Canadian Veterinary Journal-revue Veterinaire Canadienne最新文献

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Combination chemotherapy of imatinib, vinblastine, and prednisolone in a dog with cutaneous mast cell tumor: Evaluation of treatment response with 18F-fluorodeoxyglucose positron emission tomography. 伊马替尼、长春碱和强的松龙联合化疗犬皮肤肥大细胞瘤:用18f -氟脱氧葡萄糖正电子发射断层扫描评价治疗反应
IF 0.9 4区 农林科学
Sejung Ahn, Yeon Chae, Taesik Yun, Hakhyun Kim, Byeong-Teck Kang
{"title":"Combination chemotherapy of imatinib, vinblastine, and prednisolone in a dog with cutaneous mast cell tumor: Evaluation of treatment response with <sup>18</sup>F-fluorodeoxyglucose positron emission tomography.","authors":"Sejung Ahn, Yeon Chae, Taesik Yun, Hakhyun Kim, Byeong-Teck Kang","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>An 8-year-old neutered male Maltese dog was presented with 6 palpable cutaneous masses on the neck and thorax 1 y after the surgical excision of mast cell tumors (MCT) from the mid-thoracic and right axillary regions. Before chemotherapy, the sum of the masses' diameters was 19.0 cm. <sup>18</sup>F-fluorodeoxyglucose (FDG)-positron emission tomography/computed tomography (PET/CT) revealed hypermetabolic lesions within the skin overlying the ventral thorax, bilateral prescapular lymph nodes, and right axillary lymph node. The dog was diagnosed with MCT recurrence and treated with combination chemotherapy comprising imatinib, vinblastine, and prednisolone. After completion of 2 16-week chemotherapy regimens, the sum of the masses' diameters decreased to 3.6 cm. For assessment of the chemotherapy response and guidance for subsequent therapeutic plans, follow-up FDG-PET/CT was undertaken 25 d after completion of the 2nd chemotherapy regimen. It demonstrated a reduction in FDG uptake in all areas compared with that on the initial scan, except for the middle thoracic mass. After follow-up FDG-PET/CT, a 3rd chemotherapy regimen was implemented, and the dog died 416 d after the initiation of chemotherapy. There are no reports of a combination chemotherapy with imatinib, vinblastine, and prednisolone for treating canine cutaneous MCT. This case highlighted the potential therapeutic use of this combination chemotherapy for recurrent canine MCTs. Furthermore, this report indicates that FDG-PET/CT may be useful for assessing malignancy, evaluating chemotherapy responses, and establishing treatment plans for canine cutaneous MCTs. Key clinical message: Combination chemotherapy of imatinib, vinblastine, and prednisolone is a potential therapeutic regimen for recurrent cutaneous MCTs in dogs. In addition, FDG-PET/CT may be a potentially useful tool for assessing malignancy, evaluating chemotherapy responses, and guiding further therapeutic decisions.</p>","PeriodicalId":9429,"journal":{"name":"Canadian Veterinary Journal-revue Veterinaire Canadienne","volume":"66 7","pages":"755-763"},"PeriodicalIF":0.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12261935/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144648666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Government Relations 101. 政府关系101。
IF 0.9 4区 农林科学
Tim Arthur
{"title":"Government Relations 101.","authors":"Tim Arthur","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":9429,"journal":{"name":"Canadian Veterinary Journal-revue Veterinaire Canadienne","volume":"66 7","pages":"705-707"},"PeriodicalIF":0.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12261930/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144648626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Suspected Grey Turner's sign in a dog with acute pancreatitis. 一只狗患有急性胰腺炎,疑似格雷·特纳症状。
IF 0.9 4区 农林科学
Lucy Yuan, Fernanda Camacho, Mark Dunning
