Actas urologicas espanolas最新文献_第3页

Coinfection of monkeypox, COVID-19 and syphilis in a PrEP using MSM: a case report from Barcelona 在使用 PrEP 的男男性行为者中同时感染猴痘、COVID-19 和梅毒：来自巴塞罗那的病例报告。

Actas urologicas espanolas Pub Date : 2024-10-01 DOI: 10.1016/j.acuroe.2024.05.011

引用次数: 0

Gender trends at the annual Spanish Urologic Association (AEU) meeting: A review of AEU programmes over a 10-year period (2012–2022) 西班牙泌尿协会（AEU）年会的性别趋势：西班牙泌尿外科协会（AEU）年会的性别趋势：西班牙泌尿外科协会十年计划回顾（2012-2022 年）。

Actas urologicas espanolas Pub Date : 2024-10-01 DOI: 10.1016/j.acuroe.2024.05.005

{"title":"Gender trends at the annual Spanish Urologic Association (AEU) meeting: A review of AEU programmes over a 10-year period (2012–2022)","authors":"","doi":"10.1016/j.acuroe.2024.05.005","DOIUrl":"10.1016/j.acuroe.2024.05.005","url":null,"abstract":"<div><h3>Introduction</h3><div>Gender equity in urological meetings is pivotal for fostering diversity and inclusivity in the field. This study aims to evaluate the representation of Spanish urologist and regional disparities, and to assess its alignment with the demographic composition of the urological community.</div></div><div><h3>Materials and methods</h3><div>All urology meetings organized by the AEU between January 2012 and December 2022 were reviewed, including meeting information and details of the faculty. Additionally, we analysed geographic distribution of speakers across 17 different regions. Gender demographics were obtained disaggregating data by sex and year from the Organización Médica Colegial de España (OMC) and from those urologists affiliated to the AEU.</div></div><div><h3>Results</h3><div>Analysing 52 AEU congresses held from 2012 to 2022, encompassing 3,407 speakers, the study found that 95.25% of speakers were from Spain and 89.6% were male speakers. Over the years, there was a positive trend in female speaker representation, increasing by 1.1% annually, slightly lagging the 1.8% annual rise in the number of female urologists in Spain. In specific subfields like functional, transplantation, and oncology sessions, the study revealed a higher representation of women, indicating focused efforts in these areas. Geographically, Madrid, Catalonia and Andalusia exhibited the highest representation.</div></div><div><h3>Conclusions</h3><div>Although there was a positive trend towards an increased participation of female urologists in Spanish urological meetings, it fails to accurately reflect the proportional increase in the number of women entering the urology profession in recent years. This study underscores the importance of ongoing efforts to ensure diverse and balanced representation in urological forum.</div></div>","PeriodicalId":94291,"journal":{"name":"Actas urologicas espanolas","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140913639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence of DNA-Repair Gene mutations in Mexican men with prostate cancer 墨西哥男性前列腺癌患者 DNA 修复基因突变的发生率。

Actas urologicas espanolas Pub Date : 2024-10-01 DOI: 10.1016/j.acuroe.2024.05.009

{"title":"Prevalence of DNA-Repair Gene mutations in Mexican men with prostate cancer","authors":"","doi":"10.1016/j.acuroe.2024.05.009","DOIUrl":"10.1016/j.acuroe.2024.05.009","url":null,"abstract":"<div><h3>Introduction and objective</h3><div><span>Mexico reported 26,742 new cases of prostate cancer<span><span> in 2020. Different risk factors have been identified in the pathogenesis of prostate cancer. Among them, </span>genetic factors and alterations or mutations in specific genes have been described in different ethnic groups worldwide. The aim of our study is to report the prevalence of </span></span>germline DNA-repair gene mutations in Mexican patients with prostate cancer.</div></div><div><h3>Material and method</h3><div>We performed germline genetic testing in 50 patients with localized prostate cancer and 50 patients with metastatic prostate cancer. Demographic, clinical, and histopathological data were collected.</div></div><div><h3>Results</h3><div><span>Thirty-seven germline mutations were identified in 32 patients. The most commonly affected genes were </span><em>ATM</em> in 6%, followed by <span><em>FANCA</em></span> (5%), and <em>ATR</em> (4%). <span><span>BRCA2</span></span> mutations were identified in 3%. The frequency of mutations was higher in the metastatic group.</div></div><div><h3>Discussion and conclusion</h3><div><span>The results of our study show different mutations from those reported in different populations or regions. The use of PARP inhibitors<span> is indicated in patients with germline mutations, specifically BRCA2, showing improvement in </span></span>overall survival<span> and progression free survival. To our knowledge, this is the first study reporting the prevalence of mutations in DNA-repair genes in Mexican patients with prostate cancer.</span></div></div>","PeriodicalId":94291,"journal":{"name":"Actas urologicas espanolas","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140913626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The journey of determining PD-L1 expression in muscle-invasive urothelial carcinoma 确定浸润性尿路上皮癌中 PD-L1 的表达：西班牙解剖病理学会的建议。

