Actas urologicas espanolas最新文献

{"title":"Does preoperative alpha-blocker use affect the results of flexible ureterorenoscopy?","authors":"A Akinci, A Sanci, M Babayigit, C Gogus","doi":"10.1016/j.acuroe.2025.501836","DOIUrl":"10.1016/j.acuroe.2025.501836","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the effect of alpha-blocker therapy during flexible ureterorenoscopy (F-URS) on the treatment of upper urinary tract stones.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on 476 patients who underwent F-URS at the Department of Urology between January 2010 and January 2017. Data collected included alpha-blocker use, stone size, stone location, patient age and gender, success or failure of ureteral access sheath (UAS) placement, ability to reach the stone during the procedure, postoperative stone-free status, and complication rates. Patients were divided into two groups: alpha-blocker users (n = 90, 18.9%) and non-users (n = 386, 81.1%).</p><p><strong>Results: </strong>No significant differences were observed in gender distribution (P = 0.86) or stone size (P = 0.21) between the two groups. Alpha-blocker users had a lower complication rate (P = 0.022), a higher rate of successful stone access during the procedure (P = 0.007), and a higher postoperative stone-free rate (P = 0.01) compared to non-users. Among alpha-blocker users, tamsulosin and silodosin were associated with higher stone clearance rates (P = 0.046 and P = 0.037, respectively).</p><p><strong>Conclusions: </strong>Alpha-blocker therapy during F-URS for upper urinary tract stones is associated with improved outcomes, including higher stone access rates, reduced complications, and increased stone-free rates. These findings suggest that alpha-blockers, particularly tamsulosin and silodosin, may enhance the efficacy and safety of F-URS.</p>","PeriodicalId":94291,"journal":{"name":"Actas urologicas espanolas","volume":" ","pages":"501836"},"PeriodicalIF":0.0,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145056514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"End-of-life and palliative care in patients with metastatic renal cancer.","authors":"G Lendínez-Cano, C Roldán Cumbreras, C B Congregado Ruíz, R A Medina López","doi":"10.1016/j.acuroe.2025.501841","DOIUrl":"10.1016/j.acuroe.2025.501841","url":null,"abstract":"<p><strong>Introduction: </strong>Palliative care is a fundamental component of the comprehensive management of patients with advanced cancer, significantly improving quality of life. Since most patients with metastatic renal cell carcinoma (mRCC) ultimately die from disease progression, end-of-life care represents a key element of quality cancer care. This area can be assessed through specific indicators derived from administrative data.</p><p><strong>Materials and methods: </strong>We conducted a retrospective analysis of patients diagnosed with mRCC who initiated treatment at our center between September 2012 and September 2019, evaluating quality indicators related to end-of-life care.</p><p><strong>Results: </strong>Of the 71 patients identified, 57 had died at the time of analysis (81.6%). A total of 59.6% (95% CI 46.8-72.3) died in hospital, 64% of these in palliative care units. In the last 30 days of life, 22.8% (95% CI 12-33.5) visited the emergency room more than once, while only 1.8% (95% CI 0-5.1) were admitted to the ICU. Contact with palliative care services was documented in 49% (95% CI 36.1-62) of patients, although only 5.3% (95% CI 0-11.1) received early referral (more than 90 days before death).</p><p><strong>Conclusions: </strong>Palliative care in mRCC is underutilized and predominantly offered as end-of-life care, with early referral being exceptional. Multidisciplinary strategies are needed to optimize these services.</p>","PeriodicalId":94291,"journal":{"name":"Actas urologicas espanolas","volume":" ","pages":"501841"},"PeriodicalIF":0.0,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145056488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of treatment efficacy according to RECIP 1.0 criteria in castration-sensitive prostate cancer.","authors":"I Gulturk, C Kapar, E Arslan, M Polat, G B Sonmezoz, D Tural","doi":"10.1016/j.acuroe.2025.501837","DOIUrl":"10.1016/j.acuroe.2025.501837","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the relationship between treatment response and radiological progression-free survival (rPFS) in patients with metastatic castration-sensitive prostate cancer (mCSPC) assessed by PSMA-PET/CT using Response Evaluation Criteria on PSMA (RECIP 1.0) criteria.