Advanced biomedical research最新文献_第10页

Comparison of Endometrial Polyp Characteristics in Transvaginal Sonography and Hysteroscopy in Predicting Endometrial Malignancies in Premenopausal and Postmenopausal Women. 经阴道超声检查和宫腔镜检查在预测绝经前和绝经后妇女子宫内膜恶性肿瘤方面的子宫内膜息肉特征比较。

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Advanced biomedical research Pub Date : 2024-04-27 eCollection Date: 2024-01-01 DOI: 10.4103/abr.abr_264_21

Safoura Rouholamin, Parisa Irannezhad, Maryam Hashemi

{"title":"Comparison of Endometrial Polyp Characteristics in Transvaginal Sonography and Hysteroscopy in Predicting Endometrial Malignancies in Premenopausal and Postmenopausal Women.","authors":"Safoura Rouholamin, Parisa Irannezhad, Maryam Hashemi","doi":"10.4103/abr.abr_264_21","DOIUrl":"10.4103/abr.abr_264_21","url":null,"abstract":"Background: Hysteroscopy is known as the gold standard for endometrial polyps diagnosis and its findings on vascularity, size, and number of polyps can indicate malignancy, but it is a relatively expensive method with some complications. Ultrasound is a common part of the gynecological examination, and with technological advances, its ability to predict pathological outcomes has increased. This study aimed to determine the accuracy of ultrasound in diagnosing the characteristics of endometrial polyps.Materials and methods: This diagnostic value study was performed on 300 premenopausal and postmenopausal women over 40 years of age with endometrial polyps referred to Alzahra and Beheshti hospitals in Isfahan. The characteristics of endometrial polyps were evaluated by transvaginal ultrasonography and hysteroscopy and biopsy specimens were sent for pathological evaluations.Results: In this study, 103 premenopausal women and 197 postmenopausal women were evaluated. Malignancy was confirmed by pathology in 4 premenopausal women (2%) and 2 postmenopausal women (2%). In both hysteroscopy and ultrasound methods, the frequency of vascularity was significantly different in postmenopausal and premenopausal women, but the other features of the polyp were not significantly different in them. Ultrasonic sensitivity in detecting the presence of vascularity, polyps larger than 1.5 mm, more than 1 polyp, and the presence of pedicle were 39.04, 57.38%, 91.93 and 94.95%, respectively, its specificity were 98.94, 36.47, 99.57 and 98.89% respectively.Conclusion: A comparison of the characteristics of polyps in both ultrasound and hysteroscopy methods shows that hysteroscopy has been more effective in diagnosing malignancy and ultrasound has not have acceptable sensitivity in diagnosing size and vascularity.","PeriodicalId":94292,"journal":{"name":"Advanced biomedical research","volume":"13 ","pages":"27"},"PeriodicalIF":0.7,"publicationDate":"2024-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11373719/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142134979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association between Dietary Intake, Profibrotic Markers, and Blood Pressure in Patients with Chronic Kidney Disease. 慢性肾脏病患者的膳食摄入量、组织坏死标志物和血压之间的关系

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Advanced biomedical research Pub Date : 2024-04-27 eCollection Date: 2024-01-01 DOI: 10.4103/abr.abr_204_23

Abbas Mohtashamian, Alireza Soleimani, Hamid Reza Gilasi, Nejat Kheiripour, Seyed Masoud Moeini Taba, Nasrin Sharifi

