Canadian Veterinary Journal-revue Veterinaire Canadienne最新文献

{"title":"Right and left heart morphology and function in dogs with compensated chronic right ventricular pressure overload secondary to pulmonic stenosis or precapillary pulmonary hypertension.","authors":"Emilie Van Renterghem, Marine Lekane, Kris Gommeren, Anne-Christine Merveille","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>The study objective was to compare right and left heart morphology and function in dogs with compensated chronic right ventricular (RV) pressure overload secondary to pulmonic stenosis (PS) and chronic precapillary pulmonary hypertension (cPCPH).</p><p><strong>Animals and procedure: </strong>This cross-sectional observational retrospective study included 64 client-owned dogs, including healthy controls (<i>n</i> = 15) and groups with PS (<i>n</i> = 31) and cPCPH (<i>n</i> = 18). The RV pressure gradient (RVPG) was determined by peak pulmonic or peak tricuspid regurgitation velocity and needed to be > 55 mmHg. Echocardiographic parameters assessing RV size [indexed diameter (RVIDd/Ao), area (N-RVAd) in diastole], hypertrophy [(RVFWd/LVFWd), (RVFWd/RVIDd)], and systolic function [fractional area change (RVFAC), indexed area in systole (N-RVAs)] were documented. Interventricular septal flattening was assessed using left ventricular (LV) eccentricity index (EI).</p><p><strong>Results: </strong>The RVPG was lower in cPCPH compared to PS [91 mmHg (55 to 158 mmHg) vs 108 mmHg (56 to 219 mmHg); <i>P</i> = 0.022]. The cPCPH group displayed more dilated [RVID/Ao: 0.13 (0.09 to 0.25) vs 0.10 (0.07 to 0.19), <i>P</i> = 0.004; N-RVAd: 1.17 (0.65 to 1.66) vs 0.83 (0.45 to 1.45), <i>P</i> = 0.010] and less hypertrophied RV [RVFWd/LVFWd: 0.9 (0.44 to 1.4) vs 1.0 (0.75 to 2.0), <i>P</i> < 0.020; RVFWd/RVIDd: 0.30 (0.19 to 0.55) vs 0.44 (0.24 to 0.67), <i>P</i> < 0.001], RV with poorer systolic function [N-RVAs: 0.69 (0.27 to 1.23) vs 0.35 (0.16 to 0.92), <i>P</i> = 0.001; RVFAC: 0.37 (0.14 to 0.66) vs 0.57 (0.29 to 0.71), <i>P</i> = 0.004], and more interventricular septal flattening [EIs:1.5 (1.09 to 5.71) vs 1.22 (0.88 to 2.1), <i>P</i> = 0.013] compared to PS. The RVID/Ao, N-RVAd, N-RVAs, RVFAC, RVFWd/RVIDd, and EIs were influenced by RVPG and the cause of RV pressure overload (independent of RVPG). Tricuspid regurgitation was more commonly observed in dogs with cPCPH.</p><p><strong>Conclusion and clinical relevance: </strong>After adjusting for RVPG, dogs with PS had less RV dilation, better RV function, and less left heart compromise compared to dogs with cPCPH.</p>","PeriodicalId":9429,"journal":{"name":"Canadian Veterinary Journal-revue Veterinaire Canadienne","volume":"67 5","pages":"535-545"},"PeriodicalIF":1.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13142056/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147834034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A retrospective case series of companion animals hospitalized for ethylene glycol poisoning at a Canadian veterinary teaching hospital.","authors":"Taylor Sauder, Madison Ricard, Jennifer Loewen, Vanessa Cowan","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Ethylene glycol (EG), the toxic ingredient in some antifreeze products, is a potent animal poison.</p><p><strong>Objective and animals: </strong>Our objective was to characterize EG poisoning in cats and dogs hospitalized at a Canadian veterinary teaching hospital.</p><p><strong>Procedure: </strong>We conducted a medical record review.</p><p><strong>Results: </strong>Twenty-one cases were included from the 17-year study period (dogs <i>n</i> = 15, cats <i>n</i> = 6). Common signalments were young male intact dogs (<i>n</i> = 5) and adult spayed female cats (<i>n</i> = 4). More cases were presented in summer (<i>n</i> = 10) than other seasons. Cases were often presented > 8 h after onset of signs (<i>n</i> = 12). Diagnostic tests included venous blood gas (<i>n</i> = 17), serum chemistry (<i>n</i> = 14), urinalysis (<i>n</i> = 14), AFAST/TFAST (<i>n</i> = 6), and full abdominal ultrasonography (<i>n</i> = 2). The most common treatments were IV fluids (<i>n</i> = 17) and 4-methylpyrazole (<i>n</i> = 8). The survival-to-discharge rates were 33% and 0% for dogs and cats, respectively.</p><p><strong>Conclusion: </strong>Poisoning with EG had a high fatality rate in dogs and cats presented to the emergency clinic. Animals were often presented late in the course of poisoning, making antidotal therapy unsuccessful.</p><p><strong>Clinical relevance: </strong>Regardless of time of year, EG should be considered a differential diagnosis for animals with CNS depression, gastrointestinal signs, and evidence of acute kidney injury. In clinics that do not have commercial diagnostic tests available, the authors recommend combining findings from venous blood gas, urinalysis, ultrasonography, and a Wood's lamp screen to establish a diagnosis.