</p><p><strong>Methods: </strong>In this study, 116 patients were analyzed retrospectively. At the beginning of the treatment and week 12 were PSMA PET/CT images evaluated for changes in total tumor volüme and new lesions. Patients were divided into four groups according to RECIP criteria; complete response (CR), partial response (PR), stable disease (SD) and progressive disease (PD). The primary outcome was the correlation of RECIP criteria with rPFS.</p><p><strong>Results: </strong>Mean age of the patients was 67 years [IQR: 62-72]. Total of 116 patients; 65 (56%) hadPR, 17 (14,6%) SD, 19 (16,3%) PD, and 15 (12%) CR. rPFS was found to be statistically significantly different among these four groups (p < 0.001). RECIP PD was found to be significantly shorter rPFS compared with non-PD (p < 0.001), with an rPFS of 7 months (95% CI: 3.45-10.56). PSA values were measured at nadir in 40 patients and no patient in this group was evaluated as having PD.</p><p><strong>Conclusion: </strong>RECIP criteria have been shown to have prognostic significance in terms of evaluating treatment response and rPFS in mCSPC patients.</p>","PeriodicalId":94291,"journal":{"name":"Actas urologicas espanolas","volume":" ","pages":"501837"},"PeriodicalIF":0.0,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145056522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pharmacological interventions in primary or secondary male anorgasmia: A systematic review.","authors":"M P Gómez-Bueno, A M Diaz-Hung, H A García-Perdomo","doi":"10.1016/j.acuroe.2025.501835","DOIUrl":"10.1016/j.acuroe.2025.501835","url":null,"abstract":"<p><strong>Objective: </strong>To determine the effectiveness and safety of pharmacological therapy in men older than 18 years with primary or secondary anorgasmia in terms of induced orgasm, improvement of the International Index of Erectile Function (IIEF), or Arizona Sexual Experience Scale (ASEX).</p><p><strong>Methods: </strong>we conducted this systematic review according to the recommendations of the Cochrane Collaboration and following the PRISMA Statement. We designed a search strategy in MEDLINE (OVID), EMBASE, LILACS, and the Cochrane Central Register of Controlled Trials (CENTRAL) from inception to the present. We assessed the risk of bias based on the STROBE statement for observational studies and the Rob 2.0 tool for clinical trials.</p><p><strong>Results: </strong>234 patients were included, and 232 were treated with pharmacological therapy in seven studies. Some pathologies reported were a history of prostatectomy, hypogonadism, psychiatric disorders, and use of antidepressants. Cabergoline was the most frequently administered treatment, followed by yohimbine and bupropion. The cabergoline improved orgasm in 66% of the population and yohimbine in 55%. The change in IIEF orgasmic function improved significantly with cabergoline and bupropion (P = <0.001 and P = 0.002). The ASEX improved with pycnogenol and was maintained in months 2,3 and 4 (p ≤ 0.05). The side effects reported were mild in three studies. Amantadine required discontinuation due to depression.</p><p><strong>Conclusion: </strong>Pharmacological therapy with cabergoline, yohimbine, bupropion, and pycnogenol can have a positive effect on the orgasmic function of patients with primary or secondary anorgasmia.</p>","PeriodicalId":94291,"journal":{"name":"Actas urologicas espanolas","volume":" ","pages":"501835"},"PeriodicalIF":0.0,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145056470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Injection density in Rezūm®: Less might not be more. A multicentric international study","authors":"I. Schwartzmann ,&nbsp;S. Secco ,&nbsp;A. Farré ,&nbsp;S. García-Barreras ,&nbsp;E. Fernández ,&nbsp;M. D’Anna ,&nbsp;L. Cindolo ,&nbsp;V. Parejo ,&nbsp;J.I. Tornero ,&nbsp;G. Ferrari ,&nbsp;F. Varvello ,&nbsp;J. Ponce de León ,&nbsp;I. Povo","doi":"10.1016/j.acuroe.2025.501824","DOIUrl":"10.1016/j.acuroe.2025.501824","url":null,"abstract":"<div><h3>Introduction</h3><div>Water Vapor Thermal Therapy (WVTT) has emerged as a minimally invasive surgical therapy (MIST) for benign prostatic obstruction. However, the optimal number of intraprostatic injections remains debated. This study introduces injection density (ID), defined as the number of injections per 10 cc of prostate volume, to assess its impact on treatment failure after WVTT.