{"title":"Association between Dietary Intake, Profibrotic Markers, and Blood Pressure in Patients with Chronic Kidney Disease.","authors":"Abbas Mohtashamian, Alireza Soleimani, Hamid Reza Gilasi, Nejat Kheiripour, Seyed Masoud Moeini Taba, Nasrin Sharifi","doi":"10.4103/abr.abr_204_23","DOIUrl":"10.4103/abr.abr_204_23","url":null,"abstract":"Background: Among profibrotic and oxidant factors, matrix metalloproteinases (MMPs) and advanced glycation end products (AGEs) have a major impact on the progression of chronic kidney disease (CKD). However, very limited studies evaluated the relationships between nutrient intake and the mentioned factors in patients with CKD. Therefore, the present study aimed to investigate the correlation between dietary intake and the levels of MMPs, AGEs, and blood pressure (BP) in these patients.Materials and methods: This cross-sectional study was performed on 90 patients with CKD (stages 2-5). To evaluate the dietary intake of patients, three days of 24-hour food recall were completed through face-to-face and telephone interviews. Measurement of MMP-2 and MMP-9 concentration was done by enzyme-linked immunosorbent assay. The fluorimetric technique was used to measure the total serum AGEs.Results: The patients' average dietary intake of sodium, potassium, phosphorus, energy, and protein was 725 mg/day, 1600 mg/day, 703 mg/day, 1825 kcal/day, and 64.83 g/day, respectively. After adjustment of confounding variables, a significant inverse relationship was observed between dietary intake of insoluble fiber and serum levels of MMP-2 (β = -0.218, P = 0.05). In addition, a significant positive relationship was found between molybdenum (Mo) intake and diastolic BP (β =0.229, P = 0.036).Conclusion: A higher intake of insoluble fiber might be associated with lower serum levels of MMP-2. Also, a higher Mo intake can be correlated to a higher DBP in patients with CKD. It is suggested to conduct future studies with longitudinal designs and among various populations to better elucidate the observed relationships.","PeriodicalId":94292,"journal":{"name":"Advanced biomedical research","volume":"13 ","pages":"29"},"PeriodicalIF":0.7,"publicationDate":"2024-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11373720/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142134910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigating the Involvement of Mediastinal Lymph Nodes in Patients with Papillary Thyroid Carcinoma. 调查甲状腺乳头状癌患者纵隔淋巴结的受累情况

IF 0.7

Advanced biomedical research Pub Date : 2024-04-27 eCollection Date: 2024-01-01 DOI: 10.4103/abr.abr_128_21

Sayed Abbas Tabatabaei, Mohsen Kolahdouzan, Sayed Esmaeil Tabatabaei

{"title":"Investigating the Involvement of Mediastinal Lymph Nodes in Patients with Papillary Thyroid Carcinoma.","authors":"Sayed Abbas Tabatabaei, Mohsen Kolahdouzan, Sayed Esmaeil Tabatabaei","doi":"10.4103/abr.abr_128_21","DOIUrl":"10.4103/abr.abr_128_21","url":null,"abstract":"Background: Papillary thyroid carcinoma (PTC) is also the most common endocrine malignancy. In the present study, we aimed to evaluate the metastasis pattern of upper mediastinal lymph node involvement in patients with PTC.Materials and methods: This is a descriptive cross-sectional study that was performed in 2020 in Isfahan, Iran, on 73 patients with PTC who were candidates for total thyroidectomy. Demographic data including age and gender were collected. The frequency distribution of upper mediastinal lymph node involvements and their relationships with mass size, gender, and age, location of tumor in the thyroid gland and involvement of lateral lymph nodes in the neck were evaluated.Results: The mean mass size was 17.27 mm. The most involved thyroid lobe in patients with upper mediastinal lymph node involvement was the right lobe (16.5%). In terms of mediastinal lymph node involvement, there were no significant relationships between the two sexes (P = 0.161), primary mass size (P = 0.151), and thyroid mass location (P = 0.739) with mediastinal lymph node involvement. There was a significant relationship between lateral lymph node involvement of the neck (P = 0.007) and age groups (P = 0.042) with involvement of the upper mediastinal lymph nodes. Based on our results, the upper mediastinal lymph node involvement was more frequent among patients under 40 years of age.Conclusion: Upper mediastinal lymph node metastasis in PTC was significantly more frequent in cases with younger ages (lower than 40 years) and involvements of lateral lymph nodes in the neck.","PeriodicalId":94292,"journal":{"name":"Advanced biomedical research","volume":"13 ","pages":"26"},"PeriodicalIF":0.7,"publicationDate":"2024-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11373704/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142134982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of Histological Chorioamnionitis in Pre-Term Delivery with and without Pre-Term Rupture of Membrane. 有胎膜早破和无胎膜早破的早产儿绒毛膜羊膜炎组织学比较

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Advanced biomedical research Pub Date : 2024-04-27 eCollection Date: 2024-01-01 DOI: 10.4103/abr.abr_300_21