{"title":"Suspected Grey Turner's sign in a dog with acute pancreatitis.","authors":"Lucy Yuan, Fernanda Camacho, Mark Dunning","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>An 11-year-old fox terrier was presented with bicavitary effusions following a 2-day history of vomiting and panting. After referral for management of the effusions, following radiographic and ultrasonographic imaging, the dog was diagnosed with acute necrotizing pancreatitis. On Day 5 of hospitalization, the dog developed bilateral abdominal-wall ecchymosis, prompting concerns that this was an example of Grey Turner's sign (GTS), described in human medicine as a subcutaneous manifestation of intra-abdominal hemorrhage presenting as ecchymosis of the flanks and commonly associated with severe acute necrotizing pancreatitis. This is apparently the first time that suspected GTS has been described in a dog with acute necrotizing pancreatitis. Recognizing GTS in dogs may alert clinicians to serious intra-abdominal pathology and prompt immediate further investigations. Key clinical message: We describe a case of suspected GTS (bilateral flank ecchymoses) in a dog, apparently for the first time. Grey Turner's sign may occur in cases of intra-abdominal hemorrhage as well as intra-abdominal inflammation in which hemoabdomen is not present. Recognizing GTS in dogs may alert clinicians to serious intra-abdominal disease and prompt immediate further investigations.</p>","PeriodicalId":9429,"journal":{"name":"Canadian Veterinary Journal-revue Veterinaire Canadienne","volume":"66 7","pages":"723-727"},"PeriodicalIF":0.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12261929/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144648632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
New-onset atrial fibrillation and flutter in a mechanically ventilated dog with bronchopneumonia. 机械通气犬伴支气管肺炎的新发心房颤动和扑动。
IF 0.9 4区 农林科学
Amédée André, Jo-Annie Letendre, Bérénice Conversy, Christina Plante, Elyzabeth Lemieux
{"title":"New-onset atrial fibrillation and flutter in a mechanically ventilated dog with bronchopneumonia.","authors":"Amédée André, Jo-Annie Letendre, Bérénice Conversy, Christina Plante, Elyzabeth Lemieux","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A 3-year-old intact male English bulldog was presented to a veterinary teaching hospital because of respiratory distress secondary to bronchopneumonia and brachycephalic obstructive airway syndrome. Due to severe hypoxemia, the dog was mechanically ventilated. He developed atrial flutter and atrial fibrillation during hospitalization. The arrhythmias were suspected to be secondary to the systemic inflammation, severe brachycephalic obstructive airway syndrome, and high vagal tone without underlying cardiac pathology identified by echocardiography. Considering the hemodynamic instability of the dog, cardioversion was attempted. The arrhythmias were refractory to conventional treatments, discontinuation of pro-arrhythmic medications, and trials of Class I and II antiarrhythmics. Cardioversion occurred 2 h following oral sotalol administration after the dog received a diltiazem infusion for 30 h, and the dog recovered successfully. After the dog was discharged and prescribed sotalol that was subsequently discontinued, he did not experience any recurrence of arrhythmias during follow-up examinations. Key clinical message: To the authors' knowledge, this is the first report of a medical cardioversion of atrial flutter and atrial fibrillation in a mechanically ventilated dog with bronchopneumonia. Clinicians should be aware of the risk of acute cardiac events in dogs with systemic inflammation, such as bronchopneumonia, especially in brachycephalic breeds with high vagal tone.</p>","PeriodicalId":9429,"journal":{"name":"Canadian Veterinary Journal-revue Veterinaire Canadienne","volume":"66 7","pages":"740-746"},"PeriodicalIF":0.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12261944/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144648631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sarcocystis-associated myocarditis in a domestic cat. 家猫肌囊炎相关心肌炎。
IF 0.9 4区 农林科学
Abedin Shaban Zadeh, Elisabeth Snead, Enrique Aburto, Savannah Goldstein
