Anna R Yousaf, Margaret M Cortese, Allan W Taylor, Karen R Broder, Matthew E Oster, Joshua M Wong, Alice Y Guh, David W McCormick, Satoshi Kamidani, Elizabeth P Schlaudecker, Kathryn M Edwards, C Buddy Creech, Mary A Staat, Ermias D Belay, Paige Marquez, John R Su, Mark B Salzman, Deborah Thompson, Angela P Campbell
{"title":"Reported cases of multisystem inflammatory syndrome in children aged 12-20 years in the USA who received a COVID-19 vaccine, December, 2020, through August, 2021: a surveillance investigation.","authors":"Anna R Yousaf, Margaret M Cortese, Allan W Taylor, Karen R Broder, Matthew E Oster, Joshua M Wong, Alice Y Guh, David W McCormick, Satoshi Kamidani, Elizabeth P Schlaudecker, Kathryn M Edwards, C Buddy Creech, Mary A Staat, Ermias D Belay, Paige Marquez, John R Su, Mark B Salzman, Deborah Thompson, Angela P Campbell","doi":"10.1016/S2352-4642(22)00028-1","DOIUrl":"10.1016/S2352-4642(22)00028-1","url":null,"abstract":"<p><strong>Background: </strong>Multisystem inflammatory syndrome in children (MIS-C) is a hyperinflammatory condition associated with antecedent SARS-CoV-2 infection. In the USA, reporting of MIS-C after vaccination is required under COVID-19 vaccine emergency use authorisations. We aimed to investigate reports of individuals aged 12-20 years with MIS-C after COVID-19 vaccination reported to passive surveillance systems or through clinician outreach to the US Centers for Disease Control and Prevention (CDC).</p><p><strong>Methods: </strong>In this surveillance activity, we investigated potential cases of MIS-C after COVID-19 vaccination reported to CDC's MIS-C national surveillance system, the Vaccine Adverse Event Reporting System (co-administered by CDC and the US Food and Drug Administration), and CDC's Clinical Immunization Safety Assessment Project. A multidisciplinary team adjudicated cases by use of the CDC MIS-C definition. Any positive SARS-CoV-2 serology test satisfied case criteria; although anti-nucleocapsid antibodies indicate previous SARS-CoV-2 infection, anti-spike protein antibodies indicate either past or recent infection or COVID-19 vaccination. We describe the demographic and clinical features of cases, stratified by laboratory evidence of SARS-CoV-2 infection. To calculate the reporting rate of MIS-C, we divided the count of all individuals meeting the MIS-C case definition, and of those without evidence of SARS-CoV-2 infection, by the number of individuals aged 12-20 years in the USA who received one or more COVID-19 vaccine doses up to Aug 31, 2021, obtained from CDC national vaccine surveillance data.</p><p><strong>Findings: </strong>Using surveillance results from Dec 14, 2020, to Aug 31, 2021, we identified 21 individuals with MIS-C after COVID-19 vaccination. Of these 21 individuals, median age was 16 years (range 12-20); 13 (62%) were male and eight (38%) were female. All 21 were hospitalised: 12 (57%) were admitted to an intensive care unit and all were discharged home. 15 (71%) of 21 individuals had laboratory evidence of past or recent SARS-CoV-2 infection, and six (29%) did not. As of Aug 31, 2021, 21 335 331 individuals aged 12-20 years had received one or more doses of a COVID-19 vaccine, making the overall reporting rate for MIS-C after vaccination 1·0 case per million individuals receiving one or more doses in this age group. The reporting rate in only those without evidence of SARS-CoV-2 infection was 0·3 cases per million vaccinated individuals.</p><p><strong>Interpretation: </strong>Here, we describe a small number of individuals with MIS-C who had received one or more doses of a COVID-19 vaccine before illness onset; the contribution of vaccination to these illnesses is unknown. Our findings suggest that MIS-C after COVID-19 vaccination is rare. Continued reporting of potential cases and surveillance for MIS-C illnesses after COVID-19 vaccination is warranted.</p><p><strong>Funding: </strong>US Centers for","PeriodicalId":94246,"journal":{"name":"The Lancet. Child & adolescent health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864018/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90766119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mitchell T G Pratt, Tasnim Abdalla, P. Richmond, H. Moore, T. Snelling, Christopher C Blyth, M. Bhuiyan
