World journal of methodology最新文献

{"title":"Prognostic factors for acute central retinal artery occlusion treated with hyperbaric oxygen: The Hong Kong study report number five.","authors":"Sunny Chi Lik Au, Steffi Shing Yee Chong","doi":"10.5662/wjm.v15.i2.96777","DOIUrl":"10.5662/wjm.v15.i2.96777","url":null,"abstract":"<p><strong>Background: </strong>Central retinal artery occlusion (CRAO) is a potentially blinding disease, and hyperbaric oxygen therapy (HBOT) is becoming increasingly popular with the support of scientific evidence. Despite the presence of various acute management measures, there is no clear evidence on the gold standard treatment for CRAO.</p><p><strong>Aim: </strong>To identify factors and imaging parameters associated with good visual outcome, which guide ophthalmologists in the triage of CRAO patients for HBOT.</p><p><strong>Methods: </strong>Patients who suffered from CRAO and had a symptom onset ≤ 6 h were recruited for a course of HBOT in a tertiary hospital after failing bedside treatment. Patient demographics, onset time, CRAO eye parameters, and past medical history were prospectively collected. Visual outcomes after HBOT were also analyzed.</p><p><strong>Results: </strong>A total of 26 patients were included; the female-to-male ratio was 1:1.6, and the mean age was 67.5 years ± 13.3 years (range 44-89 years). The mean duration of follow-up and mean visual acuity (VA) improvement were 10.0 mo ± 5.3 mo and 0.48 logarithm of minimal angle of resolution (logMAR) ± 0.57 logMAR (approximately 9 letters in ETDRS) (<i>P</i> = 0.0001, <i>Z</i> = -3.67), respectively. The 1 mm zone of central macular thickness (CMT) on optical coherence tomography was not associated with VA changes (<i>P</i> = 0.119); however, the 1-to-3 mm circular rim of CMT was fairly associated (<i>P</i> = 0.02, Spearman's coefficient = 0.45). Complete retinal perfusion time during fundus fluorescein angiography (FFA) was moderately associated (<i>P</i> = 0.01, Spearman's coefficient = 0.58) with visual outcome.</p><p><strong>Conclusion: </strong>A thinner 1-to-3 mm circular rim of CMT, but not the central 1 mm zone, is associated with better visual outcome. A shorter perfusion delay on FFA is also associated with better visual outcome.</p>","PeriodicalId":94271,"journal":{"name":"World journal of methodology","volume":"15 2","pages":"96777"},"PeriodicalIF":0.0,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11612726/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144478421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Magnification: The game changer in dentistry.","authors":"Sachin Chauhan, Radha Chauhan, Prashant Bhasin, Meenu Bhasin","doi":"10.5662/wjm.v15.i2.100937","DOIUrl":"10.5662/wjm.v15.i2.100937","url":null,"abstract":"<p><p>During dental examinations and treatments, many dentists are using magnification to improve their vision. The dental operating microscope serves as the most effective tool for this purpose, enhancing the quality, longevity, and outcome of clinical work. This review will explore the latest research and data on the importance of magnification devices in dentistry, including diagnostic methods, treatment options and ergonomics in specialities such as restorative dentistry, endodontics, pedodontics, periodontics, and prosthodontics. This review aims to provide insights into the optimal magnification for different clinical situations, the specific benefits of dental operating microscopes for each dental branch, and their limitations.</p>","PeriodicalId":94271,"journal":{"name":"World journal of methodology","volume":"15 2","pages":"100937"},"PeriodicalIF":0.0,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11612727/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144478418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Musculoskeletal disorders in nursing staff.","authors":"Agapi Kolovou, Asterios N Gkougkoulias, Nikolaos Stefanou, Elena Manuela Samaila, Maria Tsekoura, Marianna Vlychou, Charalampos Matzaroglou, Zoe H Dailiana","doi":"10.5662/wjm.v15.i2.98043","DOIUrl":"10.5662/wjm.v15.i2.98043","url":null,"abstract":"<p><p>Nursing staff provides patient care in an occupational environment that often imposes challenges that affect significantly the musculoskeletal system. Work-related musculoskeletal disorders are common in nursing stuff and have a negative impact in their professional and daily activities. In the current editorial, the duties of nursing staff, the types of musculoskeletal disorders, the predisposing factors (including factors related to professional tasks/ergonomics and to working schedules, psychological, social and individual factors) and their impact on working ability and quality of life nursing staff are summarized and preventive measures are proposed.