{"title":"<i>Sarcocystis</i>-associated myocarditis in a domestic cat.","authors":"Abedin Shaban Zadeh, Elisabeth Snead, Enrique Aburto, Savannah Goldstein","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This report describes a 2-year-old spayed female domestic shorthair cat presented because of severe, acute respiratory distress and ultimately diagnosed with myocarditis and secondary congestive heart failure associated with <i>Sarcocystis</i> spp. Despite therapy with oxygen, furosemide, and butorphanol, the cat deteriorated rapidly, became moribund, and was euthanized. Lymphohistiocytic myocarditis associated with protozoal organisms with evidence of secondary congestive heart failure was diagnosed based on gross and histological findings. Protozoal cysts were identified within the myocardium and <i>Sarcocystis</i>-containing cysts were also seen in lingual and periocular striated muscles with associated myositis. Immunohistochemical analysis confirmed that the protozoal organisms were <i>Sarcocystis</i> spp. Molecular identification using polymerase chain reaction identified the etiologic agent as <i>S. arctica/caninum</i>. Although <i>Sarcocystis</i> infection has been documented in striated muscles of cats worldwide, this is typically an incidental finding. If disease occurs, it usually leads to neurologic signs from a <i>Sarcocystis</i>-induced encephalomyelitis. To the best of our knowledge, this is the first report of <i>Sarcocystis</i> spp. affecting the cardiac muscle of a domestic cat with a fatal outcome. Key clinical message: <i>Sarcocystis</i> spp. is a novel cause of heart failure in cats due to lymphohistiocytic myocarditis.</p>","PeriodicalId":9429,"journal":{"name":"Canadian Veterinary Journal-revue Veterinaire Canadienne","volume":"66 7","pages":"715-722"},"PeriodicalIF":0.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12261931/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144648664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Human infections with the raccoon roundworm, Baylisascaris procyonis: A scoping review. 浣熊蛔虫,原yonis Baylisascaris的人类感染:范围综述。
IF 0.9 4区 农林科学
J Scott Weese, Jason W Stull
{"title":"Human infections with the raccoon roundworm, <i>Baylisascaris procyonis:</i> A scoping review.","authors":"J Scott Weese, Jason W Stull","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>The raccoon roundworm, <i>Baylisascaris procyonis</i>, is a gastrointestinal parasite with zoonotic implications.</p><p><strong>Objective: </strong>To identify and describe available evidence pertaining to clinical <i>B. procyonis</i> infections in humans.</p><p><strong>Procedure: </strong>A scoping review of the MEDLINE (<i>via</i> OVID), Web of Science, and CAB Abstracts databases.</p><p><strong>Results: </strong>Sixty infections were identified. Most (38, 75%) were in males and the median age was 2.9 y (range: 9 mo to 73 y). Forty-seven (78%) individuals had neurological disease (9 with concurrent ocular disease), 11 had ocular disease alone, 1 had eosinophilic cardiac pseudotumor, and 1 was an incidental autopsy finding. Clinical signs of neurological disease were highly variable and progressive, with vague initial signs and symptoms. Ocular disease was most often manifested as diffuse unilateral subacute neuroretinitis, retinal lesions, and painless loss of vision and visual acuity. Outcomes were reported for 42 individuals with neurological disease: 8 (19%) died, 4 (10%) fully recovered, and the remaining 30 (71%) had mild to significant neurological residual deficits. Most (7/10, 70%) individuals with solely ocular disease had permanent vision loss.</p><p><strong>Conclusion and clinical relevance: </strong>The severity of the disease, poor response to treatment, and widespread presence of the parasite in areas where raccoons are endemic indicate a need for awareness among the public, healthcare providers, and veterinarians.</p>","PeriodicalId":9429,"journal":{"name":"Canadian Veterinary Journal-revue Veterinaire Canadienne","volume":"66 7","pages":"789-800"},"PeriodicalIF":0.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12261942/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144648628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnostic Ophthalmology. 诊断眼科。
IF 0.9 4区 农林科学
Marina L Leis, Lynne S Sandmeyer
{"title":"Diagnostic Ophthalmology.","authors":"Marina L Leis, Lynne S Sandmeyer","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":9429,"journal":{"name":"Canadian Veterinary Journal-revue Veterinaire Canadienne","volume":"66 7","pages":"803-805"},"PeriodicalIF":0.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12261936/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144648624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Veterinary Medical Ethics. 兽医医学伦理学。
