Faraz Alizadeh MD, Kimberlee Gauvreau ScD, Jessica A Barreto MD, Matt Hall PhD, Emily Bucholz MD PhD, Meena Nathan MD, Prof Jane W Newburger MD, Sally Vitali MD, Prof Ravi R Thiagarajan MBBS, Titus Chan MD, Katie M Moynihan MBBS
{"title":"Paediatric extracorporeal membrane oxygenation use by social determinants: a multicentre retrospective cohort study","authors":"Faraz Alizadeh MD, Kimberlee Gauvreau ScD, Jessica A Barreto MD, Matt Hall PhD, Emily Bucholz MD PhD, Meena Nathan MD, Prof Jane W Newburger MD, Sally Vitali MD, Prof Ravi R Thiagarajan MBBS, Titus Chan MD, Katie M Moynihan MBBS","doi":"10.1016/s2352-4642(25)00134-8","DOIUrl":"https://doi.org/10.1016/s2352-4642(25)00134-8","url":null,"abstract":"Social determinants of health have upstream effects on health-care access and decision making to influence outcomes. We aimed to study the use of extracorporeal membrane oxygenation (ECMO) in children according to social determinants of health.","PeriodicalId":94246,"journal":{"name":"The Lancet. Child & adolescent health","volume":"93 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144503989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Which children in the USA have access to heroic salvage therapy?","authors":"Garrett Keim, Nadir Yehya","doi":"10.1016/s2352-4642(25)00166-x","DOIUrl":"https://doi.org/10.1016/s2352-4642(25)00166-x","url":null,"abstract":"","PeriodicalId":94246,"journal":{"name":"The Lancet. Child & adolescent health","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144503771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Celeste Cleveland MD, Ambinintsoa H Ralaidovy PhD, Chrys Jallo RPh, Felicia Frank BS, Taghreed Adam MD PhD, Andre Ilbawi MD, Prof Jessica Boklan MD MPH
{"title":"The global landscape and development pipeline for childhood cancer medicines: a comprehensive analysis with dashboard generation","authors":"Celeste Cleveland MD, Ambinintsoa H Ralaidovy PhD, Chrys Jallo RPh, Felicia Frank BS, Taghreed Adam MD PhD, Andre Ilbawi MD, Prof Jessica Boklan MD MPH","doi":"10.1016/s2352-4642(25)00142-7","DOIUrl":"https://doi.org/10.1016/s2352-4642(25)00142-7","url":null,"abstract":"Although childhood cancer survival outcomes have markedly improved over the past several decades due to therapeutic advancements, significant gaps remain in accessibility to cancer medicines for children. We aimed to analyse the global paediatric oncology landscape and pipeline of all childhood cancer medicines that are in common use or development.","PeriodicalId":94246,"journal":{"name":"The Lancet. Child & adolescent health","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144503994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Msandeni Chiume, Joy E Lawn, Nahya Salim, William Macharia, Maria Oden, Chinyere Ezeaka, Kara M Palamountain, Abiy Seifu Estifanos, Rebecca Richards-Kortum
{"title":"Neonatology's future: securing most impact where most newborn infants die","authors":"Msandeni Chiume, Joy E Lawn, Nahya Salim, William Macharia, Maria Oden, Chinyere Ezeaka, Kara M Palamountain, Abiy Seifu Estifanos, Rebecca Richards-Kortum","doi":"10.1016/s2352-4642(25)00184-1","DOIUrl":"https://doi.org/10.1016/s2352-4642(25)00184-1","url":null,"abstract":"","PeriodicalId":94246,"journal":{"name":"The Lancet. Child & adolescent health","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144503999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Prof Daniele De Luca PhD, Prof Neena Modi FMedSci, Prof Peter Davis MD, Prof Satoshi Kusuda PhD, Prof Saskia N de Wildt PhD, Prof Martin Keszler MD, Allyah Abbas-Hanif MD, Prof Sandra E Juul PhD, Prof Mark Turner PhD, Prof J Jane Pillow PhD, Prof Nikki Robertson PhD, Prof Manuel Sanchez-Luna PhD, Prof David G Tingay PhD, Prof Alexandra Benachi PhD, Flavia Bustreo MD, Gianluca Ianiro MD, Prof Mark Hanson PhD, Prof Jan Deprest PhD, Prof Paolo De Coppi PhD, Agnes van den Hoogen PhD, Prof William Tarnow-Mordi PhD, Anna Zanin MD, Ju-Lee Oei MD, Huayan Zhang MD, Prof Victor Javier Lara-Diaz PhD, Lloyd Tooke MD, Prof Heidi Flori MD, Prof Walter Ricciardi PhD, Prof Steven H Abman MD
{"title":"The Lancet Child & Adolescent Health Commission on the future of neonatology","authors":"Prof Daniele De Luca PhD, Prof Neena Modi FMedSci, Prof Peter Davis MD, Prof Satoshi Kusuda PhD, Prof Saskia N de Wildt PhD, Prof Martin Keszler MD, Allyah Abbas-Hanif MD, Prof Sandra E Juul PhD, Prof Mark Turner PhD, Prof J Jane Pillow PhD, Prof Nikki Robertson PhD, Prof Manuel Sanchez-Luna PhD, Prof David G Tingay PhD, Prof Alexandra Benachi PhD, Flavia Bustreo MD, Gianluca Ianiro MD, Prof Mark Hanson PhD, Prof Jan Deprest PhD, Prof Paolo De Coppi PhD, Agnes van den Hoogen PhD, Prof William Tarnow-Mordi PhD, Anna Zanin MD, Ju-Lee Oei MD, Huayan Zhang MD, Prof Victor Javier Lara-Diaz PhD, Lloyd Tooke MD, Prof Heidi Flori MD, Prof Walter Ricciardi PhD, Prof Steven H Abman