</p>","PeriodicalId":94271,"journal":{"name":"World journal of methodology","volume":"15 2","pages":"98043"},"PeriodicalIF":0.0,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11612736/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144478419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Immunohistochemical expression of matrix metalloproteinase-9 and 13 in oral squamous cell carcinoma and their role in predicting lymph node metastasis.","authors":"Bhari Sharanesha Manjunatha, Keshav T Handge, Vandana Sandeep Shah, Yasser Eid Al-Thobaiti, Deepak Gowda Sadashivappa Pateel","doi":"10.5662/wjm.v15.i2.94514","DOIUrl":"10.5662/wjm.v15.i2.94514","url":null,"abstract":"<p><strong>Background: </strong>One of the main characteristics of oral squamous cell carcinoma (OSCC) is that it metastasizes to cervical lymph nodes frequently with a high degree of local invasiveness. A primary feature of malignant tumors is their penetration of neighboring tissues, such as lymphatic and blood arteries, due to the tumor cells' capacity to break down the extracellular matrix (ECM). Matrix metalloproteinases (MMPs) constitute a family of proteolytic enzymes that facilitate tissue remodeling and the degradation of the ECM. MMP-9 and MMP-13 belong to the group of extracellular matrix degrading enzymes and their expression has been studied in OSCC because of their specific functions. MMP-13, a collagenase family member, is thought to play an essential role in the MMP activation cascade by breaking down the fibrillar collagens, whereas MMP-9 is thought to accelerate the growth of tumors. Elevated MMP-13 expression has been associated with tumor behavior and patient prognosis in a number of malignant cases.</p><p><strong>Aim: </strong>To assess the immunohistochemical expression of MMP-9 and MMP-13 in OSCC.</p><p><strong>Methods: </strong>A total of 40 cases with histologically confirmed OSCC by incisional biopsy were included in this cross-sectional retrospective study. The protocols for both MMP-9 and MMP-13 immunohistochemical staining were performed according to the manufacturer's recommendations along with the normal gingival epithelium as a positive control. All the observations were recorded and Pearson's <i>χ</i>² test with Fisher exact test was used for statistical analysis.</p><p><strong>Results: </strong>Our study showed no significant correlation between MMP-9 and MMP-13 staining intensity and tumor size. The majority of the patients were in advanced TNM stages (III and IV), and showed intense expression of MMP-9 and MMP-13.</p><p><strong>Conclusion: </strong>The present study suggests that both MMP-9 and MMP-13 play an important and independent role in OSCC progression and invasiveness. Intense expression of MMP-9 and MMP-13, irrespective of histological grade of OSCC, correlates well with TNM stage. Consequently, it is evident that MMP-9 and MMP-13 are important for the invasiveness and progression of tumors. The findings may facilitate the development of new approaches for evaluating lymph node metastases and interventional therapy techniques, hence enhancing the prognosis of patients diagnosed with OSCC.</p>","PeriodicalId":94271,"journal":{"name":"World journal of methodology","volume":"15 2","pages":"94514"},"PeriodicalIF":0.0,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11612739/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144478417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimizing bone marrow harvesting sites for enhanced mesenchymal stem cell yield and efficacy in knee osteoarthritis treatment.","authors":"Arulkumar Nallakumarasamy, Sandeep Shrivastava, Ravi Velamoor Rangarajan, Naveen Jeyaraman, Avinash Gandi Devadas, Swaminathan Ramasubramanian, Madhan Jeyaraman","doi":"10.5662/wjm.v15.i2.101458","DOIUrl":"10.5662/wjm.v15.i2.101458","url":null,"abstract":"<p><p>Knee osteoarthritis (OA) is a debilitating condition with limited long-term treatment options. The therapeutic potential of mesenchymal stem cells (MSCs), particularly those derived from bone marrow aspirate concentrate, has garnered attention for cartilage repair in OA. While the iliac crest is the traditional site for bone marrow harvesting (BMH), associated morbidity has prompted the exploration of alternative sites such as the proximal tibia, distal femur, and proximal humerus. This paper reviews the impact of different harvesting sites on mesenchymal stem cell (MSC) yield, viability, and regenerative potential, emphasizing their relevance in knee OA treatment. The iliac crest consistently offers the highest MSC yield, but alternative sites within the surgical field of knee procedures offer comparable MSC characteristics with reduced morbidity. The integration of harvesting techniques into existing knee surgeries, such as total knee arthroplasty, provides a less invasive approach while maintaining therapeutic efficacy. However, variability in MSC yield from these alternative sites underscores the need for further research to standardize techniques and optimize clinical outcomes. Future directions include large-scale comparative studies, advanced characterization of MSCs, and the development of personalized harvesting strategies. Ultimately, the findings suggest that optimizing the site of BMH can significantly influence the quality of MSC-based therapies for knee OA, enhancing their clinical utility and patient outcomes.