Actas urologicas espanolas Pub Date : 2024-10-01 DOI: 10.1016/j.acuroe.2024.05.015

引用次数: 0

Consensus document on the implications of standardization of BCG supply in the management of patients with non-muscle-invasive bladder cancer. 卡介苗供应标准化对非肌层浸润性膀胱癌患者治疗的影响共识文件。

Actas urologicas espanolas Pub Date : 2024-09-26 DOI: 10.1016/j.acuroe.2024.09.005

Ó Rodríguez Faba, J M Fernández Gómez, F Guerrero-Ramos, M Álvarez-Maestro, M J Ledo Cepero, M Unda Urzaiz, L Martínez-Piñeiro, J M Cózar Olmo, J Palou Redorta, J L Álvarez-Ossorio

{"title":"Consensus document on the implications of standardization of BCG supply in the management of patients with non-muscle-invasive bladder cancer.","authors":"Ó Rodríguez Faba, J M Fernández Gómez, F Guerrero-Ramos, M Álvarez-Maestro, M J Ledo Cepero, M Unda Urzaiz, L Martínez-Piñeiro, J M Cózar Olmo, J Palou Redorta, J L Álvarez-Ossorio","doi":"10.1016/j.acuroe.2024.09.005","DOIUrl":"10.1016/j.acuroe.2024.09.005","url":null,"abstract":"<p><p>Patients with non-muscle-invasive bladder cancer (NMIBC) in the intermediate and high-risk groups must receive adjuvant treatment with intravesical Bacillus Calmette-Guérin (BCG) following transurethral resection (TUR), as it reduces the risk of recurrence and presumably the risk of progression as well. Optimization of BCG efficacy is achieved by administering maintenance therapy. However, since many immunological aspects of the mechanism of action of BCG in the bladder remain unknown, the implementation of the optimal dose, number of instillations, strains and adequate maintenance regimen over the last decades has been heterogeneous. Additionally, this has hindered the interpretation of efficacy in terms of oncologic outcomes. This, together with the shortages of BCG in recent years, have forced scientific societies to adapt their clinical practice guidelines and modify their protocols of adjuvant treatment with BCG. This includes changes to strains, doses, and maintenance during this period of time. This consensus document evaluates the current status of adjuvant BCG treatment and the implications of BCG supply availability in the treatment of patients with NMIBC. It also addresses the implementation of novel therapies that will improve cancer prognosis and the quality of life of patients with NMIBC in the future.</p>","PeriodicalId":94291,"journal":{"name":"Actas urologicas espanolas","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142335684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical application of the UroLift® prostatic urethral lift in Spain: consensus on the treatment of lower urinary tract symptoms associated with urinary flow obstruction and secondary to benign prostatic hyperplasia (BPH). UroLift® 前列腺尿道提升术在西班牙的临床应用：关于治疗与尿流梗阻相关并继发于良性前列腺增生症 (BPH) 的下尿路症状的共识。

Actas urologicas espanolas Pub Date : 2024-09-23 DOI: 10.1016/j.acuroe.2024.09.004

M Fernández Arjona, L López Martín, L M Herranz Fernández, B Sinues Ojas, J M Campá Bortoló, J Extramiana Cameno, E López Alcina, I Povo Martín, A Budía Alba, G Ordaz Jurado, J M Osca García, M Perán Teruel, V Gimeno Argente, A Navarro Beltrán, J Benejam Gual, Y E Hernández Martínez, C González Enguita