</p>","PeriodicalId":9429,"journal":{"name":"Canadian Veterinary Journal-revue Veterinaire Canadienne","volume":"67 5","pages":"553-562"},"PeriodicalIF":1.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13142060/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147833705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic Ophthalmology.","authors":"Lynne S Sandmeyer, Tammy J Owens","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":9429,"journal":{"name":"Canadian Veterinary Journal-revue Veterinaire Canadienne","volume":"67 5","pages":"591-596"},"PeriodicalIF":1.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13142053/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147833792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hypercalcemia as the primary finding in the first autochthonous <i>Angiostrongylus vasorum</i> (French heartworm) case in a dog from mainland Canada.","authors":"Christopher M Knap, Sheri Ross, Emilia Bourassi, Nina Germitsch","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>An 8-month-old intact male Labrador retriever dog from New Brunswick was referred to the Atlantic Veterinary College Small Animal Internal Medicine service (Prince Edward Island) for evaluation of marked hypercalcemia, polyuria-polydipsia, and urinary incontinence. Thoracic radiographs revealed a nonspecific, patchy-to-diffuse, interstitial-to-alveolar lung pattern, despite the absence of respiratory signs or abnormal lung auscultation. Fecal examination by Baermann analysis identified 1st-stage larvae of <i>Angiostrongylus vasorum</i>. Although <i>A. vasorum</i> has been documented in wild canid populations in parts of eastern Canada, this was the first confirmed case of an autochthonous infection in a companion animal in mainland Canada. The findings provide further evidence for the geographic expansion of <i>A. vasorum</i> within the Canadian Maritimes and contribute to a growing body of reports describing its emergence in North America. The dog's clinical presentation was atypical for angiostrongylosis, with no respiratory signs despite radiographic abnormalities, and hypercalcemia as a prominent clinical feature. These findings highlighted the variable and sometimes nonspecific nature of <i>A. vasorum</i> infection in dogs. Veterinarians practicing in eastern Canada should consider <i>A. vasorum</i> as a differential diagnosis in dogs with compatible clinical or imaging findings, even in the absence of respiratory signs or known endemicity. Routine Baermann fecal screening and prophylaxis with effective anthelmintics are recommended for dogs with increased risk of exposure to gastropod intermediate hosts. Key clinical message: <i>Angiostrongylus vasorum</i> is an emerging parasite in North America and can induce a variety of clinical signs in dogs. Veterinarians, specifically in the Canadian Maritimes, need to consider <i>A. vasorum</i> as a potential cause of respiratory signs, neurological signs, bleeding, and other clinical signs, and should recommend appropriate parasite prophylaxis in newly endemic areas.</p>","PeriodicalId":9429,"journal":{"name":"Canadian Veterinary Journal-revue Veterinaire Canadienne","volume":"67 5","pages":"504-510"},"PeriodicalIF":1.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13142070/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147833949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Medical management of ureteral stricture-induced hydronephrosis in a cat.","authors":"Xinyu Elvina Li","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A 3-year-old neutered male domestic shorthair cat was evaluated for hematuria. Ultrasonography and CT scanning identified moderate right-side hydronephrosis associated with right proximal and distal ureteral strictures, as well as partial stenosis of the left distal ureter. Medical management, including fluid therapy, ureteral muscle relaxants, and corticosteroids, was initiated but failed to improve progressive renal pelvic dilation as assessed on serial ultrasound scans. This case highlights the limited efficacy of conservative therapy and contributes to the growing body of evidence on the management of feline ureteral strictures.</p>","PeriodicalId":9429,"journal":{"name":"Canadian Veterinary Journal-revue Veterinaire Canadienne","volume":"67 5","pages":"572-576"},"PeriodicalIF":1.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13142066/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147834028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Veterinary Drug Labels and extra-label drug use: What's the issue?","authors":"Chantal Lainesse, Al Chicoine","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":9429,"journal":{"name":"Canadian Veterinary Journal-revue Veterinaire Canadienne","volume":"67 5","pages":"578-586"},"PeriodicalIF":1.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13142068/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147834105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Veterinary Medical Ethics.