Zahra Shahshahan, Elahe Zarean, Samaneh Jahanfar, Pegah Hedayat

{"title":"Comparison of Histological Chorioamnionitis in Pre-Term Delivery with and without Pre-Term Rupture of Membrane.","authors":"Zahra Shahshahan, Elahe Zarean, Samaneh Jahanfar, Pegah Hedayat","doi":"10.4103/abr.abr_300_21","DOIUrl":"10.4103/abr.abr_300_21","url":null,"abstract":"Background: Histological chorioamnionitis (HCA) is a histologic response to intra-uterine inflammation that is usually confirmed by pathology examination after pre-term delivery and characterized by acute granulocyte infiltration into the fetal-maternal or fetal tissues. This study aimed to compare the HCA in pre-term delivery with and without pre-term rupture of membrane for assessment of its role on early neonatal outcomes and fetal heart rate patterns.Materials and methods: This case-control study was conducted on placenta, chorionamnion, and cord of 100 cases with and without pre-term rupture of membrane between 28 0/7 and 36 6/7 weeks delivered between March 2018 and February 2021. The kind of delivery, gestational age, neonatal intensive care unit admission, a 5 min Apgar score <7, and fetal heart rate patterns in two groups with and without HCA were assessed.Results: The odds ratio (OR) for HCA was adjusted for fetal heart rate patterns, gestational age, and delivery mode (vaginal delivery or cesarean section). Vaginal delivery, gestational age, neonatal intensive care unit admission, and a 5 min Apgar score <7 were associated with HCA [OR: 2.4, 95% confidence interval (CI): 1.2-9.5, P < 0.05; OR: 0.8, 95% CI: 0.5-1.1, P < 0.05; OR: 1.1, 95% CI: 0.6-2.1, P < 0.05; and OR: 0.9, 95% CI: 0.7-1.3, P < 0.05), respectively. However, there were no specific fetal heart rate patterns associated with HCA.Conclusion: Placental histology examination in pre-term infants with low Apgar scores may be useful to investigate the association between neonatal complications in pre-term delivery and asymptomatic chorioamnionitis.","PeriodicalId":94292,"journal":{"name":"Advanced biomedical research","volume":"13 ","pages":"33"},"PeriodicalIF":0.7,"publicationDate":"2024-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11373726/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142134980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of Pre_Operation Desogestrel Estradiol in Endometrial Preparation at Hysteroscopic Polypectomy. 宫腔镜息肉切除术前去氧孕烯雌二醇对子宫内膜准备的影响

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Advanced biomedical research Pub Date : 2024-04-27 eCollection Date: 2024-01-01 DOI: 10.4103/abr.abr_227_21

Farahnaz Mardanian, Ferdous Mehrabian, Safura Rouholamin, Somayeh Izadpanahi, Maryam Hashemi

{"title":"Effects of Pre_Operation Desogestrel Estradiol in Endometrial Preparation at Hysteroscopic Polypectomy.","authors":"Farahnaz Mardanian, Ferdous Mehrabian, Safura Rouholamin, Somayeh Izadpanahi, Maryam Hashemi","doi":"10.4103/abr.abr_227_21","DOIUrl":"10.4103/abr.abr_227_21","url":null,"abstract":"Background: Hysteroscopic surgery is a common gynecologic process in many conditions. Endometrial thinning is the main successful key for this process associated with many preoperative preparations. This study aimed to evaluate DE (Desogestrel-estradiol) to reduce endometrial thickness in comparison with the control group.Materials and methods: This Randomized clinical trial was done on the patients candidate for polypectomy that were randomly divided into two groups of intervention and control; the first group received DE OCP (oral contraceptive pill with 30 microgram Ethinyl estradiol + 150 micro gram Desogestrel) once daily from the 1st to 5th day of the menstrual cycle for 21 days and then in the first day of next menstruation cycle, the drug was used up to one day before hysteroscopy done in the 5th to 8th day of the cycle. The second group received no drugs. Hysteroscopy was done in the early follicular phase in both groups and all the subjects received one dosage of Misoprostol a night before surgery.Results: There were no significant differences between the parity, polyp size, and BMI (Body Mass Index) in the two groups. The mean duration of surgery, mean endometrial thickness before hysteroscopy, the quality of endometrial tissue, and surgeon satisfaction were significantly difference between the two groups. However, the quality of the surgeon's vision in the intervention group was better than the control group but there was no significant difference between the two groups.Conclusion: Pre-operation endometrial thinning by oral contraceptives such as DE could be an effective method and reduce the duration of surgery.","PeriodicalId":94292,"journal":{"name":"Advanced biomedical research","volume":"13 ","pages":"32"},"PeriodicalIF":0.7,"publicationDate":"2024-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11373727/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142134981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Compare the GCS and the Rotterdam CT Score in Predicting the Mortality and Disability of Patients with Traumatic Brain Injury. 比较 GCS 和鹿特丹 CT 评分在预测创伤性脑损伤患者死亡率和残疾程度方面的作用。