{"title":"Clinical application of the UroLift® prostatic urethral lift in Spain: consensus on the treatment of lower urinary tract symptoms associated with urinary flow obstruction and secondary to benign prostatic hyperplasia (BPH).","authors":"M Fernández Arjona, L López Martín, L M Herranz Fernández, B Sinues Ojas, J M Campá Bortoló, J Extramiana Cameno, E López Alcina, I Povo Martín, A Budía Alba, G Ordaz Jurado, J M Osca García, M Perán Teruel, V Gimeno Argente, A Navarro Beltrán, J Benejam Gual, Y E Hernández Martínez, C González Enguita","doi":"10.1016/j.acuroe.2024.09.004","DOIUrl":"10.1016/j.acuroe.2024.09.004","url":null,"abstract":"<p><p>Benign prostatic hyperplasia (BPH) is an increasingly common pathology in the adult male. BPH increases after the age of 40-45 years, and its management consumes an enormous amount of resources. The UroLift® System is an approved technology designed to treat lower urinary tract symptoms (LUTS) secondary to BPH and is used to perform the prostatic urethral lift (PUL) procedure. Various urology specialists in Spain with experience in PUL have prepared this consensus document. Endorsed by the Spanish Urology Association, its information is based on the most recent findings. The main objective of this document is to disseminate the consensus recommendations among all professionals treating patients with LUTS/BPH. Both primary care physicians and urologists can assess and offer PUL as an effective, minimally invasive treatment.</p>","PeriodicalId":94291,"journal":{"name":"Actas urologicas espanolas","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142335683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessment of changes in sexual function in patients undergoing endoscopic surgery for upper urinary tract lithiasis. 评估接受内窥镜手术治疗上尿路结石患者的性功能变化。

Actas urologicas espanolas Pub Date : 2024-09-21 DOI: 10.1016/j.acuroe.2024.09.003

J Tabares Jiménez, G Bueno Serrano, M P Alcoba García, R González López, B Gómez Jordana, I Mahillo Fernández, C González Enguita

{"title":"Assessment of changes in sexual function in patients undergoing endoscopic surgery for upper urinary tract lithiasis.","authors":"J Tabares Jiménez, G Bueno Serrano, M P Alcoba García, R González López, B Gómez Jordana, I Mahillo Fernández, C González Enguita","doi":"10.1016/j.acuroe.2024.09.003","DOIUrl":"10.1016/j.acuroe.2024.09.003","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the effect of endoscopic surgery on sexual function in patients with upper urinary tract (UUT) lithiasis.</p><p><strong>Material and methods: </strong>We conducted an observational, prospective, longitudinal study with a single cohort of cases undergoing ureteroscopy (URS), retrograde intrarenal surgery (RIRS), or endoscopic combined intrarenal surgery (ECIRS). Patients' sexual response was assessed with questionnaires in the 30 days prior to surgery, and at one and three months after surgery. The International Index of Erectile Function (IIEF-t) was used in male patients, and the Female Sexual Function Index (FSFI) was used in female patients.</p><p><strong>Results: </strong>Seventy patients - 34 men and 36 women - completed the study. Among men, the IIEF-t did not show significant difference between baseline scores (64.1 ± 7.50) and those obtained at 3 months (63.8 ± 9.51), with a non-significant decrease (p = 0.054) at the first month (61.4 ± 10.4). Subdomains did not worsen at 3 months, and desire (IIEF-SD) improved from 7.3 ± 1.9 to 8.0 ± 1.8. Among women, the FSFI-t did not change significantly after surgery: baseline score (27.3 ± 4.1), 1-month score (26.8 ± 3.7) and 3-month score (27.5 ± 4.2). No subdomain worsened at the third month.</p><p><strong>Conclusion: </strong>Endoscopic surgery for UUT is a safe technique in both sexes with no negative effect on sexual function. There are no differences between the baseline IIEF-t and FSFI-t scores and those obtained at 3 months.</p>","PeriodicalId":94291,"journal":{"name":"Actas urologicas espanolas","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142309567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Scientific research productivity in urology: A 20-year bibliometric analysis in Latin America. 泌尿外科的科研生产力：拉丁美洲 20 年文献计量分析。

Actas urologicas espanolas Pub Date : 2024-09-21 DOI: 10.1016/j.acuroe.2024.09.002