MD","doi":"10.1016/s2352-4642(25)00106-3","DOIUrl":"https://doi.org/10.1016/s2352-4642(25)00106-3","url":null,"abstract":"Neonatal mortality remains unacceptably high throughout the world. Survival of sick infants in their first month of life has improved over the past six decades. However, many comorbidities persist, with lifelong implications for health. The current ecosystem for research and development of drugs and medical devices to treat neonatal disorders is hindering further improvements to neonatal outcomes, especially infants born preterm or needing critical care. Innovation is lagging, and this is a public health problem characterised by multifactorial challenges in leadership, collaboration, regulation, funding, and commercial viability. The <ce:italic>Lancet Child & Adolescent Health</ce:italic> Commission on the future of neonatology was created to consider these challenges and design a roadmap of strategies to accelerate research and development that will innovate and improve health care for neonates. We call for regulatory agencies, governments, funders, industry partners, and clinical researchers from diverse medical fields to invest in effective pathways for drug and medical device development and to unite in responsive and dynamic collaborations with diverse patients, families, and advocacy groups whose engagement in clinical research and advocacy can help neonatologists to achieve the best science and health equity for neonates worldwide, now and in the future.","PeriodicalId":94246,"journal":{"name":"The Lancet. Child & adolescent health","volume":"78 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144503995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Junayd Hussain MSc, Kalina Georgieva BHK, Cal H Robinson MD, Nivethika Jeyakumar MSc, Graham Smith PhD, Prof Tammy Brady MD PhD, Allison Dart MD MSc, Janis Dionne MD, Sabine Karam MD, Ashlene M McKay MD, Prof Rulan Parekh MD MSc, Rukshana Shroff MD PhD, Prof Manish D Sinha MBBS PhD, Andrew M South MD MSc, Carol Vincent MD MSc, Prof Manish M Sood MD MSc, Rahul Chanchlani MD MSc
{"title":"Long-term kidney outcomes in children and adolescents with hypertension: a propensity-matched cohort study","authors":"Junayd Hussain MSc, Kalina Georgieva BHK, Cal H Robinson MD, Nivethika Jeyakumar MSc, Graham Smith PhD, Prof Tammy Brady MD PhD, Allison Dart MD MSc, Janis Dionne MD, Sabine Karam MD, Ashlene M McKay MD, Prof Rulan Parekh MD MSc, Rukshana Shroff MD PhD, Prof Manish D Sinha MBBS PhD, Andrew M South MD MSc, Carol Vincent MD MSc, Prof Manish M Sood MD MSc, Rahul Chanchlani MD MSc","doi":"10.1016/s2352-4642(25)00127-0","DOIUrl":"https://doi.org/10.1016/s2352-4642(25)00127-0","url":null,"abstract":"Hypertension affects 6% of all children and adolescents, is increasing in prevalence, and is associated with adverse cardiovascular outcomes. In childhood chronic kidney disease, hypertension is associated with progression to kidney failure. However, direct evidence linking childhood hypertension with long-term adverse kidney outcomes is scarce. We aimed to determine the long-term risk of major adverse kidney events (MAKEs) among children and adolescents diagnosed with hypertension.","PeriodicalId":94246,"journal":{"name":"The Lancet. Child & adolescent health","volume":"645 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144503996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xinli Song PhD, Bin Zhou PhD, Prof Sarah Baird PhD, Prof Chunling Lu PhD, Zhiying Song PhD, Yi Zhang PhD, Ruolin Wang PhD, Jianuo Jiang MS PhD, Li Chen PhD, Jieyu Liu PhD, Wen Yuan PhD, Yunfei Liu PhD, Jiajia Dang PhD, Peijin Hu PhD, Prof Jun Ma PhD, Prof Yanhui Dong PhD, Prof Yi Song PhD, Majid Ezzati FMedSci, Prof Susan M Sawyer MD
{"title":"Trends and predictions to 2030 in demographic structures and metabolic health for children and adolescents in China: analysis of national school health surveys from 2000 to 2019","authors":"Xinli Song PhD, Bin Zhou PhD, Prof Sarah Baird PhD, Prof Chunling Lu PhD, Zhiying Song PhD, Yi Zhang PhD, Ruolin Wang PhD, Jianuo Jiang MS PhD, Li Chen PhD, Jieyu Liu PhD, Wen Yuan PhD, Yunfei Liu PhD, Jiajia Dang PhD, Peijin Hu PhD, Prof Jun Ma PhD, Prof Yanhui Dong PhD, Prof Yi Song PhD, Majid Ezzati FMedSci, Prof Susan M Sawyer MD","doi":"10.1016/s2352-4642(25)00140-3","DOIUrl":"https://doi.org/10.1016/s2352-4642(25)00140-3","url":null,"abstract":"Understanding the changing metabolic health burden among children and adolescents is crucial for current and future public health resource allocation in China, particularly given rapid population ageing. We aimed to estimate trends in the metabolic burden in children and adolescents aged 7–18 years from 2000 to 2030, using overweight, obesity, and hypertension as proxy indicators.","PeriodicalId":94246,"journal":{"name":"The Lancet. Child & adolescent health","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144335591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}