The Lancet. Child & adolescent health最新文献

{"title":"Sonia Livingstone: getting children's digital rights right.","authors":"Heather Van Epps","doi":"10.1016/S2352-4642(26)00281-6","DOIUrl":"https://doi.org/10.1016/S2352-4642(26)00281-6","url":null,"abstract":"","PeriodicalId":94246,"journal":{"name":"The Lancet. Child & adolescent health","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149248320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mental health, ADHD, and autism: two reports, one call to act.","authors":"Naomi Wilson, Helen Minnis","doi":"10.1016/S2352-4642(26)00278-6","DOIUrl":"https://doi.org/10.1016/S2352-4642(26)00278-6","url":null,"abstract":"","PeriodicalId":94246,"journal":{"name":"The Lancet. Child & adolescent health","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149248324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcomes of hepatic artery thrombosis after paediatric liver transplantation (HEPATIC): an international, multicentre, retrospective registry study.","authors":"Weihao Li, Hermien Hartog, Julia Minetto, Marcelo Dip, Emmanuel Gonzales, Florent Guérin, Ane M Andres, Francisco Hernandez-Oliveros, Catalina Jaramillo, Arielle Melen, Norman Junge, Ulrich Baumann, Joseph DiNorcia, Sander Florman, João Seda-Neto, Eduardo Antunes da Fonseca, George Mazariegos, Renana Yemini, Martín de Santibañes, Jimmy Walker Uno, Tianyi Lin, Yuan Liu, Lucie Gonsorčíková, Šimon Bohuš, Girish L Gupte, Simon P McGuirk, Denise Aldrian, Jonathan Seisenbacher, Barbara E Wildhaber, Ana M Calinescu, Mukesh Kumar, Subhash Gupta, Tingbo Liang, Wei Zhang, Paolo Marra, Lorenzo D'Antiga, Marisa Beretta, Francisca van der Schyff, Cristina T Ferreira, Marco A Farina, Jesús Quintero, Maria Mercadal-Hally, Winita Hardikar, Lynette Goh, Dieter C Broering, Dimitri A Raptis, Amit A Shah, Bryanna Domenick, Arti Pawaria, Marco Spada, Tommaso Alterio, Thomas Casswall, Carl Jorns, Muthukumarassamy Rajakannu, Mohamed Rela, Riccardo Superina, Juan Carlos Caicedo, Khaled Z Dajani, Alessandro Parente, Vidyadhar Mali, Marion M Aw, Sonal Asthana, Naveen Ganjoo, Yusuke Yanagi, Hajime Uchida, Gibson C Ugwu, Gerton A Lunter, Reinoud P H Bokkers, Hubert P J van der Doef","doi":"10.1016/S2352-4642(26)00218-X","DOIUrl":"https://doi.org/10.1016/S2352-4642(26)00218-X","url":null,"abstract":"<p><strong>Background: </strong>Hepatic artery thrombosis after paediatric liver transplantation is a severe complication that can lead to acute graft failure, often requiring urgent re-transplantation. We aimed to assess the 1-year incidence of graft loss and mortality and to evaluate outcomes according to the timing of hepatic artery thrombosis and the treatment approaches in patients with hepatic artery thrombosis after paediatric liver transplantation.</p><p><strong>Methods: </strong>In this international, multicentre, retrospective study, the HEPATIC registry, which had 33 centres across 21 countries as of December, 2025, was used to identify patients who developed hepatic artery thrombosis at age younger than 18 years after paediatric liver transplantation between Jan 1, 2002, and Dec 31, 2021, and who either received a diagnosis of or received an intervention for hepatic artery thrombosis before Jan 1, 2023. Donor-related, recipient-related, and transplantation-related characteristics collected from local medical records were entered retrospectively into electronic case reports by participating centres, with centralised data quality control. Primary outcomes were 1-year graft loss and mortality after hepatic artery thrombosis diagnosis. The outcomes were examined based on when hepatic artery thrombosis occurred after paediatric liver transplantation (early [≤7 days] vs late [>7 days]), primary management strategy (conservative management, surgical revascularisation, endovascular therapy, or immediate listing for re-transplantation), and transplantation era (in 5-year intervals). The registry was registered with ClinicalTrials.gov, NCT05818644.</p><p><strong>Findings: </strong>Hepatic artery thrombosis occurred in 415 patients, of whom 216 (52%) were female and 199 (48%) were male, and median age was 1·7 years (IQR 0·8-6·5). Median follow-up was 50·9 months (IQR 17·0-112·6). Graft loss occurred in 180 patients by 1 month (cumulative incidence 43% [95% CI 38-48]) and 222 by 1 year (54% [49-58]); 51 patients died by 1 month (12% [9-15]) and 77 by 1 year (19% [15-22]). Surgical revascularisation was the first-line treatment approach in 195 (47%) patients. Other strategies included listing for re-transplantation in 99 (24%), conservative management in 79 (19%), and endovascular therapy in 42 (10%). Treatment approaches changed over time, with increased use of conservative management and endovascular therapy and reduced listing for re-transplantation (p<0·0001), with no accompanying change in 1-year