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Sarcoidosis Masquerading as Breast Implant- Associated Anaplastic Large Cell Lymphoma -  The Importance of Definitive Pathology to Guide Therapy. 结节病伪装成乳房假体相关间变性大细胞淋巴瘤-明确病理指导治疗的重要性。
WMJ : official publication of the State Medical Society of Wisconsin Pub Date : 2025-01-01
Riley Young, Emelyn Zaworski, Melissa Hart, Bradley Grewe, Ellen Liang, Yvonne Pierpont
{"title":"Sarcoidosis Masquerading as Breast Implant- Associated Anaplastic Large Cell Lymphoma -  The Importance of Definitive Pathology to Guide Therapy.","authors":"Riley Young, Emelyn Zaworski, Melissa Hart, Bradley Grewe, Ellen Liang, Yvonne Pierpont","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is a rare critical outcome of breast implantation that typically presents 8 to 10 years after textured-implant placement with periprosthetic seroma. Treatment consists of implant removal and capsulectomy, which is typically curative. But in rare case, malignant infiltration through the capsule results in disseminated disease, necessitating aggressive treatment with systemic chemotherapy. Sarcoidosis, a chronic systemic granulomatous disease characterized by noncaseating granulomas, is another rare cause of periprosthetic seroma.</p><p><strong>Case presentation: </strong>A 61-year-old female with a history of invasive ductal carcinoma of the breast status post textured implant-based reconstruction presented with late periprosthetic seroma and overlying rash. Cytology of seroma aspirate was suggestive of BIA-ALCL, and positron emission tomography-computed tomography was concerning for invasive disease. Surgical specimen pathology of the implant-capsule complex and skin punch biopsy of the overlying rash revealed only granulomatous inflammation. The patient was diagnosed with sarcoidosis and spared systemic chemotherapy treatment for disseminated BIA-ALCL.</p><p><strong>Conclusions: </strong>BIA-ALCL should be ruled out in all cases of late periprosthetic seroma. Definitive surgical pathology is necessary to prevent misdiagnosis and inappropriate treatment of masquerading entities, such as sarcoidosis.</p>","PeriodicalId":94268,"journal":{"name":"WMJ : official publication of the State Medical Society of Wisconsin","volume":"124 1","pages":"71-73"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144059598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comment on 'Enhancing Diagnosis of Obstructive Lung Diseases: Insights From Clinical Characteristics in a Prospective Cohort Study'. “增强阻塞性肺疾病的诊断：来自前瞻性队列研究临床特征的见解”
WMJ : official publication of the State Medical Society of Wisconsin Pub Date : 2025-01-01
Rachana Mehta, Ranjana Sah, Shubham Kumar
{"title":"Comment on 'Enhancing Diagnosis of Obstructive Lung Diseases: Insights From Clinical Characteristics in a Prospective Cohort Study'.","authors":"Rachana Mehta, Ranjana Sah, Shubham Kumar","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":94268,"journal":{"name":"WMJ : official publication of the State Medical Society of Wisconsin","volume":"124 1","pages":"4"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144060909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Statistical Thinking Part 4: Probability, Statistics, and the Central Limit Theorem. 统计思维第4部分：概率、统计和中心极限定理。
WMJ : official publication of the State Medical Society of Wisconsin Pub Date : 2025-01-01
Robert A Calder, Jayshil J Patel
{"title":"Statistical Thinking Part 4: Probability, Statistics, and the Central Limit Theorem.","authors":"Robert A Calder, Jayshil J Patel","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":94268,"journal":{"name":"WMJ : official publication of the State Medical Society of Wisconsin","volume":"124 1","pages":"74-77"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144058477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Periorbital Dermatitis Induced by Apixaban. 阿哌沙班致眼眶周围皮炎。
WMJ : official publication of the State Medical Society of Wisconsin Pub Date : 2025-01-01
Kelsey Koenig, Grace Tews, Aleksander Downs
{"title":"Periorbital Dermatitis Induced by Apixaban.","authors":"Kelsey Koenig, Grace Tews, Aleksander Downs","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Periorbital dermatitis can be due rarely to an adverse drug reaction. We present a case of a patient whose periorbital dermatitis was caused by apixaban.</p><p><strong>Case presentation: </strong>A 76-year-old female presented with severe periorbital dermatitis 3 weeks after starting apixaban. Varying potencies of antihistamines, topical steroids, calcineurin inhibitors, and emollients were used over a 20-month span with no relief of symptoms. Upon discontinuing apixaban and switching to rivaroxaban, she experienced complete resolution of her symptoms.</p><p><strong>Discussion: </strong>Periorbital dermatitis is a lesser-known adverse effect of apixaban. To our knowledge, there has only been 1 other reported case of periorbital dermatitis induced by apixaban.</p><p><strong>Conclusions: </strong>We report this case to increase awareness among clinicians of adverse effects of apixaban and to encourage consideration of drug side effects as part of the differential diagnosis for new skin complaints.</p>","PeriodicalId":94268,"journal":{"name":"WMJ : official publication of the State Medical Society of Wisconsin","volume":"124 1","pages":"67-68"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144045647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
High-Value Imaging in an Era of Uncertainty, Growth, and Disruptive Technologies. 不确定、增长和颠覆性技术时代的高价值成像。
WMJ : official publication of the State Medical Society of Wisconsin Pub Date : 2025-01-01
Scott B Reeder, Robert N Golden
{"title":"High-Value Imaging in an Era of Uncertainty, Growth, and Disruptive Technologies.","authors":"Scott B Reeder, Robert N Golden","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":94268,"journal":{"name":"WMJ : official publication of the State Medical Society of Wisconsin","volume":"124 1","pages":"78-79"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144016119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Babesiosis - An Unseen Epidemic. 巴贝斯虫病——一种看不见的流行病。
WMJ : official publication of the State Medical Society of Wisconsin Pub Date : 2025-01-01
Noor Fatima, Steven Lippmann
{"title":"Babesiosis - An Unseen Epidemic.","authors":"Noor Fatima, Steven Lippmann","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":94268,"journal":{"name":"WMJ : official publication of the State Medical Society of Wisconsin","volume":"124 1","pages":"3-4"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144035402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Shifting From 'Patient-Centered' to 'Patient-Wanted' Approach. 从“以病人为中心”转向“病人需要”。
WMJ : official publication of the State Medical Society of Wisconsin Pub Date : 2025-01-01
Gagandeep Singh
{"title":"Shifting From 'Patient-Centered' to 'Patient-Wanted' Approach.","authors":"Gagandeep Singh","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":94268,"journal":{"name":"WMJ : official publication of the State Medical Society of Wisconsin","volume":"124 1","pages":"5"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144058492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cobenfy (xanomeline-trospium). Cobenfy (xanomeline-trospium) .