G Mendoza-Chuctaya, K Rodrigo-Ramos, P Mendoza-Arana, E Rios-Cadenillas

{"title":"Scientific research productivity in urology: A 20-year bibliometric analysis in Latin America.","authors":"G Mendoza-Chuctaya, K Rodrigo-Ramos, P Mendoza-Arana, E Rios-Cadenillas","doi":"10.1016/j.acuroe.2024.09.002","DOIUrl":"10.1016/j.acuroe.2024.09.002","url":null,"abstract":"<p><strong>Introduction and objectives: </strong>The knowledge generated by scientific research is linked to the development of countries, as it provides the necessary resources to guarantee scientific progress and cost-effective healthcare. For this reason, our study analyzes the trends of scientific publication in urology in Latin America.</p><p><strong>Methods: </strong>A bibliometric analysis was performed. Data collection was carried out using the SCOPUS search engine in April 2023, and the search terms were defined by the authors, including the most common diseases in the specialty of urology. A descriptive analysis of the different characteristics, trends and scientific collaborations was performed. The collaboration networks were plotted using VOSviewer.</p><p><strong>Results: </strong>From 2000 to 2021, Latin American publications in urology amounted to 9135 in scientific journals. Brazil is the country with the greatest scientific production (51.2%) and Chile has the greatest scientific production per million inhabitants. Of the total number of scientific publications, 51.1% were related to prostate cancer, 88.8% were written in English (and 50.2% had non-open access). The country with greatest collaborative research with Latin America was the United States.</p><p><strong>Conclusions: </strong>Scientific output in urology in Latin America has increased substantially over the last 20 years. The most published topic is prostate cancer, most papers are written in English, and the United States takes first place regarding scientific collaboration. However, the proportion of the world's science originated in Latin America is still low and depends on Brazil.</p>","PeriodicalId":94291,"journal":{"name":"Actas urologicas espanolas","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142309568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Why do patients with urinary diversions have an increased risk of bone fracture? A systematic review on risk factors for osteoporosis and bone mineral density loss in this group of patients 为什么尿路改道患者发生骨折的风险会增加？关于该类患者骨质疏松症和骨矿物质密度损失风险因素的系统综述。

Actas urologicas espanolas Pub Date : 2024-09-01 DOI: 10.1016/j.acuroe.2023.11.009

{"title":"Why do patients with urinary diversions have an increased risk of bone fracture? A systematic review on risk factors for osteoporosis and bone mineral density loss in this group of patients","authors":"","doi":"10.1016/j.acuroe.2023.11.009","DOIUrl":"10.1016/j.acuroe.2023.11.009","url":null,"abstract":"<div><h3>Introduction</h3><p><span>Patients undergoing radical cystectomy with </span>urinary diversions (UD) are at increased risk of bone fractures compared to the general population. Although a loss of bone mineral density (BMD) has been described in patients with UD, we still do not know with certainty why these patients follow this tendency.</p></div><div><h3>Objective</h3><p><span>We performed a systematic review<span> of the available literature to analyze the prevalence of osteoporosis and bone alterations in patients with ileal UD and the possible associated </span></span>risk factors.</p></div><div><h3>Evidence acquisition</h3><p>We systematically searched PubMed® and Cochrane Library for original articles published before December 2022 according to PRISMA guidelines.</p></div><div><h3>Evidence synthesis</h3><p><span>A total of 394 publications were identified. We selected 12 studies that met the inclusion criteria with 496 patients included. Six of the twelve studies showed decreased BMD values. Prevalence of osteoporosis was specified in three articles, with values ranging from 0% to 36%. Risk factors such as age, sex, body mass index, </span>metabolic acidosis<span><span> and renal function<span> appear to have an impact on bone tissue reduction, while type of UD, follow-up, 25-hydroxyvitamin D and </span></span>parathormone had less evidence or contradictory data. The heterogeneity of the studies analyzed could led to interpretation bias.</span></p></div><div><h3>Conclusions</h3><p>UD are associated with multiple risk factors for osteoporosis and bone fractures. Identifying patients at highest risk and establishing diagnostic protocols in routine clinical practice are essential to reduce the risk of fractures and the resulting complications.</p></div>","PeriodicalId":94291,"journal":{"name":"Actas urologicas espanolas","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139748039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Why is it necessary to produce a BCG strain in Spain? 为什么必须在西班牙生产卡介苗菌株？

Actas urologicas espanolas Pub Date : 2024-09-01 DOI: 10.1016/j.acuroe.2024.04.003

引用次数: 0