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Advanced biomedical research Pub Date : 2024-04-27 eCollection Date: 2024-01-01 DOI: 10.4103/abr.abr_453_23

Mehdi Mahmoodkhani, Parham Behfarnia, Bahram Aminmansour

{"title":"Compare the GCS and the Rotterdam CT Score in Predicting the Mortality and Disability of Patients with Traumatic Brain Injury.","authors":"Mehdi Mahmoodkhani, Parham Behfarnia, Bahram Aminmansour","doi":"10.4103/abr.abr_453_23","DOIUrl":"10.4103/abr.abr_453_23","url":null,"abstract":"Background: Given the dearth of extensive research comparing the Glasgow Coma Scale with the Rotterdam scoring system for predicting mortality in trauma patients, this study was conducted to determine which scale provides a more realistic prediction of mortality in trauma patients after three months.Materials and methods: This observational study was performed at Kashani Hospital in Isfahan, Iran. Patients with TBI who were admitted between February 2022 and February 2023 were included in the study. Approval from the Ethical Committee of Isfahan University of Medical Sciences was obtained prior to conducting this study.Results: We included 152 adult patients who completed the GOS-E and the QOLIBRI-OS three-month post-injury. The median age was 35 years (IQR = 17-70). Most patients 139 (91.4%) were classified as having a severe TBI.Conclusion: The results of the present study showed that both the use of GCS and Rotterdam CT scores can be effective in predicting the three-month mortality and QOLIBRI-OS scores of patients, with the difference that the predictive power of the three-month Rotterdam CT score is greater than that of the GCS.","PeriodicalId":94292,"journal":{"name":"Advanced biomedical research","volume":"13 ","pages":"35"},"PeriodicalIF":0.7,"publicationDate":"2024-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11373729/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142134978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Proposed Mechanisms for the Relationship between Periodontal Diseases and the Severity of Covid-19: Common Pathogens, Inflammatory Mediators, and Risk Factors. 牙周病与 Covid-19 严重程度之间关系的拟议机制：常见病原体、炎症介质和风险因素。

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Advanced biomedical research Pub Date : 2024-04-27 eCollection Date: 2024-01-01 DOI: 10.4103/abr.abr_116_23

Elham Keykha, Leila Khodadadifard, Mahdieh-Sadat Moosavi, Yaser Fathi, Samira Hajisadeghi

{"title":"Proposed Mechanisms for the Relationship between Periodontal Diseases and the Severity of Covid-19: Common Pathogens, Inflammatory Mediators, and Risk Factors.","authors":"Elham Keykha, Leila Khodadadifard, Mahdieh-Sadat Moosavi, Yaser Fathi, Samira Hajisadeghi","doi":"10.4103/abr.abr_116_23","DOIUrl":"10.4103/abr.abr_116_23","url":null,"abstract":"Periodontal disease (PD) is a chronic inflammatory disease with some cytokine involvement, associated with several risk factors such as diabetes, obesity, etc., Corona Virus Disease 2019 (COVID-19), a new viral infection, also appears to be related to cytokine storm and similar risk factors. In this review, we intend to evaluate the possible relationship between PD and COVID-19. For data collection, English literature was searched in databases including PubMed and Google Scholar. The keywords searched were COVID-19, SARS-CoV-2, PD, respiratory Impact of Oral pathogens on respiratory diseases: Epidemiological studies indicated that oral pathogens are related to acute and chronic lung disease, and dental plaque is a likely reservoir for respiratory pathogens. Viral presence in the periodontal pocket: SARS-CoV-2 may be released from infected periodontal cells into periodontal pockets. Common inflammatory mediators: Several studies showed that the serum levels of interleukins (IL)-1, 6, 17, etc., increase in most patients with severe COVID-19. C-reactive protein (CRP) and endothelin 1(ET-1) may also be related to COVID-19 progression, and these mediators also increase in periodontitis. Common risk factors: Due to studies, diabetes mellitus (DM), obesity, aging, and male sex are the most important risk factors common between PDs and COVID-19 and may affect treatment outcomes and prognosis. PD seems to play a significant role in exacerbating COVID-19 and even affects the mortality rate of disease.","PeriodicalId":94292,"journal":{"name":"Advanced biomedical research","volume":"13 ","pages":"28"},"PeriodicalIF":0.7,"publicationDate":"2024-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11373721/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142134984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Compliance and Lifestyle of Children with Celiac Disease in the Iranian Children. 伊朗儿童乳糜泻患者的依从性和生活方式