</div></div><div><h3>Methods</h3><div>Multicentric retrospective study across 11 European centers, analysing patients who underwent WVTT between March 2019 and March 2024. Baseline, surgical, and postoperative data were collected during a 24 months follow-up. The primary outcome was treatment failure, defined as the need for medical or surgical intervention 12 months post-WVTT. Secondary outcomes included sexual function and postoperative complications. Logistic regression was performed across ID cut-off points from 0.75 to 2.5 injections per 10 cc.</div></div><div><h3>Results</h3><div>A total of 722 patients underwent WVTT with a mean age of 64 years and a mean prostate volume of 60 cc. Baseline Qmax was 8.0<!--> <!-->±<!--> <!-->3.6<!--> <!-->mL/s. Intermediate ID cut-off points (1.25–1.75) suggested a protective effect against treatment failure, with 1.75 being the first to reach statistical significance (<em>P</em> <!-->=<!--> <!-->.028). Higher ID cut-off points (2.00–2.50) maintained a protective effect, but only 2.25 reached significance (<em>P</em> <!-->=<!--> <!-->.024). No significant relationship was found between ID and complications. Sexual function remained stable across ID thresholds.</div></div><div><h3>Conclusions</h3><div>Optimizing ID during WVTT may improve success rates without increasing complications or negatively impacting sexual function. These findings support a volumetric approach over the traditional linear injection technique to enhance WVTT outcomes.</div></div>","PeriodicalId":94291,"journal":{"name":"Actas urologicas espanolas","volume":"49 7","pages":"Article 501824"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144769518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical competencies in Urology: Agreement between the perceptions of trainees and practicing professionals in a Latin American country","authors":"J. Scherñuk,&nbsp;M.G. Dorsemaine,&nbsp;J.K. Toapanta Ortega,&nbsp;D. Zimmermann,&nbsp;I.P. Tobia,&nbsp;D. Santillán","doi":"10.1016/j.acuroe.2025.501794","DOIUrl":"10.1016/j.acuroe.2025.501794","url":null,"abstract":"<div><h3>Introduction</h3><div>Consensus remains lacking on which surgeries should be deemed essential for general urologists and which should be reserved for subspecialists. This study aims to compare the perceptions of urology trainees (Trainees) and practicing urologists (PractUrol) regarding the relevance of surgeries for independent practice and subspecialist training.</div></div><div><h3>Methods</h3><div>Cross-sectional comparative study on Trainees and PractUrol from a Latin-American country. Participants completed a Google Forms® questionnaire on 56 urological surgeries in September–October 2023, categorizing each as Essential Index (E-index), Supervised Index (Sup-index), or Subspecialty (Subspec). Statistical comparisons were performed using Chi-square or Fisher’s exact tests with Bonferroni correction.</div></div><div><h3>Results</h3><div>Among 138 participants (109 PractUrol, 29 Trainees), 78.6% (44/56) of surgeries showed agreement between groups, with 13 surgeries achieving over 75% concordance. Disagreements were noted for 21.4% (12/56) of surgeries: (1) Microvaricocelectomy, penectomy, DVIU, ureteral reimplantation, and vesicovaginal fistula repair were more often classified as Subspec by Trainees but as E-index by PractUrol. (2) Radical cystectomy with orthotopic diversion and Boari Flap were classified as Subspec by Trainees but as Sup-index by PractUrol. (3) Partial cystectomy, pelvic, and inguinal lymphadenectomy were more frequently deemed Subspec by Trainees. (4) Flexible ureteroscopy was considered E-index by Trainees but Sup-index by PractUrol. (5) Artificial urinary sphincter placement was more often classified as Sup-index by PractUrol.</div></div><div><h3>Conclusion</h3><div>There is substantial agreement on the relevance of urological surgeries between PractUrol and Trainees, including 13 surgeries deemed essential by over 75% of participants. However, differing opinions on 12 surgeries highlight areas for further discussion.</div></div>","PeriodicalId":94291,"journal":{"name":"Actas urologicas espanolas","volume":"49 7","pages":"Article 501794"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144295596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mapping regional disparities in testicular cancer mortality across Spain (2004–2023)","authors":"L. Cayuela ,&nbsp;S. Cabrera Fernández ,&nbsp;R. Roldán Testillano ,&nbsp;M. Ortega Calvo ,&nbsp;A. Cayuela","doi":"10.1016/j.acuroe.2025.501800","DOIUrl":"10.1016/j.acuroe.2025.501800","url":null,"abstract":"<div><h3>Introduction</h3><div>This study investigates testicular cancer (TC) mortality trends and spatial patterns in Spain, utilizing provincial-level spatial analysis to identify high-risk clusters.