WMJ : official publication of the State Medical Society of Wisconsin Pub Date : 2025-01-01
Brandon Johnson, Abir T El-Alfy, Kristin Busse
{"title":"Cobenfy (xanomeline-trospium).","authors":"Brandon Johnson, Abir T El-Alfy, Kristin Busse","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":94268,"journal":{"name":"WMJ : official publication of the State Medical Society of Wisconsin","volume":"124 ","pages":"P1-P2"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144039582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fibrocartilaginous Embolism Spinal Cord Infarction, Mistaken for Glial Fibrillary Acidic Protein Autoimmune Transverse Myelitis: A Case Report. 纤维软骨栓塞性脊髓梗死，误诊为胶质纤维酸性蛋白自身免疫性横脊髓炎1例
WMJ : official publication of the State Medical Society of Wisconsin Pub Date : 2025-01-01
Felix E Chukwudelunzu, Timothy Young
{"title":"Fibrocartilaginous Embolism Spinal Cord Infarction, Mistaken for Glial Fibrillary Acidic Protein Autoimmune Transverse Myelitis: A Case Report.","authors":"Felix E Chukwudelunzu, Timothy Young","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Fibrocartilaginous embolism causing spinal cord infarct is rare, and a high index of clinical suspicion is needed for accurate diagnosis.</p><p><strong>Case presentation: </strong>A 65-year-old woman presented to our hospital with back pain, paraparesis, and neurogenic bladder. Magnetic resonance imaging showed a T4-T7 signal abnormality that was misdiagnosed initially and treated as autoimmune myelitis.</p><p><strong>Discussion: </strong>Fibrocartilaginous spinal cord infarction is rare and remains a clinical diagnosis with supportive imaging findings. The imaging findings may be nonspecific, and other etiologic diagnostic considerations must be excluded.</p><p><strong>Conclusion: </strong>Fibrocartilaginous embolism causing spinal cord infarct can be mistaken for transverse myelitis. A high index of clinical suspicion with clinical and radiologic correlation is necessary to make accurate diagnosis and avoid unnecessary treatment.</p>","PeriodicalId":94268,"journal":{"name":"WMJ : official publication of the State Medical Society of Wisconsin","volume":"124 1","pages":"63-66"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144034258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of LGBTQ+ Health Education in the Preclinical Curriculum at a Public Midwest Medical School. 中西部某公立医学院临床基础课程中LGBTQ+健康教育的评价
WMJ : official publication of the State Medical Society of Wisconsin Pub Date : 2025-01-01
Tess I Jewell, Elizabeth M Petty
{"title":"Evaluation of LGBTQ+ Health Education in the Preclinical Curriculum at a Public Midwest Medical School.","authors":"Tess I Jewell, Elizabeth M Petty","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>People who identify as lesbian, gay, bisexual, transgender, and queer/questioning (LGBTQ+) face health disparities and negative health care experiences. Medical student education may be leveraged as a strategy to improve care for these patients; however, studies suggest gaps in current LGBTQ+ health education.</p><p><strong>Objective: </strong>This project sought to evaluate how LGBTQ+ health is taught in the preclinical curriculum at a Midwest medical school.</p><p><strong>Methods: </strong>The institution's curriculum repository was searched systematically for materials that included information on LGBTQ+ health used in preclinical courses in the 2021-2022 academic year. Information was compiled based on previously utilized evaluation tools and additional measurements developed by the authors to provide further clarity.</p><p><strong>Results: </strong>Seventy items were identified in the curriculum repository; 38 (54%) were required for students to review. Commonly addressed topics include communication skills, terminology, and variations in sex characteristics. Topic gaps identified include mental health, cancer screening, and gender-affirming care. Among the 33 clinical skills sessions in the preclinical curriculum, 5 standardized patient cases included LGBTQ+ patient representation.</p><p><strong>Conclusions: </strong>There was variability in coverage of LGBTQ+ health topics, with particularly more on language and variations in sex characteristics and less on mental health, cancer screening, and gender-affirming care. This study identifies opportunities to improve LGBTQ+ health education and demonstrates a framework that may be applied to evaluate curricula in other programs, to ideally enhance coverage of this material and, ultimately, improve care of LGBTQ+ patients.</p>","PeriodicalId":94268,"journal":{"name":"WMJ : official publication of the State Medical Society of Wisconsin","volume":"124 1","pages":"35-41"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144059597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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