{"title":"Prevalence of respiratory viruses in community-acquired pneumonia in children: a systematic review and meta-analysis.","authors":"Mitchell T G Pratt, Tasnim Abdalla, P. Richmond, H. Moore, T. Snelling, Christopher C Blyth, M. Bhuiyan","doi":"10.1016/s2352-4642(22)00092-x","DOIUrl":"https://doi.org/10.1016/s2352-4642(22)00092-x","url":null,"abstract":"","PeriodicalId":94246,"journal":{"name":"The Lancet. Child & adolescent health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88007467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Ssenyonga, C. Stiller, K. Nakata, J. Shalkow, Sheilagh Redmond, J. Bulliard, F. Girardi, C. Fowler, Raphael Marcos-Gragera, A. Bonaventure, N. Saint-Jacques, P. Minicozzi, P. De, M. Rodríguez-Barranco, S. Larønningen, V. Di Carlo, M. Mägi, M. Valkov, K. Seppä, D. Wyn Huws, M. Coleman, C. Allemani, S. Bouzbid, M. Hamdi-Chérif, L. Kara, K. Meguenni, D. Regagba, S. Bayo, T. Cheick Bougadari, S. Manraj, K. Bendahhou, A. Ladipo, O. Ogunbiyi, N. Somdyala, M. Chaplin, F. Moreno, Gladis Calabrano, Silvia Espinola, B. Carballo Quintero, R. Fita, Walter Laspada, Susana Ibáñez, C. Lima, A. Mafra da Costa, P. C. D. de Souza, Juliana Chaves, C. Laporte, M. Curado, J. D. de Oliveira, C. Veneziano, D. Veneziano, A. Almeida, Maria Latorre, G. Azevedo e Silva, M. Rebelo, Marceli de Oliveira Santos, J. Galaz, M. Aparicio Aravena, J. Sanhueza Monsalve, D. Herrmann, Solange P. Vargas, V. Herrera, C. Uribe, L. Bravo, L. García, N. Arias-Ortiz, Daniela Morantes, D. Jurado, M. Y. Yépez Chamorro, Sandra Delgado, Melissa Ramir
{"title":"Worldwide trends in population-based survival for children, adolescents, and young adults diagnosed with leukaemia, by subtype, during 2000-14 (CONCORD-3): analysis of individual data from 258 cancer registries in 61 countries.","authors":"N. Ssenyonga, C. Stiller, K. Nakata, J. Shalkow, Sheilagh Redmond, J. Bulliard, F. Girardi, C. Fowler, Raphael Marcos-Gragera, A. Bonaventure, N. Saint-Jacques, P. Minicozzi, P. De, M. Rodríguez-Barranco, S. Larønningen, V. Di Carlo, M. Mägi, M. Valkov, K. Seppä, D. Wyn Huws, M. Coleman, C. Allemani, S. Bouzbid, M. Hamdi-Chérif, L. Kara, K. Meguenni, D. Regagba, S. Bayo, T. Cheick Bougadari, S. Manraj, K. Bendahhou, A. Ladipo, O. Ogunbiyi, N. Somdyala, M. Chaplin, F. Moreno, Gladis Calabrano, Silvia Espinola, B. Carballo Quintero, R. Fita, Walter Laspada, Susana Ibáñez, C. Lima, A. Mafra da Costa, P. C. D. de Souza, Juliana Chaves, C. Laporte, M. Curado, J. D. de Oliveira, C. Veneziano, D. Veneziano, A. Almeida, Maria Latorre, G. Azevedo e Silva, M. Rebelo, Marceli de Oliveira Santos, J. Galaz, M. Aparicio Aravena, J. Sanhueza Monsalve, D. Herrmann, Solange P. Vargas, V. Herrera, C. Uribe, L. Bravo, L. García, N. Arias-Ortiz, Daniela Morantes, D. Jurado, M. Y. Yépez Chamorro, Sandra Delgado, Melissa Ramir","doi":"10.1016/S2352-4642(22)00095-5","DOIUrl":"https://doi.org/10.1016/S2352-4642(22)00095-5","url":null,"abstract":"","PeriodicalId":94246,"journal":{"name":"The Lancet. Child & adolescent health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72854351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hair care: a lesson in trauma-informed medical