IF 0.9 4区 农林科学
{"title":"Veterinary Medical Ethics.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":9429,"journal":{"name":"Canadian Veterinary Journal-revue Veterinaire Canadienne","volume":"66 7","pages":"710-712"},"PeriodicalIF":0.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12261934/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144648634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of salivary urea nitrogen test in cats with lower urinary tract outflow obstructions. 下尿路流出梗阻猫唾液尿素氮试验的评价。
IF 0.9 4区 农林科学
Deborah Yee, Amber Carson, Laurel Thiessen, Sydni Stroebel, Lisa Thompson, Joseph Cyrus Parambeth
{"title":"Evaluation of salivary urea nitrogen test in cats with lower urinary tract outflow obstructions.","authors":"Deborah Yee, Amber Carson, Laurel Thiessen, Sydni Stroebel, Lisa Thompson, Joseph Cyrus Parambeth","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>To determine if the Kidney-Chek salivary test (SN Biomedical) could accurately detect azotemia in cats with urethral obstruction.</p><p><strong>Animals: </strong>Cats included in the study were adult male cats > 1 y of age, each with an inexpressible bladder > 4 cm in diameter as visualized on ultrasound examination.</p><p><strong>Procedure: </strong>Twenty-one cats meeting these criteria were admitted to a veterinary hospital. Each cat had salivary urea nitrogen (SUN) assessed with a Kidney-Chek test, following the Kidney-Chek protocol. Blood urea nitrogen (BUN) and creatinine were also assessed.</p><p><strong>Results: </strong>Twenty-one cats were included in the study. One cat was excluded due to dry saliva sample collection. Final results showed that the SUN test strips were 84% accurate in identifying azotemia or non-azotemia. Azotemia was correctly identified in 78.57% of cats and non-azotemia was correctly identified in 90.9% of cats. Positive correlations were noted between SUN and BUN and SUN and creatinine. There was a negative correlation between SUN and urine specific gravity. No correlation was identified between hydration level and SUN. Hydration had no effect on test results.</p><p><strong>Conclusion: </strong>Salivary urea nitrogen results from the Kidney-Chek salivary test were correlated to BUN and creatinine results. This test can be used to detect azotemia in selected cases of feline urethral obstruction.</p><p><strong>Clinical relevance: </strong>This study demonstrated that SUN may be used to detect azotemia in cats at risk of urinary tract obstruction. This test may be useful for clients to use at home, before bringing their animals to the clinic, or as a cost-saving alternative in a clinic setting. Access to an immediately available azotemia reading can help practitioners make guided treatment recommendations and determine if cats are good candidates for outpatient treatment.</p>","PeriodicalId":9429,"journal":{"name":"Canadian Veterinary Journal-revue Veterinaire Canadienne","volume":"66 7","pages":"774-780"},"PeriodicalIF":0.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12261947/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144648625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Addressing animal abuse and neglect in the veterinary profession. 解决兽医职业中虐待和忽视动物的问题。
IF 0.9 4区 农林科学
Ashley L Powell, Cecily Grant, Carleigh Cathcart, Heather Chandler, Elizabeth Hodges, Alexandre Jalbert, Marilyn Keaney
{"title":"Addressing animal abuse and neglect in the veterinary profession.","authors":"Ashley L Powell, Cecily Grant, Carleigh Cathcart, Heather Chandler, Elizabeth Hodges, Alexandre Jalbert, Marilyn Keaney","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":9429,"journal":{"name":"Canadian Veterinary Journal-revue Veterinaire Canadienne","volume":"66 7","pages":"806-813"},"PeriodicalIF":0.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12261941/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144648665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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