</p>","PeriodicalId":94271,"journal":{"name":"World journal of methodology","volume":"15 2","pages":"101458"},"PeriodicalIF":0.0,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11612723/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144478420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gender disparities and woman-specific trends in Barrett's esophagus in the United States: An 11-year nationwide population-based study.","authors":"Karina Fatakhova, Faisal Inayat, Hassam Ali, Pratik Patel, Attiq Ur Rehman, Arslan Afzal, Muhammad Sarfraz, Shiza Sarfraz, Gul Nawaz, Ahtshamullah Chaudhry, Rubaid Dhillon, Arthur Dilibe, Benjamin Glazebnik, Lindsey Jones, Emily Glazer","doi":"10.5662/wjm.v15.i1.97512","DOIUrl":"10.5662/wjm.v15.i1.97512","url":null,"abstract":"<p><strong>Background: </strong>Barrett's esophagus (BE) is a known premalignant precursor to esophageal adenocarcinoma (EAC). The prevalence rates continue to rise in the United States, but many patients who are at risk of EAC are not screened. Current practice guidelines include male gender as a predisposing factor for BE and EAC. The population-based clinical evidence regarding female gender remains limited.</p><p><strong>Aim: </strong>To study comparative trends of gender disparities in patients with BE in the United States.</p><p><strong>Methods: </strong>A nationwide retrospective study was conducted using the 2009-2019 National Inpatient Sample (NIS) database. Patients with a primary or secondary diagnosis code of BE were identified. The major outcome of interest was determining the gender disparities in patients with BE. Trend analysis for respective outcomes for females was also reported to ascertain any time-based shifts.</p><p><strong>Results: </strong>We identified 1204190 patients with BE for the study period. Among the included patients, 717439 (59.6%) were men and 486751 (40.4%) were women. The mean age was higher in women than in men (67.1 ± 0.4 <i>vs</i> 66.6 ± 0.3 years, <i>P</i> < 0.001). The rate of BE per 100000 total NIS hospitalizations for males increased from 144.6 in 2009 to 213.4 in 2019 (<i>P</i> < 0.001). The rate for females increased from 96.8 in 2009 to 148.7 in 2019 (<i>P</i> < 0.001). There was a higher frequency of obesity among women compared to men (17.4% <i>vs</i> 12.6%, <i>P</i> < 0.001). Obesity prevalence among females increased from 12.3% in 2009 to 21.9% in 2019 (<i>P</i> < 0.001). A lower prevalence of smoking was noted in women than in men (20.8% <i>vs</i> 35.7%, <i>P</i> < 0.001). However, trend analysis showed an increasing prevalence of smoking among women, from 12.9% in 2009 to 30.7% in 2019 (<i>P</i> < 0.001). Additionally, there was a lower prevalence of alcohol abuse, <i>Helicobacter pylori</i> (<i>H. pylori</i>), and diabetes mellitus among females than males (<i>P</i> < 0.001). Trend analysis showed an increasing prevalence of alcohol use disorder and a decreasing prevalence of <i>H. pylori</i> and diabetes mellitus among women (<i>P</i> < 0.001).</p><p><strong>Conclusion: </strong>The prevalence of BE among women has steadily increased from 2009 to 2019. The existing knowledge concerning BE development has historically focused on men, but our findings show that the risk in women is not insignificant.</p>","PeriodicalId":94271,"journal":{"name":"World journal of methodology","volume":"15 1","pages":"97512"},"PeriodicalIF":0.0,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11525896/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143672171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Present status and future directions: Apexification.","authors":"Sachin Chauhan, Radha Chauhan, Prashant Bhasin, Bhavna G Sharaf","doi":"10.5662/wjm.v15.i1.96923","DOIUrl":"10.5662/wjm.v15.i1.96923","url":null,"abstract":"<p><p>The success rate of apexification is primarily determined by multiple factors, including the material used, the size of the open apex compared to the length of the root, and the technique used in each case. The main objective of this review was to provide an update on the present management of open apex to identify factors and circumstances that may influence the success of apexification using different materials and techniques. Future research on apexification should focus on how to treat open apices with wide periapical lesions without surgery. Previously, the predictability of these parameters with non-surgical procedures was uncertain, but now, with the use of a dental operating microscope, it has become more predictable. Another reason could be that extra visits are no longer required due to major advances in the armamentarium and materials used for apexification.</p>","PeriodicalId":94271,"journal":{"name":"World journal of methodology","volume":"15 1","pages":"96923"},"PeriodicalIF":0.0,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11525894/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143672191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Getting physical with medical education: Exercise based virtual anatomy review classes for medical students.","authors":"Nadeesha R Samarasinghe, Taniya S Nagpal, Michele L Barbeau, Charys M Martin","doi":"10.5662/wjm.v15.i1.95985","DOIUrl":"10.5662/wjm.v15.i1.95985","url":null,"abstract":"<p><p>The benefits of regular physical activity are well known. Yet, few studies have examined the effectiveness of integrating physical activity (PA) into curricula within a post-secondary setting. To investigate the incorporation of PA into medical curriculum, we developed a series of optional exercise-based review sessions designed to reinforce musculoskeletal (MSK) anatomy course material. These synchronous sessions were co-taught by a group fitness instructor and an anatomy instructor. The fitness instructor would lead students through both strength and yoga style