal-revue Veterinaire Canadienne","volume":"66 2","pages":"151-158"},"PeriodicalIF":0.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11770625/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143078523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The brave new world of clinical veterinary genetics.","authors":"David W Silversides","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The creation of purebred breeds of domestic animals has been accompanied by inbreeding and an increased incidence of simple genetic diseases within these breeds and animals. The veterinary profession has largely been a spectator of recent developments in companion animal genetics. A review of the current state of veterinary genetics for the small animal practitioner is provided that includes an overview of commercial DNA service providers as well as a review of information sources useful for clinical veterinary genetics.</p>","PeriodicalId":9429,"journal":{"name":"Canadian Veterinary Journal-revue Veterinaire Canadienne","volume":"66 2","pages":"210-212"},"PeriodicalIF":0.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11770617/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143078609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Preparation, articulation, and photogrammetry of a neonatal moose <i>(Alces alces)</i> skeleton.","authors":"Holly McVea, Lena Richter, Rod McLatchy, Roy Rea","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>Neonatal skeletal articulations for research and display purposes are uncommon due to issues surrounding incomplete bone maturation and reduced structural integrity that affect the bone preparation and articulation procedures. The present project was designed to add to the veterinary literature on neonatal moose <i>(Alces alces)</i> osteological specimens, document the procedures of preparing and articulating a delicate specimen, and construct a 3-dimensional (3D) scan of the articulated skeleton that could be used for scientific and veterinary research and study worldwide.</p><p><strong>Animal: </strong>A neonatal moose that had succumbed to capture myopathy resulting from entanglement in a barbed wire fence was the sole subject of this project.</p><p><strong>Procedure: </strong>The neonatal moose carcass was degloved, the bones processed and cleaned, the skeleton articulated, and the articulated skeleton rendered into a 3D model using photogrammetry.</p><p><strong>Results: </strong>The result was an articulated neonatal moose skeleton. The articulation is on display at the University of Northern British Columbia (UNBC); the 3D model is available on UNBC's website.</p><p><strong>Conclusion and clinical relevance: </strong>This project adds to the literature and makes available tools to study neonatal ungulate <i>(A. alces)</i> allometry, morphometry, osteology, and skeletal articulation. The documented processes and 3D model can be used as references in veterinary and biological research, study, and instruction. In addition, the 3D model is available to download (open source) for future projects from UNBC (www.unbc.ca/roy-rea/moose-calf-articulation).</p>","PeriodicalId":9429,"journal":{"name":"Canadian Veterinary Journal-revue Veterinaire Canadienne","volume":"66 1","pages":"15-19"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11705174/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142945081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Georgia Kritikos, Gabrielle Monteith, J Scott Weese, Shane W Bateman
{"title":"Prevalence of enteropathogens and endoparasites in cats at an animal shelter in Ontario.","authors":"Georgia Kritikos, Gabrielle Monteith, J Scott Weese, Shane W Bateman","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>To determine the prevalence of fecal microorganisms and parasites in a population of sheltered cats, and to identify specific animal factors associated with infection.</p><p><strong>Animals: </strong>A total of 79 sheltered cats and kittens in Guelph, Ontario.</p><p><strong>Procedure: </strong>A fecal sample was collected from each animal upon shelter entry. A second sample was collected following deworming treatment. Microorganism and parasite prevalence was assessed by PCR assays. A linear mixed model was used to determine the relationships between animal factors (intake source, age, sex, body condition score, time between deworming and sample collection, and fecal consistency) and fecal microorganisms and parasites, as well as to compare samples taken before and after deworming.</p><p><strong>Results: </strong><i>Clostridium perfringens</i> alpha toxin gene and feline coronavirus (FCoV) DNA were the most common abnormalities identified. <i>Giardia</i> spp., <i>C. perfringens</i> enterotoxin, and <i>Campylobacter jejuni</i> were rare. <i>Clostridium perfringens</i> prevalence was negatively associated with increasing age (<i>P</i> = 0.04) and FCoV prevalence was positively associated with softer stool (<i>P</i> = 0.02). Hookworms, roundworms, and tapeworms were uncommon, and prevalence was not affected by any animal factor. Parasite prevalence decreased after deworming (<i>P</i> = 0.04).</p><p><strong>Conclusion and clinical relevance: </strong>There do not appear to be durable relationships between <i>C. perfringens</i> and FCoV prevalence and animal factors in cats. A larger population of cats is required to identify potential relationships between microorganism and parasite prevalence and animal-specific demographic factors.