</div></div><div><h3>Methods</h3><div><span><span>An ecological study was conducted using TC mortality data (ICD-10 code C62) from the Spanish National Institute of Statistics (2004–2023). Age-standardized </span>mortality rates<span> (ASMRs) were calculated using the direct method. Temporal trends were analyzed with joinpoint regression. Spatial patterns were assessed using standardized mortality ratios (SMR), smoothed </span></span>relative risk (RR), and posterior probabilities (PP) through Bayesian hierarchical models. Spatial clustering was examined with Tango’s test and Kulldorff’s likelihood ratio test.</div></div><div><h3>Results</h3><div>A total of 909 TC deaths were recorded, with ASMRs ranging from 0.14 to 0.26 per 1,000,000 inhabitants. No significant temporal trends were observed. Age-specific mortality showed a bimodal distribution, peaking at ages 35–39 and 85+. The highest SMRs were found in Zamora (2.58), Segovia (2.64), and Soria (2.39), while the lowest were in Madrid (0.66) and Barcelona (0.55). Bayesian spatial analysis identified elevated relative risk in Badajoz (RR 1.6), Huelva (RR 1.47), and Sevilla (RR 1.4). Kulldorff’s analysis revealed a high-mortality cluster in southwestern Spain (Huelva, Sevilla, Badajoz), with a secondary cluster extending to neighbouring provinces.</div></div><div><h3>Conclusions</h3><div>While TC mortality in Spain remained stable, significant regional disparities exist. High-risk provinces and mortality clusters highlight potential inequalities in healthcare access, socioeconomic conditions, and environmental exposures.</div></div>","PeriodicalId":94291,"journal":{"name":"Actas urologicas espanolas","volume":"49 7","pages":"Article 501800"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144577507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical profile and risk factors identified in patients with renal cancer in Mexican population","authors":"G. Sánchez-Villaseñor ,&nbsp;E.A. Pérez-Du Pond ,&nbsp;I. Jasso-García ,&nbsp;S.J. Vázquez-Sánchez ,&nbsp;R.C. García-Romero ,&nbsp;J.P. Gómez-Sierra ,&nbsp;M.G. Castillo-Cardiel ,&nbsp;A.S. Álvarez-Villaseñor ,&nbsp;G. Cervantes-Guevara ,&nbsp;E. Cervantes-Pérez ,&nbsp;S. Ramírez-Ochoa ,&nbsp;A. González-Ojeda ,&nbsp;C. Fuentes-Orozco","doi":"10.1016/j.acuroe.2025.501814","DOIUrl":"10.1016/j.acuroe.2025.501814","url":null,"abstract":"<div><h3>Introduction</h3><div>Renal cell carcinoma, ranked 14th in global incidence, is more common in men. Its incidence rates increase with age, peaking in individuals older than 75 years. The classic triad is present in only 17% of cases. Surgical management involves total or partial nephrectomy, both associated with potential complications.</div></div><div><h3>Objective</h3><div>To identify the clinical profile and risk factors in patients with renal cell carcinoma.</div></div><div><h3>Methodology</h3><div>An observational, cross-sectional, and analytical study was conducted on patients with renal cell carcinoma treated surgically in the Urology Department from January 2020 to June 2023. Demographic and clinical characteristics were analyzed in relation to TNM staging, histologic subtype, and morbidity and mortality.</div></div><div><h3>Results</h3><div>Among 83 patients, 48 (57%) were men, with a mean age of 59.2 years (SD 10.5). Hypertension (HTN) and obesity were the most frequent comorbidities, each affecting 37 patients (44.6%). Flank pain (37 patients, 44.6%) and hematuria (23 patients, 27.7%) were the most common manifestations. Age &gt;50 years was associated with advanced stages (<em>p</em> = 0.003, OR 5.744, 95% CI 1.698–19.424), while obesity was associated with a lower risk of advanced stages (<em>p</em> = 0.0042, OR 0.220, 95% CI 0.075–0.648). Complications of open nephrectomy included bleeding in 26 patients (38.8%) and organ injury in 2 patients (2.9%). Mortality was reported in 1 patient.</div></div><div><h3>Conclusion</h3><div>Age &gt;50 years is a risk factor for advanced stages, while obesity is associated with a lower risk. Hematuria and flank pain were common, whereas abdominal mass was rarely reported.