exercises, while the anatomy instructor asked questions about relevant anatomical structures related to course material previously covered. After the sessions, participants were asked to evaluate the classes on their self-reported exam preparedness in improving MSK anatomy knowledge, PA levels, and mental wellbeing. Thirty participants completed surveys; a majority agreed that the classes increased understanding of MSK concepts (90.0%) and activity levels (97.7%). Many (70.0%) felt that the classes helped reduce stress. The majority of respondents (90.0%) agreed that the classes contributed to increased feelings of social connectedness. Overall, medical students saw benefit in PA based interventions to supplement MSK course concepts. Along with increasing activity levels and promoting health behaviours, integrating PA into medical curriculum may improve comprehension of learning material, alleviate stress and foster social connectivity among medical students.</p>","PeriodicalId":94271,"journal":{"name":"World journal of methodology","volume":"15 1","pages":"95985"},"PeriodicalIF":0.0,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11525886/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143672084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reevaluating health metrics: Unraveling the limitations of disability-adjusted life years as an indicator in disease burden assessment.","authors":"Ariel Beresniak, Dominique Bremond-Gignac, Danielle Dupont, Gerard Duru","doi":"10.5662/wjm.v15.i1.95796","DOIUrl":"10.5662/wjm.v15.i1.95796","url":null,"abstract":"<p><p>In 1993, the World Bank released a global report on the efficacy of health promotion, introducing the disability-adjusted life years (DALY) as a novel indicator. The DALY, a composite metric incorporating temporal and qualitative data, is grounded in preferences regarding disability status. This review delineates the algorithm used to calculate the value of the proposed DALY synthetic indicator and elucidates key methodological challenges associated with its application. In contrast to the quality-adjusted life years approach, derived from multi-attribute utility theory, the DALY stands as an independent synthetic indicator that adopts the assumptions of the Time Trade Off utility technique to define Disability Weights. Claiming to rely on no mathematical or economic theory, DALY users appear to have exempted themselves from verifying whether this indicator meets the classical properties required of all indicators, notably content validity, reliability, specificity, and sensitivity. The DALY concept emerged primarily to facilitate comparisons of the health impacts of various diseases globally within the framework of the Global Burden of Disease initiative, leading to numerous publications in international literature. Despite widespread adoption, the DALY synthetic indicator has prompted significant methodological concerns since its inception, manifesting in inconsistent and non-reproducible results. Given the substantial diffusion of the DALY indicator and its critical role in health impact assessments, a reassessment is warranted. This reconsideration is imperative for enhancing the robustness and reliability of public health decision-making processes.</p>","PeriodicalId":94271,"journal":{"name":"World journal of methodology","volume":"15 1","pages":"95796"},"PeriodicalIF":0.0,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11525889/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143672193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advances in the treatment of autism spectrum disorder: Wharton jelly mesenchymal stem cell transplantation.","authors":"Serdar Kabatas, Erdinç Civelek, Eyüp Can Savrunlu, Umut Karaaslan, Özlem Yıldız, Erdal Karaöz","doi":"10.5662/wjm.v15.i1.95857","DOIUrl":"10.5662/wjm.v15.i1.95857","url":null,"abstract":"<p><strong>Background: </strong>Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder with multifaceted origins. In recent studies, neuroinflammation and immune dysregulation have come to the forefront in its pathogenesis. There are studies suggesting that stem cell therapy may be effective in the treatment of ASD.</p><p><strong>Aim: </strong>To evolve the landscape of ASD treatment, focusing on the potential benefits and safety of stem cell transplantation.</p><p><strong>Methods: </strong>A detailed case report is presented, displaying the positive outcomes observed in a child who underwent intrathecal and intravenous Wharton's jelly-derived mesenchymal stem cells (WJ-MSCs) transplantation combined with neurorehabilitation.</p><p><strong>Results: </strong>The study demonstrates a significant improvement in the child's functional outcomes (Childhood Autism Rating Scale, Denver 2 Developmental Screening Test), especially in language and gross motor skills. No serious side effects were encountered during the 2-year follow-up.</p><p><strong>Conclusion: </strong>The findings support the safety and effectiveness of WJ-MSC transplantation in managing ASD.</p>","PeriodicalId":94271,"journal":{"name":"World journal of methodology","volume":"15 1","pages":"95857"},"PeriodicalIF":0.0,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11525897/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143672161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}