mortality across eras (p=0·14). Early (≤7 days) hepatic artery thrombosis occurred in 282 (68%) patients and was associated with higher 1-year graft loss than late (>7 days) hepatic artery thrombosis (cumulative incidence 57% [95% CI 51-63] vs 47% [37-55], log-rank p=0·010). Surgical revascularisation was used in 167 (59%) patients and listing for re-transplantation in 66 (23%) patients with early hepatic artery thrombosis, whereas conservative manag","PeriodicalId":94246,"journal":{"name":"The Lancet. Child & adolescent health","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149187281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Paediatric liver transplantation: the risk of hepatic artery thrombosis.","authors":"Emma C Alexander","doi":"10.1016/S2352-4642(26)00243-9","DOIUrl":"https://doi.org/10.1016/S2352-4642(26)00243-9","url":null,"abstract":"","PeriodicalId":94246,"journal":{"name":"The Lancet. Child & adolescent health","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149187392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Centring children and adolescents in drug policy development.","authors":"Ed Holt","doi":"10.1016/S2352-4642(26)00264-6","DOIUrl":"https://doi.org/10.1016/S2352-4642(26)00264-6","url":null,"abstract":"","PeriodicalId":94246,"journal":{"name":"The Lancet. Child & adolescent health","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149129731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Protecting children from meningitis: maintaining momentum","authors":"Talha Burki","doi":"10.1016/s2352-4642(26)00261-0","DOIUrl":"https://doi.org/10.1016/s2352-4642(26)00261-0","url":null,"abstract":"","PeriodicalId":94246,"journal":{"name":"The Lancet. Child & adolescent health","volume":"36 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149089173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Growing up with congenital Zika syndrome","authors":"Joris Hemelaar","doi":"10.1016/s2352-4642(26)00244-0","DOIUrl":"https://doi.org/10.1016/s2352-4642(26)00244-0","url":null,"abstract":"","PeriodicalId":94246,"journal":{"name":"The Lancet. Child & adolescent health","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149089273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mental health and urinary incontinence in childhood","authors":"Carol Joinson,Mauro Van den Ende,Sonya S Brady,Sanjay Sinha,Desiree Vrijens,Davina Richardson,Anna Page,Carsten Leue,Alexander von Gontard","doi":"10.1016/s2352-4642(26)00219-1","DOIUrl":"https://doi.org/10.1016/s2352-4642(26)00219-1","url":null,"abstract":"","PeriodicalId":94246,"journal":{"name":"The Lancet. Child & adolescent health","volume":"36 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149089181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Growth patterns of children with congenital Zika syndrome in Brazil: a matched-cohort study","authors":"Juliana Freitas de Mello e Silva,Helena Benes Matos da Silva,Luciana Lobato Cardim,Mariana Ramos Pitta Lima,Rita Carvalho-Sauer,Maria da Conceição Nascimento Costa,Elizabeth B Brickley,Bethania de Araujo Almeida,Laura C Rodrigues,Maria da Glória Teixeira,Rita de Cássia Ribeiro Silva,Mauricio Lima Barreto,Enny S Paixão","doi":"10.1016/s2352-4642(26)00214-2","DOIUrl":"https://doi.org/10.1016/s2352-4642(26)00214-2","url":null,"abstract":"","PeriodicalId":94246,"journal":{"name":"The Lancet. Child & adolescent health","volume":"37 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149089178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safety, antiviral activity, and pharmacokinetics of long-acting cabotegravir plus long-acting rilpivirine in virologically suppressed adolescents living with HIV-1 (IMPAACT 2017/MOCHA): week 96 and end-of-study results from a multinational, phase 1/2, single-arm trial","authors":"Carolyn Bolton Moore,Kristin Baltrusaitis,Edmund V Capparelli,Elizabeth D Lowenthal,Dwight E Yin,John H Moye,Christiana Smith,Michael Whitton,Conn M Harrington,Herta Crauwels,Rodica Van Solingen-Ristea,Mark A Marzinke,Barbara Heckman,Andi Ace,Shawn Ward,Kyle Whitson,Jenny Huang,S Y Amy Cheung,Brookie M Best,Ellen Townley,Allison Agwu,Pradthana Ounchanum,Sisinyana Ruth Mathiba,Linda Aurpibul,Violet Korutaro,Gaerolwe Masheto,Faeezah Patel,Evette Moodley,Aditya H Gaur,Avy Violari,Maxensia Owor,Kulkanya Chokephaibulkit,Andres Camacho-Gonzalez,Mary Paul,Samantha Fry,Jennifer Jao,Charles Mitchell,Sara Zabih,Veerle Van Eygen,Kati Vandermeulen,Ann Buchanan,Yu-Wei Lin,Kelong Han,Jon Collins,Chelsea Stotz,Rachel Scheckter,Sarah Buisson","doi":"10.1016/s2352-4642(26)00221-x","DOIUrl":"https://doi.org/10.1016/s2352-4642(26)00221-x","url":null,"abstract":"","PeriodicalId":94246,"journal":{"name":"The Lancet. Child & adolescent health","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149089172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}