Advanced biomedical research Pub Date : 2024-04-27 eCollection Date: 2024-01-01 DOI: 10.4103/abr.abr_247_21

Mandana Rafeey, Robabeh Ghergherehchi, Zeinab Nikniaz, Maryam Shoaran, Amaneh Hosseinalizadeh

{"title":"Compliance and Lifestyle of Children with Celiac Disease in the Iranian Children.","authors":"Mandana Rafeey, Robabeh Ghergherehchi, Zeinab Nikniaz, Maryam Shoaran, Amaneh Hosseinalizadeh","doi":"10.4103/abr.abr_247_21","DOIUrl":"10.4103/abr.abr_247_21","url":null,"abstract":"Background: Celiac disease is popular and needs a proper and constant gluten-free diet. However, data on the experience of the disease by children are insufficient. A few children have difficulty adjusting their lifestyles, and gluten-free foods are difficult for them. The present study aimed to find influential factors in the growth disorders and nonresponse to the treatment diet in celiac patients.Materials and methods: We gave a list of all children with celiac disease to the project manager and according to the criteria extracted additional information from their files. Duodenal biopsies on 382 patients with suspected celiac disease and 93 patients with positive pathology were included in the study, regardless of antibody and genetic titer, then analyzed their information using appropriate statistical tests.Results: The mean age of individuals was 9.48 ± 3.88, and 35 were male and 58 female. At the age of <5, there was more growth disorder than other age groups. The recovery percentage in short stature was significantly better in children with higher marches, and they responded better to the treatment regimen. Individuals with comorbidities had higher anti-tTG and lower Hb levels, higher incidence of growth disorder, did not respond to the treatment regimen. Those with a first-degree relative with celiac disease had a lower growth disorder than others.Conclusion: Identifying and correcting nutritional disorders in patients with celiac disease need to evaluate persistent symptoms and identify their causes to plan appropriate treatment and follow-up of patients with celiac disease step by step and continuously.","PeriodicalId":94292,"journal":{"name":"Advanced biomedical research","volume":"13 ","pages":"25"},"PeriodicalIF":0.0,"publicationDate":"2024-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11132196/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141162975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Longitudinal Examination of Blood Sugar Dynamics in Diabetes and Non-Diabetes Using Growth Curve Model: The Sabzevar Persian Cohort Study. 利用增长曲线模型对糖尿病和非糖尿病患者血糖动态的纵向研究：Sabzevar 波斯队列研究》。

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Advanced biomedical research Pub Date : 2024-04-27 eCollection Date: 2024-01-01 DOI: 10.4103/abr.abr_406_23

Yaser Tabarraei, Abbas Ali Keshtkar, Mir Saeed Yekaninejad, Najme Rahimi, Yousef Dowlatabadi, Kamal Azam