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":9429,"journal":{"name":"Canadian Veterinary Journal-revue Veterinaire Canadienne","volume":"67 5","pages":"491-493"},"PeriodicalIF":1.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13142052/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147834134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Providing veterinary care to food animals considered Minor Uses - Minor Species (MUMS).","authors":"Robert Tremblay","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":9429,"journal":{"name":"Canadian Veterinary Journal-revue Veterinaire Canadienne","volume":"67 4","pages":"473-475"},"PeriodicalIF":1.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13040485/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147608236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hemochromatosis of unknown origin in a young adult dog.","authors":"Ava Arends, Roman Koziy, Enrique Aburto, Vanessa E Cowan","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Hemochromatosis is an uncommon condition in dogs. This report describes hemochromatosis of unknown origin in a dog breed not previously identified as predisposed to the condition. A 3-year-old spayed female German shepherd crossbred dog was presented to a local Saskatchewan veterinary clinic with weight loss, muscle wasting, chronic vomiting, diarrhea, and ascites of ~5 to 6 mo duration. The dog was treated symptomatically and was prescribed medication for potential liver failure. Due to poor response to treatment, the owners elected humane euthanasia. The dog was submitted for necropsy at Prairie Diagnostic Services (Western College of Veterinary Medicine, Saskatoon, Saskatchewan). Necropsy revealed hepatic cirrhosis indicated by severe portal bridging fibrosis and nodular regeneration with iron accumulation (hemosiderin) within the hepatocytes and Kupffer cells. Hemosiderin granules were also identified within the lymph nodes, pancreas, and kidneys. Toxicology testing revealed a highly elevated hepatic iron concentration that was subsequently interpreted as toxic (6479 ppm, wet weight basis). A diagnosis of hemochromatosis was made based on clinical history, gross necropsy findings, elevated hepatic iron concentration, and parenchymal hemosiderin deposition pattern in the liver. Given the lack of chronic exposure to iron, primary hemochromatosis was suspected. An underlying genetic cause was a possible etiology. Key clinical message: This case demonstrates the potential of hemochromatosis as a differential diagnosis for chronic liver disease. Due to currently limited noninvasive antemortem testing options and the potential for development of hepatic cirrhosis, early diagnosis and treatment of hemochromatosis is challenging.</p>","PeriodicalId":9429,"journal":{"name":"Canadian Veterinary Journal-revue Veterinaire Canadienne","volume":"67 4","pages":"406-413"},"PeriodicalIF":1.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13040491/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147608285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sinonasal <i>Nocardia farcinica</i> in a cat with comorbidities.","authors":"Allison Foster, Moira Kerr, Jasmine Gu","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A 15-year-old spayed female domestic shorthair cat was referred because of a chronic history of swelling over the right eye that had progressed to an open, exudative wound. The lesion had not responded to prolonged antimicrobial treatments that were chosen based on superficial culture results. Before this development, the cat had been diagnosed with International Renal Interest Society (IRIS) stage 2 chronic kidney disease with no other significant health issues. Computed tomography revealed fluid to soft-tissue attenuating material in the sinonasal cavities and concurrent bony lysis. Cytology and biopsy of the frontal sinus cavity were suggestive of nocardiosis, which culture confirmed as <i>Nocardia farcinica</i>. Treatment using sulfonamide antibiotics was instituted and resulted in resolution of the clinical signs but did not provide a cure. The cat spontaneously died 1 y following the start of therapy due to causes unrelated to the <i>N. farcinica</i> infection, as confirmed by necropsy. Key clinical message: <i>Nocardia</i> spp. sinonasal infections are rare in small-animal patients but should be considered in cases of rhinosinusitis not responsive to empirical therapy. This report details management of a case of sinonasal nocardiosis in a cat with comorbidities.</p>","PeriodicalId":9429,"journal":{"name":"Canadian Veterinary Journal-revue Veterinaire Canadienne","volume":"67 4","pages":"427-432"},"PeriodicalIF":1.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13040503/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147608297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}