practice.","authors":"Dhanya Kumar, Heather C Forkey","doi":"10.1016/s2352-4642(22)00069-4","DOIUrl":"https://doi.org/10.1016/s2352-4642(22)00069-4","url":null,"abstract":"","PeriodicalId":94246,"journal":{"name":"The Lancet. Child & adolescent health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74816403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correction to Lancet Child Adolesc Health 2022; published online March 28. https://doi.org/10.1016/S2352-4642(22)00059-1","authors":"","doi":"10.1016/s2352-4642(22)00126-2","DOIUrl":"https://doi.org/10.1016/s2352-4642(22)00126-2","url":null,"abstract":"","PeriodicalId":94246,"journal":{"name":"The Lancet. Child & adolescent health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80611995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V. Totsika, Ashley Liew, M. Absoud, C. Adnams, E. Emerson
{"title":"Mental health problems in children with intellectual disability.","authors":"V. Totsika, Ashley Liew, M. Absoud, C. Adnams, E. Emerson","doi":"10.1016/s2352-4642(22)00067-0","DOIUrl":"https://doi.org/10.1016/s2352-4642(22)00067-0","url":null,"abstract":"","PeriodicalId":94246,"journal":{"name":"The Lancet. Child & adolescent health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87048949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Massimino, G. Casiraghi, M. Armiraglio, Daniele Cabibbe, R. Luksch, M. Terenziani, M. Casanova, F. Spreafico, C. Meazza, M. Podda, V. Biassoni, E. Schiavello, S. Chiaravalli, N. Puma, L. Bergamaschi, G. Gattuso, G. Sironi, O. Nigro, V. Livellara, Shushan Hovsepyan, A. Ferrari, C. Clerici
{"title":"Caring for children with cancer evacuated from Ukraine.","authors":"M. Massimino, G. Casiraghi, M. Armiraglio, Daniele Cabibbe, R. Luksch, M. Terenziani, M. Casanova, F. Spreafico, C. Meazza, M. Podda, V. Biassoni, E. Schiavello, S. Chiaravalli, N. Puma, L. Bergamaschi, G. Gattuso, G. Sironi, O. Nigro, V. Livellara, Shushan Hovsepyan, A. Ferrari, C. Clerici","doi":"10.1016/s2352-4642(22)00125-0","DOIUrl":"https://doi.org/10.1016/s2352-4642(22)00125-0","url":null,"abstract":"","PeriodicalId":94246,"journal":{"name":"The Lancet. Child & adolescent health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88659154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Radhika Valanju, Meera Barani, Dominik Mautner, Imeelya Al Hadaya, A. Cross, Melani Gunawardana, Ava Lambie, Emily McMahon, Arnav Narula, Bowen Ren, Dominique R, Aviral Sharda, Alexander Sinnett, Azman Tanvir, Henrik Tran, Fulin Yan, M. Mandoh, Hoi Lun Cheng, S. Mihrshahi, P. Phongsavan, J. Redfern, R. Raeside, S. Partridge
{"title":"Youth perspective on chronic disease prevention","authors":"Radhika Valanju, Meera Barani, Dominik Mautner, Imeelya Al Hadaya, A. Cross, Melani Gunawardana, Ava Lambie, Emily McMahon, Arnav Narula, Bowen Ren, Dominique R, Aviral Sharda, Alexander Sinnett, Azman Tanvir, Henrik Tran, Fulin Yan, M. Mandoh, Hoi Lun Cheng, S. Mihrshahi, P. Phongsavan, J. Redfern, R. Raeside, S. Partridge","doi":"10.1016/S2352-4642(22)00131-6","DOIUrl":"https://doi.org/10.1016/S2352-4642(22)00131-6","url":null,"abstract":"","PeriodicalId":94246,"journal":{"name":"The Lancet. Child & adolescent health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82699486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An open letter on the war in Ukraine from UK paediatric emergency doctors.","authors":"D. Magnus, P. Reavley, James Denselow","doi":"10.1016/s2352-4642(22)00099-2","DOIUrl":"https://doi.org/10.1016/s2352-4642(22)00099-2","url":null,"abstract":"","PeriodicalId":94246,"journal":{"name":"The Lancet. Child & adolescent health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72990241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}