</div></div>","PeriodicalId":94291,"journal":{"name":"Actas urologicas espanolas","volume":"49 7","pages":"Article 501814"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144602735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is it truly necessary to achieve complete stone-free status in cases of staghorn calculi?","authors":"G. Freschi ,&nbsp;D.P. Resuto ,&nbsp;R.H. Astolfi ,&nbsp;W.R. Molina ,&nbsp;A. Meller","doi":"10.1016/j.acuroe.2025.501812","DOIUrl":"10.1016/j.acuroe.2025.501812","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>To evaluate long-term outcomes in staghorn stone patients with residual fragments following surgical treatment.</div></div><div><h3>Materials and methods</h3><div>A retrospective study of patients who underwent percutaneous nephrolithotripsy for staghorn stones and long term follow up were divided into two groups: residual stones versus non-residual stones. The occurrence of new stones or fragment growth, infectious events, and renal function were evaluated. Patients with a follow-up period of less than one year were excluded.</div></div><div><h3>Results</h3><div>A total of 87 patients (75.9% female) were included in the study. Of these, 21.8% were stone-free, while 78.2% exhibited residual fragments with a median size of 7<!--> <!-->mm (3.5–11.5<!--> <!-->mm). The average follow-up period was 27 months (21–36 months). Only 24.1% experienced recurrence or growth of residual fragments, with a median growth of 10<!--> <!-->mm (6−12<!--> <span>mm). Additionally, 14.9% of patients developed urinary infections during the follow-up period. No significant differences were observed between stone-free patients and those with residual fragments in terms of recurrence, residual fragments growth, infectious events, or deterioration in renal function. Similarly, no differences were noted when comparing patients with positive or negative cultures.</span></div></div><div><h3>Conclusions</h3><div>The incidence of recurrence, growth of residual fragments, infectious events, and deterioration of renal function was comparable between patients with and without residual stones. Furthermore, the presence of positive preoperative or intraoperative cultures did not influence these outcomes.</div></div>","PeriodicalId":94291,"journal":{"name":"Actas urologicas espanolas","volume":"49 7","pages":"Article 501812"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144577506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Infrared spectroscopic analysis of urinary stone composition","authors":"X. Han ,&nbsp;Z. Zhang ,&nbsp;P. Yao ,&nbsp;X. Yang","doi":"10.1016/j.acuroe.2025.501810","DOIUrl":"10.1016/j.acuroe.2025.501810","url":null,"abstract":"<div><h3>Objective</h3><div>To assess the composition of urinary stones in Lanzhou area and provide a reference basis for its clinical prevention and treatment.</div></div><div><h3>Methods</h3><div>A total of 1284 patients with urinary stones were included in the study. The differences in the distribution of stone components among different genders and ages were then analyzed.</div></div><div><h3>Results</h3><div>The overall male-to-female ratio of the cases was 3.2:1. The average age of the patients was 45.1 ± 14.0 years old. The ratio between upper and lower urinary tract stones was 7.13:1. Mixed stone composition accounted for the majority, 79.0% (1014/1284), with calcium oxalate monohydrate + calcium oxalate dihydrate + carbonate apatite being the most prevalent at 35% (449/1284), and calcium oxalate monohydrate stones being the most prevalent of the single components at 17.8% (228/1284). Apatite carbonate 62.2% (191/307) and magnesium ammonium phosphate hexahydrate 9.8% (30/307) were significantly higher in female patients compared to apatite carbonate 55.2% (539/977) and 2.8% (27/977) in male patients. Calcium oxalate was significantly more prevalent in patients aged 18–60 years than in patients &lt;18 and ≥60 years. The proportion of patients over the age of 60 with urinary stones (10.4%) was significantly higher than patients in other age groups.</div></div><div><h3>Conclusion</h3><div>Urological stones in Lanzhou area are mainly of mixed type, calcium oxalate monohydrate + calcium oxalate dihydrate + carbonate apatite is the most; with the increase of patient's age, the proportion of uric acid stones increases; the distribution of urinary stone components has significant differences with different genders of patients and different age groups, which is of great significance for clinical prevention and treatment.</div></div>","PeriodicalId":94291,"journal":{"name":"Actas urologicas espanolas","volume":"49 7","pages":"Article 501810"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144602744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}