</p>","PeriodicalId":9429,"journal":{"name":"Canadian Veterinary Journal-revue Veterinaire Canadienne","volume":"66 1","pages":"70-78"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11705169/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142945082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical and magnetic resonance imaging findings of presumed limber tail syndrome in a cat.","authors":"Marie Avril, Anne-Sophie Bedu, Thibaut Troupel","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A 4-year-old neutered female domestic shorthair indoor cat was presented with sudden onset of abnormal and painful tail-carriage. The tail was held horizontally for the first centimeters from the base and a flaccid paralysis was evident more distally. Magnetic resonance imaging of the lumbosacral spine and tail revealed a lesion located in the right <i>sacrocaudalis dorsalis lateralis</i> and <i>medialis</i> muscles along the 1st coccygeal vertebrae. The lesion was poorly defined, T2-weighted hyperintense, and T1-weighted isointense compared to surrounding and contralateral muscles and had a strong homogeneous contrast enhancement. The cat began receiving prednisolone and clinical signs progressively improved and disappeared within 2 wk. Clinical presentation and MRI findings were comparable to those previously described in dogs with limber tail syndrome. To the best of our knowledge, limber tail syndrome has not been reported in cats. However, based on this case, we inferred that limber tail syndrome may occur in cats. Key clinical message: Limber tail syndrome could be considered among the differential diagnoses in both dogs and cats presented with acute and flaccid tail paralysis. Limber tail syndrome is essentially a clinical diagnosis. An animal with suspected limber tail syndrome should initially be treated conservatively and, if no improvement or further deterioration are observed, MRI could be considered to refine the diagnosis, as it allows identification of tail muscles and can detect lesions affecting these structures.</p>","PeriodicalId":9429,"journal":{"name":"Canadian Veterinary Journal-revue Veterinaire Canadienne","volume":"66 1","pages":"40-45"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11705180/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142944962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Around the world in 80 days - Part 3.","authors":"Tim Arthur","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":9429,"journal":{"name":"Canadian Veterinary Journal-revue Veterinaire Canadienne","volume":"66 1","pages":"6-9"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11705178/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142945035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Siheng Xie, Bernard Seguin, Lisa Brownlee, Manuel Boller
{"title":"Hepatic <i>Mycobacterium heckeshornense</i> infection in a dog with cavitary lung disease.","authors":"Siheng Xie, Bernard Seguin, Lisa Brownlee, Manuel Boller","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A 9-year-old neutered male cairn terrier dog was initially presented because of inappetence, increased respiratory effort, and occasional coughing. A cavitary lung mass was diagnosed using CT and removed with lung lobectomy. Histopathology of the mass revealed necrosuppurative inflammation with acid-fast rod bacteria in macrophages, with <i>Mycobacterium</i> spp. a possible cause. Routine bacterial culture of a lung-lesion swab was negative for growth. The dog improved and did not show any clinical signs for 9 mo after the surgery, at which time a second recheck CT scan and bloodwork revealed diffuse hepatopathy and peritoneal effusion. The dog was hospitalized 3 d after this recheck because of signs of acute abdomen with vomiting, melena, polyuria, and polydipsia. Cytology of liver fine-needle aspirates revealed marked pyogranulomatous inflammation with acid-fast rod bacteria in histiocytes; phylogenetic analysis of hsp65 PCR amplicons from that tissue identified sequences identical to <i>Mycobacterium heckeshornense.</i> No other bacteria were isolated on a routine bacterial culture of a liver swab. Hepatic mycobacteriosis was treated with long-term enrofloxacin, clarithromycin, and doxycycline. The dog improved slowly, and the liver enzymes returned to normal after 4 mo of treatment. This is the first reported case of <i>M. heckeshornense</i> infection in a dog. Diseases caused by non-tuberculous mycobacteria such as <i>M. heckeshornense</i> are generally not reportable due to low risk of transmission between and to humans, but the zoonotic potential warrants further research in the future. Key clinical message: Dogs without overt immunodeficiency can be at risk of <i>M. heckeshornense</i> infection and can develop life-threatening pathology affecting multiple organs. However, clinical resolution can be achieved even in a severely affected dog. If <i>Mycobacterium</i> is suspected, it is important to consult with diagnostic laboratories to ensure correct samples are obtained and correct analytical procedures are used.</p>","PeriodicalId":9429,"journal":{"name":"Canadian Veterinary Journal-revue Veterinaire Canadienne","volume":"66 1","pages":"28-34"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11705168/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142945078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}