{"title":"A Longitudinal Examination of Blood Sugar Dynamics in Diabetes and Non-Diabetes Using Growth Curve Model: The Sabzevar Persian Cohort Study.","authors":"Yaser Tabarraei, Abbas Ali Keshtkar, Mir Saeed Yekaninejad, Najme Rahimi, Yousef Dowlatabadi, Kamal Azam","doi":"10.4103/abr.abr_406_23","DOIUrl":"10.4103/abr.abr_406_23","url":null,"abstract":"Background: Diabetes mellitus is a chronic metabolic disorder with substantial implications for public health. Understanding the factors influencing blood sugar fluctuations is crucial for effective diabetes management and prevention. This study aimed to evaluate factors associated with blood sugar changes in diabetic patients and healthy individuals attending the Sabzevar Persian Cohort Center, employing the growth curve model.Materials and methods: Data related to 589 diabetic patients and 589 non-diabetic patients participating in the Persian cohort study of Sabzevar were used. Due to the repetition of blood sugar measurements for each individual over time, we use the conditional latent growth curve model to examine intra-individual changes and variables that affect these changes over time.Results: The linear latent growth curve model, fitted with independent variables, exhibited a superior fit. The slope of the line for the diabetic group was measured at 1.78, while for the non-diabetic group, it was estimated to be -0.29. Within the diabetic group, the influence of age, the presence of fatty liver, and history of congenital heart disease (CHD) had a significant impact on the baseline (the intercept), and the effect of body mass index (BMI) on the changing trend of the response variable (slope) was also significant. In the non-diabetic group, significant effects were observed for age variables, BMI, family history of diabetes, and history of stroke in the family.Conclusion: Overall, the linear latent growth curve model showed good performance in the evaluation of the factors related to blood sugar changes in diabetic patients and healthy people.","PeriodicalId":94292,"journal":{"name":"Advanced biomedical research","volume":"13 ","pages":"30"},"PeriodicalIF":0.7,"publicationDate":"2024-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11373718/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142134909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Relationship Between Iron and Zinc Deficiency and Aphthous Stomatitis: A Systematic Review and Meta-Analysis. 缺铁和缺锌与口腔炎的关系：系统回顾与元分析》。

IF 0.7

Advanced biomedical research Pub Date : 2024-04-27 eCollection Date: 2024-01-01 DOI: 10.4103/abr.abr_41_22

Nakisa Torabinia, Saba Asadi, Mohammad J Tarrahi

{"title":"The Relationship Between Iron and Zinc Deficiency and Aphthous Stomatitis: A Systematic Review and Meta-Analysis.","authors":"Nakisa Torabinia, Saba Asadi, Mohammad J Tarrahi","doi":"10.4103/abr.abr_41_22","DOIUrl":"10.4103/abr.abr_41_22","url":null,"abstract":"Background: Recurrent aphthous stomatitis (RAS) is known as the most common ulcerative lesion in the oral mucosa. Aphthous has an unknown etiology and is considered a multifactorial disease. This study was conducted to investigate the relationship between iron and zinc deficiency and the occurrence of RAS.Materials and methods: This systematic review and metaanalysis was performed according to the Preferred Reporting Items for Systematic Reviews and Metaanalyses (PRISMA) guidelines. Data were obtained through an electronic search in international databases, including PubMed, Medline, Embase, ISI Web of Science, Scopus, Springer, ProQuest, ScienceDirect, Clinical Key, and Google Scholar, and domestic Persian databases, including SID, Magiran, and Iran Medex, until April 2021. New-castle Ottawa Scale (NOS) was used to determine the eligibility of studies by evaluating the title and summary of the articles and a partial evaluation of the full text. Comprehensive Metaanalysis (CMA) software was used for data analysis.Results: Initially, a total of 1383 articles were retrieved, of which 941 were duplicate studies. Further, 384 studies were excluded after evaluation of the title and abstract, and 36 studies were excluded after considering the inclusion and exclusion criteria. Finally, 22 articles were included in the metaanalysis. The standardized mean difference value was -0.421 (-0.623--0.20) for iron factor, -0.309 (-0.463--0.154) for iron factor in men, -0.483 (-0.375--0373) for iron factor in women, and -0.955 (-0.282--1.628) for the zinc factor.Conclusion: In general, the serum iron level (in general, in male and female patients separately) and the zinc serum level in patients with RAS were significantly lower than those of healthy people.","PeriodicalId":94292,"journal":{"name":"Advanced biomedical research","volume":"13 ","pages":"31"},"PeriodicalIF":0.7,"publicationDate":"2024-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11373730/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142134985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0